녹음 구어 제시가 중도정신지체 성인여성의 목욕 능력 개선에 미치는 효과

鄭如意,陳明聰,陳政見 대구대학교 특수교육재활과학연구소 2006 再活科學硏究 Vol.24 No.2

1. This study aimed to explore the effect of recorded auditory prompts on helping an adult with profound mental retardation to take bath independently. 「A-B-C-A-C」design, a kind of single-subject experiment was adopted. Three phases, baseline phase, intervention phase(B): auditory prompt, and intervention phase(C): recorded auditory prompt were included. A female with profound mental retardation participated in the experiment. It took over seven months to finishing the intervention. The results of the experiment indicated that auditory prompts, whether human auditory prompt or recorded prompt, could help the client to take bath more independently. The families of the client also regarded recorded auditory prompt was a feasible solution. Based on the result, there were some suggestions for the further research. 본 연구의 목적은 녹음 구어 제시를 이용해서 극 중도 지능장애 성인 여성 스스로 목욕 동작을 완성 할 수 있도록 도와주는 효과에 대한 연구입니다. 본 연구에 사용하는 연구법은 ⌜A-B-A-C-A-C⌟역 설계이다. 기선기의(A)개입一(B)인공구어제시 개입二(C)녹음 구어 제시로 나누어졌다. 실험기간은 모두 7개월 반이었다. 연구결과는 피 실험자가 스스로 목욕할 때와 비교했을 때 인공구어 제시와 녹음구어 제시는 모두 피 실험자가 목욕 동작을 완성 하는 데에 효과가 있는 것으로 나타났다. 이 외에도 녹음 구어 제시는 피 실험자 가족들도 받아들일 수 있다. 본 연구 결과에 근거해서 연구자들은 미래 응용과 연구에 대한 건의도 제출하였다.

Letters to the Editor : Decreased Serum Level of Interferon-γ in Patients with Pityriasis Rosea

( Ming Zeng ),( Shi Xiang Zhao ),( Ling Hua Liu ),( Xian Bo Zuo ),( Xiao Dong Zheng ),( Tao Li ),( Min Zhang ),( Pei Guang Wang ),( Sen Yang ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.4

A New Stilbene Glucoside from the Roots of Polygonum multiflorum Thunb.

Ming-Lu Xu,Ming Shan Zheng,Yeon-Kyong Lee,문동철,Chong-Soon Lee,우미희,정병선,Eung Seok Lee,장영동,장현욱,이승호,손종근 대한약학회 2006 Archives of Pharmacal Research Vol.29 No.11

One new stilbene glucoside (6), along with five known compounds (1-5), were isolated from the roots of Polygonum multiflorum Thumb., and their chemical structures established based on physicochemical and spectroscopic data. Of the compounds, compound 3 showed DNA topoisomerase I and II inhibitory activities.

Chemical Constituents of Melandrium firmum Rohrbach and Their Anti-Inflammatory Activity

Ming Shan Zheng,Do Hoon Kim,Nam Kyung Hwang,Tae Chul Moon,Jong Keun Son,장현욱 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.3

In our ongoing search for anti-inflammatory agents originating from Korean medicinal plants, we found that the hexane and BuOH fractions of the MeOH extract from the whole plants of Melandrium firmum Rohrbach inhibited 5-lipoxygenase (5-LOX) activity. By activity-guided fractionation, eleven compounds, α-spinaterol (1), ursolic acid (2), ergosterol peroxide (3), α- spinaterol glucoside (4), 2-methoxy-9-β-D-ribofuranosyl purine (5), aristeromycin (6), ecdysteron (7), polypodoaurein (8), (-)-bornesitol (9), mannitol (10) and cytisoside (11) were isolated from the hexane and BuOH fractions using column chromatography. Compounds 2, 5, 6, 8, 9, 10 and 11 were isolated for the first time from this plant. Compounds 1, 3, 4 and 7 inhibited 5- LOX activity with IC50 values of 21.04 µM, 42.30 µM, 32.82 µM, and 17.18 µM, respectively.

