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      • Biosensor <i>system</i>-<i>on</i>-<i>a</i>-<i>chip</i> including CMOS-based signal processing circuits and 64 carbon nanotube-based sensors for the detection of a neurotransmitter

        Lee, Byung Yang,Seo, Sung Min,Lee, Dong Joon,Lee, Minbaek,Lee, Joohyung,Cheon, Jun-Ho,Cho, Eunju,Lee, Hyunjoong,Chung, In-Young,Park, Young June,Kim, Suhwan,Hong, Seunghun Royal Society of Chemistry 2010 Lab on a chip Vol.10 No.7

        <P>We developed a carbon nanotube (CNT)-based biosensor <I>system</I>-<I>on</I>-<I>a</I>-<I>chip</I> (SoC) for the detection of a neurotransmitter. Here, 64 CNT-based sensors were integrated with silicon-based signal processing circuits in a single chip, which was made possible by combining several technological breakthroughs such as <I>efficient signal processing</I>, <I>uniform CNT networks</I>, and <I>biocompatible functionalization of CNT</I>-<I>based sensors</I>. The chip was utilized to detect glutamate, a neurotransmitter, where ammonia, a byproduct of the enzymatic reaction of glutamate and glutamate oxidase on CNT-based sensors, modulated the conductance signals to the CNT-based sensors. This is a major technological advancement in the integration of CNT-based sensors with microelectronics, and this chip can be readily integrated with larger scale lab-on-a-chip (LoC) systems for various applications such as LoC systems for neural networks.</P> <P>Graphic Abstract</P><P>Uniform arrays of carbon nanotube (CNT)-based biosensors were integrated with CMOS signal-processing circuits into a CNT-biosensor system-on-a-chip (SoC) for the detection of glutamate, a neurotransmitter. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b916975j'> </P>

      • Modified Aloe Polysaccharide Restores Chronic Stress-Induced Immunosuppression in Mice

        Lee, Youngjoo,Im, Sun-A,Kim, Jiyeon,Lee, Sungwon,Kwon, Junghak,Lee, Heetae,Kong, Hyunseok,Song, Youngcheon,Shin, Eunju,Do, Seon-Gil,Lee, Chong-Kil,Kim, Kyungjae MDPI 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.17 No.10

        <P>Chronic stress generally experienced in our daily lives; is known to augment disease vulnerability by suppressing the host immune system. In the present study; the effect of modified Aloe polysaccharide (MAP) on chronic stress-induced immunosuppression was studied; this Aloe compound was characterized in our earlier study. Mice were orally administered with MAP for 24 days and exposed to electric foot shock (EFS; duration; 3 min; interval; 10 s; intensity; 2 mA) for 17 days. The stress-related immunosuppression and restorative effect of MAP were then analyzed by measuring various immunological parameters. MAP treatment alleviated lymphoid atrophy and body weight loss. The numbers of lymphocyte subsets were significantly normalized in MAP-treated mice. Oral administration of MAP also restored the proliferative activities of lymphocytes; ovalbumin (OVA)-specific T cell proliferation; antibody production; and the cell killing activity of cytotoxic T lymphocytes. In summary; oral administration of MAP ameliorated chronic EFS stress-induced immunosuppression.</P>

      • THE EFFECT OF THE ATTRIBUTES OF IT SHOPPING SERVICE AND THE LEVEL OF TECHNOLOGY ON CUSTOMER RESPONSES IN FASHION RETAIL

        Sooyeon Lee,Miah Lee,Eunju Ko,Sangwon Lee 글로벌지식마케팅경영학회 2014 Global Marketing Conference Vol.2014 No.7

