Macro-/micro-environment-sensitive chemosensing and biological imaging

Yang, Zhigang,Cao, Jianfang,He, Yanxia,Yang, Jung Ho,Kim, Taeyoung,Peng, Xiaojun,Kim, Jong Seung The Royal Society of Chemistry 2014 Chemical Society reviews Vol.43 No.13

<P>Environment-related parameters, including viscosity, polarity, temperature, hypoxia, and pH, play pivotal roles in controlling the physical or chemical behaviors of local molecules. In particular, in a biological environment, such factors predominantly determine the biological properties of the local environment or reflect corresponding status alterations. Abnormal changes in these factors would cause cellular malfunction or become a hallmark of the occurrence of severe diseases. Therefore, in recent years, they have increasingly attracted research interest from the fields of chemistry and biological chemistry. With the emergence of fluorescence sensing and imaging technology, several fluorescent chemosensors have been designed to respond to such parameters and to further map their distributions and variations <I>in vitro</I>/<I>in vivo</I>. In this work, we have reviewed a number of various environment-responsive chemosensors related to fluorescent recognition of viscosity, polarity, temperature, hypoxia, and pH that have been reported thus far.</P> <P>Graphic Abstract</P><P>We have summarized the research progress on fluorescent sensors responsive to environmental factors, including local viscosity, polarity, temperature, hypoxia and pH. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4cs00051j'> </P>

Longitudinal static stability requirements for wing in ground effect vehicle

Yang, Wei,Yang, Zhigang,Collu, Maurizio The Society of Naval Architects of Korea 2015 International Journal of Naval Architecture and Oc Vol.7 No.2

The issue of the longitudinal stability of a WIG vehicle has been a very critical design factor since the first experimental WIG vehicle has been built. A series of studies had been performed and focused on the longitudinal stability analysis. However, most studies focused on the longitudinal stability of WIG vehicle in cruise phase, and less is available on the longitudinal static stability requirement of WIG vehicle when hydrodynamics are considered: WIG vehicle usually take off from water. The present work focuses on stability requirement for longitudinal motion from taking off to landing. The model of dynamics for a WIG vehicle was developed taking into account the aerodynamic, hydrostatic and hydrodynamic forces, and then was analyzed. Following with the longitudinal static stability analysis, effect of hydrofoil was discussed. Locations of CG, aerodynamic center in pitch, aerodynamic center in height and hydrodynamic center in heave were illustrated for a stabilized WIG vehicle. The present work will further improve the longitudinal static stability theory for WIG vehicle.

Two-dimensional multiple-snapshot grid-free compressive beamforming

Yang, Yang,Chu, Zhigang,Ping, Guoli Elsevier 2019 Mechanical systems and signal processing Vol.124 No.-

<P><B>Abstract</B></P> <P>Compressive beamforming with planar microphone arrays can effectively achieve the two-dimensional direction-of-arrival (DOA) estimation and strength quantification of acoustic sources. This paper focuses on developing a multiple-snapshot grid-free method and comparing it against the existing grid-based and single-snapshot grid-free ones. The minimization of the atomic norm of multiple-snapshot microphone pressure induced by acoustic sources and the matrix pencil and pairing method are utilized jointly. The former is utilized to denoise the measured pressure and therefore obtain the pressure from acoustic sources. The latter is utilized to estimate DOAs and quantify strengths. Both simulations and experiments demonstrate the advantages of the developed method. For sources that are active across multiple snapshots, it can overcome the basis mismatch conundrum of the grid-based compressive beamforming. When the sources are uncorrelated or partially correlated in both spatial and temporal dimensions, it outperforms the single-snapshot grid-free compressive beamforming in terms of denoising, DOA estimation and strength quantification accuracy and resolution. These advantages stand up whether a standard uniform rectangular array or a non-uniform array constituted by a small number of microphones is utilized.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A two-dimensional multiple-snapshot grid-free compressive beamforming method is proposed. </LI> <LI> It can overcome the basis mismatch conundrum of the grid-based method. </LI> <LI> It enjoys obvious advantages over the single-snapshot grid-free method. </LI> </UL> </P>

