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      • KCI등재

        Saliency Detection based on Global Color Distribution and Active Contour Analysis

        ( Zhengping Hu ),( Zhenbin Zhang ),( Zhe Sun ),( Shuhuan Zhao ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.12

        In computer vision, salient object is important to extract the useful information of foreground. With active contour analysis acting as the core in this paper, we propose a bottom-up saliency detection algorithm combining with the Bayesian model and the global color distribution. Under the supports of active contour model, a more accurate foreground can be obtained as a foundation for the Bayesian model and the global color distribution. Furthermore, we establish a contour-based selection mechanism to optimize the global-color distribution, which is an effective revising approach for the Bayesian model as well. To obtain an excellent object contour, we firstly intensify the object region in the source gray-scale image by a seed-based method. The final saliency map can be detected after weighting the color distribution to the Bayesian saliency map, after both of the two components are available. The contribution of this paper is that, comparing the Harris-based convex hull algorithm, the active contour can extract a more accurate and non-convex foreground. Moreover, the global color distribution can solve the saliency-scattered drawback of Bayesian model, by the mutual complementation. According to the detected results, the final saliency maps generated with considering the global color distribution and active contour are much-improved.

      • KCI등재

        Multiple-Rod Constructs in Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis

        Zhao Jian,Nie Zheng,Zhang Zhengping,Liao Dongfa,Liu Da 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.5

        The purpose of this research was to compare the therapeutic efficacy of multiple-rod constructs vis-a-vis 2-rod constructs in the treatment of adult spinal deformity. A systematic review and meta-analysis were performed to determine whether the multiple-rod construct outperformed the 2-rod construct. We initially retrieved 357 papers, but only 12 were chosen for further meta-analysis. The rod breakage rates in the multiple-rod and the 2-rod groups were 10.66% and 29.87%, respectively. The multiple-rod construct inhibited rod breakage (odds ratio [OR], 0.28; 95% confidence interval [CI], 0.19–0.41; <i>p</i><0.001), pseudarthrosis (OR, 0.30; 95% CI, 0.18–0.50; <i>p</i><0.001) and rod fracture at the osteotomy site (OR, 0.34; 95% CI, 0.13–0.89; <i>p</i>=0.03). Furthermore, the multiple-rod construct reduces the risk of revision surgery (OR, 0.38; 95% CI, 0.20–0.73; <i>p</i>=0.04) as well as the revision risk of pseudarthrosis/rod fracture in the multiple- rod group (OR, 0.31; 95% CI, 0.18–0.52; <i>p</i><0.001), but increases the risk of caudal screw loosening (OR, 4.99; 95% CI, 1.87–13.30; <i>p</i>=0.001). There was no statistically significant difference in proximal junctional kyphosis (PJK) parameters (<i>p</i>=0.85), cerebrospinal fluid leakage (<i>p</i>=0.09), wound infection (p =0.71), age at surgery (<i>p</i>=0.62), gender distribution (<i>p</i>=0.93), body mass index (p =0.86), smoking status (<i>p</i>=0.05), hospital stay (<i>p</i>=0.09), osteoporosis (<i>p</i>=0.95), CoCr rod material (<i>p</i>=0.15), bone morphogenetic protein-2 (<i>p</i>=0.58), L5/S1 interbody fusion (<i>p</i>=0.07), high-grade osteotomies (<i>p</i>=0.07), the number of fusion levels (<i>p</i>=0.11), operation time (<i>p</i>=0.30), and blood loss volume (<i>p</i>=0.34). Regarding radiographic parameters, only preoperative sagittal vertical axis was found to be higher (weight means difference [WMD], 25.60; 95% CI, 15.43–35.77; <i>p</i><0.001) in the multiple-rod group. There was no difference in preoperative Oswestry Disability Index (ODI) (WMD, −3.32; 95% CI, −7.38 to 0.73; <i>p</i>=0.11), but the multiple-rod group had a lower ODI at follow-up (WMD, −7.71; 95% CI, −11.62 to −3.86; <i>p</i><0.001). Multiple-rod constructs could prevent rod breakage and pseudarthrosis while also lowering the revision rate, resulting in a better clinical outcome than the 2-rod construct. Nonetheless, due consideration should be given to PJK and screw loosening in multiple-rod constructs, possibly due to the increased stiffness caused by the multiple-rod structure.