        According to the development of information technology (IT) and new media, customers’ needs have changed to seek not only high quality goods but also a differentiated service in retail stores (Lee & Shin, 2011). For this reason, fashion retail stores started to provide an interesting service by setting up an IT machine or a gadget in the stores. Thereby, customers can get the information or have a special experience while they shop fashion goods. IT shopping service is defined as using technology in retail stores to enhance interaction between retailers and customers. Retailers have tried several types of IT shopping services, which offer information or experience with a high or low level of technology. Informative IT shopping service provides various and useful information, which is related to each product such as size, color, contents, stock, location and fashion styling. Retailers use experiential IT shopping service as an emotional appeal that gives direct experience to customers in some way or other such as watching or acting in a virtual situation. Also, as technology develops, IT shopping services are embodied with diverse technology that are simple or complexity. Some are easy to use with one button and shows 2D images only, but some have a lot of contents such as video clips, SNS share service, showing 3D images, and implementing augment reality. We saw customer responses on the attributes of IT shopping service (informative vs. experimental) x technology level of IT shopping service (high vs. low) x fashion innovativeness/technology innovativeness (high vs. low) This study aims to see the effect of the attributes of IT shopping service and the level of technology on procedure satisfaction and outcome satisfaction, and the moderating effect of perceived enjoyment and perceived complexity. Furthermore, this study will see whether these effects affect visit intention. In this study, the experimental design was adopted as the main methodology, and a total of four stimuli types were selected: 1) informative x high technology 2) informative x low technology 3) experiential x high technology 4) experiential x low technology. The common element, which all types of stimuli have, is a digital touch screen since it is a general equipment nowadays, and the common fashion good for all types is a black blazer. The type of informative service only has the information (size range, color assortment, contents, stock) about selected fashion good with its image. High technology in informative service shows the image with 3D simulation that can help to see 360° of the blazer, and styling tips including a video clip. Moreover, it helps to share the information with friends via SNS. Low technology in informative service only shows a front side of the blazer and presents a store map for customers to find a product they want to try. The types of experiential service draw customer participation providing a picture of customers that are trying on clothes. Experiential service use augment reality (AR) as a high technology and take the back side of customers picture as low technology. For the manipulation check, 18 graduate students in total viewed for each type, and the total sample comprises 387 college students via survey instrument. All hypotheses were tested using AMOS and SPSS 18.0. The main findings of this study are as follows: depending on type of the attributes of IT shopping service and the level of technology affect perceived enjoyment and perceived complexity differently, and there were significant mediating effect of perceived variables toward IT shopping service on procedure satisfaction, outcome satisfaction, and visit intention. Implications for usefulness and role of the IT shopping service in fashion retail stores are provided. And also, limitation of this study and future study are suggested.

      • THE EFFECT OF THE ATTRIBUTES OF IT SHOPPING SERVICE AND THE LEVEL OF TECHNOLOGY ON CUSTOMER RESPONSES IN FASHION RETAIL

        Sooyeon Lee,Miah Lee,Eunju Ko,Sangwon Lee 글로벌지식마케팅경영학회 2014 Global Marketing Conference Vol.2014 No.6

        According to the development of information technology (IT) and new media, customers’ needs have changed to seek not only high quality goods but also a differentiated service in retail stores (Lee & Shin, 2011). For this reason, fashion retail stores started to provide an interesting service by setting up an IT machine or a gadget in the stores. Thereby, customers can get the information or have a special experience while they shop fashion goods. IT shopping service is defined as using technology in retail stores to enhance interaction between retailers and customers. Retailers have tried several types of IT shopping services, which offer information or experience with a high or low level of technology. Informative IT shopping service provides various and useful information, which is related to each product such as size, color, contents, stock, location and fashion styling. Retailers use experiential IT shopping service as an emotional appeal that gives direct experience to customers in some way or other such as watching or acting in a virtual situation. Also, as technology develops, IT shopping services are embodied with diverse technology that are simple or complexity. Some are easy to use with one button and shows 2D images only, but some have a lot of contents such as video clips, SNS share service, showing 3D images, and implementing augment reality. We saw customer responses on the attributes of IT shopping service (informative vs. experimental) x technology level of IT shopping service (high vs. low) x fashion innovativeness/technology innovativeness (high vs. low) This study aims to see the effect of the attributes of IT shopping service and the level of technology on procedure satisfaction and outcome satisfaction, and the moderating effect of perceived enjoyment and perceived complexity. Furthermore, this study will see whether these effects affect visit intention. In this study, the experimental design was adopted as the main methodology, and a total of four stimuli types were selected: 1) informative x high technology 2) informative x low technology 3) experiential x high technology 4) experiential x low technology. The common element, which all types of stimuli have, is a digital touch screen since it is a general equipment nowadays, and the common fashion good for all types is a black blazer. The type of informative service only has the information (size range, color assortment, contents, stock) about selected fashion good with its image. High technology in informative service shows the image with 3D simulation that can help to see 360º of the blazer, and styling tips including a video clip. Moreover, it helps to share the information with friends via SNS. Low technology in informative service only shows a front side of the blazer and presents a store map for customers to find a product they want to try. The types of experiential service draw customer participation providing a picture of customers that are trying on clothes. Experiential service use augment reality (AR) as a high technology and take the back side of customers picture as low technology. For the manipulation check, 18 graduate students in total viewed for each type, and the total sample comprises 387 college students via survey instrument. All hypotheses were tested using AMOS and SPSS 18.0. The main findings of this study are as follows: depending on type of the attributes of IT shopping service and the level of technology affect perceived enjoyment and perceived complexity differently, and there were significant mediating effect of perceived variables toward IT shopping service on procedure satisfaction, outcome satisfaction, and visit intention. Implications for usefulness and role of the IT shopping service in fashion retail stores are provided. And also, limitation of this study and future study are suggested.

