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Moving Targets Detection Based on Moving Saliency Calculation
Wang Hui-bin,Du Min,Chen Zhe,Lu Miao 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.9
Moving targets saliency extraction is the key technology in moving target detection, tracking and recognition systems. In order to solve the problems for moving targets detection tasks, such as the background interference, target occlusion and so on, a new moving target detection method by moving saliency calculation is proposed. By the Quaternion Fast Fourier Transform, the proposed method fuses four motion features as optical flows, direction vectors and frame difference. The moving saliency map, as the result, is generated. The experimental result demonstrates that our method has better ability to handle the problems in moving object detection, such as moving information loss in complex scene. The results with better accuracy score(Cgood=0.875,Cfalse=0.028) are given by our method.
Wang, Zhe,He, Mao-Lin,Zhao, Jin-Min,Qing, Hai-Hui,Wu, Yang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5
Various studies examining the relationship between Ezrin overexpression and response to chemotherapy and clinical outcome in patients with osteosarcoma have yielded inconclusive results. We accordingly conducted a meta-analysis of 7 studies (n = 318 patients) that evaluated the correlation between Ezrin and histologic response to chemotherapy and clinical prognosis (death). Data were synthesized in receiver operating characteristic curves and with fixed-effects and random-effects likelihood ratios and risk ratios. Quantitative synthesis showed that Ezrin is not a prognostic factor for the response to chemotherapy. The positive likelihood ratio was 0.538 (95% confidence interval [95% CI], 0.296- 0.979; random-effects calculation), and the negative likelihood ratio was 2.151 (95% CI, 0.905- 5.114; random-effects calculations). There was some between-study heterogeneity, but no study showed strong discriminating ability. Conversely, Ezrin positive status tended to be associated with a lower 2-year survival (risk ratio, 2.45; 95% CI, 1.26-4.76; random-effects calculation) with some between-study heterogeneity that disappeared when only studies that employed immunohistochemistry were considered (risk ratio, 2.97; 95% CI, 2.01- 4.40; fixed-effects calculation). To conclude, Ezrin is not associated with the histologic response to chemotherapy in patients with osteosarcoma, whereas Ezrin positivity was associated with a lower 2-year survival rate regarding risk of death at 2 years. Expression change of Ezrin is an independent prognostic factor in patients with osteosarcoma.
중국 당나라“상부면지(常敷面脂)”복합추출물의 생리활성 평가
왕철 ( Wang Zhe ),박성민 ( Sung-min Park ),이정노 ( Jung-no Lee ),윤미영 ( Mi-young Yun ) 한국미용학회 2016 한국미용학회지 Vol.22 No.4
This study was conducted to prove the scientific effect on skin cream made in ancient Chinese. Changfu Mianzhi (cream) were extracted from distilled water (SYW), 30% ethanol (SYE30), and 70% ethanol (SYE70), respectively. After that, it showed increment of total polyphenol content along with increasing ethanol content. Also, there was anti-oxdicant efficacy usingradical scavening activity on all concentration by DPPH method. As cytotoxicity test using humanderived fibroblast showed no cytotoxicity in all concentration. However, collagen contents were significantly increased 115.07% on SYW30 in HDFn. NO inflammatory mediator contents inhibited significantly about 27.7%, 41.8% on SYW, SYE70 in RAW 264.7 cells. Also, TNF-a testing result showed 36%, 85% inhibition on SYW, SYE70 and IL-1β testing result showed 45%, 41% on SYW, SYE70. In conclusion, Changfu mianzhi (cream) was confirmed to be effective for anti-wrinkle (SYW30), anti-inflammatory (SYW, SYE70), antioxidant (SYW, SYE70, SYE70). The excellence of the ancestors has been proven by this study. The the results, proving the scientific effect were as follows. There was a meaningful difference between activity of extract and evaluation of efficacy. This can use the research to do development of materials. Also, the possibility for effective cosmetic materials against wrinkles and anti-inflammatory activity was confirmed.
Synthesis of 6-Alkyloxyl-3,4-dihydro-2(1H)-quinoliones and Their Anticonvulsant Activities
Quan, Zhe Shan,Wang, Jun-Min,Rho, Jung-Rae,Kwak, Kyung-Chell,Kang, Hee-Cheol,Jun, Chang-Soo,Chai, Kyu-Yun Korean Chemical Society 2005 Bulletin of the Korean Chemical Society Vol.26 No.11
A series of 6-alkyloxyl-3,4-dihydro-2(1H)-quinoliones (5a-5n) were synthesized through nitration, reduction, diazotization, hydrolysis and alkylation from 3,4-dihydro-2(1H)-quinolione. Their structures were characterized by IR, $^1H$-NMR and MS. The anticonvulsant activity was evaluated by the Maximal electroshock test (MES) and the subcutaneous pentylenetetrazole (Metrazole) test (sc-Met). The neurotoxicity was measured by the Rotarod test (Tox). The result showed that 6-hexyloxy-3,4-dihydro-2 (1H)-quinolinone (5c) was potent in anti-MES and anti-scMet test with $ED_{50}$ of 24.0 mg/kg and 21.2 mg/kg, respectively, albeit its $TD_{50}$ (67.6 mg/kg) revealed the high neurotoxicity. 6-Benzyloxy-3,4-dihydro-2(1H)-quinolinone (5f) was less effective against MES induced seizure with $ED_{50}$ of 29.6 mg/kg, but no neurotoxicity was observed even under 300 mg/kg. Its Protective index (PI) was greater than 10 preferable to Phenytoin, Carbamazepin, Phenobarbital and Valproate.
