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        Construction of Hierarchical Ni(OH)2@CoMoO4 Nanoflake Composite for High-Performance Supercapacitors

        Xueqing Li,Shuang-Yan Lin,Mingyi Zhang,Ge Jiang,Hong Gao 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.5

        Hierarchical Ni(OH)2@CoMoO4 nanoflake composite on Ni foam was successfully constructed by electrodepositing Ni(OH)2 onto CoMoO4 nanoflake and investigated as binder-free electrodes for supercapacitor. The composite shows a large areal capacitance of 5.23 F cm-2 at current density of 8 mA cm-1, and a capacitance retention of 82.5% after 1000 cycles. The high electrochemical performances can be attributed to the hierarchical nanoflakes structure and the synergetic effect between Ni(OH)2 nanosheets and CoMoO4 nanoflakes. This work demonstrates that Ni(OH)2@CoMoO4 nanoflake composite is highly desirable for application as advanced electrochemical electrode material.

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        Microstructure and mechanical properties of yttrium aluminum garnet porous ceramics prepared by different sintering process parameters

        Yue Liu,Xueqing Yang,Kangliang Peng,Qiong Wang,Jianzhen Huang,Zilin Zhang,Jiang Lu,Hao Xu,Jieguang Song,Lin Chen 한양대학교 세라믹연구소 2019 Journal of Ceramic Processing Research Vol.20 No.4

        Yttrium aluminum garnet (YAG), which possesses excellent properties, is investigated and applied. The sintering technology of YAG porous ceramics is optimized. Results show that the porosity initially increases and then decreases with an increase of increasing temperature rate, the porosity are decreased with an increase of removing carbon temperature, the porosity are decreased with an increase of sintering temperature, the porosity are decreased with an increase of holding time. Meanwhile, the compressive strength constantly exhibits an opposite tendency. The optimization of the sintering technology of YAG porous ceramics is based on porosity and compressive strength. A good sintering technology are an increasing temperature rate of 8 oC/min, a removing carbon temperature of 800 oC, removing carbon time of 1 h, a sintering temperature of 1450 oC and holding time of 2 h. The porosity of the prepared YAG porous ceramics is 57.4%, and the compressive strength is 8.89 MPa.

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        Correlation of UGT2B7 Polymorphism with Cardiotoxicity in Breast Cancer Patients Undergoing Epirubicin/Cyclophosphamide-Docetaxel Adjuvant Chemotherapy

        Hai Li,Bo Hu,Zhe Guo,Xueqing Jiang,Xinyu Su,Xiaoyi Zhang 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.1

        Purpose: The present study aimed to investigate correlations between uridine glucuronosyltransferase 2B7 (UGT2B7) -161 singlenucleotide polymorphism C to T (C>T) and the occurrence of cardiotoxicity in Chinese breast cancer (BC) patients undergoingepirubicin/cyclophosphamide-docetaxel (EC-D) adjuvant chemotherapy. Materials and Methods: 427 BC patients who had underwent surgery were consecutively enrolled in this prospective cohortstudy. All patients were scheduled to receive EC-D adjuvant chemotherapy regimen, and they were divided into UGT2B7 -161 CC(n=141), UGT2B7 -161 CT (n=196), and UGT2B7 -161 TT (n=90) groups according to their genotypes. Polymerase chain reactionwas performed for determination of UGT2B7 -161 genotypes. Cardiotoxicity was defined as an absolute decline in left ventricularejection fraction (LVEF) of at least 10% points from baseline to a value less than 53%, heart failure, acute coronary artery syndrome,or fatal arrhythmia. Results: LVEF values were lower at cycle (C) 4, C8, 3 months after chemotherapy (M3), M6, M9, and M12 compared to C0 (allp<0.001), in BC patients undergoing EC-D adjuvant chemotherapy. Cardiotoxicity was recorded for 4.2% of the overall populationand was lowest in the UGT2B7 -161 TT group (1.1%), compared to UGT2B7 -161 CT (3.1%) and UGT2B7 -161 CC (7.8%) group(p=0.026). Multivariate logistic regression revealed that UGT2B7 -161 T allele could independently predict a low occurrence ofcardiotoxicity in BC patients undergoing EC-D adjuvant chemotherapy (p=0.004). Conclusion: A UGT2B7 -161 T allele serves as a potential biomarker for predicting a low occurrence of cardiotoxicity in BC patientsundergoing EC-D adjuvant chemotherapy.

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