A Nile Red/BODIPY-based bimodal probe sensitive to changes in the micropolarity and microviscosity of the endoplasmic reticulum

Yang, Zhigang,He, Yanxia,Lee, Jae Hong,Chae, Weon-Sik,Ren, Wen Xiu,Lee, Joung Hae,Kang, Chulhun,Kim, Jong Seung The Royal Society of Chemistry 2014 Chemical communications Vol.50 No.79

<P>We herein report a fluorescent bimodal probe (<B>1</B>) capable of determining ER viscosity and polarity changes using FLIM and fluorescence ratiometry, respectively; during ER stress caused by tunicamycin, the viscosity was increased from <I>ca.</I> 129.5 to 182.0 cP and the polarity of the ER (dielectric constant, <I>ϵ</I>) enhanced from 18.5 to 21.1.</P> <P>Graphic Abstract</P><P>A fluorescent bimodal chemosensor was developed to determine ER viscosity and polarity changes during ER stress caused by tunicamycin. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4cc04915b'> </P>

Super-resolution fluorescent materials: an insight into design and bioimaging applications

Yang, Zhigang,Sharma, Amit,Qi, Jing,Peng, Xiao,Lee, Dong Yeop,Hu, Rui,Lin, Danying,Qu, Junle,Kim, Jong Seung The Royal Society of Chemistry 2016 Chemical Society reviews Vol.45 No.17

<P>Living organisms are generally composed of complex cellular processes which persist only within their native environments. To enhance our understanding of the biological processes lying within complex milieus, various techniques have been developed. Specifically, the emergence of super-resolution microscopy has generated a renaissance in cell biology by redefining the existing dogma towards nanoscale cell dynamics, single synaptic vesicles, and other complex bioprocesses by overcoming the diffraction-imposed resolution barrier that is associated with conventional microscopy techniques. Besides the typical technical reliance on the optical framework and computational algorithm, super-resolution imaging microscopy resorts largely to fluorescent materials with special photophysical properties, including fluorescent proteins, organic fluorophores and nanomaterials. In this tutorial review article, with the emphasis on cell biology, we summarize the recent developments in fluorescent materials being utilized in various super-resolution techniques with successful integration into bio-imaging applications. Fluorescent proteins (FP) applied in super-resolution microscopy will not be covered herein as it has already been well summarized; additionally, we demonstrate the breadth of opportunities offered from a future perspective.</P>

Feasibility analysis of bone density evaluation with Hounsfield unit value after fibula flap reconstruction of jaw defect

Yihui Yang,Yifan Kang,Yifan Yang,Mengkun Ding,Xiaofeng Shan,Zhigang Cai 대한악안면성형재건외과학회 2023 Maxillofacial Plastic Reconstructive Surgery Vol.45 No.-

Background Implant-supported dentures have become an essential means of restoring occlusal function after jaw reconstruction. Bone mineral density (BMD) may influence the success rate of implant denture restorations. This study aimed to explore whether the Hounsfield unit (HU) value can be used to monitor the changing trend of fibular BMD after jaw reconstruction. Results A total of 54 patients who underwent maxillar/mandibular reconstruction with a fibula flap were included in this study. There was a significant correlation between the HU value and BMD at 1 week, 3 months, and 6 months after surgery, and both were significantly correlated with follow-up time. The difference between each pair of absorption rates (DAR) was less than 10% in 66.7% and 75.9% of patients at 3 and 6 months; however, the DAR was more than 20% in 12% and 13.8% of patients at 3 and 6 months, respectively. Conclusions There is a significant correlation between HU value and BMD. The HU value can be used to roughly reflect the fibular BMD changing trend in a group of patients as opposed to an individual, and the HU value is not equivalent to BMD. Trial registration ChiCTR, ChiCTR2300069661, retrospectively registered on 22 March 2023. Retrospectively registered, https:// www. chictr. org. cn/ showp roj. html? proj= 188953.

