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Theoretical model to determine bond loss in prestressed concrete with reinforcement corrosion
Néstor F. Ortega,Juan M. Moro,Romina S. Meneses 국제구조공학회 2018 Structural Engineering and Mechanics, An Int'l Jou Vol.65 No.1
This paper reviews the mechanical effects produced by reinforcement corrosion of prestressed concrete beams. Specifically, modifications in the bonding of the tendon to the concrete that reduce service life and load bearing capacity are studied. Experimental information gathered from previous works has been used for the theoretical analysis. Relationships between bond stress loss and reinforcement penetration in the concrete, and concrete external cracking were established. Also, it was analysed the influence that has the location of the area affected by corrosion on the loss magnitude of the initial prestress.
Carmela Puchol Estrugo,Miriam Trujillo Rodríguez,Nicolás Mendoza-Ladrón de Guevara,Joaquín Grande Gómez,Francisca Ridocci,Maria Teresa Moro-Martín,Misericordia Guinot,Paula Saz-Leal,Concepción Nieto M 대한폐경학회 2023 대한폐경학회지 Vol.29 No.2
Objectives: This study aims to investigate the effects of a combination of soy isoflavones, 8-prenylnaringenin (8-PN), and melatonin in postmenopausal women suffering from moderate-to-severe hot flashes (HFs).Methods: A multicenter, prospective, open-label study enrolled 44 postmenopausal women suffering from moderate-to-severe HFs (≥ 5 daily or ≥ 35 weekly) to receive 54.4 mg standardized soy isoflavones (including 24.5 mg genistein and 16.3 mg daidzein), 100 µg 8-PN, and 1 mg melatonin once daily for 12 weeks. The primary clinical outcomes included changes in health-related quality of life (HRQoL) scores (Menopause-Specific QoL questionnaire [MENQoL] and Cervantes Scale) and HFs following 4 and 12 weeks of treatment. Other analyses included treatment adherence, acceptability, tolerability, and safety.Results: All of the four domains of MENQoL questionnaire significantly improved at 4 weeks (P < 0.05) and 12 weeks (P < 0.001), affecting significantly the vasomotor, psychosocial, and physical spheres (41.2%, 26.3%, and 25.0%; 12 weeks improvements, respectively). Similarly, in the menopause (39.3%) and psychic (51.7%) domains (both P < 0.05 at 12 weeks), the global score of the Cervantes Scale significantly increased at 4 weeks (18.6%) and 12 weeks (35.4%). Accordingly, moderate-to-severe HFs significantly decreased at 4 weeks compared to baseline (41.7% reduction) and further reduced at 12 weeks (76.5%), including the total number of episodes.Conclusions: Food supplements containing soy isoflavones, 8-PN, and melatonin showed an early and progressive benefit for reducing clinically significant HFs and for improving HRQoL across all domains, favorably affecting postmenopausal women’s overall well-being.
David Moro-Valdezate,Salvador Peiró,Elvira Buch-Villa,Antonio Caballero-Gárate,M. Dolores Morales-Monsalve,Ángel Martínez-Agulló,Félix Checa-Ayet,Joaquín Ortega-Serrano 한국유방암학회 2013 Journal of breast cancer Vol.16 No.1
Purpose: The objective of this study was to describe the evolution of health-related quality of life (HRQOL) in a cohort of breast cancer patients over 1 year after surgery and to analyse the predictive ability of HRQOL measurement instruments. Methods: Observational, multicenter and prospective study of a cohort of breast cancer patients, assessing HRQOL at 1, 6, and 12 months after surgery using three questionnaires: EuroQol-5D-3L, EORTC QLQ-C30, and EORTC QLQ-BR23. Results: A total of 364 women participated in the study. Visual Analogue Scale (VAS) scores from the EuroQol improved (1 month vs. 1 year: 70 vs. 80; p<0.0001); however, the EuroQol score showed no significant change (0.81 vs. 0.83; p=0.1323). In contrast, Global Health Status on the EORTC QLQ-C30 improved (66.67 vs. 100.00; p<0.0001), as did all of this instrument´s scales and most of its independent items. The EORTC QLQ-BR23 dimensions showed improvement, except for sexual functioning (100.00 vs. 86.67; p=0.0030) and future perspective (33.33 vs. 66.67; p<0.0001). Patients with good HRQOL outcomes at 1 month showed improved levels of HRQOL at 1 year; HRQOL measured at 1 month was predictive of HRQOL at 1 year. Conclusion: HRQOL improved during the follow-up period. Likewise, HRQOL measurement instruments can predict early HRQOL.
