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      • SCIESCOPUS

        An integrated structural health monitoring system for the Xijiang high-speed railway arch bridge

        He, Xu-hui,Shi, Kang,Wu, Teng Techno-Press 2018 Smart Structures and Systems, An International Jou Vol.21 No.5

        Compared with the highway bridges, the relatively higher requirement on the safety and comfort of vehicle makes the high-speed railway (HSR) bridges need to present enhanced dynamic performance. To this end, installing a health monitor system (HMS) on selected key HSR bridges has been widely applied. Typically, the HSR takes fully enclosed operation model and its skylight time is very short, which means that it is not easy to operate the acquisition devices and download data on site. However, current HMS usually involves manual operations, which makes it inconvenient to be used for the HSR. Hence, a HMS named DASP-MTS (Data Acquisition and Signal Processing - Monitoring Test System) that integrates the internet, cloud computing (CC) and virtual instrument (VI) techniques, is developed in this study. DASP-MTS can realize data acquisition and transmission automatically. Furthermore, the acquired data can be timely shared with experts from various locations to deal with the unexpected events. The system works in a Browser/Server frame so that users at any places can obtain real-time data and assess the health situation without installing any software. The developed integrated HMS has been applied to the Xijiang high-speed railway arch bridge. Preliminary analysis results are presented to demonstrate the efficacy of the DASP-MTS as applied to the HSR bridges. This study will provide a reference to design the HMS for other similar bridges.

      • KCI등재

        Effects of wind barriers on running safety of trains for urban rail cable-stayed bridge

        Wei He,Xiang-Rong Guo,Zhi-hui Zhu,Pengru Deng,Xu-hui He 한국풍공학회 2020 Wind and Structures, An International Journal (WAS Vol.31 No.1

        Considering the wind barriers induced aerodynamic characteristic variations of both bridge deck and trains, this paper studies the effects of wind barriers on the safety and stability of trains as they run through an urban rail transit cable-stayed bridge which tends to be more vulnerable to wind due to its relatively low stiffness and lightweight. For the bridge equipped with wind barriers of different characteristics, the aerodynamic coefficients of trains and bridge decks are obtained from wind tunnel test firstly. And then, the space vibration equations of the wind-train-bridge system are established using the experimentally obtained aerodynamic coefficients. Through solving the dynamic equations, one can calculate the dynamic responses both the trains and bridge. The results indicate that setting wind barriers can effectively reduce the dynamic responses of both the trains and bridge, even though more wind forces acting on the bridge are caused by wind barriers. In addition, for urban rail transit cable-stayed bridges located in strong wind environment, the wind barriers are recommended to be set with 20% porosity and 2.5 m height according to the calculation results of cases with wind barriers porosity and height varying in two wide ranges, i.e., 10% - 40% and 2.0 m to 4.0 m, respectively.

      • KCI등재

        Effect of MoS2-Based Composite Coatings on Tribological Behavior and Efficiency of Gear

        Hui-Bo He,Hua-Ying Li,Zhe-Zhu Xu,Donguk Kim,류성기 한국정밀공학회 2010 International Journal of Precision Engineering and Vol. No.

        MoS2-based Ti composite coatings were deposited on the SCM420 alloy and gears using an RF magnetron sputtering (RFMS) system. While MoS2 coating had been coated on the silicon substrate. The coatings structures were compared to each other to find the effect of Ti. The composite coatings have been tested in a ball-on-disk tribometer to investigate tribological behavior at various conditions. The scratch test was conducted to characterize adhesion force between composite coatings and substrates. The structure of the coatings has been extensively studied by a variety of techniques, including optical microscopy, X-ray diffraction (XRD) and scanning electron microscopy (SEM), etc. The composite coatings were also applied to the gears of a reduction gearbox. The efficiency of uncoated and MoS2-based Ti coated gear was measured and compared at various input rotating speed under absorption oil film condition. It was found that the efficiency of gear had significantly improved after MoS2-based Ti composite coatings deposition.

      • Preliminary Proteomic Analysis of Thiobacillus ferrooxidans Growing on Elemental Sulphur and Fe<sup>2+</sup> Separately

        He, Zhi-guo,Hu, Yue-Hua,Zhong, Hui,Hu, Wei-Xin,Xu, Jin Korean Society for Biochemistry and Molecular Biol 2005 Journal of biochemistry and molecular biology Vol.38 No.3

