EFFECT OF REACTION TIME ON MICROSTRUCTURE, DIELECTRIC PROPERTY AND MICROWAVE ABSORPTION PROPERTY OF Cu-DOPED SiC NANOPOWDER

XIAOLEI SU,YONGSHENG TAN,YAN JIA,KAILI ZHAO,SONGTAO LIU,XINHAI HE,CHONG FU 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.2

Cu-doped SiC nanopowders have been prepared via combustion synthesis of the silicon andcarbon system in a 0.1 MPa nitrogen atmosphere under di®erent reaction time, using copper asthe dopant and PTFE as the chemical activator, respectively. X-ray di®raction, scanning elec-tronic microscope and Raman spectra have been used to characterize the phase and morphologyof prepared nanopowders. Results indicate that the lattice constant of prepared Cu-doped SiCnanopowder decreases with extending reaction time. The prepared nanopowders have ¯nespherical particles and narrow particle size distribution and the particle size increases withincreasing reaction time. The electric permittivities of prepared Cu-doped SiC nanopowders inthe frequency range of 8.2 – 12.4 GHz have been determined. The real part " 0, imaginary part " 00and dielectric loss tg ? of complex permittivity decrease with increasing reaction time. All pre-pared Cu-doped SiC nanopowder exhibits good microwave absorption property in the frequencyrange of 8.2 – 12.4 GHz.

Improving the Machining Quality of Micro Structures by Using Electrophoresis-Assisted Ultrasonic Micromilling Machining

Junfeng He,Zhongning Guo,Haishan Lian,Junjie Wang,Xiaolei Chen,Jiangwen Liu 한국정밀공학회 2020 International Journal of Precision Engineering and Vol.7 No.1

Traditional micromilling leaves burrs and has a high surface roughness in the workpiece, which compromises the microstructural machining quality. Electrophoresis-assisted ultrasonic micromilling machining (EUMM) is proposed to solve this problem. An electrophoresis assisted electric field is applied to attract abrasive particles into the machining gap. Combined with the ultrasonic vibrations of the workpiece, the impact and grinding effect of these abrasive particles in the machining gap removes burrs that are generated during machining and reduces the surface roughness of the microstructure. Micro channels were generated for this study to verify the proposed method. The experimental results show that the EUMM significantly reduces burr formation during microchannel milling. The EUMM also decreases the surface roughness (Ra); the bottom roughness using the EUMM (0.33 µm) is lower than that with either the ultrasonic micromilling (UMM) or traditional micromilling. The EUMM also improves the sidewall roughness since the grinding and particle impacts significantly smooth the sidewalls. The particles during EUMM ensure a low surface roughness of 0.34 µm for the vertical sidewalls. Furthermore, the EUMM has a lesser effect on the width of the micro channels; as the spindle speed increases, the microchannel width only increases from 486 to 498 µm.

Profit Distribution Method for Innovative Customer Based on Linguistic Consistency

Wang Xiaolei,He Meiliang,Jiang Hongchun 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.10

Rewarding the innovative customers in collaborative innovation can increase the initiative of customer involvement and improve the performance of product innovation. Therefore, a method of customer profit distribution based on contribution degree was proposed. Firstly, customer contribution evaluation index system was established from knowledge perspective. Secondly, customer contribution evaluation method based on group linguistic consistency was put forward to determine the contribution degree, and customer profit was distributed according to the contribution degree. Two-tuple linguistic consistency was used to integrate the multi-attribute evaluation information. Finally, the feasibility and effectiveness of the proposed method was verified.

Choice of Capecitabine or S1 in Combination with Oxaliplatin based on Thymidine Phosphorylase and Dihydropyrimidine Dehydrogenase Expression Status in Patients with Advanced Gastric Cancer

Xu, Rong,He, Xiaolei,Wufuli, Reyina,Su, Ying,Ma, Lili,Chen, Ru,Han, Zhongcheng,Wang, Fang,Liu, Jiang The Korean Gastric Cancer Association 2019 Journal of gastric cancer Vol.19 No.4

Purpose: To study the efficacy of capecitabine or S-1 plus oxaliplatin (CAPOX or SOX) for treating thymidine phosphorylase (TP)- or dihydropyrimidine dehydrogenase (DPD)-positive advanced gastric cancer. Materials and Methods: Eighty-six patients with stage IIIC to IV gastric cancer were assessed for TP and DPD expression by immunohistochemistry. The association between CAPOX or SOX efficacy and TP/DPD expression was retrospectively analyzed. Results: There were no significant differences in the objective remission rate (ORR, 52.27% vs. 47.62%; P>0.05), disease control rate (72.73% vs. 73.81%, P>0.05), progression-free survival (hazard ratio [HR], 1.119; 95% confidence interval [CI], 0.739-1.741; P=0.586), and overall survival (OS; HR, 0.855; 95% CI, 0.481-1.511; P=0.588) between CAPOX and SOX. A higher number of stage IV patients showed TP positivity, while DPD-positive patients predominantly showed intestinal type of gastric cancer. In TP-positive patients, the ORRs associated with CAPOX and SOX treatments were 57.14% and 38.10%, respectively; OS was better with CAPOX than with SOX (HR, 0.447; 95% CI, 0.179-0.978; P=0.046). Among DPD-positive patients, the SOX treatment-associated ORR (60.87%) was significantly higher than the CAPOX treatment-associated ORR (43.48%). Furthermore, SOX treatment resulted in better OS than did CAPOX treatment (HR, 2.020; 95% CI, 1.019-4.837; P=0.049). Conclusions: No significant difference in clinical efficacy was found between CAPOX and SOX. TP-positive patients might respond better to CAPOX while DPD-positive patients may respond better to SOX. Our findings might serve as a guide for personalized chemotherapy for gastric cancer.

