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Han, Bing,Zhao, Kai,Hou, Xiaoxue,Kim, Dong-Jin,Kim, Bok-Hee,Ha, Su,Norton, M. Grant,Xu, Qing,Ahn, Byung-Guk Elsevier 2017 Journal of Power Sources Vol.338 No.-
<P><B>Abstract</B></P> <P>A titanium-doped Ce<SUB>0.8</SUB>Sm<SUB>0.2</SUB>O<SUB>1.9</SUB> composite is developed as an anode component of low temperature solid oxide fuel cells running on methane fuel. Crystallographic parameters of (Ce<SUB>0.8-x</SUB>Ti<SUB>x</SUB>)Sm<SUB>0.2</SUB>O<SUB>2-δ</SUB> (0.00 < x < 0.10) are investigated with respect to the amount of titanium. The composites show a single cubic phase with the titanium amount being in the range of 0.00–0.07, while the lattice parameters decrease with increasing titanium content. The (Ce<SUB>0.8-x</SUB>Ti<SUB>x</SUB>)Sm<SUB>0.2</SUB>O<SUB>2-δ</SUB> composites are applied to an anode-supported single cell consisting of Ni-(Ce<SUB>0.8-x</SUB>Ti<SUB>x</SUB>)Sm<SUB>0.2</SUB>O<SUB>2-δ</SUB> anode/Ce<SUB>0.8</SUB>Sm<SUB>0.2</SUB>O<SUB>1.9</SUB> electrolyte/La<SUB>0.6</SUB>Sr<SUB>0.4</SUB>Co<SUB>0.2</SUB>Fe<SUB>0.8</SUB>O<SUB>3-δ</SUB> cathode. Catalytic properties of Ni-(Ce<SUB>0.8-x</SUB>Ti<SUB>x</SUB>)Sm<SUB>0.2</SUB>O<SUB>2-δ</SUB> are inspected with the electrochemical performance and performance stability of the cells in dry methane fuel. The cell with Ni-(Ce<SUB>0.73</SUB>Ti<SUB>0.07</SUB>)Sm<SUB>0.2</SUB>O<SUB>2-δ</SUB> (x = 0.07) anode displays a low polarization resistance and an optimum maximum power density (679 mW cm<SUP>−2</SUP> at 600 °C). A performance stability investigation indicates that the cell exhibits a fairly low degradation rate of 3 mV h<SUP>−1</SUP> during a 31 h operation in dry methane. These findings suggest the application potential of the titanium doped Ce<SUB>0.8</SUB>Sm<SUB>0.2</SUB>O<SUB>1.9</SUB> for the anode of solid oxide fuel cells.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Ti doped Ce<SUB>0.8</SUB>Sm<SUB>0.2</SUB>O<SUB>1.9</SUB> is found to be a potential anode material. </LI> <LI> Ni-(Ce<SUB>0.8-x</SUB>Ti<SUB>x</SUB>)Sm<SUB>0.2</SUB>O<SUB>2-δ</SUB> shows excellent electrochemical performance in methane. </LI> <LI> Good performance stability demonstrates application feasibility of the anode. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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Li Zhihua,Wang Yaru,Hou Xiaoxu,Guo Luyao,Li Yanling,Ma Yanping,Ma Yanping 한국유전학회 2023 Genes & Genomics Vol.45 No.7
Background Multiple myeloma (MM) is a common blood system malignance accompanied by monoclonal plasma cell hyperplasia. Homeobox C6 (HOXC6) acts as an oncogene in various cancers, but its function on MM is elusive. Objective The role of HOXC6 on MM development was clarified in this study. Methods HOXC6 expression and its clinical significance were determined in the peripheral blood samples collected from forty MM patients and thirty healthy adult volunteers. The overall survival was evaluated by Kaplan-Meier analysis with the log-rank test. Cell viability, proliferation and apoptosis were measured by CCK-8, EdU assay and Flow cytometry in U266 and MM.1R cells. Tumor growth was estimated by a xenograft assay. The apoptosis of tumor tissues was evaluated using TUNEL staining. The protein level in tissues was tested by immunohistochemistry. Results The HOXC6 expression was elevated in MM and high HOXC6 level was associated with the poor overall survival of MM. Besides, the HOXC6 expression was associated with hemoglobin level and ISS stage. Furthermore, silencing HOXC6 suppressed cell proliferation, induced cell apoptosis, and restrained the secretion of inflammatory factors (TNF-α, IL-6, and IL-8) in MM cells through inactivating the NF-κB pathway. Moreover, silencing HOXC6 suppressed the tumor growth of MM, the inflammatory factors levels, and the activation of NF-κB pathway but enhanced apoptosis in vivo. Conclusion HOXC6 was elevated in MM and associated with poor survival. Knockdown of HOXC6 suppressed proliferation, inflammation and tumorigenicity of MM cells via inactivating the NF-κB pathway. HOXC6 may be a meaningful target for MM therapy.