Longitudinal static stability requirements for wing in ground effect vehicle

Wei Yang,Zhigang Yang,Maurizio Collu 대한조선학회 2015 International Journal of Naval Architecture and Oc Vol.7 No.2

The issue of the longitudinal stability of a WIG vehicle has been a very critical design factor since the first experimental WIG vehicle has been built. A series of studies had been performed and focused on the longitudinal stability analysis. However, most studies focused on the longitudinal stability of WIG vehicle in cruise phase, and less is available on the longitudinal static stability requirement of WIG vehicle when hydrodynamics are considered: WIG vehicle usually take off from water. The present work focuses on stability requirement for longitudinal motion from taking off to landing. The model of dynamics for a WIG vehicle was developed taking into account the aerodynamic, hydrostatic and hydrodynamic forces, and then was analyzed. Following with the longitudinal static stability analysis, effect of hydrofoil was discussed. Locations of CG, aerodynamic center in pitch, aerodynamic center in height and hydrodynamic center in heave were illustrated for a stabilized WIG vehicle. The present work will further improve the longitudinal static stability theory for WIG vehicle.

Preparation of magnetic carbon spheres derived form 8-quinoliolato Fe (III) complexe and its application in water treatment

Zhigang Jia,Lulu Yang,Jianhong Liu,Qiuze Wang,Rongsun Zhu 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.21 No.1

Magnetic carbon spheres have been successfully prepared by the synchronous carbonation and activationof the 8-quinoliolato Fe(III) complexe with sphere morphology, which has been synthesized bysolovthermal method. The obtained composite possesses relatively even pore diameter of 3.8 nm, highsurface area of 335.59m2/g with 52.67 wt.% Fe3O4 coated, and a saturation magnetization (Ms) of35.27 emu/g. Dye separationperformance of the magnetic carbon spheres is investigated using methyleneorange and methylene blue as modle. The resluts show that the maxium adsorption capacity formethylene orange and methylene blue is 128.70mgg 1 and 151.29mgg 1, respectively, and the processcan rapidly reach adsorption equilibrium within 5 min, which is important for the application of the aspreparedmagnetic carbon spheres.

Hydrothermal Synthesis of Cubic Mesocrystal CeO₂ for Visible Photocatalytic Degradation of Rhodamine B

Yang, Hexiang,Zhou, Mengkai,Meng, Zeda,Zhu, Lei,Chen, Zhigang,Oh, Won-Chun Materials Research Society of Korea 2015 한국재료학회지 Vol.25 No.3

Cubic mesocrystal $CeO_2$ was synthesized via a hydrothermal method with glutamic acid ($C_5H_9NO_4$) as a template. The XRD pattern of a calcined sample shows the face-centered cubic fluorite structure of ceria. Transmission electron microscopy (TEM) and the selected-area electron diffraction (SAED) pattern revealed that the submicron cubic mesocrystals were composed of many small crystals attached to each other with the same orientation. The UV-visible adsorption spectrum exhibited the red-shift phenomenon of mesocrystal $CeO_2$ compared to commercial $CeO_2$ particles; thus, the prepared materials show tremendous potential to degrade organic dyes under visible light illumination. With a concentration of a rhodamine B solution of 20 mg/L and a catalyst amount of 0.1 g/L, the reaction showed higher photocatalytic performance following irradiation with a xenon lamp (${\geq}380nm$). The decoloring rate can exceed 100% after 300 min.

An Experimental Study of the Hyper-parameters Distribution Region and Its Optimization Method for Support Vector Machine with Gaussian Kernel

Zhigang Yan,Yuanxuan Yang,Yunjing Ding 보안공학연구지원센터(IJSIP) 2013 International Journal of Signal Processing, Image Vol.6 No.5