      • SCIESCOPUSKCI등재

        Saliency Detection based on Global Color Distribution and Active Contour Analysis

        Hu, Zhengping,Zhang, Zhenbin,Sun, Zhe,Zhao, Shuhuan Korean Society for Internet Information 2016 KSII Transactions on Internet and Information Syst Vol.10 No.12

        In computer vision, salient object is important to extract the useful information of foreground. With active contour analysis acting as the core in this paper, we propose a bottom-up saliency detection algorithm combining with the Bayesian model and the global color distribution. Under the supports of active contour model, a more accurate foreground can be obtained as a foundation for the Bayesian model and the global color distribution. Furthermore, we establish a contour-based selection mechanism to optimize the global-color distribution, which is an effective revising approach for the Bayesian model as well. To obtain an excellent object contour, we firstly intensify the object region in the source gray-scale image by a seed-based method. The final saliency map can be detected after weighting the color distribution to the Bayesian saliency map, after both of the two components are available. The contribution of this paper is that, comparing the Harris-based convex hull algorithm, the active contour can extract a more accurate and non-convex foreground. Moreover, the global color distribution can solve the saliency-scattered drawback of Bayesian model, by the mutual complementation. According to the detected results, the final saliency maps generated with considering the global color distribution and active contour are much-improved.

      • KCI등재

        Moving Object Detection Using Sparse Approximation and Sparse Coding Migration

        ( Shufang Li ),( Zhengping Hu ),( Mengyao Zhao ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.5

        In order to meet the requirements of background change, illumination variation, moving shadow interference and high accuracy in object detection of moving camera, and strive for real-time and high efficiency, this paper presents an object detection algorithm based on sparse approximation recursion and sparse coding migration in subspace. First, low-rank sparse decomposition is used to reduce the dimension of the data. Combining with dictionary sparse representation, the computational model is established by the recursive formula of sparse approximation with the video sequences taken as subspace sets. And the moving object is calculated by the background difference method, which effectively reduces the computational complexity and running time. According to the idea of sparse coding migration, the above operations are carried out in the down-sampling space to further reduce the requirements of computational complexity and memory storage, and this will be adapt to multi-scale target objects and overcome the impact of large anomaly areas. Finally, experiments are carried out on VDAO datasets containing 59 sets of videos. The experimental results show that the algorithm can detect moving object effectively in the moving camera with uniform speed, not only in terms of low computational complexity but also in terms of low storage requirements, so that our proposed algorithm is suitable for detection systems with high real-time requirements.

      • Discrete Particle Swarm Optimization Algorithm in Flexible Hybrid Flow Shop Scheduling

        Liu Dongdong,Liu Kai,Zhao Zhengping Han Bo,Zhang Yan 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.10

        Traditional flexible flow shop scheduling cannot adapt to the work processes with existence of parallel machines, and blocks or limits the processes with no-wait constraints. Firstly, according to the problem in NWBFFSSP, which minimizes the maximum time used in the flow shop, an optimal solving model has been designed to realize the flexible flow shop scheduling with multi constraints; besides, for the distribution of machinery is improved, Finally, in the solving process, a real-time release priority strategy has been proposed to determine processing machine for each work piece. Furthermore, a methodology to detect work piece conflicts has been introduced while the conflicts are then eliminated by a kind of right moving strategy based on the maximum difference. The experimental results verify the effectiveness and feasibility of the proposed algorithm.

      • KCI등재

        Bioprospecting of Novel and Bioactive Metabolites from Endophytic Fungi Isolated from Rubber Tree Ficus elastica Leaves

        ( Zhuang Ding ),( Tao Tao ),( Lili Wang ),( Yanna Zhao ),( Huiming Huang ),( Demeng Zhang ),( Min Liu ),( Zhengping Wang ),( Jun Han ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.5