The binder effect on an oxide-based anode in lithium and sodium-ion battery applications: the fastest way to ultrahigh performance

Ming, Jun,Ming, Hai,Kwak, Won-Jin,Shin, Changdae,Zheng, Junwei,Sun, Yang-Kook The Royal Society of Chemistry 2014 Chemical communications Vol.50 No.87

<P>A positive effect of the polyacrylic acid (PAA)–carboxymethyl cellulose (CMC) binder to enhance the performance of an oxide-based anode was reported in batteries. A series of super high capacity and cycling ability oxide powders rarely achieved before was obtained, particularly most of them without any specific carbon modification and/or morphology control.</P> <P>Graphic Abstract</P><P>A positive effect of the polyacrylic acid–carboxymethyl cellulose binder to enhance the performance of an oxide-based anode was reported in batteries. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4cc02657h'> </P>

Prevalence of Allergic Rhinitis Among Adults in Urban and Rural Areas of China: A Population-Based Cross-Sectional Survey

Ming Zheng,Xiangdong Wang,Mingyu Bo,Kuiji Wang,Yan Zhao,Fei He,Feifei Cao,Luo Zhang,Claus Bachert 대한천식알레르기학회 2015 Allergy, Asthma & Immunology Research Vol.7 No.2

Purpose: The aim of the present study was to compare the prevalence of self-reported and confirmable allergic rhinitis (AR) with positive skin pricktest (SPT) results among adults living in urban and rural areas of China. Methods: Adults from a community in Beijing and a village in Baoding wereselected as representative urban and rural dwellers, respectively. All eligible residents were enrolled from the population register and received aface-to-face interview using modified validated questionnaires. Equal sets of randomly selected self-reporting AR-positive and AR-negative participantswho responded to the questionnaires were also investigated using skin prick tests. Results: A total of 803 participants in the rural area and atotal of 1,499 participants in the urban area completed the questionnaires, with response rates being 75.9% and 81.5% respectively. The prevalenceof self-reported AR of the rural area (19.1%) was significantly higher than that of the urban area (13.5%). The elementary school of educational levelincreased the risk of having AR (adjusted OR=2.198, 95% CI=1.072-2.236) .The positive SPT rates among subjects with self-reported AR in therural and urban areas were 32.5% and 53.3%, respectively; the confirmable AR prevalence of 6.2% and 7.2% among the rural and urban adults, respectively. Conclusions: The prevalence of confirmable AR is similar between rural and urban areas in China, although there is a higher prevalenceof self-reported AR in the former. Purpose: The aim of the present study was to compare the prevalence of self-reported and confirmable allergic rhinitis (AR) with positive skin prick test (SPT) results among adults living in urban and rural areas of China. Methods: Adults from a community in Beijing and a village in Baoding were selected as representative urban and rural dwellers, respectively. All eligible residents were enrolled from the population register and received a face-to-face interview using modified validated questionnaires. Equal sets of randomly selected self-reporting AR-positive and AR-negative participants who responded to the questionnaires were also investigated using skin prick tests. Results: A total of 803 participants in the rural area and a total of 1,499 participants in the urban area completed the questionnaires, with response rates being 75.9% and 81.5% respectively. The prevalence of self-reported AR of the rural area (19.1%) was significantly higher than that of the urban area (13.5%). The elementary school of educational level increased the risk of having AR (adjusted OR=2.198, 95% CI=1.072-2.236) .The positive SPT rates among subjects with self-reported AR in the rural and urban areas were 32.5% and 53.3%, respectively; the confirmable AR prevalence of 6.2% and 7.2% among the rural and urban adults, respectively. Conclusions: The prevalence of confirmable AR is similar between rural and urban areas in China, although there is a higher prevalence of self-reported AR in the former.

Autonomous Robot Driving Decision Strategy Following Road Signs And Traffic Rules

Zheng-Hao Chong,Ling Yee,Albert Causo,I-Ming Chen 제어로봇시스템학회 2016 제어로봇시스템학회 국제학술대회 논문집 Vol.2016 No.10

Autonomous robot driving decision strategy following road signs and traffic rules is described using simulation with a Turtlebot [1]. A fully autonomous robot driving strategy is presented, which follows human level logic in decision making. A vision-based autonomous vehicles navigation system for road vehicles includes three main parts: 1) road and traffic signs detection; 2) vehicle movement guidance system; and 3) decision making following human level logic. The first two modules have been studied independently for many years and obtained many good results using different solutions, but there is little research in fully integrated system with high level decision making to achieve fully autonomous robot navigation following road signs. It is valuable to study and apply this concept into a real system. A simulation world is built according to real environment scenario proving the concept of study.