        Thiobacillus ferrooxidans is one of the most important bacterium used in bioleaching, and can utilize $Fe^{2+}$ or sulphide as energy source. Growth curves for Thiobacillus ferrooxidans have been tested, which show lag, logarithmic, stationary and aging phases as seen in other bacteria. The logarithmic phases were from 10 to 32 hours for Thiobacillus ferrooxidans cultivated with $Fe^{2+}$ and from 4 to 12 days for Thiobacillus ferrooxidans cultivated with elemental sulphur. Differences of protein patterns of Thiobacillus ferrooxidans growing on elemental sulphur and $Fe^{2+}$ separately were investigated after cultivation at $30^{\circ}C$ by the analysis of two-dimensional gel electrophoresis (2-DE), matrix-assisted laser desorption/ ionization (MALDI)-Mass spectrometry and ESI-MS/MS. From the 7 identified protein spots, 11 spots were found more abundant when growing on elemental sulphur. By contrast 6 protein spots were found decreased at elemental cultivation condition. Among the proteins identified, cytochrome C have been previously identified as necessary elements of electron-transfering pathway for Thiobacillus ferrooxidans to oxidize $Fe^{2+}$; ATP synthase alpha chain and beta are expressed increased when Thiobacillus ferrooxidans cultivated with $Fe^{2+}$ as energy source. ATP synthase Beta chain is the catalytic subunit, and ATP synthase alpha chain is a regulatory subunit. The function of ATPase produces ATP from ADP in the presence of a proton gradient across the membrane.

      • Analysis of Differential-expressed Proteins of Acidithiobacillus ferrooxidans Grown under Phosphate Starvation

        He, Zhiguo,Zhong, Hui,Hu, Yuehua,Xiao, Shengmu,Liu, Jiarshe,Xu, Jin,Li, Guiyuen Korean Society for Biochemistry and Molecular Biol 2005 Journal of biochemistry and molecular biology Vol.38 No.5

        Acidithiobacillus ferrooxidans is one of the most important bacterium used in bioleaching, and can utilize $Fe^{2+}$ or sulphide as energy source. Growth curves for Acidithiobacillus ferrooxidans under phosphate starvation and normal condition have been tested, showing lag, logarithmic, stationary and aging phases as seen in other bacteria. The logarithmic phases were from 10 to 32 hours for Acidithiobacillus ferrooxidans cultivated with normal cultivating condition and from 20 to 60 hrs for Acidithiobacillus ferrooxidans cultivated phosphate starvation. Differences of protein patterns of Acidithiobacillus ferrooxidans growing in case of normal or phosphate starvation were separately investigated after cultivation at $30^{\circ}C$ by the analysis of two-dimensional gel electrophoresis (2-DE), matrix-assisted laser desorption/ionization (MALDI)-Mass spectrometry. There were total 6 protein spots identified, which were Recombination protein recA, RNA helicase, AP2 domain-containing transcription factor, NADH dehydrogenase I chain D, Hyothetical protein PF1669, and Transaldolase STY3758. From the 6 identified protein spots, 3 proteins were found to be decreased in expression at the cultivating condition of phosphate starvation, while another three upregulated.

      • SCIEKCI등재

        Effect of $MoS_2$-Based Composite Coatings on Tribological Behavior and Efficiency of Gear

        He, Hui-Bo,Li, Hua-Ying,Xu, Zhe-Zhu,Kim, Dong-Uk,Lyu, Sung-Ki 한국정밀공학회 2010 International Journal of Precision Engineering and Vol.11 No.6

        $MoS_2$-based Ti composite coatings were deposited on the SCM420 alloy and gears using an RF magnetron sputtering (RFMS) system. While $MoS_2$ coating had been coated on the silicon substrate. The coatings structures were compared to each other to find the effect of Ti. The composite coatings have been tested in a ball-on-disk tribometer to investigate tribological behavior at various conditions. The scratch test was conducted to characterize adhesion force between composite coatings and substrates. The structure of the coatings has been extensively studied by a variety of techniques, including optical microscopy, X-ray diffraction (XRD) and scanning electron microscopy (SEM), etc. The composite coatings were also applied to the gears of a reduction gearbox. The efficiency of uncoated and $MoS_2$-based Ti coated gear was measured and compared at various input rotating speed under absorption oil film condition. It was found that the efficiency of gear had significantly improved after $MoS_2$-based Ti composite coatings deposition.

      • SCISCIESCOPUS

        Antimicrobial activity of a conjugated polymer with cationic backbone

        Xu, Qingling,He, Ping,Wang, Jianwu,Chen, Hui,Lv, Fengting,Liu, Libing,Wang, Shu,Yoon, Juyoung Elsevier 2019 Dyes and pigments Vol.160 No.-

        <P><B>Abstract</B></P> <P>Owing to the misuse of antibiotics and slow development of new drugs, antibiotic-resistant pathogens have become a serious threat to human health. With the aim of developing new antimicrobial agents, we designed and synthesized a new conjugated polymer (<B>PFPhim</B>), which possesses an imidazolium containing backbone. The cationic backbone enables it to strongly interact with bacterial membrane leading to an antimicrobial ability that is more potent than that of a conjugated polymer containing a neutral backbone. <B>PFPhim</B> also displays strong photodynamic antimicrobial activity.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A conjugated polymer possessing imidazolium in the backbone was synthesized. </LI> <LI> The polymer shows good an bacterial ability over Ampr E. Coli in darkness. </LI> <LI> The polymer also displays strong photodynamic antimicrobial activity. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • Inpatients' Knowledge about Primary Liver Cancer and Hepatitis

