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RISS 인기검색어
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- 저자 : Yuechao Zhao (검색결과 4 건)
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ZNRF1 can inhibit proliferation and stemness properties of leukemia NB4 cells
Yuechao Zhao,TongJuan Li,Lei Zhao,Jue Wang,Zhen Shang,Wei Huang,Jianfeng Zhou 한국통합생물학회 2016 Animal cells and systems Vol.20 No.4
As a newly discovered E3 ubiquitin ligase, ZNRF1 protein participates in controlling Wallerian degeneration, but the role in cancer biology has been seldom reported. We analyzed the change of proliferation, apoptosis, stemness and protein levels of AKT and STAT5 after leukemia NB4 cells were treated with ZNRF1 siRNA and with expression vector. The results showed that overexpression of ZNRF1 inhibited proliferation and increased apoptosis of NB4 cells, but ZNRF1 siRNA did not influence the proliferation and apoptosis. Over-expression of ZNRF1 diminished cancer stem cell properties and down-regulated AKT and STAT5. This is the first study to show that ZNRF1 inhibited proliferation and stemness properties of leukemia NB4 cells possibly through AKT signal and STAT5 signal.
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Yutong Zhang,Yuechao Ma,Lei Fu,Wenying Zhao 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.8
This paper is concerned with the reliable robust control for semi-Markovian jump sampled-data systems. A mode-dependent Lyapunov-Krasovskii function (LKF) which fully capture the available characteristics of real sampling period is constructed. Based on the LKF approach, Newton-Leibniz condition and convex combination method, less conservative sufficient conditions are presented, which ensure that the closed-loop systems are robust asymptotically stable and extended-dissipativity. Then, actuator failures are taken into consideration, the desired sampled-data controller can be obtained by solving the linear matrix inequalities (LMIs). Finally, two numerical examples are given to illustrate the effectiveness of the proposed method.
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Yanying Hou,Lujie Liu,Xingxing Zhang,Yuechao Zhu,Yongjun Qiu,Liming Zhao 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.115 No.-
Ion exchange resins are promising materials for separating chitooligosaccharides (COSs) with differentdegrees of polymerization (DP). The adsorbent functional groups significantly determine the interactionswith COSs and affect their adsorption and separation efficiency. This study investigated the adsorptionbehaviors of COSs on macroporous cation exchange resins with different functional groups to clarifythe functional group effect on the adsorption of COSs with different DP, which can also help to providea theoretical basis for the selection of separation medium and optimization of the separation technicsof COSs. The results showed that the adsorption of COSs on sulfonic-acid type resin DX-10 andcarboxylic-acid type resin DC-10 were favorable, and the adsorption isotherms were in accord withthe Sips model. Adsorption thermodynamics showed that temperature had opposite effects on the tworesins’ equilibrium adsorption capacity of COSs. The diffusion coefficient of COSs on DX-10 resin wasgreater, and the affinity gap between COSs on DX-10 resin was larger than that of DC-10 resin, whichis beneficial for improving the separation resolution of COSs. In contrast, the interaction energy betweenCOSs with high DP and DC-10 resin was weaker compared with DX-10, which made the elution of COSswith high DP easier.
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Dynamic measurements of hydrate based gas separation in cooled silica gel
Mingjun Yang,Yongchen Song,Lanlan Jiang,Xiaojing Wang,Weiguo Liu,Yuechao Zhao,Yu Liu,Shanrong Wang 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.1
Hydrate based gas separation is a promising method for carbon dioxide capture. The purpose of thisstudy is to analyze hydrates formation and dissociation characters when gas mixture flows throughcooled silica gel. The additives mixture (THF/SDS) was used to saturate the silica gel partly, and gasmixture (CO2/H2) was injected into it to form hydrates. Magnetic resonance imaging (MRI) images wereobtained using fast spin echo multi-slice pulse sequence. Hydrates saturations were calculatedquantitatively using MRI data. The experimental results showed that the optimal initial solutionsaturation was 34.2% in this investigation. The gas component was analyzed to assess the separationefficiency. For hydrates dissociation processes at 1 atmospheric pressure, CO2 concentrations increasedobviously. Half of the six cycles showed that more than 85.00 mol% CO2 contained in the capture gas, andthe lowest CO2 concentration was 64.83 mol%. Hydrate blockages appeared frequently, which restrictedthe contact of gas and solution and caused the incomplete transformations of residual solution tohydrates. It was a key restricted factor for hydrate based CO2 capture.
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