Isolation and Characterization of Mouse Testis Specific Serine/Threonine Kinase 5 Possessing Four Alternatively Spliced Variants

( You Heng Wei ),( Guo Long Fu ),( Hai Rong Hu ),( Gang Lin ),( Jing Chun Yang ),( Jin Hu Guo ),( Qi Quan Zhu ),( Long Yu ) 생화학분자생물학회 2007 BMB Reports Vol.40 No.5

Yaw wind effect on flutter instability of four typical bridge decks

Zhu, Le-Dong,Xu, You-Lin,Guo, Zhenshan,Chang, Guang-Zhao,Tan, Xiao Techno-Press 2013 Wind and Structures, An International Journal (WAS Vol.17 No.3

When evaluating flutter instability, it is often assumed that incident wind is normal to the longitudinal axis of a bridge and the flutter critical wind speed estimated from this direction is most unfavorable. However, the results obtained in this study via oblique sectional model tests of four typical types of bridge decks show that the lowest flutter critical wind speeds often occur in the yaw wind cases. The four types of bridge decks tested include a flat single-box deck, a flat ${\Pi}$-shaped thin-wall deck, a flat twin side-girder deck, and a truss-stiffened deck with and without a narrow central gap. The yaw wind effect could reduce the critical wind speed by about 6%, 2%, 8%, 7%, respectively, for the above four types of decks within a wind inclination angle range between $-3^{\circ}$ and $3^{\circ}$, and the yaw wind angles corresponding to the minimal critical wind speeds are between $4^{\circ}$ and $15^{\circ}$. It was also found that the flutter critical wind speed varies in an undulate manner with the increase of yaw angle, and the variation pattern is largely dependent on both deck shape and wind inclination angle. Therefore, the cosine rule based on the mean wind decomposition is generally inapplicable to the estimation of flutter critical wind speed of long-span bridges under skew winds. The unfavorable effect of yaw wind on the flutter instability of long-span bridges should be taken into consideration seriously in the future practice, especially for supper-long span bridges in strong wind regions.

TRANSIENT DYNAMIC CHARACTERISTICS OF A NON-PNEUMATIC MECHANICAL ELASTIC WHEEL ROLLING OVER A DITCH

You-Qun Zhao,Yao-Ji Deng,Fen Lin,Ming-Min Zhu,Zhen Xiao 한국자동차공학회 2018 International journal of automotive technology Vol.19 No.3

The transient dynamic characteristic of a tire, which has a significant effect on vehicle handling stability and ride comfort, is difficult to study in detail because of its highly non-linear behavior. In this study, the transient dynamic characteristics of a non-pneumatic wheel, called the mechanical elastic wheel (MEW), which was rolling over a ditch were investigated by the explicit dynamic finite element (FE) method. A three-dimensional FE model of MEW considering geometric nonlinearity, material nonlinearity and large contact deformation between the wheel and the road, was established. For the validation of the accuracy and reliability of the FE model of MEW, the simulation and the experimental results of the radial stiffness and footprint of MEW were compared and analyzed. A dynamic simulation of the validated FE model of MEW rolling over a ditch was conducted using the ABAQUS/Explicit program. The equivalent stress and the contact stress generated during the process of the rolling MEW impacting the ditch were studied in detail. The effect of the rolling speed on the transient dynamic characteristics was also analyzed based on the simulation results. The simulation results could provide guidance for the optimization of the MEW structure and vehicle dynamics.

Recycled aggregate concrete filled steel SHS beam-columns subjected to cyclic loading

You-Fu Yang,Lin-Tao Zhu 국제구조공학회 2009 Steel and Composite Structures, An International J Vol.9 No.1

The present paper provides test data to evaluate the seismic performance of recycled aggregate concrete (RAC) filled steel square hollow section (SHS) beam-columns. Fifteen specimens, including 12 RAC filled steel tubular (RACFST) columns and 3 reference conventional concrete filled steel tubular (CFST) columns, were tested under reversed cyclic flexural loading while subjected to constant axially compressive load. The test parameters include: (1) axial load level (n), from 0.05 to 0.47; and (2) recycled coarse aggregate replacement ratio (r), from 0 to 50%. It was found that, generally, the seismic performance of RACFST columns was similar to that of the reference conventional CFST columns, and RACFST columns exhibited high levels of bearing capacity and ductility. Comparisons are made with predicted RACFST beam-column bearing capacities and flexural stiffness using current design codes. A theoretical model for conventional CFST beam-columns is employed in this paper for square RACFST beam-columns. The predicted load versus deformation hysteretic curves are found to exhibit satisfactory agreement with test results.

