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Bridge Health Monitoring with Consideration of Environmental Effects
Yuhee Kim,Hyunsoo Kim,Soobong Shin,Jong-Chil Park 한국비파괴검사학회 2012 한국비파괴검사학회지 Vol.32 No.6
Reliable response measurements are extremely important for proper bridge health monitoring but incomplete and unreliable data may be acquired due to sensor problems and environmental effects. In the case of a sensor malfunction, parts of the measured data can be missing so that the structural health condition cannot be monitored reliably. This means that the dynamic characteristics of natural frequencies can change as if the structure is damaged due to environmental effects, such as temperature variations. To overcome these problems, this paper proposes a systematic procedure of data analysis to recover missing data and eliminate the environmental effects from the measured data. It also proposes a health index calculated statistically using revised data to evaluate the health condition of a bridge. The proposed method was examined using numerically simulated data with a truss structure and then applied to a set of field data measured from a cable-stayed bridge.
Kim, Sumin,Kim, Jin-A.,An, Jae-Yoon,Kim, Hee-Soo,Kim, Hyun-Joong,Deng, Yuhe,Feng, Qian,Luo, Jiayan Wiley - VCHVerlag GmbH & Co. KGaA 2007 Macromolecular Materials & Engineering Vol.292 No.12
<P>The effect of wood species on the TVOC emission factor and the physico-mechanical properties of GPBs is investigated. Of the two wood species, the water absorption was higher for the GPBs made using Eucalyptus sp. than for those using Pinus massoniana. The Eucalyptus sp. GPBs pressed at room temperature, 40 and 60 °C all demonstrated higher moisture absorption than commercial GPBs. The TVOC emission factor decreased with increasing press temperature, especially for Eucalyptus sp. but remained under ‘excellent’ grade as defined by the KACA. From these results, GPB with higher content of wood particles should be considered for the replacement of wood-based panels such as particleboard and medium density fiberboard (MDF).</P><P> <img src='wiley_img_2010/14387492-2007-292-12-MAME200700192-gra001.gif' alt='wiley_img_2010/14387492-2007-292-12-MAME200700192-gra001'> </P>
Modified Supraorbital Keyhole Approach to Anterior Circulation Aneurysms
Yuhee Kim,유찬종,박철완,김명진,Dae Han Choi,Yeon Jun Kim,Kawngwoo Park 대한뇌혈관외과학회 2016 Journal of Cerebrovascular and Endovascular Neuros Vol.18 No.1
Objective:To select a surgical approach for aneurysm clipping by comparing 2 approaches. Materials and Methods:204 patients diagnosed with subarachnoid hemorrhage treated by the same neurosurgeon at a single institution from November 2011 to October 2013, 109 underwent surgical clipping. Among these, 40 patients with Hunt and Hess or Fisher grades 2 or lower were selected. Patients were assigned to Group 1 (supraorbital keyhole approach) or Group 2 (modified supraorbital approach). The prognosis according to the difference between the two surgical approaches was retrospectively compared. Results:Supraorbital keyhole approach (Group 1) was performed in 20 aneurysms (50%) and modified supraorbital approach (Group 2) was used in 20 aneurysms. Baseline characteristics of patients did not differ significantly between two groups. Total operative time (p = 0.226), early ambulation time (p = 0.755), length of hospital stay (p = 0.784), Glasgow Coma Scale at discharge (p = 0.325), and Glasgow Outcome Scale scores (p = 0.427) did not show statistically significant differences. The amount of intraoperative hemorrhage was significantly lower in the supraorbital keyhole approach (p < 0.05). Conclusion:The present series demonstrates the safety and feasibility of the two minimal invasive surgical techniques for clipping the intracranial aneurysms. The modified supraorbital keyhole approach was associated with more hemorrhage than the previous supraorbital keyhole approach, but did not exhibit differences in clinical results, and provided a better surgical view and convenience for surgeons in patients with Hunt and Hess or Fisher grades 2 or lower.
Bridge Health Monitoring with Consideration of Environmental Effects
Kim, Yuhee,Kim, Hyunsoo,Shin, Soobong,Park, Jong-Chil The Korean Society for Nondestructive Testing 2012 한국비파괴검사학회지 Vol.32 No.6
Reliable response measurements are extremely important for proper bridge health monitoring but incomplete and unreliable data may be acquired due to sensor problems and environmental effects. In the case of a sensor malfunction, parts of the measured data can be missing so that the structural health condition cannot be monitored reliably. This means that the dynamic characteristics of natural frequencies can change as if the structure is damaged due to environmental effects, such as temperature variations. To overcome these problems, this paper proposes a systematic procedure of data analysis to recover missing data and eliminate the environmental effects from the measured data. It also proposes a health index calculated statistically using revised data to evaluate the health condition of a bridge. The proposed method was examined using numerically simulated data with a truss structure and then applied to a set of field data measured from a cable-stayed bridge.
