Effects of Electromagnetic Radiation Exposure on Stress- Related Behaviors and Stress Hormones in Male Wistar Rats

( Seyed Mohammad Mahdavi ),( Hedayat Sahraei ),( Parichehreh Yaghmaei1 ),( Hassan Tavakoli ) 한국응용약물학회 2014 Biomolecules & Therapeutics(구 응용약물학회지) Vol.22 No.6

Studies have demonstrated that electromagnetic waves, as the one of the most important physical factors, may alter cognitive and non-cognitive behaviors, depending on the frequency and energy. Moreover, non-ionizing radiation of low energy waves e.g. very low frequency waves could alter this phenomenon via alterations in neurotransmitters and neurohormones. In this study, short, medium, and long-term exposure to the extremely low frequency electromagnetic field (ELF-EMF) (1 and 5 Hz radiation) on behavioral, hormonal, and metabolic changes in male Wistar rats (250 g) were studied. In addition, changes in plasma concentrations for two main stress hormones, noradrenaline and adrenocorticotropic hormone (ACTH) were evaluated. ELF-EMF exposure did not alter body weight, and food and water intake. Plasma glucose level was increased and decreased in the groups which exposed to the 5 and 1Hz wave, respectively. Plasma ACTH concentration increased in both using frequencies, whereas noradrenaline concentration showed overall reduction. At last, numbers of rearing, sniffing, locomotor activity was increased in group receiving 5 Hz wave over the time. In conclusions, these data showed that the effects of 1 and 5 Hz on the hormonal, metabolic and stress-like behaviors may be different. Moreover, the influence of waves on stress system is depending on time of exposure.

The accuracy of fragility curves of the steel moment-resisting frames and SDOF systems

Saman Yaghmaei-Sabegh,Ali Jafari,Mahdi Eghbali 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.39 No.3

In the present paper, a Monte Carlo-based framework is developed to investigate the accuracy and reliability of analytical fragility curves of steel moment-resisting frames and simple SDOF systems. It is also studied how the effectiveness of incremental dynamic analysis (IDA) and multiple stripes analysis (MSA) approaches, as two common nonlinear dynamic analysis methods, are influenced by the number of records and analysis stripes in fragility curves producing. Results showed that the simple SDOF systems do not provide accurate and reliable fragility curves compared with realistic steel moment-resisting structures. It is demonstrated that, the effectiveness of nonlinear dynamic analysis approaches is dependent on the fundamental period of structures, where in short-period structures, IDA is found to be more effective approach compared with MSA. This difference between the effectiveness of two analysis approaches decreases as the fundamental period of structures become longer. Using of 2 or 3 analysis stripes in MSA approach leads to significant inaccuracy and unreliability in the estimated fragility curves. Additionally, 15 number of ground motion records is recommended as a threshold of significant unreliability in estimated fragility curves, constructed by MSA.

An equivalent linear SDOF system for prediction of nonlinear displacement demands of non-ductile reinforced concrete buildings with shear walls

Saman Yaghmaei-Sabegh,Shabnam Neekmanesh,Nelson Lam,Anita Amirsardari,Nasser Taghizadieh 국제구조공학회 2023 Structural Engineering and Mechanics, An Int'l Jou Vol.85 No.5

Reinforced concrete (RC) shear wall structures are one of the most widely used structural systems to resist seismic loading all around the world. Although there have been several efforts to provide conceptually simple procedures to reasonably assess the seismic demands of structures over recent decades, it seems that lesser effort has been put on a number of structural forms such as RC shear wall structures. Therefore, this study aims to represent a simple linear response spectrum-based method which can acceptably predict the nonlinear displacements of a non-ductile RC shear wall structure subjected to an individual ground motion record. An effective period and an equivalent damping ratio are introduced as the dynamic characteristics of an equivalent linear SDOF system relevant to the main structure. By applying the fundamental mode participation factor of the original MDOF structure to the linear spectral response of the equivalent SDOF system, an acceptable estimation of the nonlinear displacement response is obtained. Subsequently, the accuracy of the proposed method is evaluated by comparison with another approximate method which is based on linear response spectrum. Results show that the proposed method has better estimations for maximum nonlinear responses and is more utilizable and applicable than the other one.