Electromagnetic energy harvesting from structural vibrations during earthquakes

Songye Zhu,Wenai Shen,Hong-Ping Zhu,You-Lin Xu 국제구조공학회 2016 Smart Structures and Systems, An International Jou Vol.18 No.3

Energy harvesting is an emerging technique that extracts energy from surrounding environments to power low-power devices. For example, it can potentially provide sustainable energy for wireless sensing networks (WSNs) or structural control systems in civil engineering applications. This paper presents a comprehensive study on harvesting energy from earthquake-induced structural vibrations, which is typically of low frequency, to power WSNs. A macroscale pendulum-type electromagnetic harvester (MPEH) is proposed, analyzed and experimentally validated. The presented predictive model describes output power dependence with mass, efficiency and the power spectral density of base acceleration, providing a simple tool to estimate harvested energy. A series of shaking table tests in which a single-storey steel frame model equipped with a MPEH has been carried out under earthquake excitations. Three types of energy harvesting circuits, namely, a resistor circuit, a standard energy harvesting circuit (SEHC) and a voltage-mode controlled buck-boost converter were used for comparative study. In ideal cases, i.e., resistor circuit cases, the maximum electric energy of 8.72 J was harvested with the efficiency of 35.3%. In practical cases, the maximum electric energy of 4.67 J was extracted via the buck-boost converter under the same conditions. The predictive model on output power and harvested energy has been validated by the test data.

Yaw wind effect on flutter instability of four typical bridge decks

Le-Dong Zhu,You-Lin Xu,Zhenshan Guo,Guang-Zhao Chang,Xiao Tan 한국풍공학회 2013 한국풍공학회지 Vol.17 No.3

When evaluating flutter instability, it is often assumed that incident wind is normal to the longitudinal axis of a bridge and the flutter critical wind speed estimated from this direction is most unfavorable. However, the results obtained in this study via oblique sectional model tests of four typical types of bridge decks show that the lowest flutter critical wind speeds often occur in the yaw wind cases. The four types of bridge decks tested include a flat single-box deck, a flat π-shaped thin-wall deck, a flat twin side-girder deck, and a truss-stiffened deck with and without a narrow central gap. The yaw wind effect could reduce the critical wind speed by about 6%, 2%, 8%, 7%, respectively, for the above four types of decks within a wind inclination angle range between -3° and 3°, and the yaw wind angles corresponding to the minimal critical wind speeds are between 4° and 15°. It was also found that the flutter critical wind speed varies in an undulate manner with the increase of yaw angle, and the variation pattern is largely dependent on both deck shape and wind inclination angle. Therefore, the cosine rule based on the mean wind decomposition is generally inapplicable to the estimation of flutter critical wind speed of long-span bridges under skew winds. The unfavorable effect of yaw wind on the flutter instability of long-span bridges should be taken into consideration seriously in the future practice, especially for supper-long span bridges in strong wind regions.

Crosswind effects on high-sided road vehicles with and without movement

Bin Wang,You-Lin Xu,Le-Dong Zhu,Yong-Le Li 한국풍공학회 2014 한국풍공학회지 Vol.18 No.2

The safety of road vehicles on the ground in crosswind has been investigated for many years. One of the most important fundamentals in the safety analysis is aerodynamic characteristics of a vehicle in crosswind. The most common way to study the aerodynamic characteristics of a vehicle in crosswind is wind tunnel tests to measure the aerodynamic coefficients and/or pressure coefficients of the vehicle. Due to the complexity of wind tunnel test equipment and procedure, the features of flow field around the vehicle are seldom explored in a wind tunnel, particularly for the vehicle moving on the ground. As a complementary to wind tunnel tests, the numerical method using computational fluid dynamics (CFD) can be employed as an effective tool to explore the aerodynamic characteristics of as well as flow features around the vehicle. This study explores crosswind effects on a high-sided lorry on the ground with and without movement through CFD simulations together with wind tunnel tests. Firstly, the aerodynamic forces on a stationary lorry model are measured in a wind tunnel, and the results are compared with the previous measurement results. The CFD with unsteady RANS method is then employed to simulate wind flow around and wind pressures on the stationary lorry. The numerical aerodynamic forces are compared with the wind tunnel test results. Furthermore, the same CFD method is extended to investigate the moving vehicle on the ground in crosswind. The results show that the CFD results match with wind tunnel test results and the current way using aerodynamic coefficients from a stationary vehicle in crosswind is acceptable. The CFD simulation can provide more insights on flow field and pressure distribution which are difficult to be obtained by wind tunnel tests.

