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( Cecilia Perez-cruz ),( Carlos N. Cano-gonzalez ),( Jose Fuentes ),( Nagamani Balagurusamy ),( Carolina E. Vita ),( Roque A. Hours ),( Cristobal N. Aguilar ),( Sebastian F. Cavalitto ),( Juan C. Cont 한국키틴키토산학회 2018 한국키틴키토산학회지 Vol.23 No.3
Aspergillus niger biomass, an industrial by-product of citric acid fermentation is an emergent source of glycoderivatives with applications in biofuel, cosmetics, feed, energy, food, medicine, and nanotechnology. In this study, the effect of purified neutral protease for deprotenization of fungal biomass studied at various levels (0, 5, 10, 20 and 40 U/100 mg of biomass) and the saccharification of fungal biomass was evaluated with amylolytic enzymes and chitosanases. The efficiency of deproteinization of fungal biomass was based on the enzyme concentration and contact time. Protease at a concentration of 20 U/100 mg of dry biomass and with a contact time of 8 h achieved 30% final deproteinization. No effect on saccharification of A. niger biomass was observed by treatment with purified amylolytic enzymes. Meanwhile, the endo- and exo-chitosanases treatment yielded 54 g of g reducing sugars (equivalent to amino sugars)/ kg of fungal biomass, which can be employed for tailor-made carbohydrate production.
Self-Feeder Driver for Voltage Balance in Series-Connected IGBT Associations
A. F. Guerrero-Guerrero,A. J. Ustariz-Farfan,H. E. Tacca,E. A. Cano-Plata 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.1
The emergence of high voltage conversion applications has resulted in a trend of using semiconductor device seriesassociations. Series associations allow for operation at blocking voltages, which are higher than the nominal voltage for each ofthe semiconductor devices. The main challenge with these topologies is finding a way to guarantee the voltage balance betweendevices in both blocking and switching transients. Most of the methods that have been proposed to mitigate static and dynamicvoltage unbalances result in increased losses within the device. This paper introduces a new series stack topology, where thevoltage unbalances are reduced. This in turn, mitigates the switching losses. The proposed topology consists of a circuit thatensures the soft switching of each device, and one auxiliary circuit that allows for switching energy recovery. The principle forthe topology operation is presented and experimental tests are performed for two modules. The topology performs excellently forswitching transients on each of the devices. The voltage static unbalances were limited to 10%, while the activation/deactivationdelay introduced by the lower module IGBT driver takes place in the dynamic unbalances. Thus, the switching losses are reducedby 40%, when compared to hard switching configurations.
Jordi Cano-Batalla,Jordi Caballé-Serrano,Josep Cabratosa-TermeOscar Figueras-Álvarez,Herminio García-Roncero 대한치과보철학회 2015 The Journal of Advanced Prosthodontics Vol.7 No.2
PURPOSE In this study, a temporal abutment fixation screw, designed to fracture in a controlled way upon application of an occlusal force sufficient to produce critical micromotion was developed. The purpose of the screw was to protect the osseointegration of immediate loaded single implants. MATERIALS AND METHODS Seven different screw prototypes were examined by fixing titanium abutments to 112 Mozo-Grau external hexagon implants (MG Osseous®; Mozo-Grau, S.A., Valladolid, Spain). Fracture strength was tested at 30° in two subgroups per screw: one under dynamic loading and the other without prior dynamic loading. Dynamic loading was performed in a single-axis chewing simulator using 150,000 load cycles at 50 N. After normal distribution of obtained data was verified by Kolmogorov-Smirnov test, fracture resistance between samples submitted and not submitted to dynamic loading was compared by the use of Student's t-test. Comparison of fracture resistance among different screw designs was performed by the use of one-way analysis of variance. Confidence interval was set at 95%. RESULTS Fractures occurred in all screws, allowing easy retrieval. Screw Prototypes 2, 5 and 6 failed during dynamic loading and exhibited statistically significant differences from the other prototypes. CONCLUSION Prototypes 2, 5 and 6 may offer a useful protective mechanism during occlusal overload in immediate loaded implants.
