Entanglement Dynamics of Multipartite States under an XY Quantum-Critical Environment

Xiao San Ma,An Min Wang 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.55 No.6

By using negativity as an entanglement measure, we investigate the entanglement dynamics of multipartite quantum states under an XY quantum environment, which can exhibit a quantum phase transition. From the results, we find that the time evolution of multipartite quantum states depends not only on the size of the system and the quantum states of concern but also on the degrees of freedom of the environment, the anisotropy, and the transverse magnetic field of the environment. Especially, we find that the entanglement decay will be enhanced by the quantum phase transition of the environment under weak coupling. By using negativity as an entanglement measure, we investigate the entanglement dynamics of multipartite quantum states under an XY quantum environment, which can exhibit a quantum phase transition. From the results, we find that the time evolution of multipartite quantum states depends not only on the size of the system and the quantum states of concern but also on the degrees of freedom of the environment, the anisotropy, and the transverse magnetic field of the environment. Especially, we find that the entanglement decay will be enhanced by the quantum phase transition of the environment under weak coupling.

Experimental Study on the Performance of a Bidirectional Hybrid Piezoelectric-Hydraulic Actuator

Xiao Long Jin,Ngoc San Ha,Yong Zhe Li,Nam Seo Goo,Jangmi Woo,Han Seo Ko,Tae Heun Kim,Chang Seop Lee 한국항공우주학회 2015 International Journal of Aeronautical and Space Sc Vol.16 No.4

The piezoelectric-hydraulic actuator is a hybrid device that consists of a hydraulic pump driven by a piezo-stack coupled to a conventional hydraulic cylinder. The actuator is of compact size, but can produce a moderate energy output. Such hybrid actuators are currently being researched and developed in many industrialized countries due to the requirement for high performance and compact flight systems. In a previous study, we designed and manufactured a unidirectional hybrid actuator. However, the blocking force was not as high as expected. Therefore, in this study, we redesigned the pump chamber and hydraulic cylinder and also improved the system by removing the air bubbles. Two different types of piezo-stacks were used. In order to achieve bidirectional capabilities in the actuator, commercial solenoid valves were used to control the direction of the output cylinder. Experimental testing of the actuator in unidirectional and bidirectional modes was performed to examine performance issues related to driving frequency, bias pressure, reed valve thickness, etc. The results showed that the maximum blocking force was measured as 970.2N when the frequency was 185Hz.

Modulation Instability of an Intense Laser Beam in an Unmagnetized Plasma

San Qiu Liu,Wei Tang,Xiao Qing Li 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.4

The modulation instability of an intense elliptically polarized laser beam propagating in an unmagnetized plasma is investigated. Adopting a generalized Karpman method, a three-dimensional nonlinear equation is shown to govern the laser field. Conditions indicating the occurrence of modulation instability and its temporal growth rate, taking into account the longitudinal and the transverse perturbations, are obtained analytically, and the modulated growth rate is shown to be maximal for any fixed wave number when the initial laser field is coplanar with the perturbations. In the weakly relativistic region, the growth rate increases with increasing laser pump intensity and grows significantly when the laser approaches the critical surface.

Experimental Study on the Performance of a Bidirectional Hybrid Piezoelectric-Hydraulic Actuator

Jin, Xiao Long,Ha, Ngoc San,Li, Yong Zhe,Goo, Nam Seo,Woo, Jangmi,Ko, Han Seo,Kim, Tae Heun,Lee, Chang Seop The Korean Society for Aeronautical and Space Scie 2015 International Journal of Aeronautical and Space Sc Vol.16 No.4

The piezoelectric-hydraulic actuator is a hybrid device that consists of a hydraulic pump driven by a piezo-stack coupled to a conventional hydraulic cylinder. The actuator is of compact size, but can produce a moderate energy output. Such hybrid actuators are currently being researched and developed in many industrialized countries due to the requirement for high performance and compact flight systems. In a previous study, we designed and manufactured a unidirectional hybrid actuator. However, the blocking force was not as high as expected. Therefore, in this study, we redesigned the pump chamber and hydraulic cylinder and also improved the system by removing the air bubbles. Two different types of piezo-stacks were used. In order to achieve bidirectional capabilities in the actuator, commercial solenoid valves were used to control the direction of the output cylinder. Experimental testing of the actuator in unidirectional and bidirectional modes was performed to examine performance issues related to driving frequency, bias pressure, reed valve thickness, etc. The results showed that the maximum blocking force was measured as 970.2N when the frequency was 185Hz.