Kim, Gwi Ran,Cho, Soo-Na,Kim, Hyung-Seok,Yu, Seon Young,Choi, Sin Young,Ryu, Yuhee,Lin, Ming Quan,Jin, Li,Kee, Hae Jin,Jeong, Myung Ho Wolters Kluwer Health, Inc. All rights reserved. 2016 Journal of Hypertension Vol.34 No.11
<P>Objective:Histone deacetylase (HDAC) inhibitors have been reported to improve essential and secondary hypertension. However, the specific HDAC that might serve as a therapeutic target and the associated upstream and downstream molecules involved in regulating hypertension remain unknown. Our study was aimed at investigating whether a selective inhibitor of class II HDAC (MC1568) modulates hypertension, elucidating the underlying mechanism.Methods:Hypertension was established by administering angiotensin II (Ang II) to mice before treatment with MC1568. SBP was measured.Results:Treatment with MC1568 reduced elevated SBP; attenuated arterial remodeling in the kidney's small arteries and thoracic aorta; and inhibited cell cycle regulatory gene expression, vascular smooth muscle cell (VSMC) proliferation, DNA synthesis, and VSMC hypertrophy in vivo and in vitro. Ang II enhanced the expression of phosphorylated HDAC4 and GATA-binding factor 6 (GATA6) proteins, which were specifically localized in the cytoplasm of cells in the arteries of kidneys and in aortas. Forced expression and knockdown of HDAC4 increased and decreased, respectively, the proliferation and expression of cell cycle genes in VSMCs. GATA6, a newly described binding partner of HDAC4, markedly enhanced the size and number of VSMCs. Calcium(2+)/calmodulin-dependent kinase II (CaMKII), but not HDAC4, translocated from the nucleus to the cytoplasm in response to Ang II. CaMKII and protein kinase D1 were associated with VSMC hypertrophy and hyperplasia via direct interaction with HDAC4. MC1568 treatment weakened the association between HDAC4 and CaMKII.Conclusion:These results suggest that class II HDAC inhibition attenuates hypertension by negatively regulating VSMC hypertrophy and hyperplasia via the CaMKII/protein kinase D1/HDAC4/GATA6 pathway.</P>
사장교 케이블의 바람에 의한 연간 누적 진동횟수 추정 기법
김병철 ( Kim Byeong Cheol ),서동우 ( Seo Dong-woo ),나원기 ( Na Wongi ),김유희 ( Kim Yuhee ),박기태 ( Park Ki-tae ) 한국구조물진단유지관리공학회 2020 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.24 No.1
본 연구에서는 사장교 케이블 시스템 안전성 평가를 위한 정착구 스트랜드 모니터링을 위하여 센서 개발 및 실 교량을 대상으로 한 현장적용 시 문제점 도출을 수행하였다. 테스트베드 교량으로 케이블 이탈 사고가 발생한 MS타입 사장교를 선정하였다. 스트랜드 이탈 모니터링을 위하여 전자기를 기반으로 한 센서를 설치하여 데이터 계측 및 분석을 통한 검증 실험을 수행하였다. 센서의 검증을 위하여 데이터 수집장치(DAQ)가 있는 위치에서 특정 측정 장비를 이용해서 데이터를 취득할 수 있게 설치하여 실험을 수행하였고, 현재 그 결과를 바탕으로 상시 모니터링 시스템을 구축중에 있다.
Auxin stimulates <i>DWARF4</i> expression and brassinosteroid biosynthesis in Arabidopsis
Chung, Yuhee,Maharjan, Puna M.,Lee, Oksun,Fujioka, Shozo,Jang, Suyoun,Kim, Bokyung,Takatsuto, Suguru,Tsujimoto, Masafumi,Kim, Hobang,Cho, Seoae,Park, Taesung,Cho, Hyunwoo,Hwang, Ildoo,Choe, Sunghwa Blackwell Publishing Ltd 2011 The Plant journal Vol.66 No.4
<P><B>Summary</B></P><P>Brassinosteroids (BRs) are growth‐promoting steroidal hormones. Despite the importance of BRs in plant biology, the signal that initiates BR biosynthesis remains unknown. Among the enzymes involved in BR biosynthesis in Arabidopsis (<I>Arabidopsis thaliana</I>), DWARF4 catalyzes the rate‐determining step. Through both the histochemical analysis of <I>DWF4pro:GUS</I> plants and the direct measurement of endogenous BR content, we discovered that BR biosynthesis is stimulated by auxin. When <I>DWF4pro:GUS</I> was subjected to auxin dose–response tests and a time‐course analysis, GUS activity started to increase at an auxin concentration of 10 n<SMALL>m</SMALL>, rising noticeably after 1 h of auxin treatment. In addition, the analysis of the <I>DWF4pro:GUS</I> line in BR‐ and auxin‐mutant backgrounds revealed that the induction by auxin requires auxin‐signaling pathways but not BRs, which implies that auxin signaling directly controls BR biosynthesis. Furthermore, chromatin immunoprecipitation assays confirmed that auxin inhibits the binding of the transcriptional repressor, BZR1, to the <I>DWF4</I> promoter. A microarray analysis that was designed to examine the transcriptomes after treatment with auxin alone or auxin plus brassinazole (a BR biosynthetic inhibitor) revealed that genes previously characterized as being auxin responsive are not properly regulated when BR biosynthesis is disrupted by brassinazole. Therefore, our results support the idea that auxin regulates BR biosynthesis, and that auxin thus relies on synthesized BRs for some of its growth‐promoting effects in Arabidopsis.</P>