Observation of fluid layering and reverse motion in double-walled carbon nanotubes

K. Yaghmaei,H. Rafii-Tabar 한국물리학회 2009 Current Applied Physics Vol.9 No.6

Most modelling-based research in the field of carbon nanotube-related nano-fluidics has been concerned with the fluid flow in single-walled carbon nanotubes (SWCNTs), showing that the dynamics of the channel affect the structure and behaviour of the fluid. We have extended this work by modelling the flow of Ar in a double-walled carbon nanotube, and have modelled the flow in both the inner shell and the outer annular region of such a nanotube. We have found that the flows in these channels are strongly correlated, such that the fluid moves in opposite directions in these two regions. This phenomenon can give rise to a circulatory motion which can be exploited in nano-fluidic devices. Fluid layering phenomenon, that is usually associated with the flow of fluids in nano-scale channels, is also observed. Furthermore, we have also found that the fluid velocity in dynamic channels is smaller than in static channels, in line with the findings reported for single-walled carbon nanotubes. Most modelling-based research in the field of carbon nanotube-related nano-fluidics has been concerned with the fluid flow in single-walled carbon nanotubes (SWCNTs), showing that the dynamics of the channel affect the structure and behaviour of the fluid. We have extended this work by modelling the flow of Ar in a double-walled carbon nanotube, and have modelled the flow in both the inner shell and the outer annular region of such a nanotube. We have found that the flows in these channels are strongly correlated, such that the fluid moves in opposite directions in these two regions. This phenomenon can give rise to a circulatory motion which can be exploited in nano-fluidic devices. Fluid layering phenomenon, that is usually associated with the flow of fluids in nano-scale channels, is also observed. Furthermore, we have also found that the fluid velocity in dynamic channels is smaller than in static channels, in line with the findings reported for single-walled carbon nanotubes.

Indole-based derivatives effect on rats with polycystic ovary syndrome

Parichehreh Yaghmaei,Babak Dehestani,Samira Ghorbani,Farzaneh Abbasi,Azadeh Ebrahim‑Habibi 한국약제학회 2017 Journal of Pharmaceutical Investigation Vol.47 No.5

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in women of reproductive age, for which efficient therapies are needed. In this study, PCOS was induced in rats by intraperitoneal administration of testosterone propionate (0.2 mg/kg). Indole-based compounds 5-hydroxy indole-2-carboxylic acid, N-acetyl-tryptophan, Tryptamine, l-Tryptophan and Tryptophol were administered for 8 weeks in the PCOS model, after what histopathological assessment of ovaries was performed. The number of primary follicles, corpus luteum, growing follicles and graafian follicles increased and the number and diameter of ovarian cysts decreased in all treated rats in comparison with untreated group. In conclusion, l-Tryptophan and Tryptophol were most efficient as potential therapeutic molecules.

Lack of Association between Serum Adiponectin/Leptin Levels and Medullary Thyroid Cancer

Abooshahab, Raziyeh,Yaghmaei, Parichehr,Ghadaksaz, Hoda Gholab,Hedayati, Mehdi Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.8

Background: Adipokines are bioactive proteins that mediate metabolism, inflammation and angiogenesis. Changes in the secretion of key serum adipokines - adiponectin and letpin - may be associated with obesity, cancer and metabolic disorders. Thyroid cancer is one of the most important types of endocrine cancer. Therefore, investigating the association between serum levels of adiponectin and leptin and thyroid cancer might be important. The purpose of this study was to assess adiponectin and leptin levels in medullary thyroid carcinoma (MTC) cases in order to identify novel tumor markers. Materials and Methods: This research was based on a case-control study, including 45 patients with medullary thyroid cancer (21 men and 24 women) and 45 healthy controls (24 males and 21 females). Adiponectin and leptin levels were measured by ELISA in both groups. Height and weight were measured and body mass index (kg/m2) was calculated. Results: Adiponectin and leptin levels were not significantly different between medullary thyroid carcinomas and the control group. Also, there was no correlation among age and body mass index and the disease. Conclusions: These results suggest that changes in serum adiponectin and leptin levels do not play an important role in the diagnosis or could act as as biomarkers for medullary thyroid cancer.

Medullary Thyroid Carcinoma - Circulating Status of Vaspin and Retinol Binding Protein-4 in Iranian Patients

Jabbari, Sepideh,Hedayati, Mehdi,Yaghmaei, Parichehreh,Parivar, Kazem Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15

Background: Vaspin and Retinol binding protein-4 (RBP4) are new adipokines mainly produced by adipose tissue. Considering that medullary thyroid carcinoma (MTC) is a malignant neuroendocrine tumor, and to date the relationship between serum levels of vaspin and RBP4 with MTC has not been studied, in this matched case-control study we evaluated their possible significance to this tumor type. Materials and Methods: A total of 45 patients with MTC (21 males and 24 females) and 45 healthy persons as a control group (24 males and 21 females) were selected. The two groups were matched for age, sex and body mass index. Serum Vaspin and RBP4 levels were measured by enzyme-linked immunosorbent assay (ELISA) methods in both groups. Also, weight and height were measured and body mass index was calculated too. Results: In total, patients with MTC had significantly higher serum vaspin levels compared to the controls (0.52ng/ml vs. 0.45ng/ml, P=0.0241). However, no significant difference was found in serum RBP4 concentrations between the patients with MTC and the controls ($15.2{\pm}2.55{\mu}g/ml$ versus $15.1{\pm}3.34{\mu}g/ml$, p>0.05). Conclusions: The results of this study demonstrated that serum RBP4 levels in MTC patients are not significantly different from those found in healthy individuals and did not correlate with MTC. On the other hand, higher levels of serum vaspin are associated with an increased risk of MTC. Thus Vaspin may be a novel and promising biomarker for diagnosis or confirmation of MTC in conjunction other specific tumor markers.