Identification of Homer1 as a Potential Prognostic Marker for Intrahepatic Cholangiocarcinoma

Wu, San-Yun,Yu, Ming-Xia,Li, Xiao-Gai,Xu, Shu-Fang,Shen, Ji,Sun, Zhen,Zhou, Xin,Chen, Xing-Zhen,Tu, Jian-Cheng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

Background: The aim of the present study was to analyze whether Homer1 is a potential prognostic marker for intrahepatic cholangiocarcinoma (ICC). Materials and Methods: The expression of Homer1 in ICC tissue was detected with immunohistochemistry and levels of protein in ICC and paratumor tissues were evaluated by Western blotting. Survival analysis by the Kaplan-Meier method was performed to assess prognostic significance. Results: Homer1 expression was high in 67.4% (58/86) of ICC samples, and there was significant difference between ICC and adjacent noncancerous tissues (p<0.001); high expression was associated with poor histologic differentiation (p=0.019), TNM stage (p=0.014), lymph node metastasis (p=0.040), and lymphatic invasion (p=0.025). On Kaplan-Meier analysis, a comparison of survival curves of low versus high expressors of Homer1 revealed a highly significant difference in OS (p=0.001) and DFS (p=0.006), indicating that high expression of Homer1 was linked with a worse prognosis. Multivariate analyses showed that Homer1 expression was an independent risk factor predicting overall survival[Hazard ratio(HR), 7.52; 95% confidence interval (CI), 2.63-21.47; p=0.002] and disease-free survival (HR, 11.56; 95%CI, 5.17-25.96; p<0.001) in ICC. Conclusions: Homer1 promotes lymphatic invasion and associates with lymph node metastasis and poor prognosis of ICC. The current study shows that Homer1 may be an independent prognostic factor for ICC patients after curative resection, and it provides an important basis for screening/treating high-risk patients.

Inhibitory effects of piceatannol on human cytomegalovirus (hCMV) in vitro

Wang San-Ying,Zhang Jing,Xu Xiao-Gang,Su Hui-Li,Xing Wen-Min,Zhang Zhong-Shan,Jin Wei-Hua,Dai Ji-Huan,Wang Ya-Zhen,He Xin-Yue,Sun Chuan,Yan Jing,Mao Gen-Xiang 한국미생물학회 2020 The journal of microbiology Vol.58 No.8

Human cytomegalovirus (hCMV) is a ubiquitous herpesvirus, which results in the establishment of a latent infection that persists throughout the life of the host and can be reactivated when the immunity is low. Currently, there is no vaccine for hCMV infection, and the licensed antiviral drugs mainly target the viral enzymes and have obvious adverse reactions. Thus, it is important to search for compounds with antihCMV properties. The present study aimed to investigate the suppressive effects of piceatannol on hCMV Towne strain infection and the putative underlying mechanisms using human diploid fibroblast WI-38 cells. Piceatannol supplementation prevented the lytic changes induced by hCMV infection in WI-38 cells. Furthermore, piceatannol suppressed the expression of hCMV immediate-early (IE) and early (E) proteins as well as the replication of hCMV DNA in a dose-dependent manner. Moreover, hCMV-induced cellular senescence was suppressed by piceatannol, as shown by a decline in the senescence-associated β-galactosidase (SA-β-Gal) activity and decreased production of intracellular reactive oxygen species (ROS). p16INK4a, a major senescence-associated molecule, was dramatically elevated by current hCMV infection that was attenuated by pre-incubation with piceatannol in a dose-dependent manner. These results demonstrated that piceatannol suppressed the hCMV infection via inhibition of the activation of p16INK4a and cellular senescence induced by hCMV. Together, these findings indicate piceatannol as a novel and potent anti-hCMV agent with the potential to be developed as an effective treatment for chronic hCMV infection.

