Design and Prediction of Three Dimensional Flows in a Low Speed Highly Loaded Axial Flow Fan

Xuejiao Liu,Liu Chen,Ren Dai,Ailing Yang 한국유체기계학회 2013 International journal of fluid machinery and syste Vol.6 No.2

This paper describes the design to increase the blade loading factor of a low speed axial flow fan from normal 0.42 to highly loaded 0.55. A three-dimensional viscous solver is used to model the flows in the highly-loaded and normal loaded stages over its operation range. At the design point operation the static pressure rise can be increased by 20 percent with a deficit of efficiency by 0.3 percent. In the highly loaded fan stage, the rotor hub flow stalls, and separation vortex extends over the rotor hub region. The backflow, which occurs along the stator hub-suction surface, changes the exit flow from the prescribed axial direction. Results in this paper confirm that the limitation of the two dimensional diffusion does not affect primarily on the fan's performance. Highly loaded fan may have actually better performance than its two dimensional design. Three dimensional designing approaches may lead to better highly loaded fan with controlled rotor hub stall.

Computer-aided diagnosis system based on multi-scale feature fusion for screening large-scale gastrointestinal diseases

Pang Xuejiao,Zhao Zijian,Wu Yanbing,Chen Yong,Liu Jin 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.1

For endoscopists, large-scale screening of gastrointestinal (GI) diseases is arduous and time-consuming. While their workload and human factor-induced errors can be reduced by computer-aided diagnosis (CAD) systems, the existing ones mainly focus on a limited number of lesions or specific organs, making them unsuitable for diagnosing various GI diseases in large-scale disease screening. This paper proposes a transformer and convolutional neural network-based CAD system (called TransMSF) to assist endoscopists in diagnosing multiple GI diseases. This system constructs two feature extraction paths with different coding methods to obtain the lesions’ global and local information. In addition, downsampling is implemented in transformer to get global information of different scales, further enriching the feature representation and reducing the amount of computation and memory occupation. Moreover, a channel and spatial attention module with fewer parameters was successfully designed to pay more attention to the target and reduce the loss of important information during spatial dimension transformation. Finally, the extracted feature information is fused through the feature fusion module and then input into the linear classifier for disease diagnosis. The proposed system outperformed that of other state-of-the-art models on two datasets, reaching a 98.41% precision, a 98.15% recall, a 98.13% accuracy, and a 98.28% F1 score on the in-house GI dataset versus a 95.88% precision, a 95.88% recall, a 98.97% accuracy, and a 95.88% F1 score on the public Kvasir dataset. Moreover, TransMSF’s performance was superior to that of seasoned endoscopists. The above results prove that the proposed system is instrumental in diagnosing GI diseases in large-scale disease screening. It can also be used as a training tool for junior endoscopists to improve their professional skills by rendering helpful suggestions.

Design and Prediction of Three Dimensional Flows in a Low Speed Highly Loaded Axial Flow Fan

Liu, Xuejiao,Chen, Liu,Dai, Ren,Yang, Ailing Korean Society for Fluid machinery 2013 International journal of fluid machinery and syste Vol.6 No.2

This paper describes the design to increase the blade loading factor of a low speed axial flow fan from normal 0.42 to highly loaded 0.55. A three-dimensional viscous solver is used to model the flows in the highly-loaded and normal loaded stages over its operation range. At the design point operation the static pressure rise can be increased by 20 percent with a deficit of efficiency by 0.3 percent. In the highly loaded fan stage, the rotor hub flow stalls, and separation vortex extends over the rotor hub region. The backflow, which occurs along the stator hub-suction surface, changes the exit flow from the prescribed axial direction. Results in this paper confirm that the limitation of the two dimensional diffusion does not affect primarily on the fan's performance. Highly loaded fan may have actually better performance than its two dimensional design. Three dimensional designing approaches may lead to better highly loaded fan with controlled rotor hub stall.

