Lactobacillus casei Zhang Prevents Jejunal Epithelial Damage to Early-Weaned Piglets Induced by Escherichia coli K88 via Regulation of Intestinal Mucosal Integrity, Tight Junction Proteins and Immune Factor Expression

( Yuying Wang ),( Xue Yan ),( Weiwei Zhang ),( Yuanyuan Liu ),( Deping Han ),( Kedao Teng ),( Yunfei Ma ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.6

Farm animals such as piglets are often affected by environmental stress, which can disturb the gut ecosystem. Antibiotics were commonly used to prevent diarrhea in weaned piglets, but this was banned by the European Union due to the development of antibiotic resistance. However, the use of probiotics instead of antibiotics may reduce the risk posed by pathogenic microorganisms and reduce the incidence of gastrointestinal diseases. Therefore, this study was conducted to investigate the effects of Lactobacillus casei Zhang on the mechanical barrier and immune function of early-weaned piglets infected using Escherichia coli K88 based on histomorphology and immunology. Fourteen-day-old weaned piglets were divided into a control group and experimental groups that were fed L. casei Zhang and infected with E. coli K88 with or without prefeeding and/or postfeeding of L. casei Zhang. The L. casei Zhang dose used was 107 CFU/g diet. Jejunum segments were obtained before histological, immunohistochemical, and western blot analyses were performed. In addition, the relative mRNA expression of toll receptors and cytokines was measured. Piglets fed L. casei Zhang showed significantly increased jejunum villus height, villus height-crypt depth ratio, muscle thickness, and expression of proliferating cell nuclear antigen and tight junction proteins ZO-1 and occludin. The use of L. casei Zhang effectively reduced intestinal inflammation after infection. We found that L. casei Zhang feeding prevented the jejunum damage induced by E. coli K88, suggesting that it may be a potential alternative to antibiotics for preventing diarrhea in early-weaned piglets.

Comparison of Acupuncturing Hegu (LI4) by Metal or Laser Needle on Facial Blood Perfusion Using Laser Speckle Technique

Yuying Tian,Tao Huang,Gerhard Litscher,Lu Wang,Guangjun Wang,Shuyong Jia,Yuqing Zhang,Weibo Zhang 사단법인약침학회 2011 Journal of Acupuncture & Meridian Studies Vol.4 No.3

Aim: To compare the difference of remote effects of acupuncture between metal needle and laser needle on facial blood perfusion (FBP). Methods: Hand acupuncture and laser-needle acupuncture were randomly used on Hegu (LI4)in 20 healthy volunteers. FBP was observed by speckle contrast imager before, during, and after the acupunctures. Results: For hand acupuncture there were gradual increases on the nose and left and right visor areas (p < 0.05 or p < 0.01) during the acupuncture and on an immediate increase (p < 0.01) that remained constant during the acupuncture on the forehead area but no significant increase on mouth area. During laser-needle acupuncture, on the other hand, there was a tendency of increase on the nose, left visor, and right visor areas but these were non significant. Conclusion: Hand acupuncture can influence FBP in remote places connected by meridians.

CT 검사 시 스캔 범위 내 상지 유무에 따른 영상의 질 평가(LUNG MAN 포함)

장위잉(Yuying Zhang),정하오양(Haoyang Zheng),정강교(Kang-gyo Jung),조유진(Yu-Jin Cho),조평곤(Pyong-Kon Cho) 대한방사선과학회(구 대한방사선기술학회) 2017 방사선기술과학 Vol.40 No.4