        Endophytic fungi are an important component of plant microbiota, and have the excellent capacity for producing a broad variety of bioactive metabolites. These bioactive metabolites not only affect the survival of the host plant, but also provide valuable lead compounds for novel drug discovery. In this study, forty-two endophytic filamentous fungi were isolated from Ficus elastica leaves, and further identified as seven individual taxa by ITS-rDNA sequencing. The antimicrobial activity of these endophytic fungi was evaluated against five pathogenic microorganisms. Two strains, Fes1711 (Penicillium funiculosum) and Fes1712 (Trichoderma harzianum), displayed broad-spectrum bioactivities. Our following study emphasizes the isolation, identification and bioactivity testing of chemical metabolites produced by T. harzianum Fes1712. Two new isocoumarin derivatives (1 and 2), together with three known compounds (3-5) were isolated, and their structures were elucidated using NMR and MS. Compounds 1 and 2 exhibited inhibitory activity against Escherichia coli. Our findings reveal that endophytic fungi from the rubber tree F. elastica leaves exhibit unique characteristics and are potential producers of novel natural bioactive products.

      • Memetic Two-echelon Vehicle Routing Optimization Based on Q Learning Theory and Differential Evolution Algorithm

        Liu Dongdong,Liu Kai,Wang Feng,Han Bo,Zhao Zhengping,Tan Fuxiao,Niu Lei 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.8

        In allusion to such problems as low accuracy and long convergence time in traditional two-echelon vehicle routing optimization algorithm, a Memetic algorithm (QDEMA) based on Q learning theory and differential evolution is proposed in this article to solve above problems. Firstly, it is necessary to research the two-echelon vehicle routing optimization problem and adopt the optimal segmentation method to obtain the relatively reasonable distribution plan for the first-echelon SDVRP problem in order to accordingly determine the distribution quantity of the transfer stations; secondly, the second-echelon MDVRP distribution scheme is solved to obtain the total distance and the total number of the distribution vehicles for the two-echelon optimization problem; thirdly, in allusion to the solution of the second-echelon MDVRP distribution scheme, Q learning theory and the differential evaluation algorithm are adopted to design new Memetic algorithm in order to globally optimize MDVRP distribution scheme; finally, the simulation experiment is carried out to verify the algorithm effectiveness.

      • KCI등재

        ATP6V0d2 Suppresses Alveoli Macrophage Alternative Polarization and Allergic Asthma via Degradation of PU.1

        Liu Na,Feng Yuchen,Liu Huicheng,Wu Wenliang,Liang Yuxia,Li Pingfei,Wei Zhengping,Wu Min,Tang Zhao-Hui,Han Junyan,Cheng Xiang,Liu Zheng,Laurence Arian,Li Huabin,Zhen Guohua,Yang Xiang-Ping 대한천식알레르기학회 2021 Allergy, Asthma & Immunology Research Vol.13 No.3

        Purpose Macrophages are important regulators of environmental allergen-induced airway inflammation and asthma. ATP6V0d2 is a subunit of vacuolar ATPase highly expressed in macrophages. However, the functions of ATP6V0d2 in the regulation of pathogenesis of allergic asthma remain unclear. The aim of this study is to determine the function and related molecular mechanisms of macrophage protein ATP6V0d2 in allergic asthma. Methods We compared the disease severity between female C57BL/6 wild-type and ATP6V0d2−/− mice in an ovalbumin (OVA)-induced asthma model. We also investigated the association of expression of ATP6V0d2, PU.1 and CCL17 with disease severity among asthmatic patients. Results The expression of ATP6V0d2 in sputum cells of asthmatic patients and in the lungs of OVA-challenged mice was enhanced compared to healthy subjects and their counterparts, respectively. However, ATP6V0d2-deficient mice exaggerated inflammatory cell infiltration as well as enhanced alternative activated macrophage (AAM) polarization and mucus production in an OVA-induced asthma model. Furthermore, we found that Atp6v0d2 promoted lysosomal degradation of Pu.1, which induced AAM polarization and Ccl17 production. Among asthma patients, ATP6V0d2 expression was inversely associated with disease severity, whereas PU.1 and CCL17 expression was positively associated with disease severity. Conclusions Our results identify macrophage Atp6v0d2, as an induced feedback inhibitor of asthma disease severity by promoting Pu.1 lysosomal degradation, which may in turn leads to reduced AAM polarization and Ccl17 production.

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