Pectin oligosaccharides improved lipid metabolism in white adipose tissue of high-fat diet fed mice

Zixin Fan,Xuejiao Chen,Tianzhi Liu,Qianhui Yu,Ziqi Song,Fei Wang,Tuoping Li 한국식품과학회 2022 Food Science and Biotechnology Vol.31 No.9

Impacts of pectin oligosaccharide (POS) got from hawthorn fruitage on adiponectin signaling pathway and white adipose metabolism in mice fed with high-fat control. The results showed that POS significantly inhibited the levels of inflammatory cytokines TNF-α and IL-6, and down-regulated expression of CD68. POS dramatically reduced gene expression contents of fatty acid composite concerning enzymes ACC and FAS, as well as TG synthesis-related enzymes SCD-1 and DGAT1 as compared to a high-fat group (HFC). POS dramatically increased expression levels of oxidation-related enzymes of fatty acid ACO, CPT-1, and TG deposition-related enzymes ATGL and HSL as contrast to the high-fat control group. In addition, POS activated adiponectin-mediated AdipoR1/AMPK/PPARα signaling path by upregulating expression levels of AdipoR1, AMPK and PPARα. The results demonstrated that POS can improve lipid metabolism of adipose tissue, and contribute to the creation of functional foods to prevent and treat lipid metabolism disorders.

A Bio-memristor with Overwhelming Capacitance Effect

Shuangsuo Mao,Xuejiao Zhang,Bai Sun,Bing Li,Tian Yu,Yuanzheng Chen,Yong Zhao 대한금속·재료학회 2019 ELECTRONIC MATERIALS LETTERS Vol.15 No.5

A bio-memristor, which was prepared using the bio-materials as basic components, has being become the focus of researchowing to the potential application as medical diagnosis in biomedical field. Herein, an environmentally-friendly and sustainablebio-memristor device with Ag/walnut skin (WS)/ITO structure was fabricated, in which an obvious and reliablyrepeated rectangular current–voltage characteristic curve is observed. Our result shows that the WS, an useless bio-material,can be used to fabricate electronic devices after proper processing. Finally, the memory mechanism based on the conductivefilament mode associated the capacitance effect is ascribed. This work has opened a new way to exploit the next generationbio-electronic device with advantages of environmentally-friendly, sustainable and pollution-free.

Low-temperature solution selective growth of zinc oxide nanorods on different substrates

Jian Zhang,Lijuan Wan,Xuejiao Chen,Chunran Liu,Huina Hou 한양대학교 세라믹연구소 2010 Journal of Ceramic Processing Research Vol.11 No.3

In this paper, regular ZnO nanorods with excellent reproducibility were grown by a simple solution method at low temperature. The growth parameters, which can affect the ZnO nanostructures were studied, including the substrate types, the growth temperature, the growth time and the concentration of the solution. Among these conditions, the influence of different substrates on the resulting nanostructures was investicated carefully. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) were used to characterize the morphology and microstructure of the as-grown ZnO nanorods. It is concluded that the substrates can affect the ZnO growth remarkably and the selective growth of ZnO is possible through the choice of the substrates.

Transcriptome Analysis Reveals Molecular Mechanisms Underlying Methyl Jasmonate-mediated Biosynthesis of Protopanaxadiol-type Saponins in Panax notoginseng Leaves

Li Ying,Lin Yuan,Jia Bing,Chen Geng,Shi Huineng,Xu Rui,Li Xuejiao,Tang Junrong,Tang Qingyan,Zhang Guanghui,Yang Jianli,Fan Wei,Yang Shengchao 한국식물학회 2022 Journal of Plant Biology Vol.65 No.1

Methyl jasmonate (MeJA) has been widely used to improve the biosynthesis of secondary metabolites such as triterpenoid saponins in medicinal plants. However, the underlying molecular mechanisms remain poorly understood. Differing from roots that accumulate protopanaxatriol-type saponins, Panax notoginseng leaves with a lower biomass mainly contain protopanaxadiol (PPD)-type saponins. Therefore, it is interesting to explore whether MeJA can activate the biosynthesis of PPD-type saponins in P. notoginseng leaves. In this study, we found MeJA could effectively induce the accumulation of PPD-type saponins, including ginsenoside Rb1, Rc, Rb2, Rb3 and notoginsenoside Fa, Fe in P. notoginseng leaves based on a newly established high-performance liquid chromatography method. Transcriptome analysis showed that differentially expressed genes (DEGs) induced by MeJA were mainly enriched in “terpenoid backbone biosynthesis”, “biosynthesis of unsaturated fatty acids”, “sesquiterpenoid and triterpenoid biosynthesis”, “fatty acid metabolism”, and “phenylpropanoid biosynthesis”. Furthermore, the expression profile and quantitative real-time PCR analysis of DEGs showed that MeJA could positively induce the molecular response of endogenous jasmonic acid (JA) signaling pathway, and increased PPD-type saponins mediated by MeJA in P. notoginseng leaves may be related to the high expression of FPS, SS, SE, DS and UGTs, and the low expression of CYP716A53v2 and β-AS. The results provide a molecular understanding for MeJA-elicited biosynthesis of triterpenoid saponins and facilitate the further characterization of the genes responsible for biosynthesis of PPD-type saponins in P. notoginseng leaves.