        He, Wen-Jing,Xu, Ming-Yan,Xu, Rui-Rui,Zhou, Xiao-Qiong,Ouyang, Jun-Jie,Han, Hui,Chen, Geng-Zhen Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

        Objective: To assess the level of an inpatient population's awareness about hepatitis and primary liver cancer (PLC), the most common type of which is hepatocellular carcinoma (HCC), and then to initiate education of this group. Methods: A survey was conducted with 1300 participants within the inpatient unit in representative tertiary hospitals in the Chaoshan area of China. Structured questionnaires contained demographic data and statements about different aspects of liver cancer and hepatitis. The questionnaires were completed by trained medical practitioners after they had conducted the interviews. Results: One way ANOVA showed that the sample population lacked adequate knowledge about HCC and hepatitis. Stepwise multiple regression analysis demonstrated that the participant's level of education had the greatest impact on their total knowledge score when other variables remained constant. Conclusions: The study demonstrated: a general lack of awareness amongst the participants about the preventative strategies, and the management options available for people with primary liver cancer and hepatitis; education level was an important factor affecting knowledge levels. The demonstrated deficiencies in people's knowledge about hepatitis and HCC, and their lack of subsequent protective behaviours are likely to play an important role in HCC and hepatitis transmission or prevention.

      • Prognostic Model Built on Blood-based Biomarkers in Patients with Metastatic Colorectal Cancer

        He, Wen-Zhuo,Jiang, Chang,Yin, Chen-Xi,Guo, Gui-Fang,Rong, Ru-Ming,Qiu, Hui-Juan,Chen, Xu-Xian,Zhang, Bei,Xia, Liang-Ping Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

        Background: We had previously showed that the neutrophil lymphocyte ratio (NLR), ${\gamma}$-glutamyl transpeptidase (GGT) and carcinoembryonic antigen (CEA) are prognostic factors for metastatic colorectal cancer (mCRC) patients. In this study we developed a prognostic model based on these three indices. Materials and Methods: A total of 243 patients who were initially diagnosed as mCRC between 2005 and 2010 in the Sun Yat-sen University Cancer Center were studied. The endpoint was overall survival (OS). Results: NLR>3, elevated GGT and elevated CEA were confirmed as independent risk factors which could predict poor prognosis. Patients could be divided into three groups according to the number of risk factors they had. Those with two or three were defined as the high risk group, individuals with one risk factor as the modest risk group and patients without risk factor as the low risk group. The OS values for these three groups were 16.2 months (2.80~68.8), 24.2 months (4.07~79.0), and 37.2 months (12.6~87.8), respectively (p<0.001). Conclusions: We developed a simple but useful model based on NLR, GGT and CEA to provide prognostic information to clinical practice in highly selected mCRC patients. Further prospective and multi-center studies are warranted to test our model.

      • KCI등재

        Metabolic dynamics across prolonged diapause development in larvae of the sawfly, Cephalcia chuxiongica (Hymenoptera: Pamphiliidae)

        Xu Rong,Chen Yu-Hui,Xia Ju-Fei,Zeng Ting-Xiao,Li Yong-He,Zhu Jia-Ying 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.2

        Nutrient metabolism is crucial for the survival of insects through the diapause. However, little is known about the metabolic mechanism of prolonged diapause. The sawfly, Cephalcia chuxiongica (Hymenoptera: Pamphilii�dae), is a notorious defoliator of pine trees in southwest China. One of the distinguishing biological character�istics of this pest is the prolonged diapause of about 1.5 years. In this study, the body lipid, carbohydrate (total body sugar, glycogen, trehalose, and glucose), protein, and glycerol contents were measured in diapausing larvae of C. chuxiongica. The results showed that the changes of biochemical composition in C. chuxiongica are asso�ciated with the diapause initiation, maintenance, and termination phases. During the initiation phase, trehalose, glucose, and glycerol increased significantly, but glycogen decreased sharply. In general, the lipid, carbohydrate, and glycerol levels decreased gradually across the maintenance phase. At termination phase, the contents of glycogen and lipid persistently decreased, while an increase of trehalose, glucose, and glycerol contents were detected. The protein level was significantly higher at maintenance phase than at initiation and termination phases. It was also found that elevation of trehalose, glucose, and glycerol contents occurred in winter. These implies that the metabolites with altered levels in diapausing larvae of C. chuxiongica are responsible for maintaining a prolonged development and overwintering.

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