http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Positive Association of Human SHC3 Gene with Schizophrenia in a Northeast Chinese Han Population
Ye Lv,Yang Sun,Guan-Yu Wang,Jian Yin,Cheng-Jie Li,Yi-Yang Luo,Zhi-Lin Luan 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.9
Objective Schizophrenia is one of the most devastating neuropsychiatric disorders. Genetic epidemiological studies have confirmed that schizophrenia is a genetic disease. Genes promoting neurodevelopment may be potential candidates for schizophrenia. As an adaptor linking a number of tyrosine kinase receptors in multiple intracellular signaling cascades, Src homology 2 domain containing transforming protein 3 (SHC3) is a member of the Shc-like adaptor protein family, and expressed predominantly in the mature neurons of the central nervous system (CNS). In the present study, we aimed to investigate the association of SHC3 and schizophrenia. Methods An independent case-control association study was performed in a sample including 710 schizophrenia patients and 1314 healthy controls from a Northeast Chinese Han population. Results The allelic and genotypic association analyses showed that four SNPs in SHC3 significantly associated with schizophrenia(rs2316280, rs4877041, rs944485 and rs7021743). The haplotype composing of these four SNPs also showed significantly individual and global association with schizophrenia. Conclusion Our present results suggest SHC3 as a susceptibility gene for schizophrenia.
Ethylene Control of Flowering and Sex Differentiation in Three Sex Types of Inbred Melon Lines
Hongxia Ye,Tonglin Wang,Lv Lv,Yuqing Hu,Bingliang Wang 한국원예학회 2020 원예과학기술지 Vol.38 No.4
Flower types and sex expression are important traits for melon (Cucumis melo L.) and hybrid seed production. Here, we studied the effects of ethrel, aminoethoxyvinylglycine (AVG) and silver nitrate (AgNO3) on floral development and sex expression in andromonoecious, monoecious, and hermaphroditic inbred melon lines in an experimental field at Zhejiang University, Hangzhou China during the autumn of 2017. The application of 100, 200, and 400 µL·L-1 of 40% ethrel delayed the initiation of male/bisexual flowers on the main stem and inhibited the formation of lateral branches bearing female/bisexual flowers. Ethrel exposure changed the flower sex type on the main stem of the three inbred melon lines. Melon sexual types could be converted from andromonoecious to hermaphroditic, from monoecious to gynoecious, and from hermaphroditic to gynomonoecious/gynoecious and be devoid of buds destined to be male flowers. The three inbred melon lines responded differently to ethrel during floral development and sex transition, with the monoecious line being the most sensitive and the hermaphroditic line being the most insensitive. The inhibitor of ethylene biosynthesis, AVG (100 mg·L-1), and the inhibitor of ethylene action, AgNO3 (300 mg·L-1), were ineffective in altering sex expression. However, the male/bisexual flowers on the main stem formed at lower nodes in AVG- or AgNO3-treated plants, resulting in earlier flower initiation for the hermaphroditic line. Thus, the application of AVG or AgNO3 promoted earlier fruit setting in hermaphroditic melon. In addition, the use of ethrel to induce male sterility in melon could replace the expensive labor necessary for the mechanical emasculation of hybrids and ensure hybrid seed purity.
Ye, Chenglin,Li, Qiao,Li, Xinyi,Park, Chae Gyu,He, Yingxia,Zhang, Yingmiao,Wu, Bicong,Xue, Ying,Yang, Kun,Lv, Yin,Ying, Xiao-Ling,Ding, Hong-Hui,Cai, Huahua,Alkraiem, Ayman Ahmad,Njiri, Olivia,Tembo, American Society for Microbiology 2019 Infection and immunity Vol.87 No.8
<P><I>Salmonella enterica</I> serovar Typhimurium, a Gram-negative bacterium, can cause infectious diseases ranging from gastroenteritis to systemic dissemination and infection. However, the molecular mechanisms underlying this bacterial dissemination have yet to be elucidated. A study indicated that using the lipopolysaccharide (LPS) core as a ligand, <I>S</I>.</P><P><I>Salmonella enterica</I> serovar Typhimurium, a Gram-negative bacterium, can cause infectious diseases ranging from gastroenteritis to systemic dissemination and infection. However, the molecular mechanisms underlying this bacterial dissemination have yet to be elucidated. A study indicated that using the lipopolysaccharide (LPS) core as a ligand, <I>S</I>. Typhimurium was able to bind human dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (hCD209a), an HIV receptor that promotes viral dissemination by hijacking antigen-presenting cells (APCs). In this study, we showed that <I>S</I>. Typhimurium interacted with CD209s, leading to the invasion of APCs and potentially the dissemination to regional lymph nodes, spleen, and liver in mice. Shielding of the exposed LPS core through the expression of O-antigen reduces dissemination and infection. Thus, we propose that similar to HIV, <I>S</I>. Typhimurium may also utilize APCs via interactions with CD209s as a way to disseminate to the lymph nodes, spleen, and liver to initiate host infection.</P>
11-Methoxyviburtinal, A New Iridoid from Valeriana jatamansi
Ye-Gao Chen,Li-Li Yu,Rong Huang,Yu-Ping Lv,Shi-Hong Gui 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.10
Five compounds of iridoids, lignan and phenylpropanoid glycosides were isolated from the roots of Valeriana jatamansi by column chromatography. Their structures were elucidated as 11-methoxyviburtinal (1), baldrinal (2), prinsepiol-4-O-β-D-glucoside (3), coniferin (4), and hexacosanic acid (5) by spectroscopic analysis. 11- Methoxyviburtinal was a new compound, and others were isolated from the plant for the first time.