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Pengtao Yan,Lei Yan,Sumei Zhao,Zhen Zuo,Xiaoxu Wang,Chenglin Wang,Meiling Hou 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.8
A graphene-based composite with high electrochemical performance for supercapacitor applications is fabricated by introducing nanoscale carbide-derived carbon (NCDC) into the fluorine-doped graphene (FG). The incorporation of fluorine can increase the specific capacitance of graphene by providing more pseudocapacitance, whereas the introduction of NCDC into the FG/NCDC composite offers high specific surface area (SSA) (up to 1317 m2 g -1) and hierarchical pore structure, resulting in an enhanced electric double layer capacitance. Due to the synergistic effect of pseudocapacitance and electric double layer capacitance, the specific capacitance of FG/NCDC composite can reach 321 F g -1 at a scan rate of 5 mV s -1 in aqueous electrolyte. Notably, the specific capacitance of the FG/NCDC composite is very stable during long-term cyclic tests, with no significant degradation after 10,000 cycles. Due to its excellent supercapacitive performance, the FG/NCDC composite can be considered as a promising electrode material for high-performance supercapacitors.
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Xiangyu Zhang,Cunyuan Li,Xiaoyue Li,Zhijin Liu,Wei Ni,Yang Cao,Yang Yao,Esenbay Islamov,Junchang Wei,Xiaoxu Hou,Shengwei Hu 한국유전학회 2019 Genes & Genomics Vol.41 No.10
Introduction The vertebral number is an economically significant trait, which is associated with body length and carcass traits. Nuclear Receptor Subfamily 6, Group A, Member 1 (NR6A1) is a member of the nuclear receptor superfamily and it plays an important role in the early development of embryos. Objectives The NR6A1 gene was considered as an important candidate for influence vertebrae number, while the potential associations between this gene and the number of lumbar vertebrae traits of sheep have not been explored. Methods In this study, we detected the genetic variants of NR6A1 gene and analyzed the associations of the polymorphisms with lumbar number traits in 130 Kazakh sheep. We use single-strand conformation polymorphism (SSCP) technique to detect single nucleotide polymorphism (SNP) of NR6A1 gene, and the association of the genotype and lumbar number variation was analyzed by independent Chi-square test. Results We detect SNP of NR6A1 gene by PCR-SSCP technique, and polymorphisms were only found in the coding region of exon-6 and exon-8 of NR6A1 gene. In order to investigate the connection between the SNP locus and lumbar number traits in sheep, we conducted a Chi-square test for independence for exon-6 and exon-8 of NR6A1 gene, respectively. Association analysis revealed significant associations between the SNP (rs414302710: A >C) in the exon-8 of NR6A1 gene with the number of lumbar vertebrae (P < 0.01). Conclusion Our study indicated that this SNP (rs414302710: A>C) locus of exon-8 of NR6A1 gene in sheep possible influence the number of lumbar vertebrae, which has the potential to be applied in selective breeding of sheep.
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