Zeolitic imidazolate framework biocomposite as a visible light-assisted photocatalyst: Synthesis (in-situ and blending), regeneration, and decolorization of Malachite Green

Maryam Shahmansoori,Soheila Yaghmaei,Niyaz Mohammad Mahmoodi 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.128 No.-

To overcome the limitations of current water treatment technologies, it is essential to develop non-toxicmaterials with high removal capabilities. Herein, novel green biocomposite beads, CS/ZIF-8/TiO2 (CZT),based on chitosan modified with zeolitic imidazolate framework (ZIF-8) and titania (TiO2) was introduced. The interesting and noteworthy features of this new biocomposite are its green synthesis, biocompatibility,and easy separation ability. The composite beads effectively decolorize Malachite Green (MG)dye solution using visible LED light. In the present study, the efficiency of three components of CZT biocomposite,which were synthesized by two different methods (in situ and blending), was compared toinvestigate the effect of the synthesis method, as well as the synthesis with two different amounts ofTiO2 (0.2 g, and 0.4 g) to investigate the effect of TiO2. The prepared materials through the XRD, SEM,EDS, FTIR, DRS, TGA, and RAMAN analyses were characterized. The synergistic effect of ZIF-8, TiO2, andchitosan in the biocomposite increased the photo-decolorization ability of the MG dye under visible-lightirradiation. The decolorization at the optimum pH (pH = 6.5) after 180 min reached 94.5% and at the naturalpH (pH = 3.93) after 300 min reached 98.2%. The photocatalytic decolorization reaction of the biocompositefollowed zero-order kinetics.

Optimal deep machine learning framework for vibration mitigation of seismically-excited uncertain building structures

Afshin Bahrami Rad,Javad Katebi,Saman Yaghmaei-Sabegh 국제구조공학회 2023 Structural Engineering and Mechanics, An Int'l Jou Vol.88 No.6

Deep extreme learning machine (DELM) and multi-verse optimization algorithms (MVO) are hybridized for designing an optimal and adaptive control framework for uncertain buildings. In this approach, first, a robust model predictive control (RMPC) scheme is developed to handle the problem uncertainty. The optimality and adaptivity of the proposed controller are provided by the optimal determination of the tunning weights of the linear programming (LP) cost function for clustered external loads using the MVO. The final control policy is achieved by collecting the clustered data and training them by DELM. The efficiency of the introduced control scheme is demonstrated by the numerical simulation of a ten-story benchmark building subjected to earthquake excitations. The results represent the capability of the proposed framework compared to robust MPC (RMPC), conventional MPC (CMPC), and conventional DELM algorithms in structural motion control.

A generalized ANFIS controller for vibration mitigation of uncertain building structure

Javad Palizvan Zanda,Javad Katebi,Saman Yaghmaei-Sabegh 국제구조공학회 2023 Structural Engineering and Mechanics, An Int'l Jou Vol.87 No.3

A novel combinatorial type-2 adaptive neuro-fuzzy inference system (T2-ANFIS) and robust proportional integral derivative (PID) control framework for intelligent vibration mitigation of uncertain structural system is introduced. The fuzzy logic controllers (FLCs), are designed independently of the mathematical model of the system. The type-1 FLCs, have a limited ability to reduce the effect of uncertainty, due to their fuzzy sets with a crisp degree of membership. In real applications, the consequent part of the fuzzy rules is uncertain. The type-2 FLCs, are robust to the fuzzy rules and the process parameters due to the fuzzy degree of membership functions and footprint of uncertainty (FOU). The adaptivity of the proposed method is provided with the optimum tuning of the parameters using the neural network training algorithms. In our approach, the PID control force is obtained using the generalized type-2 neuro-fuzzy in such a way that the stability and robustness of the controller are guaranteed. The robust performance and stability of the presented framework are demonstrated in a numerical study for an eleven-story seismically-excited building structure combined with an active tuned mass damper (ATMD). The results indicate that the introduced type-2 neuro-fuzzy PID control scheme is effective to attenuate plant states in the presence of the structured and unstructured uncertainties, compared to the conventional, type-1 FLC, type-2 FLC, and type-1 neuro-fuzzy PID controllers.