Self-Feeder Driver for Voltage Balance in Series-Connected IGBT Associations
Guerrero-Guerrero, A.F.,Ustariz-Farfan, A.J.,Tacca, H.E.,Cano-Plata, E.A. The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.1
The emergence of high voltage conversion applications has resulted in a trend of using semiconductor device series associations. Series associations allow for operation at blocking voltages, which are higher than the nominal voltage for each of the semiconductor devices. The main challenge with these topologies is finding a way to guarantee the voltage balance between devices in both blocking and switching transients. Most of the methods that have been proposed to mitigate static and dynamic voltage unbalances result in increased losses within the device. This paper introduces a new series stack topology, where the voltage unbalances are reduced. This in turn, mitigates the switching losses. The proposed topology consists of a circuit that ensures the soft switching of each device, and one auxiliary circuit that allows for switching energy recovery. The principle for the topology operation is presented and experimental tests are performed for two modules. The topology performs excellently for switching transients on each of the devices. The voltage static unbalances were limited to 10%, while the activation/deactivation delay introduced by the lower module IGBT driver takes place in the dynamic unbalances. Thus, the switching losses are reduced by 40%, when compared to hard switching configurations.
Anahí Naymé Herrera Cano,María Eugenia Suárez 한국식품연구원 2019 Journal of Ethnic Foods Vol.6 No.-
Algarroba (Prosopis alba) beer, known as aloja de algarroba (abbreviated aloja) in local Spanish, is the ancestral alcoholic beverage par excellence of the Wichís and other indigenous peoples of South American Gran Chaco, but nowadays is in disuse. Mentions on the recipe exist, but they are relatively few, concise and/or partial, and most of them were not registered within ethnobiological studies. The aims of this study were to (a) describe in detail the preparation process of algarroba beer and (b) analyse the process from a holistic approach, integrating Wichí concepts and biological explanations. Any morphological type of Prosopis alba fruits is useful, except those with poor mesocarp. Aloja must be prepared from relative fresh fruits, ground into pieces and not from flour alone. Through the senses, mainly taste and smell, the procedure is followed until optimal fermentation time is reached, which occurs at 24–48 h. When aloja is ready, it tastes tapay (bitter-sour) or nusuy (sour-salty). From the Wichí perspective, fermentation is both a maturation and a cooking process, and it is the “strength” (qahay, qahnayaj) of the pods, an intrinsic property, which allows fermentation to occur, with alcohol production. All interviewees’ remarks about the recipe are also explained by microbiological concepts. Altogether, results expand the knowledge on Wichí ethnobiology and are also useful to other disciplines interested in traditional food systems. Besides, they constitute a contribution to the rescue of the know-how on this traditional beverage for future generations and ultimately to food sovereignty.
Monte Carlo Simulations for the Study of a Moderated Neutron Detector
M. B. Gomez Hornillos,V. Gorlychev,R. Caballero,G. Cortes,A. Poch,C. Pretel,F. Calvino,J. L. Tain,A. Algora,J. Agramunt,D. Cano-Ott,T. Martinez,E. Mendoza,J. Rissanen,J. Aysto,A. Jokinen,T. Eronen,I. 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
This work presents the Monte Carlo simulations performed with the MCNPX and GEANT4 codes for the design of a BEta deLayEd Neutron detector, BELEN-20. This detector will be used for the study of beta delayed neutron emission and consists of a block of polyethylene with dimensions 90 × 90 × 80 cm ^3 and 20 cylindrical ^3He gas counters. The results of these simulations have been validated experimentally with a ^(252)Cf source in the laboratory at UPC, Barcelona. Also the first experiment with this detector has been carried out in November 2009 in JYFL, Finland. In this experiment the neutron emission probability after beta decay of the fission products ^(88)Br, ^(94,95)Rb and ^(138)I has been measured; this data is still under analysis. Simulations with MCNPX and GEANT4 have been performed in order to obtain the efficiency of the BELEN-20 detector for each of the above nuclei using the neutron energy distribution corresponding to each nucleus.
Edith E. Lopéz-Martínez,Jesús A. Claudio-Rizo,Martín Caldera-Villalobos,Juan J. Becerra-Rodríguez,Denis A. Cabrera-Munguía,Lucía F. Cano-Salazar,Rebeca Betancourt-Galindo 한국고분자학회 2022 Macromolecular Research Vol.30 No.6
Novel synthetic strategies to produce biopolymer based hydrogels for biomedical applications are required currently. Collagen hydrogels for wound healing can improve their structural and physicochemical properties by incorporating polysaccharides within the fibrillar matrix. Novel hydrogels were synthesized by semi-interpenetration of guar gum (GG) in a matrix of crosslinked collagen with hydrophilic polyurethane. GG concentrations of 10, 20, 30, and 40 wt% on the semi- IPN matrices were tested. The addition of the polysaccharide accelerates the gelling time of the hydrogels; 30 wt% of GG allows a 68 ± 5% of physicochemical crosslinking, exhibiting a maximum swelling of 3496 ± 89% and both improved mechanical and thermal resistance. The short-range interactions established in these matrices, mainly of the hydrogen bond type, make it possible to delay their hydrolytic and proteolytic degradation. The structure and properties of these hydrogels could have potential application in biomedicine as dressings for chronic wound healing, tailoring the controlled release of drugs with therapeutic interest, cell viability and proliferation, cell signaling, hemocompatibility and antibacterial character.