      • KCI등재

        Anesthetic course and complications that were encountered during endoscopic thyroidectomy -A case report-

        Su-Nam Lee,Ji- Heui Lee,Eunju Lee,Ji-Yeon Lee,Jong-il Kim,Youbin Son 대한마취통증의학회 2012 Korean Journal of Anesthesiology Vol.63 No.4

        Endoscopic thyroidectomy is gaining popularity, but it can increase the risk of certain complications. Carbon dioxide insufflation in the neck may cause adverse effects on hemodynamic and ventilatory aspects. We report the anesthetic course and complications that were encountered during endoscopic thyroidectomy. Although the surgery was successful, the patient developed signs of hypercarbia, subcutaneous emphysema and pneumothorax.

      • SCISCIESCOPUS

        Aloe QDM complex enhances specific cytotoxic T lymphocyte killing <i>in vivo</i> in metabolic disease mice

        Lee, Youngjoo,Kim, Jiyeon,An, Jinho,Lee, Heetae,Kong, Hyunseok,Song, Youngcheon,Shin, Eunju,Do, Seon-Gil,Lee, Chong-Kil,Kim, Kyungjae Taylor & Francis 2017 Bioscience, Biotechnology, and Biochemistry Vol. No.

        <P>We developed spontaneous diet-induced metabolic disease in mice by feeding them a high-fat diet for 23weeks and administered Aloe QDM complex for 16weeks to examine its restorative effect on immune disorders and metabolic syndrome. A series of immune functional assays indicated Aloe QDM complex enhanced lymphocyte proliferation and antigen-specific immunity as determined by the restored functions of cytotoxic T lymphocytes (CTL) and IgG production. The elevated serum TNF- level was also regulated by Aloe QDM complex treatment, which suggested its complex therapeutic potential. As for metabolic phenotypes, oral administration of Aloe QDM complex significantly improved diabetic symptoms, including high fasting glucose levels and glucose tolerance, and distinctly alleviated lipid accumulation in adipose and hepatic tissue. The simultaneous restoration of Aloe QDM complex on metabolic syndrome and host immune dysfunction, especially on the specific CTL killing was first elucidated in our study.</P>

      • SUSTAINABLE FASHION PRODUCT DEVELOPMENT USING THE PLM APPROACH

        Eunju Ko,Jinghe Han,Eunha Chun,Minyoung Lee 글로벌지식마케팅경영학회 2016 Global Marketing Conference Vol.2016 No.7

        The ever-evolving fashion industry has brought forth direct and indirect effects on the environmentto the extent that environmental contamination, labor exploitation, and pirated or counterfeit products have emerged as serious social issues. The sustainability-related issues are associated with all stages of the product lifecycle, ranging from the extraction of raw materials to product disposal (Berkhout & Smith, 1999).In lifecycle management (LCM), the triple bottom line (TBL) of sustainability is seen from the perspective of the product lifecycle (Kocmanova & Nemecek, 2009). TBL refers to corporate efforts to keep a balance among financial viability, environmental soundness and social accountability (Elkington, 1997). As sustainable products are defined in the light of lifecycles, research on product lifecycle management (PLM) has drawn much attention (Gmelin & Seuring, 2014).In addition, PLM is known to exert substantial effects on new product development, which warrants the need to view new sustainable products from the perspective of PLM (Cantamessa, Montagna, & Neirotti, 2012). Therefore, the present study intends to apply a conceptual model of PLM-based new sustainable product development to the fashion industry and to take multifaceted approaches to sustainable fashion product development. To that end, case studies of 21 local and global sustainable fashion brands, 1:1 in-depth interviews with 24 experts from sustainable and non-sustainable fashion brands, and participant observation of 5 sustainable fashion brands were conducted as part of this study. The findings illuminate the management issues attributable to the lack of technology and expertise, as well as the quantification issues involving monitoring or normalized data collection, despite the presence of some process-specific sustainable items in sustainable products developed by the fashion brands. Also, the findings will serve as reference data for further discussions and provide some implications for the sustainable fashion product development of fashion brands.

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