Vicente Pla-Martí,Jose Martín-Arévalo,Rosa Martí-Fernández,David Moro-Valdezate,Stephanie García-Botello,Alejandro Espí-Macías,Miguel Mínguez-Pérez,Maria Dolores Ruiz-Carmona,Jose Vicente Roig-Vila 대한대장항문학회 2022 Annals of Coloproctolgy Vol.38 No.1
Purpose: This study was performed to evaluate the long-term evolution of continence and patient’s quality of life after surgical treatment for obstetric fecal incontinence. Methods: A prospective longitudinal study was conducted including consecutive patients who underwent sphincteroplasty for severe obstetric fecal incontinence. The first phase analyzed changes in continence and impact on quality of life. The second phase studied the long-term evolution reevaluating the same group of patients 6 years later. Degree of fecal incontinence was calculated using the Cleveland Clinic Score (CCS). Quality of life assessment was carried out with the Fecal Incontinence Quality of Life scale. Results: Thirty-five patients with median age of 55 years (range, 28 to 73 years) completed the study. Phase 1 results: after a postoperative follow-up of 30 months (4 to 132 months), CCS had improved significantly from a preoperative of 15.7±3.1 to 6.1±5.0 (P<0.001). Phase 2 results: median follow-up in phase 2 was 110 months (76 to 204 months). The CCS lowered to 8.4±4.9 (P=0.04). There were no significant differences between phases 1 and 2 in terms of quality of life; lifestyle (3.47± 0.75 vs. 3.16±1.04), coping/behavior (3.13±0.83 vs. 2.80±1.09), depression/self-perception (3.65±0.80 vs. 3.32± 0.98), and embarrassment (3.32±0.90 vs. 3.12±1.00). Conclusion: Sphincteroplasty offers good short-medium term outcomes in continence and quality of life for obstetric fecal incontinence treatment. Functional clinical results deteriorate over time but did not impact on patients’ quality of life.
Cho, Y.,Cole, R.,Ikaga, T.,Larsson, N.,Moro, A.,Rovers, R.,Shin, S. Sustainable Building Research Center 2010 International journal of sustainable building tech Vol.1 No.1
The purpose of the discussion is to enhance the understanding of importance of sustainable development in the industry and to expand the international relation on the technology of sustainable architecture. The theme of SB10 SEOUL conference, "Sustainable Building Assessment Technology and Strategies for Higher Education" is selected to expand the knowledge of the current condition and the direction of future in sustainable building assessment technology.
A New Allelic Variant in the PANK2 Gene in a Patient with Incomplete HARP Syndrome
Myriam Ley Martos,María Jesús Salado Reyes,Rosario Marín Iglesias,Carmen Gutiérrez Moro,Manuel Lubián Gutiérrez,Lorena Estepa Pedregosa 대한파킨슨병및이상운동질환학회 2020 Journal Of Movement Disorders Vol.13 No.3
Pantothenate kinase-associated neurodegeneration (PKAN) is a rare autosomal recessive disease characterized by iron deposition in the basal ganglia, primarily in the globus pallidus and substantia nigra. Common clinical manifestations include dystonia, parkinsonism, spasticity, neuropsychiatric disorders and retinal degeneration. PKAN is included in the spectrum of disorders related to neurodegeneration with brain iron accumulation (NBIA), which includes eleven diseases.