Yu-shuai Wang,Min-zhe Fang,Sheng-dao Zheng,조진경,이태후 한국식품과학회 2021 Food Science and Biotechnology Vol.30 No.10
Tea is one of the most widely consumed aromaticbeverages in the world because of its taste and flavor,as well as due to many potential health beneficial properties. Metabolomics focuses on an in-depth analysis of allmetabolites in living organisms. In this study, 29 primarymetabolites and 25 secondary metabolites were identifiedusing GC/MS and UPLC-QTOF/MS, respectively. Further,PCA analysis showed conspicuous discrimination for theten varieties of green tea with metabolite profiling. Amongthem, organic acids, amino acids, flavan-3-ols, and flavonolglycosides varied greatly through checking the VIP valuesof the PLS-DA model. Moreover, the intrinsic and/orextrinsic factors characterizing each type of green tea werealso discussed. The chemical component marker derivedhere should be used as an important detection index, whileevaluating the tea quality, as well as while establishing thetea quality standard.
Synthesis of 6-Alkyloxyl-3,4-dihydro-2(1H)-quinoliones and Their Anticonvulsant Activities
Kyu-Yun Chai,Jun-Min Wang,노정래,Kyung-Chell Kwak,Hee-Cheol Kang,Chang-Soo Jun,Zhe-Shan Quan 대한화학회 2005 Bulletin of the Korean Chemical Society Vol.26 No.11
A series of 6-alkyloxyl-3,4-dihydro-2(1H)-quinoliones (5a-5n) were synthesized through nitration, reduction, diazotization, hydrolysis and alkylation from 3,4-dihydro-2(1H)-quinolione. Their structures were characterized by IR, 1H-NMR and MS. The anticonvulsant activity was evaluated by the Maximal electroshock test (MES) and the subcutaneous pentylenetetrazole (Metrazole) test (sc-Met). The neurotoxicity was measured by the Rotarod test (Tox). The result showed that 6-hexyloxy-3,4-dihydro-2 (1H)-quinolinone (5c) was potent in anti-MES and anti-scMet test with ED50 of 24.0 mg/kg and 21.2 mg/kg, respectively, albeit its TD50 (67.6 mg/kg) revealed the high neurotoxicity. 6-Benzyloxy-3,4-dihydro-2(1H)-quinolinone (5f) was less effective against MES induced seizure with ED50 of 29.6 mg/kg, but no neurotoxicity was observed even under 300 mg/kg. Its Protective index (PI) was greater than 10 preferable to Phenytoin, Carbamazepin, Phenobarbital and Valproate.
Su Tong,Zhang Zhe,Chen Yu,Wang Yun,Li Yumei,Xu Min,Wang Jian,Li Jing,Tian Xinping,Jin Zhengyu 대한영상의학회 2024 Korean Journal of Radiology Vol.25 No.4
Objective: To evaluate the image quality of novel dark-blood computed tomography angiography (CTA) imaging combined with deep learning reconstruction (DLR) compared to delayed-phase CTA images with hybrid iterative reconstruction (HIR), to visualize the cervical artery wall in patients with Takayasu arteritis (TAK). Materials and Methods: This prospective study continuously recruited 53 patients with TAK (mean age: 33.8 ± 10.2 years; 49 females) between January and July 2022 who underwent head-neck CTA scans. The arterial- and delayed-phase images were reconstructed using HIR and DLR. Subtracted images of the arterial-phase from the delayed-phase were then added to the original delayed-phase using a denoising filter to generate the final-dark-blood images. Qualitative image quality scores and quantitative parameters were obtained and compared among the three groups of images: Delayed-HIR, Dark-blood-HIR, and Dark-blood-DLR. Results: Compared to Delayed-HIR, Dark-blood-HIR images demonstrated higher qualitative scores in terms of vascular wall visualization and diagnostic confidence index (all P < 0.001). These qualitative scores further improved after applying DLR (Dark-blood-DLR compared to Dark-blood-HIR, all P < 0.001). Dark-blood DLR also showed higher scores for overall image noise than Dark-blood-HIR (P < 0.001). In the quantitative analysis, the contrast-to-noise ratio (CNR) values between the vessel wall and lumen for the bilateral common carotid arteries and brachiocephalic trunk were significantly higher on Darkblood- HIR images than on Delayed-HIR images (all P < 0.05). The CNR values were significantly higher for Dark-blood-DLR than for Dark-blood-HIR in all cervical arteries (all P < 0.001). Conclusion: Compared with Delayed-HIR CTA, the dark-blood method combined with DLR improved CTA image quality and enhanced visualization of the cervical artery wall in patients with TAK.