http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Kim, Domyoung,Kwon, Seok-Joon,Wu, Xia,Sauve, Jessica,Lee, Inseon,Nam, Jahyun,Kim, Jungbae,Dordick, Jonathan S. American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.16
<P>Broad-spectrum antibiotics indiscriminately kill bacteria, removing nonpathogenic microorganisms and leading to evolution of antibiotic resistant strains. Specific antimicrobials that could selectively kill pathogenic bacteria without targeting other bacteria in the natural microbial community or microbiome may be able to address this concern. In this work, we demonstrate that silver nanoparticles, suitably conjugated to a selective cell wall binding domain (CBD), can efficiently target and selectively kill bacteria. As a relevant example, CBD<SUP>BA</SUP> from <I>Bacillus anthracis</I> selectively bound to <I>B. anthracis</I> in a mixture with <I>Bacillus subtilis</I>, as well in a mixture with <I>Staphylococcus aureus</I>. This new biologically-assisted hybrid strategy, therefore, has the potential to provide selective decontamination of pathogenic bacteria with minimal impact on normal microflora.</P> [FIG OMISSION]</BR>
Large-Area Nanosquare Arrays from Shear-Aligned Block Copolymer Thin Films
Kim, So Youn,Nunns, Adam,Gwyther, Jessica,Davis, Raleigh L.,Manners, Ian,Chaikin, Paul M.,Register, Richard A. American Chemical Society 2014 NANO LETTERS Vol.14 No.10
<P>While block copolymer lithography has been broadly applied as a bottom-up patterning technique, only a few nanopattern symmetries, such as hexagonally packed dots or parallel stripes, can be produced by spontaneous self-assembly of simple diblock copolymers; even a simple square packing has heretofore required more intricate macromolecular architectures or nanoscale substrate prepatterning. In this study, we demonstrate that square, rectangular, and rhombic arrays can be created via shear-alignment of distinct layers of cylinder-forming block copolymers, coupled with cross-linking of the layers using ultraviolet light. Furthermore, these block copolymer arrays can in turn be used as templates to fabricate dense, substrate-supported arrays of nanostructures comprising a wide variety of elements: deep (>50 nm) nanowells, nanoposts, and thin metal nanodots (3 nm thick, 35 nm pitch) are all demonstrated.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2014/nalefd.2014.14.issue-10/nl502416b/production/images/medium/nl-2014-02416b_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl502416b'>ACS Electronic Supporting Info</A></P>
The Effect of Consumer Motivations on Purchase Intention of Online Fashion - Sharing Platform
WON, Jessica,KIM, Bo-Young Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.6
This study aims to examine the influence of attitudes on customers' intention to participate in online fashion sharing. A framework was proposed to investigate the relationships between consumer motivation, consumer attitude, and purchase intention in the manner of adopting a fashion-sharing platform. Consumer motivations are divided into three categories: utilitarian, hedonic, and ecological. The moderating effects of product replacement cycle (PRC) on consumer attitude and purchase intention are also investigated. Data collection was developed using a web-based survey where 180 consumer respondents from South Korea participated. The results of our analysis indicate that consumers' hedonic and ecological motivations are positively related to favorable consumer attitudes, even when consumers' utilitarian motivation is denied. Consumer attitude is also positively related to purchase intention in the fashion-sharing platform. A moderating effect of PRC is recorded between consumer attitude and purchase intention based on high and low PRC, as well as the effect of ecological motivation and consumer attitude on high PRC. This study enhances knowledge of consumer motivational factors in a fashion-sharing platform and provides insights for service providers to help them improve their target marketing.
Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity
Lee, HyeJin,Kim, Jungeun,Weber, Jessica A.,Chung, Oksung,Cho, Yun Sung,Jho, Sungwoong,Jun, JeHoon,Kim, Hak-Min,Lim, Jeongheui,Choi, Jae-Pil,Jeon, Sungwon,Blazyte, Asta,Edwards, Jeremy S.,Paek, Woon Ke Korean Society for Molecular and Cellular Biology 2020 Molecules and cells Vol.43 No.1
The red-crowned crane (Grus japonensis) is an endangered, large-bodied crane native to East Asia. It is a traditional symbol of longevity and its long lifespan has been confirmed both in captivity and in the wild. Lifespan in birds is known to be positively correlated with body size and negatively correlated with metabolic rate, though the genetic mechanisms for the red-crowned crane's long lifespan have not previously been investigated. Using whole genome sequencing and comparative evolutionary analyses against the grey-crowned crane and other avian genomes, including the long-lived common ostrich, we identified redcrowned crane candidate genes with known associations with longevity. Among these are positively selected genes in metabolism and immunity pathways (NDUFA5, NDUFA8, NUDT12, SOD3, CTH, RPA1, PHAX, HNMT, HS2ST1, PPCDC, PSTK CD8B, GP9, IL-9R, and PTPRC). Our analyses provide genetic evidence for low metabolic rate and longevity, accompanied by possible convergent adaptation signatures among distantly related large and long-lived birds. Finally, we identified low genetic diversity in the red-crowned crane, consistent with its listing as an endangered species, and this genome should provide a useful genetic resource for future conservation studies of this rare and iconic species.
Hypothalamic primary cilium: A hub for metabolic homeostasis
양동주,Hong Jessica,Kim Ki Woo 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-
Obesity is a global health problem that is associated with adverse consequences such as the development of metabolic disorders, including cardiovascular disease, neurodegenerative disorders, and type 2 diabetes. A major cause of obesity is metabolic imbalance, which results from insufficient physical activity and excess energy intake. Understanding the pathogenesis of obesity, as well as other metabolic disorders, is important in the development of methods for prevention and therapy. The coordination of energy balance takes place in the hypothalamus, a major brain region that maintains body homeostasis. The primary cilium is an organelle that has recently received attention because of its role in controlling energy balance in the hypothalamus. Defects in proteins required for ciliary function and formation, both in humans and in mice, have been shown to cause various metabolic disorders. In this review, we provide an overview of the critical functions of primary cilia, particularly in hypothalamic areas, and briefly summarize the studies on the primary roles of cilia in specific neurons relating to metabolic homeostasis.