Fernando Gonzá,lez-Magañ,a,Hé,ctor Omar Malagó,n-Hidalgo,Eugenio Garcí,a-Cano,Roberto Vilchis-Ló,pez,Adriana Fentanes-Vera,Fernan-Alejandra Ayala-Ugalde 대한구강악안면외과학회 2018 대한구강악안면외과학회지 Vol.44 No.1
Objectives: Airway management in patients with panfacial trauma is complicated. In addition to involving facial lesions, such trauma compromises the airway, and the use of intermaxillary fixation makes it difficult to secure ventilation by usual approaches (nasotracheal or endotracheal intubation). Submental airway derivation is an alternative to tracheostomy and nasotracheal intubation, allowing a permeable airway with minimal complications in complex patients. Materials and Methods: This is a descriptive, retrospective study based on a review of medical records of all patients with facial trauma from January 2003 to May 2015. In total, 31 patients with complex factures requiring submental airway derivation were included. No complications such as bleeding, infection, vascular, glandular, or nervous lesions were presented in any of the patients. Results: The use of submental airway derivation is a simple, safe, and easy method to ensure airway management. Moreover, it allows an easier reconstruction. Conclusion: Based on these results, we concluded that, if the relevant steps are followed, the use of submental intubation in the treatment of patients with complex facial trauma is a safe and effective option.
Edith E. Lopéz-Martínez,Jesús A. Claudio-Rizo,Martín Caldera-Villalobos,Juan J. Becerra-Rodríguez,Denis A. Cabrera-Munguía,Lucía F. Cano-Salazar,Rebeca Betancourt-Galindo 한국고분자학회 2022 Macromolecular Research Vol.30 No.6
Determining the controlled release capacity of drugs with therapeutic interest as well as the biocompatibility of hydrogels based on natural and synthetic polymers is of the utmost importance to evaluate their potential performance in regenerative medicine strategies. Novel hydrogels were synthesized by semi-interpenetration of guar gum (GG) in a matrix of crosslinked collagen with hydrophilic polyurethane. GG concentrations of 10, 20, 30 and 40 wt% on the semi-IPN matrices were tested. These hydrogels have excellent in vitro biocompatibility, not demonstrating cytotoxic character for cells important in the healing process such as monocytes and fibroblasts, stimulating their proliferation, as well as evidencing hemocompatibility and antibacterial capacity. Also these matrices can encapsulate and release methylene blue in a controlled manner. The results of the evaluation of human monocyte signaling indicate that the semi-IPN matrix containing 30 wt% of GG allows higher segregation of beta-1 transforming growth factor (β1-TGF), a determinant cytokine in the construction of new tissue, showing that these hydrogels have potential application in biomedicine as dressings for chronic wound healing.
Past, Present and Future of the n_TOF Facility at CERN
E. Chiaveri,S. Andriamonje,M. Calviani,V. Vlachoudis,M. Brugger,P. Cennini,F. Cerutti,M. Chin,A. Ferrari,Y. Kadi,E. Lebbos,R. Losito,C. Guerrero,V. Becares,D. Cano-Ott,M. Fernandez-Ordonez,E. Gonzalez 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
The n_TOF spallation neutron facility is operating at CERN since 2001. Neutrons are produced with a very wide energy range, from thermal up to 1 GeV and with a very high instantaneous flux (10^5n/cm^2/pulse at 200 m from target) thanks to the high intensity (7 × 10^(12) protons/pulse) and low repetition rate of the Proton Synchrotron (PS) which is delivering protons to a lead spallation target. The experimental area is located at 200 m from the target, resulting in a very good energy resolution and beam quality thanks to the adoption of an optimal collimation system. At the end of 2008 the n_TOF facility has resumed operation after a halt of 3 years due to technical issues. This contribution will outline the main physics results obtained by the facility since its inception in 1999, and show the importance of the measured nuclear data in the field of Nuclear Astrophysics and Nuclear Technology. Then it will present the future perspectives of the facility, aiming mainly in the direction of measuring highly radioactive samples, for which the facility has unique capabilities, with a lower background.