THE POISONOUS MUSHROOMS IN JAPAN

Yamaura, Yoshio,Yokoyama, Kazumasa The Korean Society of Toxicology Korea Environment 1986 Toxicological Research Vol.2 No.2

Of mushrooms found in Japan, approximately 35 species are classified as poisonous mushrooms. The mushroom poisonings caused by these mushrooms are classified as three types accodring to the symptoms and their toxic constitutents. The first type is the cholera-like symptom which is induced mainly by the toxic constitutents such as cyclopeptide and gyromitrin. The second type is the neurological mainfestations induced by muscarine (cholinergic), muscimol (delirium), psilocybin (hallucinogenic) and coprine (antabuse-like).

GMO-free movement and GMO Safety Assessment Policy in Japan

Yasuaki YAMAURA 원광대학교 법학연구소 2010 의생명과학과 법 Vol.4 No.-

GMO-free movement and GMO Safety Assessment Policy in Japan

Yasuaki YAMAURA 원광대학교 법학연구소 2010 의생명과학과 법 Vol.4 No.-

Reinforcement of lipid layers by substrate surface modification with self-assembled monolayers

Daichi YAMAURA,Yasuo KIMURA,Ayumi HIRANO-IWATA,Toshio OGINO 한국진공학회 2016 한국진공학회 학술발표회초록집 Vol.2016 No.8

A novel method for fabrication of Si/C hollow core-shell nanocomposites

Kei WAKABAYASHI,Daichi YAMAURA,Kazuki ITO,Naoya KAMEDA,Toshio OGINO 한국진공학회 2016 한국진공학회 학술발표회초록집 Vol.2016 No.8

Production and Mechanical Properties of Aluminum Alloys with Dispersed Nanoscale Quasicrystalline and Amorphous Particles

Inoue, Akihisa,Kimura, Hisamichi,Yamaura, Shin-ichi 대한금속재료학회 2003 METALS AND MATERIALS International Vol.9 No.6

By the dispersion of nanoscale quasicrystalline and amorphous particles in Al phase, new Al-based alloys with good mechanical properties were developed in a high Al concentration range of 93-95 at.% for Al- Cr-Ce-Co, Al-V-Fe, Al-Ti-M and Al-Fe-Cr-Ti alloy systems. The Vickers hardness of a melt-quenched (MQ) Al_(84.6)Cr_(15.4) alloy with almost a single icosahedral quasicrystalline phase (QC) was 710. The addition of Ce and Co in the Al-Cr binary alloys was effective for the extension of the concentration range of the QC to a lower solute concentration range. The fracture strength (σ_(f)) increased to 1340 MPa for the MQ Al_(94.5)Cr₃Ce₁Co_(1.5) alloy in which the particle size and volume fraction were approximately 40 nm and 70 %, respectively. The σ_(f) of the MQ Al_(94)V₄Fe₂ alloy was 1390 MPa and the particle size and volume fraction were about 10 nm and 50 %, respectively. Similarly, σ_(f) of the MQ Al_(93)Ti₄Fe₃ alloy was 1320 MPa and the particle size and volume fraction were about 11 nm and 30 %, respectively. Powder metallurgy (P/M) Al_(93)Fe₃Cr₂Fe₂ alloy with dispersed nanoscale QC exhibited ultimate tensile strength (σ_(UTS)) of 660 MPa, 0.2 % proof stress (σ_(0.2)) of 550 MPa, plastic elongation (ε_(P)) of 4.5 %, Young's modulus (E) of 85 GPa, Vickers hardness (Hv) of 192 and specific strength (σ_(UTS)/ρ) of 2.20x10^(5) Nm/kg at room temperature and sUTS of 350 MPa, σ_(0.2) of 330 MPa and ε_(P) of 1.5 % at 573 K. The QC structure in the P/M Al_(93)Fe₃Cr₂Ti₂ alloy remained almost unchanged even after annealing for 720 ks at 573 K and good wear resistance against S50C steel was also maintained for the extruded alloy tested at sliding velocity of 0.5 to 2 m/sec. These mechanical properties are promising for the future extension of the new Al-based alloys to practical materials.