본 연구의 목적은 흉·복부 다중검출기전산화단층촬영(multi-detector computed tomography; MDCT)에서 상지를 머리 위로 위치 잡이 할 수 없는 경우 흉·복부에서 거리에 따른 인공유무를 평가하고자 하였다. 128-채널 MDCT로 흉·복부 CT를 위한 인체대상과 흉부 팬텀을 현재 임상에서 검사하고 있는 조건(120 kVp, 110 mAs, standard algorithm)으로 검사하였다. 인체 검사 시 한번은 팔을 머리 쪽으로 올리고 검사하고, 팔을 내린 후 동일한 조건으로 한 번 더 검사하였다. 흉부 팬텀 실험은 환자와 동일한 조건으로 검사를 하고, 상지팬텀을 흉·복부에서 일정한 거리(0, 3, 7 cm)를 두고 검사하였다. 목적하는 부위에 관심영역을 설정하여 CT 값, 노이즈, 신호 대 잡음비, 대조도 대 잡음비를 측정하여 평가하였다. 인체를 대상으로 획득한 영상에서 노이즈는 팔을 올렸 을 때와 비교하여 팔을 내렸을 때 지방, 갈비뼈, 근육 모두에서 증가하였다(0.79, 47.8, 27%). 팬텀 영상에서도 상 지를 아래로 내렸을 경우 근육, 폐 실질에서 노이즈가 증가하였다(31.2, 9.4%). 또한 상지의 위치가 흉･복부에서 멀어질수록(0, 3, 7 cm) 노이즈가 감소하였다. 근육에서 노이즈는 상지가 흉부와 붙어있을 경우(0 cm)를 기준으로 3 cm, 7cm 떨어졌을 때 5, 25.12% 감소하였고, 폐실질에서 5.6, 15.35% 감소하였다. 흉·복부 CT 촬영 시 갠트리 내 검사 이외의 부위(상지 등)가 위치할 경우 흉·복부로부터 약 3 cm 이상 거리를 유지시킨 후 검사를 진행하면 발생할 수 있는 인공음영을 최소화시킬 수 있을 것으로 사료된다. The purpose of this study was to evaluate whether or not there was artifact when the upper limb could not be lifted to the top of the head during multi-detector computed tomography(MDCT) scans of the chest and abdomen. Contrast radiography of the human and chest phantom was performed with 128channal MDCT. Under the same conditions(120 kVp, 110 mAs, standard algorithm)both hands lifted up and put down each time in the human experiment. In the chest phantom experiment, the radiography was carried out when the upper limb phantom was adjusted at a certain distance(0, 3, 7 cm) from the chest phantom. Subsequently, the values of Noise, CT number, SNR, and CNR were measured in the field of concern. The noise value of fat, rib, and muscle increased when the arm was lifted in humans(0.79, 47.8, 27%). Furthermore, when the upper limb was lowered, the noise value of muscle and lung increased in the phantom(31.2, 9.4%). In addition, the noise value of the muscles and lung decreased by 5, 25.12% and 5.6, 15.35% as the up-per limb moved about 0,3,7cm away from the chest. When the chest and abdominal radiography were performed, in the case of the presence of other parts outside the inspection area, the probability of artifact was minimal while the distance was more than 3cm away from the upper limb to the chest and abdomen.

The Inhibitory Effect of Ginseng Pectin on L-929 Cell Migration

Yuying Fan,Hairong Cheng,Dan Liu,Xu Zhang,Bo Wang,Lin Sun,Guihua Tai,Yifa Zhou 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.5

We tested the effects of ginseng pectin prepared by enzymatic hydrolysis of ginseng polysaccharides on cell migration. Ginseng pectin impaired the migration of L-929 cells and reduced their migration speed by up to 50% of control in the presence or absence of serum, suggesting it worked on both serum-dependent and serum-independent migration pathways. Ginseng pectin impaired cell migration via decreased cell spreading. These findings represent a significant contribution towards understanding the bioactivities of ginseng polysaccharides and applying them to health food and medicine.

Empirical likelihood and variable selection for partially linear single-index EV models with missing censoring indicators

Zou Yuye,Fan Guoliang,Zhang Riquan 한국통계학회 2021 Journal of the Korean Statistical Society Vol.50 No.1

In this paper, we focus on the empirical likelihood inference for partially linear single-index errors-in-variables (EV) models when the data are right censored and the censoring indicator is missing at random (MAR). Two bias-corrected empirical log-likelihood ratio (BCELR) functions for the parameters by using regressing calibration and imputation methods are introduced. The limiting distributions of the BCELRs are shown to have a mixture of central chi-squared distribution. Based on this, the confdence regions of the parameters can be constructed by using bootstrap approximation. Furthermore, as there would be some spurious covariates in the linear and nonlinear parts, a penalized empirical likelihood (PEL) approach is proposed with the help of smoothly clipped absolute deviation penalty. Two proposed PEL estimators are shown to possess the oracle property. A simulation study and a real data analysis are conducted to evaluate the fnite sample performance of the proposed methods.