Calculation of eigenvalue and eigenvector derivatives with the improved Kron’s substructuring method

Yong Xia,Shun Weng,You-Lin Xu,Hong-Ping Zhu 국제구조공학회 2010 Structural Engineering and Mechanics, An Int'l Jou Vol.36 No.1

For large-scale structures, the calculation of the eigensolution and the eigensensitivity is usually very time-consuming. This paper develops the Kron’s substructuring method to compute the firstorder derivatives of the eigenvalues and eigenvectors with respect to the structural parameters. The global structure is divided into several substructures. The eigensensitivity of the substructures are calculated via the conventional manner, and then assembled into the eigensensitivity of the global structure by performing some constraints on the derivative matrices of the substructures. With the proposed substructuring method, the eigenvalue and eigenvector derivatives with respect to an elemental parameter are computed within the substructure solely which contains the element, while the derivative matrices of all other substructures with respect to the parameter are zero. Consequently this can reduce the computation cost significantly. The proposed substructuring method is applied to the GARTEUR AG-11 frame and a highway bridge, which is proved to be computationally efficient and accurate for calculation of the eigensensitivity. The influence of the master modes and the division formations are also discussed.

Effects of graded levels of cupric citrate on growth performance, antioxidant status, serum lipid metabolites and immunity, and tissue residues of trace elements in weaned pigs

Chu Cai Peng,Jia You Yan,Bin Dong,Lin Zhu,Yao Yao Tian,Li Min Gong 아세아·태평양축산학회 2017 Animal Bioscience Vol.30 No.4

Objective: The goal of this study was to investigate the effects of cupric citrate (CuCit) on growth performance, antioxidant indices, serum lipid metabolites, serum immune indices, and tissue residues of copper (Cu), zinc, and iron in weaned pigs. Methods: A total of 180 weaned pigs (Duroc×Landrace×Large White) with an average body weight of 8.98±1.21 kg were randomly assigned to a corn-soybean meal control ration, or 4 similar rations with 30, 60, 120, or 240 mg/kg Cu as CuCit. All diets contained 10 mg/kg Cu as cupric sulfate from the vitamin-mineral premix. The experiment was divided into two phases: 0 to 14 d (phase 1) and 15 to 28 d (phase 2). Results: Average daily gain (ADG; linearly, p<0.01) and average daily feed intake (ADFI; linearly and quadratically, p<0.05) were affected by an increase in CuCit during phase 2. Overall period, ADG (p<0.05) and ADFI (p<0.01) were linearly increased with increasing dietary levels of CuCit. Serum malondialdehyde concentrations (p<0.05) and glutathione peroxidase activity (p<0.01) linearly decreased and increased respectively with an increase in CuCit. Serum levels of Cu-Zn superoxide dismutase were linearly affected with an increase in CuCit (p<0.01). Hepatic malondialdehyde levels decreased with an increase in CuCit (linearly and quadratically, p<0.01). Serum total cholesterol concentrations were quadratically affected (p<0.05) and decreased in pigs fed Cu as CuCit at 60 and 120 mg/kg and increased in pigs fed 240 mg/kg Cu as CuCit. Serum high-density lipoprotein concentrations were linearly affected with an increase in CuCit (p<0.01). Serum IL-1β levels were quadratically affected (p<0.05) by dietary treatment. Compared with other treatments, 240 mg/kg Cu from CuCit quadratically increased hepatic (p<0.01) and renal (p<0.05) Cu concentrations, and quadratically decreased hepatic and renal iron concentrations (p<0.05). Conclusion: Cu administered in the form of CuCit at a dosage range of 30 to 60 mg/kg, effectively enhanced the growth performance and antioxidant status of weaned pigs.

Displacement-based design approach for highway bridges with SMA isolators

Liu, Jin-Long,Zhu, Songye,Xu, You-Lin,Zhang, Yunfeng Techno-Press 2011 Smart Structures and Systems, An International Jou Vol.8 No.2

As a practical and effective seismic resisting technology, the base isolation system has seen extensive applications in buildings and bridges. However, a few problems associated with conventional lead-rubber bearings have been identified after historical strong earthquakes, e.g., excessive permanent deformations of bearings and potential unseating of bridge decks. Recently the applications of shape memory alloys (SMA) have received growing interest in the area of seismic response mitigation. As a result, a variety of SMA-based base isolators have been developed. These novel isolators often lead to minimal permanent deformations due to the self-centering feature of SMA materials. However, a rational design approach is still missing because of the fact that conventional design method cannot be directly applied to these novel devices. In light of this limitation, a displacement-based design approach for highway bridges with SMA isolators is proposed in this paper. Nonlinear response spectra, derived from typical hysteretic models for SMA, are employed in the design procedure. SMA isolators and bridge piers are designed according to the prescribed performance objectives. A prototype reinforced concrete (RC) highway bridge is designed using the proposed design approach. Nonlinear dynamic analyses for different seismic intensity levels are carried out using a computer program called "OpenSees". The efficacy of the displacement-based design approach is validated by numerical simulations. Results indicate that a properly designed RC highway bridge with novel SMA isolators may achieve minor damage and minimal residual deformations under frequent and rare earthquakes. Nonlinear static analysis is also carried out to investigate the failure mechanism and the self-centering ability of the designed highway bridge.