Clinical Value of CT-Guided Needle Biopsy for Retroperitoneal Lesions

Yuki Tomozawa,Yoshitaka Inaba,Hidekazu Yamaura,Yozo Sato,Mina Kato,Takaaki Kanamoto,Makoto Sakane 대한영상의학회 2011 Korean Journal of Radiology Vol.12 No.3

Objective: The purpose of this study was to investigate retrospectively the clinical procedural performance of CT-guided needle biopsy for retroperitoneal lesions. Materials and Methods: CT-guided needle biopsy was performed in 74 consecutive patients (M:F = 44:30; mean age, 59.7 years) with retroperitoneal lesions between April 1998 and June 2009. The target lesion ranged from 1.5 to 12.5 cm in size. The biopsy access path ranged from 3.5 to 11.5 cm in depth. A biopsy specimen was obtained using an 18-gauge core needle under a CT or CT-fluoroscopy guidance and with the patient under local anesthesia. The histopathological diagnoses from the biopsies were obtained. The diagnostic confirmation of the subtype of lymphoma was evaluated. Results: Satisfactory biopsy samples were obtained in 73 (99%) of 74 patients and a pathological diagnosis was made in 70 (95%) of 74 patients. Sixty three lesions were malignant (45 lymphomas, nine primary tumors, nine lymph node metastases) and seven were benign. The subtype of lymphoma was specified in 43 (96%) of 45 patients who were diagnosed with lymphoma. Analysis of the value of CT-guided biopsy in this series indicated 63 true positives, zero false positive, six true negatives and five false negatives. This test had a sensitivity of 93%, a specificity of 100% and an accuracy of 93%. No major complications were seen and minor complications were noted in seven patients (five with local hematomas, two with transient pain at the puncture site). Conclusion: CT-guided needle biopsy for retroperitoneal lesions is highly practical and useful, and particularly for determining the subtypes in patients with lymphoma. Objective: The purpose of this study was to investigate retrospectively the clinical procedural performance of CT-guided needle biopsy for retroperitoneal lesions. Materials and Methods: CT-guided needle biopsy was performed in 74 consecutive patients (M:F = 44:30; mean age, 59.7 years) with retroperitoneal lesions between April 1998 and June 2009. The target lesion ranged from 1.5 to 12.5 cm in size. The biopsy access path ranged from 3.5 to 11.5 cm in depth. A biopsy specimen was obtained using an 18-gauge core needle under a CT or CT-fluoroscopy guidance and with the patient under local anesthesia. The histopathological diagnoses from the biopsies were obtained. The diagnostic confirmation of the subtype of lymphoma was evaluated. Results: Satisfactory biopsy samples were obtained in 73 (99%) of 74 patients and a pathological diagnosis was made in 70 (95%) of 74 patients. Sixty three lesions were malignant (45 lymphomas, nine primary tumors, nine lymph node metastases) and seven were benign. The subtype of lymphoma was specified in 43 (96%) of 45 patients who were diagnosed with lymphoma. Analysis of the value of CT-guided biopsy in this series indicated 63 true positives, zero false positive, six true negatives and five false negatives. This test had a sensitivity of 93%, a specificity of 100% and an accuracy of 93%. No major complications were seen and minor complications were noted in seven patients (five with local hematomas, two with transient pain at the puncture site). Conclusion: CT-guided needle biopsy for retroperitoneal lesions is highly practical and useful, and particularly for determining the subtypes in patients with lymphoma.

Cellular Density Evaluation for Malignant Lymphoma Using Equivalent Cross-Relaxation Rate Imaging - Initial Experience

Hideyuki Nishiofuku,Shigeru Matsushima,Yoshitaka Inaba,Hidekazu Yamaura,Yozo Sato,Yasuo Morishima,Kimihiko Kichikawa 대한영상의학회 2010 Korean Journal of Radiology Vol.11 No.3