Towards efficient sharing of encrypted data in cloud-based mobile social network

( Xin Sun ),( Yiyang Yao ),( Yingjie Xia ),( Xuejiao Liu ),( Jian Chen ),( Zhiqiang Wang ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.4

Mobile social network is becoming more and more popular with respect to the development and popularity of mobile devices and interpersonal sociality. As the amount of social data increases in a great deal and cloud computing techniques become developed, the architecture of mobile social network is evolved into cloud-based that mobile clients send data to the cloud and make data accessible from clients. The data in the cloud should be stored in a secure fashion to protect user privacy and restrict data sharing defined by users. Ciphertext-policy attribute-based encryption (CP-ABE) is currently considered to be a promising security solution for cloud-based mobile social network to encrypt the sensitive data. However, its ciphertext size and decryption time grow linearly with the attribute numbers in the access structure. In order to reduce the computing overhead held by the mobile devices, in this paper we propose a new Outsourcing decryption and Match-then-decrypt CP-ABE algorithm (OM-CP-ABE) which firstly outsources the computation-intensive bilinear pairing operations to a proxy, and secondly performs the decryption test on the attributes set matching access policy in ciphertexts. The experimental performance assessments show the security strength and efficiency of the proposed solution in terms of computation, communication, and storage. Also, our construction is proven to be replayable choosen-ciphertext attacks (RCCA) secure based on the decisional bilinear Diffie-Hellman (DBDH) assumption in the standard model.

Inhibition of chromosomal region maintenance 1 suppresses the migration and invasion of glioma cells via inactivation of the STAT3/MMP2 signaling pathway

Qianqian Shan,Shengsheng Li,Qiyu Cao,Chenglong Yue,Mingshan Niu,Xiangyu Chen,Lin Shi,Huan Li,Shangfeng Gao,Jun Liang,Rutong Yu,Xuejiao Liu 대한생리학회-대한약리학회 2020 The Korean Journal of Physiology & Pharmacology Vol.24 No.3

Chromosomal region maintenance 1 (CRM1) is associated with an adverse prognosis in glioma. We previously reported that CRM1 inhibition suppressed glioma cell proliferation both in vitro and in vivo. In this study, we investigated the role of CRM1 in the migration and invasion of glioma cells. S109, a novel reversible selective inhibitor of CRM1, was used to treat Human glioma U87 and U251 cells. Cell migration and invasion were evaluated by wound-healing and transwell invasion assays. The results showed that S109 significantly inhibited the migration and invasion of U87 and U251 cells. However, mutation of Cys528 in CRM1 abolished the inhibitory activity of S109 in glioma cells. Furthermore, we found that S109 treatment decreased the expression level and activity of MMP2 and reduced the level of phosphorylated STAT3 but not total STAT3. Therefore, the inhibition of migration and invasion induced by S109 may be associated with the downregulation of MMP2 activity and expression, and inactivation of the STAT3 signaling pathway. These results support our previous conclusion that inhibition of CRM1 is an attractive strategy for the treatment of glioma.

Effect of Thermal Treatment on the Texture and Microstructure of Abalone Muscle (Haliotis discus)

Beiwei Zhu,Xiuping Dong,Liming Sun,Guihua Xiao,Xuejiao Chen,Yoshiyuki Murata,Chenxu Yu 한국식품과학회 2011 Food Science and Biotechnology Vol.20 No.6

The texture and microstructure of edible abalone meats were studied during heat treatments from 50to 100^oC for 60 min. No increase in extractable soluble collagen content was observed below 80^oC, but a 9-fold increase was observed at 100^oC. SDS-PAGE showed that extractable myosin heavy chains and paramyosin contents reduced significantly at 80^oC, and disappeared completely at 100^oC. The shear force increased slowly from 50 to 70^oC, but relaxed back to the initial level at 100^oC. Rapid reduction of hardness was observed at 50^oC, minimum hardness was obtained at 100^oC. Springness, cohesiveness,chewiness, and resilience were enhanced to maximum levels at 70, 90, 70, and 90^oC, respectively. Optical micrographs and transmission electron microscope showed a significant increase of intermyofibrillar gaps at 90^oC and broken fibers at 100^oC. Results suggested that 80^oC might be a suitable temperature to produce ready-to-eat abalone products.