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        ORiginal Article : The Risk Factors and Quality of Life in Patients with Overlapping Functional Dyspepsia or Peptic Ulcer Disease with Gastroesophageal Reflux Disease

        ( Shou Wu Lee ),( Teng Yu Lee ),( Han Chung Lien ),( Hong Zen Yeh ),( Chi Sen Chang ),( Chung Wang Ko ) The Editorial Office of Gut and Liver 2014 Gut and Liver Vol.8 No.2

        Background/Aims: Gastroesophageal reflux disease (GERD), functional dyspepsia (FD), and peptic ulcer disease (PUD) impact the daily lives of affected individuals. The aim of this study was to compare the risk factors and impacts on life quality of overlapping FD or PUD in patients with GERD. Methods: Data from patients diagnosed with GERD were collected between January and November 2009. FD was defined using the Rome III diagnostic criteria. The overlap-ping GERD-FD or GERD-PUD groups were classified as con-comitant GERD and FD or peptic ulcers. The characteristics of these individuals were analyzed. Results: There were 63, 48, and 60 patients in the GERD only, overlapping GERD-FD, and overlapping GERD-PUD groups, respectively. Significantly younger age, female gender, lower body weight and body mass index, and higher rates of tea consumption were noted in the GERD-FD group. Patients in the GERD-FD group ex-hibited the lowest quality of life scores, both with respect to physical and mental health, on the Short Form 36 domains. Conclusions: Patients with concomitant GERD and FD were more likely to be younger and female. Overlapping GERD and FD had the worst impact on the quality of life of the affected individuals. (Gut Liver 2014;8:160-164)

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        Thyroid fine-needle aspiration cytology in Taiwan: a nationwide survey and literature update

        Chien-Chin Chen,Jen-Fan Hang,Chih-Yi Liu,Yeh-Han Wang,Chiung-Ru Lai 대한병리학회 2020 Journal of Pathology and Translational Medicine Vol.54 No.5

        In Taiwan, thyroid fine-needle aspiration cytology is easily accessible and reliable for evaluating thyroid nodules. The sonographic pattern plays a major role and is the deciding factor for aspiration. We conducted a nationwide survey in 2017 and it revealed that 31% of laboratories had adopted The Bethesda System for Reporting Thyroid Cytopathology. There was a relatively high unsatisfactory rate (24.04%) and low rates of indeterminate diagnoses, including atypia of undetermined significance/follicular lesions of undetermined significance: 4.87%, and follicular neoplasm/suspicious for a follicular neoplasm: 0.35%. Moreover, the risks of malignancy in benign, atypia of undetermined significance, and suspicious for a follicular neoplasm were relatively high. These may reflect strict diagnostic criteria for indeterminate categories and better patient selection for surgery. Improvements in specimen sampling and continuing education programs are crucial. Newly-developed thyroid cytology technologies, such as immunocytochemistry, molecular testing, and computerized cytomorphometry, may further facilitate cytology diagnoses.

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