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( Chong Wei Li ),( Rui Qing Song ),( Li Bin Yang ),( Xun Deng ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.8
Trichoderma strain T-33 has been demonstrated to have inhibitory effect on the fungus species Cytospora chrysosperma. Here, an active antifungal compound was obtained from Trichoderma strain T-33 extract via combined separation technologies, including organic solvent extraction, liquid chromatography, and thin-layer chromatography. The purified compound was further characterized by advanced analytical technologies to elucidate its chemical structure. Results indicated that the active antifungal compound in Trichoderma strain T-33 extract is 2,5-cyclohexadiene-1,4-dione-2,6-bis (1,1-dimethylethyl).
Du, Wei,Ma, Xue-Lei,Zhao, Chong,Liu, Tao,Du, Yu-Liang,Kong, Wei-Qi,Wei, Ben-Ling,Yu, Jia-Yun,Li, Yan-Yan,Huang, Jing-Wen,Li, Zi-Kang,Liu, Lei Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2
Background: MicroRNAs (miRNAs) are an abundant class of endogenous small non-coding RNAs of 20-25 nucleotides in length that function as negative gene regulators. MiRNAs play roles in most biological processes, as well as diverse human diseases including cancer. Recently, many studies investigated the association between SNPs in miR-146a rs2910164, miR-196a2 rs11614913, miR-149 rs229283, miR-499 rs3746444 and colorectal cancer (CRC), which results have been inconclusive. Methodology/Principal Findings: PubMed, EMBASE, CNKI databases were searched with the last search updated on November 5, 2013. For miR-196a2 rs11614913, a significantly decreased risk of CRC development was observed under three genetic models (dominant model: OR = 0.848, 95%CI: 0.735-0.979, P = 0.025; recessive model: OR = 0.838, 95%CI: 0.721-0.974, P = 0.021; homozygous model: OR = 0.754, 95%CI: 0.627-0.907, P = 0.003). In the subgroup analyses, miR-$196a2^*T$ variant was associated with a significantly decreased susceptibility of CRC (allele model: OR = 0.839, 95%CI: 0.749-0.940, P = 0.000; dominant model: OR = 0.770, 95%CI: 0.653-0.980, P = 0.002; recessive model: OR = 0.802, 95%CI: 0.685-0.939, P = 0.006; homozygous model: OR = 0.695, 95%CI: 0.570-0.847, P = 0.000). As for miR-149 rs2292832, the two genetic models (recessive model: OR = 1.199, 95% CI 1.028-1.398, P = 0.021; heterozygous model: OR = 1.226, 95% CI 1.039-1.447, P = 0.013) demonstrated increased susceptibility to CRC. On subgroup analysis, significantly increased susceptibility of CRC was found in the genetic models (recessive model: OR = 1.180, 95% CI 1.008-1.382, P = 0.040; heterozygous model: OR = 1.202, 95% CI 1.013-1.425, P = 0.013) in the Asian group. Conclusions: These findings supported that the miR-196a2 rs11614913 and miR-149 rs2292832 polymorphisms may contribute to susceptibility to CRC.
Jin-Hua Liang,Yun-Ping Zhang,Jun Xia,Chong-Yang Ding,Wei Wu,Li Wang,Lei Cao,Hua-Yuan Zhu,Lei Fan,Tian-Nv Li,Jian-Yong Li,Wei Xu 대한암학회 2019 Cancer Research and Treatment Vol.51 No.4
Purpose The purpose of this study was to investigate the prognostic significance of total metabolic tumor volume (TMTV) and total lesion glycolysis (TLG) in patients with follicular lymphoma (FL) at baseline and mid-treatment with 18F-fluorodeoxyglucose positron emission tomography computed tomography (PET-CT) scans. Materials and Methods The study analyzed data from 48 patients with FL who were treated in Jiangsu Province Hospital and reviewed their baseline PET-CT scans. TMTV and TLG were computed by using the absolute value of 2.0, 2.5, and 3.0 thresholding method, respectively. Results Median age was 53 years, 75.0% of patients had stage III to IV disease, 43.8% had a Follicular Lymphoma International Prognostic Index 1 (FLIPI1) score of 3 to 5 and 20.8% had a FLIPI2 score of 3 to 5. Receiver operating characteristic (ROC) curve analysis showed the optimal cut-off values for TMTV3.0 and TLG3.0 were 476.4 (sensitivity, 85.7%; specificity, 78.0%; area under the curve [AUC], 0.760; p=0.003) and 2,676.9 (sensitivity, 71.4%; specificity, 78.0%; AUC, 0.760; p=0.003). On multivariable analysis, TMTV3.0 and TLG3.0 were independent predictors of both progression-free survival (PFS) (hazard ratio [HR], 5.406; 95% confidence interval [CI], 1.326 to 22.040; p=0.019 and HR, 6.502; 95% CI, 1.079 to 39.182; p=0.042) and overall survival (OS) (HR, 4.111; 95% CI, 1.125 to 15.027; p=0.033 and HR, 5.885; 95% CI, 1.014 to 34.148; p=0.049). ROC curve analysis showed the optimal cut-off values for TMTV3.0 and TLG3.0 were 66.3% (sensitivity, 85.7%; specificity, 63.4%; AUC, 0.774; p < 0.001) and 64.5% (sensitivity, 85.7%; specificity, 65.9%; AUC, 0.777; p < 0.001). Conclusion Baseline TMTV and TLG are strong predictors of PFS and OS in FL. Furthermore, interim TMTV (TMTV > 66.3%) and TLG (TLG > 64.5%) reduction are valuable tools for early treatment response assessment in FL patients.
