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염용태,김광종,김순덕,이은일,박혜경,정해륜,권희규 大韓産業醫學會 1994 대한직업환경의학회지 Vol.6 No.2
The object of this study was to evaluate the possibility of new development of polyneuropathy and microaneurysm in fundus in workers who did not have polyneuropathy and microaneurysm in fundus in the electromyogram(EMG) and ophthalmoscopic examination. The total number of subjects was 144 workers who had the EMG and funduscopic examination done at least twice. There were kinds of subjects. The one of subjects was a total of 120 workers who were examined at least twice in their annual health examination for carbon disulfide poisoning. The other subjects were a total of 24 volunteer workers who worked in the rayon manufacturing factory. The results were as follows: 1. There was no cases of polyneuropathy or microaneurysm in volunteers. 2. The new cases of polyneuropathy were detected in 12 (14.3%) out of 84 subjects, and those of microaneurysm in fundus were detected in 30 (26.5%) out of 113 subjects. 3. We investigated the variables showing difference between the new cases and other cases who had no polyneuropathy or microaneurysm in fundus in repeated examinations. The both of polyneuropathy or microaneurysm cases had higher cummulative exposure index, and most of them were workers in the department of spinning where the concentration of cs₂in air was highest in the rayon manufacturing company. 4. There were no statistically significant variables by logistic regression analysis in the polyneuropathy cases. The cummulative index and the department were the statistically significant variable in the development of microaneurysm. 5. Above findings showed that workers who had high exposure history of cs₂as the workers in spinning department, had greater chance to develop the polyneuropathy or microaneurysm. But there were some limitations to conclude the association between the cs₂exposure and development of polyneuropathy or microaneurysm. Limitations are follows : short follow-up period, small number of cases, and possibility of measurement error including imperfect sensitivity or specificity of electrodiagnostic test and examiner's difference of opthalmoscopic examination. Therefore more cases and longer follow-up period are needed to study the progression of polyneuropathy or microaneurysm.
유원상,염호기,김기환,김건,문영수,이광재 대한감염학회 1989 감염 Vol.21 No.4
A case of acute transverse myelitis associated with miliary tuberculosis is presented. A 26-year-old man was admitted to Inju University Paik Hospital because of fever and voiding difficulty. Prior to this 2nd. admission, he was managed under the diagnosis of miliary tuberculosis at our hospital and discharged with improvement. On admission, physical examination revealed normal motor and sensory function, but CSF showed pleocytosis, and managed with anti tbc. durgs under the diagnosis of tbc. meningitis, On 5th hospital day, progressive deterioration of sensory and motor function with decreased DTR on both lower exterimities were observed but CSF study and myelogram were within normal limits. Sensory and motor dysfunction progressively involved to upper spinal cord and finally T5 level was affected. Thereafter, downward recovery of sensory and motor function were observed with voiding control. Upon discharge, he has little voiding difficulty and ambulatory with mild discomfort.
소아 쭈쭈가무시병환자 28명의 임상상 및 유병기간에 따른 간접면역형광항체가의 변동상
박병규,오영균,윤희상,염명걸,유한욱,김재형,강환섭,김익상,장우현,김승환 대한감염학회 1993 감염 Vol.25 No.2
During the autumn of 1990 , we had investigated the clinical featuresw and followed the change in the direct immunofluorescent antibody(IFA) titers in 28 children with scrub typhus who resided in or near Chinju, Korea. All the children except one were diagnosed by the peak IFA titers of 1:160 or higher. The results were as follows: 1) The clinical features of our children were not different, to a large degree, from those of adults ever described in Korea literatures. But the frequence rates of skin rash, eschar and conjunctival injection were higher, those of proteinuria and hematuria were lower than those in adults and the characters of rash in our children were also quite different(faces were frequently the first site of eruption and even palms and soles were involved occasionally, initial bright red color of rash was changed into brown color during the acute phase). 2) IFA titers rose rapidly during the 2nd or 3rd week of illness and then formed plateau. When we suggest IFA titers of 1:180 or higher as the diagnostic criteria, the seropositivity of our children was 5/7(75%) in the 1st week and over 95% in the 2nd through 5th week of illness, and suggest IFA titers of 1:160 or higher,then the seropositivityin the 1st, 2nd and 3rd through 5th week were 3/7(43%), 23/31(74%) and over 95%,respectively. 3) IFA titers in 6-8 months after disease onset were 1:80(13 children) or 1:20( 7 children), and in one and half year (our longest follow-up period), 1:20 (3 children) showing that IFA lasts longer than one and half year after sickness. 4) From the above data (3) and the fact that majority of cases of scrub typhus occur in the autumn season in Korea, IFA titers of 1:40-1:160 should be used as the diagnostic criteria in order to distinguish between the present and past infections.