An Adaptable University Human Resource Data Management
Ye Fan,Shaoyun Guan,Honglue LV 보안공학연구지원센터 2015 International Journal of Database Theory and Appli Vol.8 No.1
Data management is the foundation of the University Human Resource Management Systems (UHRMSs). The data collected by the different departments in university human resource systems is distortion, logical confusion and unstructured. In order to overcome these defects, we design an adaptable university human resource management system. In the system, the technology of adaptive computing is adopted to enhance the self-management capability of UHRMS and decrease the complexity of management. Experimental results show that the proposed adaptable UHRMS has a lower transaction response time and a higher throughput than the traditional methods.
3’’-Hydroxyamentoflavone and Its 7-O-Methyl Ether, Two New Biflavonoids fromAristolochia contorta
Ye-Gao Chen,Li-Li Yu,Rong Huang,Jia-Chuan Liu,Yu-Ping Lv,Yong Zhao 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.11
Two new biflavonoids, 3’’-hydroxyamentoflavone-7-O-methyl ether (1) and 3’’-hydroxyamentoflavone (2), were isolated from the fruits of Aristolochia contorta Bge. Their structures were elucidated by HR-ESI-MS, 1D-, and 2D-NMR spectroscopy.
3'-Hydroxyamentoflavone and Its 7-O-Methyl Ether, Two New Biflavonoids from Aristolochia contorta
Chen Ye-Gao,Yu Li-Li,Huang Rang,Liu Jia-Chuan,Lv Yu-Ping,Zhao Yang The Pharmaceutical Society of Korea 2005 Archives of Pharmacal Research Vol.28 No.11
Two new biflavonoids, 3'-hydroxyamentoflavone-7-O-methyl ether (1) and 3'-hydroxyamentoflavone (2), were isolated from the fruits of Aristolochia contorta Bge. Their structures were elucidated by HR-ESI-MS, 1D-, and 2D-NMR spectroscopy.
11-Methoxyviburtinal, A New Iridoid from Valeriana jatamansi
Chen Ye-Gao,Yu Li-Li,Huang Rong,Lv Yu-Ping,Gui Shi-Hong The Pharmaceutical Society of Korea 2005 Archives of Pharmacal Research Vol.28 No.10
Five compounds of iridoids, lignan and phenylpropanoid glycosides were isolated from the roots of Valeriana jatamansi by column chromatography. Their structures were elucidated as 11-methoxyviburtinal (1), baldrinal (2), prinsepiol-4-O-${\beta}$-D-glucoside (3), coniferin (4), and hexacosanic acid (5) by spectroscopic analysis. 11-Methoxyviburtinal was a new compound, and others were isolated from the plant for the first time.
Identification and management the financial risks of accumulator
Yonggang Ye,Siying Lv 인하대학교 정석물류통상연구원 2009 인하대학교 정석물류통상연구원 학술대회 Vol.2009 No.10
This paper focuses on using building block approach to identify and management financial risks of acumulator which is a kind of high-riskand complex financial derivative. When the underlying asset pricek rise, the investors could earn a lot from accumulator contracts, on the contrary, there are huge potential risks if the price falls. At present, the accumulator causes enormous losses to lots of investors, eve resulting in bankruptcy. These investors were not fully aware of the potential risks. This paper uses financial building blocks approach to decompose the accumulator into a number of well-known financial derivatives, helping investors to analyze the potential investment risks of accumulator contracts in different economic situations. Then base on the essential characteristics of accumulator, this paper proposes and testifies the proposal of hedging, making investors be fully aware of the risks of accumulator and managing the financial risks.