Chong Yao,Xiao-Dong Qian,Gui-Fen Zhou,Shu-Wei Zhang,Li-Qin Li,Qiaosheng Guo 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.2
The red stigmas of saffron are one of the mostexpensive spices in the world and serve as a traditionalChinese medicine. More saffron has been cultivated inChina, and different drying technologies have been studied. However, a comprehensive and comparative analysis ofdifferent drying approaches has not been well studied. Inthis study, we compared electric oven and vacuum ovendrying approaches on saffron. We found saffron was driedquicker under high vacuum drying mode with high temperatureand the quicker drying rate provided, the moreopen microstructural interstices on the saffron surface. Both methods were best fit to Midilli and Kucuk model. Besides, the coloring, aroma and bitterness strength afterdrying showed the similar results. In sum, our data suggestedthe optimal drying temperature was 100 C for20 min for two evaluated methods, however consideringthe machine cost, the electric oven drying would be the firstchoice.
Li Wang,Xuejing Zhang,JunHu Yang,Chong Ma,Wei Han,Yubing Gong 한국유체기계학회 2023 International journal of fluid machinery and syste Vol.16 No.2
When GVF in the inlet of the oil-gas mixed transmission twin-screw pump is high, the temperature difference between the inlet and outlet of the screw pump will rise significantly, and rotor expansion jam will occur. To prevent the expansion jam caused by the overheating of the screw pump, the cooling water jacket is designed for gas-liquid mixed screw pump with high GVF to continuously cool. Using the theory of fluid-structure interaction heat transfer, the cooling effect of the cooling water jacket of the equal pitch screw pump and the variable pitch screw pump is numerically calculated, and after comparison with the experiment, it finds that the maximum deviation of the outlet temperature of the variable pitch screw pump does not exceed 4K and the average deviation is about 6 %. When GVF is 96%, the calculation of the cooling water cavity shows that the average temperature drop of the liner after the cooling of the equal pitch screw pump and the variable pitch screw pump is about 4K and 3K, respectively. When GVF rises from 90% to 99%, the average temperature drop is about 3.5K. Cooling water jacket has obvious cooling effect on screw pump with high GVF.
The diathermy scratch pad: A cheap and efficient tool for chemical and explosion-related burns
Allen Wei-Jiat Wong,Qi En Hong,Cheryl Li Yu Hui,Si Jack Chong 대한성형외과학회 2019 Archives of Plastic Surgery Vol.46 No.1
The burn center in our hospital is a national and regional (Southeast Asia) center. Of all admissions, 10% are related to blast explosions, and 8% due to chemical burns. In the acute burn management protocol of Singapore General Hospital, early surgical debridement is advocated for all acute partial-thickness burns. The aim of early surgical debridement is to remove all debris and unhealthy tissue, preventing wound infection and thereby expediting wound healing. In chemical burns, there can be stubborn eschars that are resistant to traditional debridement. We would like to present a novel technique using the diathermy scratch pad as a cheap and efficient tool for the dual purpose of surgical debridement and dermabrasion.
CONTROL SYSTEM OF THREE DIMENSIONAL HYDRAULIC SIMULATIVE ROCKING TEST-BED
Jiang, Chong Li,Ye, Wei Dong,Ming, Dong,Zhou, Hai Yang,Wang, Xiao Hui 대한전자공학회 1992 HICEC:Harbin International Conference on Electroni Vol.1 No.1
Three dimensional hydraulic simulative rocking test-bed is an experiment tool. It is drived by three dimensional hydraulic pressure, it could be applied to simulate various decline and rocking conditions to actual marine on sea as true as possible. It is vital test means to the equipments on the marine which need examination to decline and rocking condition. It is high accurate, safe, and convenient. By computer control, we strenghen the mobility of system, increase accuracy of trace, widen using scope. In this paper, we introduce sinuous servo system controlled by computer, system design, composition of system, stability analysis, program design, data processing and screen display.
Experimental study on performance of steam-water injector with central water nozzle arrangement
Wen Jun Li,Dao Tong Chong,Jun Jie Yan,Wei Xiong Chen,Jin Shi Wang 한국화학공학회 2014 Korean Journal of Chemical Engineering Vol.31 No.9
The steam-water injector (SI) is a simple mechanical device that has been widely used in industry. Wedid an experimental study to find the influence of physical and geometrical parameters on performance of the SI. Thephysical parameters studied were steam inlet pressure, water inlet pressure and water inlet temperature. Whereas, thegeometrical parameters studied were steam nozzle area ratio, area ratio of steam nozzle to water nozzle and the mixingsection converging angle. Pump head was introduced to evaluate the lifting-pressure performance of the SI under dif-ferent operating and geometrical conditions. Optimal values of steam nozzle area ratio and mixing section convergingangle were 1.3 and 11.6orespectively, for the present work, and optimal value of area ratio of steam nozzle to waternozzle increased with increasing water inlet pressure. Two head-capacity curves were introduced to highlight the effectof various physical and geometrical parameters on the performance of SI.