Nonlinear-Dynamic-Analysis Based Fuzzy PID Control Approach for Complex Hydraulic Driving Process

Zheng-Qiang Zhu,Xin-Jiang Lu,Jie Lei,Ming-Hui Huang 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.7

The strong nonlinearity of the hydraulic driving process for forging makes it difficult to achieve accurate control. In this paper, we propose a nonlinear-dynamic-analysis based Fuzzy PID control approach for this complex process. Unlike the existing control methods that are designed specifically for a given work piece, this proposed control method can be effectively used in the forging of different work pieces. A model of the closed-loop forging system is first derived and a solving method is then developed in order to find the model solution. Using this model solution, the dynamics of the closed-loop forging system is further estimated and the conditions for stability, vibration, and creep, as well as the relationships between the controller parameters and the constraints are also derived. These derived dynamic characteristics, conditions and relationships for different work pieces are further integrated and used to design the controller. Through the use of experiments and simulations on a practical forging system, the effectiveness of all of these analytical results and the designed controller is finally demonstrated.

Inhibition of DNA Topoisomerases I and II and Cytotoxicity of Compounds from Ulmus davidiana var. japonica

Zheng, Ming-Shan,Lee, Yeun-Kyung,Li, Ying,HwangBo, Kyoung,Lee, Chong-Soon,Kim, Jae-Ryong,Lee, Sunny Kyung-Seon,Chang, Hyun-Wook,Son, Jong-Keun 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.9

Twenty five compounds including ten triterpenes (1-3, 5-11), six flavonoids (12-15, 24, 25), five lignans (17, 18, 21-23), two butenyl clohexnone glycosides (19-20), one fructofuranoside (16) and one fatty acid (4) were isolated from the roots of Ulmus davidiana var. japonica. The structures of those compounds were identified by comparing their physicochemical and spectral data with those of published in literatures. All the compounds were evaluated for DNA topoisomerase inhibitory activities and cytotoxicities. Among the purified compounds, 4 and 19 showed more potent inhibitory acitivities ($IC_{50}$: 39 and 19 ${\mu}M$, respectively) than camptothecin, as the positive control ($IC_{50}$: 46 ${\mu}M$) against topoisomerase I. Compounds, 4, 10, 12, 19, 24 and 25 showed strong inhibitory activities toward DNA topoisomerase II ($IC_{50}$: 0.1, 0.52, 0.47, 0.42, 0.17 ${\mu}M$ and 17 nM, respectively), which were more potent than that of etoposide as positive control ($IC_{50}$: 20 ${\mu}M$). In A549 cell line, 5 and 6 showed cytotoxicities ($IC_{50}$: 4 ${\mu}M$ and 3 ${\mu}M$, respectively, with $IC_{50}$ of camptothecin as positive control: 10.3 ${\mu}M$). In the HepG2 cell line, 3, 5 and 7 showed cytotoxicity ($IC_{50}$: 4, 3 and 4 ${\mu}M$, respectively, with $IC_{50}$ of camptothecin: 0.3 ${\mu}M$). Compounds 6, 12 and 23 showed cytotoxicities in the HT-29 cell line ($IC_{50}$: 19, 19 and 15 ${\mu}M$, respectively, with $IC_{50}$ of camptothecin: 2 ${\mu}M$).

Glioma-Associated Oncogene Homolog1 (Gli1)-Aquaporin1 pathway promotes glioma cell metastasis

( Zheng Qiang Liao ),( Ming Ye ),( Pei Gen Yu ),( Chun Xiao ),( Feng Yun Lin ) 생화학분자생물학회(구 한국생화학분자생물학회) 2016 BMB Reports Vol.49 No.7

Glioma-Associated Oncogene Homolog1 (Gli1) is known to be activated in malignant glioma; however, its downstream pathway has not been fully explained. The aim of this study was to explore the role of Gli1-Aquaporin1 (AQP1) signal pathway in glioma cell survival. Our data suggests that both Gli1 and AQP1 are upregulated in glioma tissues, as in comparison to in normal tissues. These up-regulation phenomena were also observed in glioma U251 and U87 cells. It was demonstrated that Gli1 positively regulated the AQP1 expression. By luciferase reporter gene and ChIP assay, we observed that this modulation process was realized by combination of Gli1 with AQP1 promotor. In addition, knock down of Gli1 by siRNA interference reduced the viability of glioma cells as well as suppressed cell metastasis. Also, the inhibitory effects of cell survival by silenced Gli1 were abrogated by AQP1 overexpression. In summary, glioma cell survival is a regulatory process and can be mediated by Gli1-AQP1 pathway. [BMB Reports 2016; 49(7): 394-399]