Choice of Capecitabine or S1 in Combination with Oxaliplatin based on Thymidine Phosphorylase and Dihydropyrimidine Dehydrogenase Expression Status in Patients with Advanced Gastric Cancer

Jiang Liu,Rong Xu,Xiaolei He,Reyina Wufuli,Ying Su,Lili Ma,Ru Chen,Zhongcheng Han,Fang Wang 대한위암학회 2019 Journal of gastric cancer Vol.19 No.4

Purpose: To study the efficacy of capecitabine or S-1 plus oxaliplatin (CAPOX or SOX) for treating thymidine phosphorylase (TP)- or dihydropyrimidine dehydrogenase (DPD)-positive advanced gastric cancer. Materials and Methods: Eighty-six patients with stage IIIC to IV gastric cancer were assessed for TP and DPD expression by immunohistochemistry. The association between CAPOX or SOX efficacy and TP/DPD expression was retrospectively analyzed. Results: There were no significant differences in the objective remission rate (ORR, 52.27% vs. 47.62%; P>0.05), disease control rate (72.73% vs. 73.81%, P>0.05), progression-free survival (hazard ratio [HR], 1.119; 95% confidence interval [CI], 0.739–1.741; P=0.586), and overall survival (OS; HR, 0.855; 95% CI, 0.481–1.511; P=0.588) between CAPOX and SOX. A higher number of stage IV patients showed TP positivity, while DPD-positive patients predominantly showed intestinal type of gastric cancer. In TP-positive patients, the ORRs associated with CAPOX and SOX treatments were 57.14% and 38.10%, respectively; OS was better with CAPOX than with SOX (HR, 0.447; 95% CI, 0.179–0.978; P=0.046). Among DPD-positive patients, the SOX treatment-associated ORR (60.87%) was significantly higher than the CAPOX treatment-associated ORR (43.48%). Furthermore, SOX treatment resulted in better OS than did CAPOX treatment (HR, 2.020; 95% CI, 1.019–4.837; P=0.049). Conclusions: No significant difference in clinical efficacy was found between CAPOX and SOX. TP-positive patients might respond better to CAPOX while DPD-positive patients may respond better to SOX. Our findings might serve as a guide for personalized chemotherapy for gastric cancer.

OsBAK1 is involved in rice resistance to Xanthomonas oryzae pv. oryzae PXO99

Hualan Liao,Xiaorong Xiao,Xiuqiong Li,Yan Chen,Xiumei Fu,Daozhe Lin,Xiaolei Niu,Yinhua Chen,Chaozu He 한국식물생명공학회 2016 Plant biotechnology reports Vol.10 No.2

OsBAK1 gene belongs to a receptor like kinase gene family in rice and shares a highly conserved gene structure and sequence homology with Arabidopsis thaliana BAK1 gene. To investigate the role of OsBAK1 in rice immunity, the full-length cDNA of OsBAK1 was isolated by RT-PCR and the transgenic rice lines (over expression and RNA-interference lines) were generated using Agrobacterium-mediated transformation. The expression level of OsBAK1 was determined by q-PCR in overexpression and RNAi transgenic rice lines. Based on quantitative polymerase chain reaction (q-PCR) results, two overexpression lines and two RNAi lines were evaluated in bioassays for resistance to Xanthomonas oryzae pv. oryzae PXO99, the causal agent of rice bacterial blight disease. Pathogenicity bioassays showed overexpression OsBAK1 lines exhibited resistance to blight disease whereas OsBAK1 RNAi lines promoted susceptibility. Besides, OsBAK1 can complement the function of AtBAK1 in Arabidopsis bak1 protoplast, activating FRK1 expression, a marker gene in PTI signaling pathway, after treatment by flg22. Furthermore, the transcriptional level of OsBAK1 was induced significantly in rice by defense signaling molecules such as salicylic acid, jasmonic acid, and PXO99 inoculation. Our results illustrated OsBAK1 positively regulates plant defense against rice bacterium pathogen Xanthomonas oryzae pv. oryzae PXO99.

Solidification of uranium mill tailings by MBS-MICP and environmental implications

Niu Qianjin,Li Chunguang,Liu Zhenzhong,Li Yongmei,Meng Shuo,He Xinqi,Liu Xinfeng,Wang Wenji,He Meijiao,Yang Xiaolei,Liu Qi,Liu Longcheng 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.10

Uranium mill tailing ponds (UMTPs) are risk source of debris flow and a critical source of environmental U and Rn pollution. The technology of microbial induced calcium carbonate precipitation (MICP) has been extensively studied on reinforcement of UMTs, while little attention has been paid to the effects of MICP on U & Rn release, especially when incorporation of metakaolin and bacillus subtilis (MBS). In this study, the reinforcement and U & Rn immobilization role of MBS -MICP solidification in different grouting cycle for uranium mill tailings (UMTs) was comprehensively investigated. The results showed that under the action of about 166.7 g/L metakaolin and ~50% bacillus subtilis, the solidification cycle of MICP was shortened by 50%, the solidified bodies became brittle, and the axial stress increased by up to 7.9%, and U immobilization rates and Rn exhalation rates decrease by 12.6% and 0.8%, respectively. Therefore, the incorporation of MBS can enhance the triaxial compressive strength and improve the immobilization capacity of U and Rn of the UMTs bodies solidified during MICP, due to the reduction of pore volume and surface area, the formation of more crystals general gypsum and gismondine, as well as the enhancing of coprecipitation and encapsulation capacity