Poster Session : Symposium: Soil Biology as a Catalyst for Bridging Production and Human Well-being ; Microcalorimetric Study of Changes in the Microbial Activity in Three Selected Vegetable Soil

Tida Ge,San`an Nie,G. Wang,D. Yang,H. Xiao,C. Tong,J. Wu 한국토양비료학회 2009 국제학술대회집 Vol.2009 No.0

Comparison of Hybridization Behavior between Double and Single Strand of Targets and the Application of Asymmetric PCR Targets in cDNA Microarray

( Qing Wei ),( San Zhen Liu ),( Jian Feng Huang ),( Xue Ying Mao ),( Xiao Hui Chu ),( Yu Wang ),( Min Yan Qiu ),( Yu Min Mao ),( Yi Xie ),( Yao Li ) 생화학분자생물학회 2004 BMB Reports Vol.37 No.4

Double stranded targets on the cDNA microarray contain representatives of both the coding and noncoding strands, which will introduce hybridization competition with probes. Here, the effect of double and single strands of targets on the signal intensity and the ratios of Cy5/Cy3 within the same slide were compared. The results show that single stranded targets can increase the hybridization efficiency without changing the Cy5/Cy3 ratio. Based on these results, a new strategy was established by generating cDNA targets with asymmetric PCR, instead of conventional PCR, to increase the sensitivity of the cDNA microarray. Furthermore, the feasibility of this approach was validated. The results indicate that the cDNA microarray system based on asymmetric PCR is more sensitive, with no decrease in the reliability and reproducibility as compared with that based on conventional symmetric PCR.

A clip domain serine protease stimulates melanization activation and expression of antimicrobial peptides in the Chinese oak silkworm, Antheraea pernyi

Lei Wang,Liu Yang,Xiao-San Zhou,Tao-Hong Li,Chao-Liang Liu 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.3

Clip domain serine proteases (Clips) mediate various biological processes, especially in insect immune responses such as prophenoloxidase (proPO) activation and Toll pathway initiation. In the present study, we cloned and studied the functions of a clip domain serine protease from Antheraea pernyi (ApSnake). ApSnake contains a typical clip domain and a trypsin-like serine protease domain. It shares high similarity with serine protease snake in Bombyx mori, and groups into the CLIPC family. ApSnake mRNA expressions were detected in all tested tissues, particularly high in the hemocytes. Challenged with four different microorganisms (Escherichia coli, Beauveria bassiana, Micrococcus luteus or Nuclear polyhedrosis virus), the expressions of ApSnake mRNA were induced significantly compared with control, particularly challenged by B. bassiana and M. luteus. Recombinant ApSnake protein stimulated melanization reaction and prophenoloxidase activation in A. pernyi hemolymph, but had no effect on phenoloxidase activity. Injection of recombinant ApSnake into A. pernyi larvae increased the transcript levels of proPO and antimicrobial peptides (AMPs) in hemocytes significantly. Our results suggested that ApSnake might be a modulating protein that both stimulate the melanization activation process and AMPs synthesis, and plays an important role in the innate immunity of A. pernyi.

Combination of canagliflozin and puerarin alleviates the lipotoxicity to diabetic kidney in mice

Qian Zhu,Qu Zhou,Xiao-li Luo,Xu-jie Zhang,San-yu Li 대한약리학회 2023 The Korean Journal of Physiology & Pharmacology Vol.27 No.3

Diabetic kidney disease is one of the most serious complications of diabetes. Although diabetic kidney disease can be effectively controlled through strict blood glucose management and corresponding symptomatic treatment, these therapies cannot reduce its incidence in diabetic patients. The sodium-glucose cotransporter 2 (SGLT2) inhibitors and the traditional Chinese herb “Gegen” have been widely used in diabetes-related therapy. However, it remains unclear whether the combined use of these two kinds of medicines contributes to an increased curative effect on diabetic kidney disease. In this study, we examined this issue by evaluating the efficacy of the combination of puerarin, an active ingredient of Gegen, and canagliflozin, an SGLT2 inhibitor for a 12-week intervention using a mouse model of diabetes. The results indicated that the combination of puerarin and canagliflozin was superior to canagliflozin alone in improving the metabolic and renal function parameters of diabetic mice. Our findings suggested that the renoprotective effect of combined puerarin and canagliflozin in diabetic mice was achieved by reducing renal lipid accumulation. This study provides a new strategy for the clinical prevention and treatment of diabetic kidney disease. The puerarin and SGLT2 inhibitor combination therapy at the initial stage of diabetes may effectively delay the occurrence of diabetic kidney injury, and significantly alleviate the burden of renal lipotoxicity