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      • Oriented User Group Verifiable Attribute-Based Encryption Scheme

        Xueyan Liu,Zhanming Li 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.1

        In this paper, we construct an oriented user group verifiable attribute-based encryption (OG-ABEv) scheme. Our scheme not only maintains on the security of previous ABE schemes, but also enhances two functions: (1) It integrates user group into the ABE scheme, thereby strengthening the confidentiality of data sharing and reducing excessive centralization of user rights; (2) It provides a verification method to supervising the central authority (CA). It also allows users to immediately check the correctness of the attribute keys and allows semi-trusted or untrusted CA be in our system. We formalize the concept of OG-ABEv and prove our scheme.

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        The changes of immune-related molecules within the ileal mucosa of piglets infected with porcine circovirus type 2

        Fengyang Shi,Qiuming Li,Zhanming Zou,Yang Wang,Xiaolin Hou,Yonghong Zhang,Qinye Song,Shuanghai Zhou,Huanrong Li 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.5

        Background: Enteritis is one of the most frequently reported symptoms in piglets infected with porcine circovirus type 2 (PCV2), but the immunopathogenesis has not been reported. Objectives: This study examined the effect of a PCV2 infection on the intestinal mucosal immune function through morphological observations and immune-related molecular detection. Methods: Morphological changes within the ileum of piglets during a PCV2 infection were observed. The expression of the related-molecules was analyzed using a gene chip. The immunocyte subsets were analyzed by flow cytometry. The secretory immunoglobulin A (SIgA) content was analyzed by enzyme-linked immunosorbent assay. Results: The PCV2 infection caused ileal villus damage, intestinal epithelial cells exfoliation, and an increase in lymphocytes in the lamina propria at 21 days post-infection. Differentially expressed genes occurred in the defense response, inflammatory response, and the complement and coagulation cascade reactions. Most of them were downregulated significantly at the induction site and upregulated at the effector site. The genes associated with SIgA production were downregulated significantly at the induction site. In contrast, the expression of the Toll-like receptor-related genes was upregulated significantly at the effector site. The frequencies of dendritic cells, B cells, and CD8+T cells were upregulated at the 2 sites. The SIgA content decreased significantly in the ileal mucosa. Conclusions: PCV2 infections can cause damage to the ileum that is associated with changes in immune-related gene expression, immune-related cell subsets, and SIgA production. These findings elucidated the molecular changes in the ileum after a PCV2 infection from the perspective of intestinal mucosal immunity, which provides insights into a further study for PCV2-induced enteritis.

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