http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Zixin Song (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Pectin oligosaccharides improved lipid metabolism in white adipose tissue of high-fat diet fed mice
Zixin Fan,Xuejiao Chen,Tianzhi Liu,Qianhui Yu,Ziqi Song,Fei Wang,Tuoping Li 한국식품과학회 2022 Food Science and Biotechnology Vol.31 No.9
Impacts of pectin oligosaccharide (POS) got from hawthorn fruitage on adiponectin signaling pathway and white adipose metabolism in mice fed with high-fat control. The results showed that POS significantly inhibited the levels of inflammatory cytokines TNF-α and IL-6, and down-regulated expression of CD68. POS dramatically reduced gene expression contents of fatty acid composite concerning enzymes ACC and FAS, as well as TG synthesis-related enzymes SCD-1 and DGAT1 as compared to a high-fat group (HFC). POS dramatically increased expression levels of oxidation-related enzymes of fatty acid ACO, CPT-1, and TG deposition-related enzymes ATGL and HSL as contrast to the high-fat control group. In addition, POS activated adiponectin-mediated AdipoR1/AMPK/PPARα signaling path by upregulating expression levels of AdipoR1, AMPK and PPARα. The results demonstrated that POS can improve lipid metabolism of adipose tissue, and contribute to the creation of functional foods to prevent and treat lipid metabolism disorders.
-
Analysis of Strong Stress Concentrations of Key Joints for Super-Spanned Steel Truss Bridges
Cong Li,Zixin Song,Guanghui Xia,Xiaofang Kang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.7
In this paper, the strategy of three scales was proposed to analyse strong stress distributions of key joints during the incremental launching construction. Firstly, the internal forces and reaction forces were obtained by the finite element method (FEM). Secondly, some key joints were separated from the whole structure. The displacements and boundary conditions of the separated joint were taken from the results of the FEM. Then the stress distributions of the separated joint were successfully obtained by using the FEM. Thirdly, the local stress concentration areas were separated from the key joint structure. The high stress distributions of the local stress concentration region were successfully obtained by using the extended boundary element method (XBEM). On the other hand, the stress of some joints were measured through mechanical test on the construction site. And calculation results of the FEM and XBEM were in good agreement with test results. A multi-scale method is developed to obtain the strong stress concentration during the construction of the super-spanned steel truss bridge accurately, which enables the safety of the construction. In addition, the present method can be further used to guide the design of super-tall building, super-spanned bridge, etc.
-
Baisong Zhao,Xingrong Song,Yongying Pan,Zixin Wang,Haiping Xu 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.1
Purpose: To investigate the effects of hyperbaric oxygen (HBO) pretreatment on cognitive decline and neuronal damage in an Alzheimer’sdisease (AD) rat model. Materials and Methods: Rats were divided into three groups: normal saline (NS), AD, and HBO+AD. In the AD group, amyloid β peptide (Aβ)1-40 was injected into the hippocampal CA1 region of the brain. NS rats received NS injection. In the HBO+AD group, rats received 5 days of daily HBO therapy following Aβ1-40 injection. Learning and memory capabilities were examined using the Morris water maze task. Neuronal damage and astrocyte activation were evaluated by hematoxylin-eosin staining and immunohistochemistry,respectively. Dendritic spine density was determined by Golgi-Cox staining. Tumor necrosis factor-α, interleukin-1β, and interleukin-10 production was assessed by enzyme-linked immunosorbent assay. Neuron apoptosis was evaluated by terminal deoxynucleotidyl transferase dUTP nick end labeling. Protein expression was examined by western blotting. Results: Learning and memory dysfunction was ameliorated in the HBO+AD group, as shown by significantly lower swimming distances and escape latency, compared to the AD group. Lower rates of neuronal damage, astrocyte activation, dendritic spine loss, and hippocampal neuron apoptosis were seen in the HBO+AD than in the AD group. A lower rate of hippocampal p38 mitogen-activated protein kinase (MAPK) phosphorylation was observed in the HBO+AD than in the AD group. Conclusion: HBO pretreatment improves cognition and reduces hippocampal damage via p38 MAPK in AD rats.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