Objective: Equivalent cross-relaxation rate (ECR) imaging is an MRI technique used to evaluate quantitatively a change in the protein-water interaction. We aimed to evaluate retrospectively the usefulness of ECR imaging for the histologic classification of malignant lymphoma (ML). Materials and Methods: Institutional Review Board approval was obtained and all patients provided informed consent. The study subjects included 15 patients with untreated ML who were histologically diagnosed with follicular lymphoma (FL; n = 8) or diffuse large B-cell lymphoma (DLBCL; n = 7). All patients underwent ECR imaging and the offset frequency was set at 7 ppm. Results: The median ECR values were 71% (range; 60.7 to 75.5) in FL and 54% (50.8 to 59.4) in DLBCL (p = 0.001). The median cellular density was 1.5 0.17 × 106 / mm2 in FL and 1.0 ± 0.70 × 106 / mm2 in DLBCL (p = 0.001). The correlation coefficient between the ECR values and cellular density in ML was 0.88 (p = 0.001). In FL and DLBCL, assuming ECR value cut-off points of 60%, both sensitivity and specificity were 100%. Conclusion: A strong correlation between ECR and cellular density in ML is demonstrated and the ECR may be a useful technique to differentiate between FL and DLBCL. Objective: Equivalent cross-relaxation rate (ECR) imaging is an MRI technique used to evaluate quantitatively a change in the protein-water interaction. We aimed to evaluate retrospectively the usefulness of ECR imaging for the histologic classification of malignant lymphoma (ML). Materials and Methods: Institutional Review Board approval was obtained and all patients provided informed consent. The study subjects included 15 patients with untreated ML who were histologically diagnosed with follicular lymphoma (FL; n = 8) or diffuse large B-cell lymphoma (DLBCL; n = 7). All patients underwent ECR imaging and the offset frequency was set at 7 ppm. Results: The median ECR values were 71% (range; 60.7 to 75.5) in FL and 54% (50.8 to 59.4) in DLBCL (p = 0.001). The median cellular density was 1.5 0.17 × 106 / mm2 in FL and 1.0 ± 0.70 × 106 / mm2 in DLBCL (p = 0.001). The correlation coefficient between the ECR values and cellular density in ML was 0.88 (p = 0.001). In FL and DLBCL, assuming ECR value cut-off points of 60%, both sensitivity and specificity were 100%. Conclusion: A strong correlation between ECR and cellular density in ML is demonstrated and the ECR may be a useful technique to differentiate between FL and DLBCL.

Percutaneous transsplenic obliteration of ectopic varices following pancreaticoduodenectomy with portal vein resection and splenic vein ligation

Shohei Chatani,Yozo Sato,Nozomi Okuno,Takaaki Hasegawa,Shinichi Murata,Hidekazu Yamaura,Kazuo Hara,Yasuhiro Shimizu,Yoshitaka Inaba 소화기인터벤션의학회 2021 International journal of gastrointestinal interven Vol.10 No.2

Left-sided portal hypertension following pancreaticoduodenectomy (PD) with portal vein resection and splenic vein ligation may cause ectopic variceal formation, potentially resulting in life-threatening bleeding. We report of a 79-year-old male suffering from severe anemia and melena after PD. Emergency endoscopy and contrast-enhanced computed tomography (CECT) revealed ectopic varices at the anastomosis site of pancreaticojejunostomy. An interventional radiology approach was preferred over surgical and endoscopic treatment because of the poor general condition and altered anatomy. In the first procedure, percutaneous transhepatic retrograde obliteration was performed using the coaxial double balloon-occlusion technique. Although hemostasis was obtained, re-bleeding occurred two months later. CECT revealed the development of another collateral pathway and the recurrence of varices. Insufficient embolization of the afferent vein was considered the cause of recurrence. Therefore, a percutaneous transsplenic approach was used, and complete embolization of varices was achieved. When transhepatic retrograde obliteration is not effective, transsplenic antegrade obliteration can be a useful therapeutic option.

Percutaneous transsplenic obliteration of ectopic varices following pancreaticoduodenectomy with portal vein resection and splenic vein ligation

Shohei Chatani,Yozo Sato,Nozomi Okuno,Takaaki Hasegawa,Shinichi Murata,Hidekazu Yamaura,Kazuo Hara,Yasuhiro Shimizu,Yoshitaka Inaba 소화기인터벤션의학회 2021 Gastrointestinal Intervention Vol.10 No.2

Left-sided portal hypertension following pancreaticoduodenectomy (PD) with portal vein resection and splenic vein ligation may cause ectopic variceal formation, potentially resulting in life-threatening bleeding. We report of a 79-year-old male suffering from severe anemia and melena after PD. Emergency endoscopy and contrast-enhanced computed tomography (CECT) revealed ectopic varices at the anastomosis site of pancreaticojejunostomy. An interventional radiology approach was preferred over surgical and endoscopic treatment because of the poor general condition and altered anatomy. In the first procedure, percutaneous transhepatic retrograde obliteration was performed using the coaxial double balloon-occlusion technique. Although hemostasis was obtained, re-bleeding occurred two months later. CECT revealed the development of another collateral pathway and the recurrence of varices. Insufficient embolization of the afferent vein was considered the cause of recurrence. Therefore, a percutaneous transsplenic approach was used, and complete embolization of varices was achieved. When transhepatic retrograde obliteration is not effective, transsplenic antegrade obliteration can be a useful therapeutic option.