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      • IGCT Self-Protection Strategy for IGCT Converters

        Hong Zeng,Xiulin Chen,Yongmin Chen,Xuejun Pan,Shunbiao Zhang,Fanglin Chen,Wenbin Zeng 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

        The high-power semiconductor IGCT is widely used in two-level or three-level IGCT converters and for these converters a comprehensive system-protection strategy may be used to protect the IGCT. But there are still some problems resulted from signal transmission delays, such as incorrect timing, low response speeds, second breakdown and those problems can result in IGCT overload failure, bridge-arm shoot-through and other consequences. In this paper, the anode voltage and current parameters gained from the IGCT device are studied as protection reference in a new GCT gate drive unit. The gate drive unit can control and process the signal logic, and execute safe and reliable switching action. The signal is simultaneously feed back to the host computer in IGCT converters to perform the switching control of other devices. This new gate unit can effectively reduce device failure rates and improve the reliability of IGCT converters systems, while reducing operating costs.

      • SCIESCOPUSKCI등재

        Double-Loop Coil Design for Wireless Power Transfer to Embedded Sensors on Spindles

        Chen, Suiyu,Yang, Yongmin,Luo, Yanting The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2

        The major drawbacks of magnetic resonant coupled wireless power transfer (WPT) to the embedded sensors on spindles are transmission instability and low efficiency of the transmission. This paper proposes a novel double-loop coil design for wirelessly charging embedded sensors. Theoretical and finite-element analyses show that the proposed coil has good transmission performance. In addition, the power transmission capability of the double-loop coil can be improved by reducing the radius difference and width difference of the transmitter and receiver. It has been demonstrated by analysis and practical experiments that a magnetic resonant coupled WPT system using the double-loop coil can provide a stable and efficient power transmission to embedded sensors.

      • KCI등재

        Novel Mutations in the UNC13D Gene Carried by a Chinese Neonate with Hemophagocytic Lymphohistiocytosis

        Yuanyuan Chen,Zhujun Wang,Yuping Cheng,Yongmin Tang 연세대학교의과대학 2013 Yonsei medical journal Vol.54 No.4

        Hemophagocytic lymphohistiocytosis (HLH) in different ethnicities has been described in the literature, but few cases in patients of Chinese descent have been reported. Here, we describe the case of a Chinese neonate presenting with HLH carrying novel, compound heterozygous mutations of the UNC13D gene, including [c.2295_2298delGCAG, p.Glu765Aspfs*27] in exon 23, c.-250C>T, c.1+30G>A, c.279C>T, c.888G>C, c.18+36A>G, c.20-48T>C, c.1977C>T, c.2296C>T, c.24-46C>T, c.26-9_26-8insC, c.2599A>G, c.28+48C>T and c.3198A>G, some of which have not been reported in the literature. Cytokine profile analyses were performed in this patient, and the results were consistent with our previous findings in HLH patients. Cytokine profile monitoring may be helpful in differentiating among various clinical phases of HLH.

      • KCI등재

        Double-Loop Coil Design for Wireless Power Transfer to Embedded Sensors on Spindles

        Suiyu Chen,Yongmin Yang,Yanting Luo 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2

        The major drawbacks of magnetic resonant coupled wireless power transfer (WPT) to the embedded sensors on spindles are transmission instability and low efficiency of the transmission. This paper proposes a novel double-loop coil design for wirelessly charging embedded sensors. Theoretical and finite-element analyses show that the proposed coil has good transmission performance. In addition, the power transmission capability of the double-loop coil can be improved by reducing the radius difference and width difference of the transmitter and receiver. It has been demonstrated by analysis and practical experiments that a magnetic resonant coupled WPT system using the double-loop coil can provide a stable and efficient power transmission to embedded sensors.

      • KCI등재

        Resilient Filtering for Delayed Markov Jump Neural Networks via Event-triggered Strategy

        Weifeng Xia,Yongmin Li,Zuxin Li,Shuxin Du,Bo Li,Wenbin Chen 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.10

        This paper deals with the event triggered filtering problem for a class of delayed discrete-time Markov jump neural networks, where a resilient filter with parameter uncertainties is adopted. The aim of this paper is to design a suitable filter which ensures that the filtering error system is stochastically stable and satisfies a prescribed mixed passivity and H∞ performance. Sufficient conditions for solvability of such a problem are developed. Basedon the obtained conditions, an explicit expression of the desired resilient filter is proposed. Finally, an example is presented to show the usefulness of the proposed scheme.

      • KCI등재

        Liver kinase B1 (LKB1) reduced inflammation and oxidative stress by regulating the AMPK/NLRP3 signaling pathway in LPS-induced lung injury

        Yue Yifeng,Zong Liwu,Chen Yongmin,Nianhai Feng,Tang Junxia,Xu Hongyu,Zhao Meiling 대한독성 유전단백체 학회 2021 Molecular & cellular toxicology Vol.17 No.4

        Background Inflammation and oxidative stress-induced molecular death are one of the important causes for lung injury in critically ill patients. LKB1 is an important protein kinase in the body and has regulated inflammation and oxidative stress. However, LKB1 control inflammation and oxidative stress in lung injury were unclear. Objective We aimed to investigate the function and mechanism of Liver kinase B1 (LKB1) in lipopolysaccharide (LPS)-induced lung injury. Result LKB1 prevented lung injury, and weakened correlation oxidative stress and inflammatory reaction in LPS-induced mice model of lung injury. Up-regulation of LKB1 reduced reactive oxygen species (ROS) production and it-induced oxidative stress, and weakened inflammatory reactions in LPS-induced lung injury A549 cells. Down-regulation of LKB1 increased ROS production and it-induced oxidative stress, and enhanced inflammatory reactions in LPS-induced lung injury A549 cells. LKB1 induced phosphorylation (p)-AMPK protein expression, and suppressed the protein expression of NLRP3 in LPS-induced mice model of lung injury and in LPS-induced lung injury A549 cells. This experiment demonstrated the inhibition of AMPK or activation of NLRP3 inflammasome reversed the anti-inflammation function of LKB1 in LPS-induced lung injury. Meanwhile, ROS-induced oxidative stress also participated in the anti-inflammation effects of LKB1 in LPS-induced lung injury. Conclusion Therefore, our results indicate that LKB1 reduced inflammation and oxidative stress by regulating the AMPK/NLRP3 signaling pathway in LPS-induced lung injury.

      • Spatial Analysis of Rural Medical Facilities Using Huff Model : A Case Study of Lankao County, Henan Province

        Pengyan Zhang,,Xing Ren,Qianqian Zhang,Jianjian He,Yongmin Chen 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.1

        Rural health care reformed in the new situation in China, indicating that the construction of medical facilities not only to solve difficult medical problems, but also to take into account the efficiency and fairness of the use of medical resources allocation. Facing these problems, the paper aims to assess the spatial distribution of rural medical services by using geographic information systems (GIS) and spatial accessibility indexes. Lankao County in Henan Province and 21 hospitals of township and county are selected as study samples. First adopted ArcGIS10.0 to collate data. Second, the authors established a network dataset to analysis the maximum coverage for hospital services space accessibility. At last, established Huff model and built a scientific evaluation for the current hospitals’ distribution. There are several findings from the case study. First, the distribution of medical facility is unbalanced in rural areas in term of per capita, such as opportunity for assessing medical services and the convenience of utilizing medical services. Second, by using the Huff Model to calculate the potential population in service regions, the Huff Model to calculate the potential population in service regions, the results showed the low efficiency of the use of medical resources and the problems in these regions.

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