船舶汚染及其防治

장길춘(Zhang Jichun),범국신(Fan Guoxin),주옥영(Zhu Yuying),서균봉(Xu Junfeng),문필은(Wen Biyin) 한국항만경제학회 1994 韓國港灣經濟學會誌 Vol.10 No.-

With research and investigation, the article illuminates the effect on the port environment resulting from the life sewage, oil sewage, gas. noise. and oil fog displaced by vessels, and further puts forward approriate strategies and measures to protect the port environment.

Fabrication of Mn-FeOx/CNTs Catalysts for Low-Temperature NO Reduction with NH3

Yanbing Zhang,Zhe Xu,Xie Wang,Xiulian Lu,Yuying Zheng 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.4

Mn-FeOx/carbon nanotubes (CNTs) catalysts were firstly prepared via simple incipient wetness method and used for low-temperature selective catalytic reduction (SCR) of NO with NH3. The structure and surface properties of the catalysts were characterized by N2 sorption, X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), high-resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS) and temperature-programmed reduction by hydrogen (H2-TPR). It was found that Mn-FeOx/CNTs catalyst exhibited excellent low-temperature SCR activity and SO2 resistance. XRD patterns revealed that metal oxides catalysts were possessed of amorphous structure. FESEM and TEM images showed that metal oxides catalysts were successfully supported on CNTs. The XPS results indicated that the obtained catalyst presented high Mn4+/Mn3+ and OS/(OS+OL) ratios. The H2-TPR profiles showed that Mn-FeOx/CNTs catalyst possessed better low-temperature reducibility. Besides, the obtained catalyst exhibited better SO2 resistance.

Removal of Nitrate in Subsoil by Denitrification in Wheat - Maize Rotation System in North China Plain

Yuming Zhang,Chunsheng Hu,Oene Oenema,Shuping Qin,Wenxu Dong,Yuying Wang 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Is There Volume Transmission Along Extracellular Fluid Pathways Corresponding to the Acupuncture Meridians?

Weibo Zhang,Ze Wang,Shuyong Jia,Yuying Tian,Guangjun Wang,Hongyan Li,Kjell Fuxe 사단법인약침학회 2017 Journal of Acupuncture & Meridian Studies Vol.10 No.1

Volume transmission is a new major communication signaling via extracellular fluid (interstitial fluid) pathways. It was proposed by the current authors that such pathways can explain the meridian phenomena and acupuncture effects. To investigate whether meridian-like structures exist in fish body and operate via volume transmission in extracellular fluid pathways, we injected alcian blue (AB) under anesthesia into Gephyrocharax melanocheir, which has a translucent body. The migration of AB could be seen directly and was recorded by a digital camera. The fish was then embedded and cut transversely to observe the position of tracks in three dimensions. Eight longitudinal threadlike blue tracks were recognized on the fish. The positions of these threadlike tracks were similar to meridians on the human body. Transverse sections showed that these tracks distributed to different layers of distinct subcutaneous loose connective tissues and intermuscular septa. Lymphatic vessels were sometimes associated with the extracellular blue tracks where the migration of AB occurred. Extracellular fluid pathways were found on fish through their transport of AB. These pathways operating via volume transmission appeared to be similar in positions and functions to the acupuncture meridians in Chinese medicine.

Nanostructures and nanomechanical properties of ion-irradiated HOPG

Zhou Yuying,Wang Ying,Lei Qiantao,Huang Qing,Zhang Wei,Yan Long 한국탄소학회 2021 Carbon Letters Vol.31 No.4

Highly Oriented Pyrolytic Graphite (HOPG) was half covered using aluminum foil and exposed to irradiation with 70 keV C+ ions at room temperature (~25 ℃). The surface layer (height=178.3±4.7 nm) of the irradiated area was destroyed, many nano-sized dendritic protrusions were observed and smooth inner layer was exposed. The peak area ratio (ID/IG) in Raman spectra increased after ion irradiation, indicating that a change in atomic structure and transformation from the sp2 to sp3 phase. The mechanical properties were explored using atomic force microscopy in peakforce mode, which revealed that the Young’s modulus of the exposed inner layer was similar to unirradiated area, while the Young’s modulus of the dendritic protrusions was higher. There fndings provid