http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Kim, Sang-Tae,Lee, Seung-Yeon,Kim, Seung-Chul,Byun, Hye-Won,Lee, Sang-Tae,Kim, Mu-Yeal,Hong, Seok-Pyo,Chung, Young-Jae,Park, Ki-Ryong,Lee, Chung-Hee,Lee, Joong-Ku,Heo, Kyeong-In,Lee, Ji-Ye,Lee, Eun-Je National Science Museum of Korea 2011 Journal of Korean nature Vol.4 No.3
We developed the educational purpose mobile application, named "Wild Flowers of Bukhansan National Park (version 1.0)", aiming for easy identification of wild flowers for students and visitors in the park. When visitors find a flower or part of plant in the park, visitors can search for its name utilizing the pictures and characters provided in their own smartphone mobile devices or tablet PCs. The application provides pictures of wild flowers in the park and character-based searching system based on 12 diagnostic features (e.g., growth form, leaf arrangement, flower symmetry, petal color, petal number, sepal number, etc). We adopted the complete floristic survey of Chung and Lee (1962) and added species that we confirmed their distribution in the park during the development of this application. In summary, number of vascular plants in this park was estimated to be 428 taxa including 100 families, 280 genera, 327 species, 1 subspecies, 50 varieties, and 5 formas. We provided a total of 588 pictures representing 358 taxa and each taxon includes multiple pictures in many cases. Included identification quizzes can be an efficient educational tool as well as fun activity for students and visitors who are learning plant species in Korea. Our next step will include GPS function in the application for indicating visitor's location and for providing previously reported sites of the species that we interested in the map of the park. The future application which includes GPS function will be a valuable tool for the monitoring of rare plants, plant researches related to the climate changes, etc. We currently provide Korean iPhone version only, and English version and both of android versions will be serviced soon.
Determination of Boron Isotopic Ratio by Using an Alpha Track Technique
Park, Yong-Joon,Pyo, Hyung-Yeal,Song, Kyu-Seok,Song, Byoung-Chul,Jee, Kwang-Yong,Kim, Won-Ho Korean Chemical Society 2006 Bulletin of the Korean Chemical Society Vol.27 No.10
The determination of the boron isotopic ratio in solutions was achieved by means of a solid state track detector by using an alpha track. The neutron flux was optimized by using a Cd-foil to find the optimum conditions for counting the number of alpha tracks on the selected solid detector caused by the (n, $\alpha$) nuclear reaction of boron. The home-made multi-dot detector plate was utilized in this study to increase the reproducibility of the measurement by uniformly drying the boron solution within the marked circle area on the detector plate. The experimental results of this study verified that the $^{11}B/^{10}B $ isotopic ratio can be measured by observing the number of alpha tracks for different concentrated standard solutions with various isotopic compositions. This technique was applied to the determination of $^{10}B$ enrichment factor in a biological sample for a boron neutron capture therapy.
PRELIMINARY STUDY ON THE ALPHA TRACK ANALYSIS OF SPHERICAL URANIUM METAL PARTICLES
Pyo Hyung-Yeol,Kim Jong-Yun,Lee Myung-Ho,Park Yong-Jun,Jee Kwang-Yong,Kim Won-Ho Korean Nuclear Society 2006 Nuclear Engineering and Technology Vol.38 No.4
Alpha track analysis for the determination of the trace amount of alpha emitting nuclides in a very small particle was performed as an efficient and powerful technique during safeguard inspection. Metal particles with well-defined spherical shape, size and isotopic compositions as a reference material were used to correlate the number of tracks or track diameter with an isotopic composition eventually to identify the uranium enrichment in the environmental swipe samples. Slopes in the number of tracks versus the exposure time curve provide a simple insight into the uranium enrichment of an unknown particle. Low enriched uranium metal particles result in slopes still steeper than the depleted or natural uranium metal particles. In addition, a linear relationship between track diameter and particle size Is thought to be a useful first stage analytical tool as an efficient and convenient inspection guide. The significance of the simple linear model was also judged using the usual statistical tests.
( Won Hee Kim ),( Sung Pyo Hong ),( Chang Il Kwon ),( Kwang Hyun Ko ),( Pil Won Park ),( Ki Baik Hahm ),( Gwang Il Kim ),( Sei Kyung Chang ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Radiation proctitis is a common complication of radiation to lower abdomen and pelvis. Different modalities of treatment are available, however the effi cacy is incomplete. We hypothesized that human placenta and adipose-derived mesenchymal stem cells could have therapeutic potential on radiation proctitis. Methods: Placenta and adipose-derived mesenchymal stem cells were locally injected on distal rectal mucosa of female Sprague-Dawley rats within 24hrs of 25Gy rectal irradiation. 1,2,4 weeks later, they were sacrifi ced and the rectum was removed and blood sample was obtained to evaluate various parameters of infi ammation Results: Transplanted stem cell was identifi ed at rectal mucosa during 4 weeks after irradiation. Severe proctitis was provoked after pelvic irradiation refi ected with extensive infi ammatory cell infi ltration, loss of crypt epithelium and collagen deposition. However, treatment with mesenchymal stem cell restored these pathologic indices. In addition, mesenchymal stem cell had anti-infiammatory effect, anti- apoptotic effect. Regenerative property were increased. These effect was more prominent on adipose-derived mesenchymal stem cell. Conclusions: Placenta and adipose derived mesenchymal stem cell transplantation may be an potential therapeutic strategy to treatment of radiation proctitis.
Park, Seong Joon,Hong, Yong Sang,Lee, Jae-Lyun,Ryu, Min-Hee,Chang, Heung Moon,Kim, Kyu-pyo,Ahn, Yong Chel,Na, Young-Soon,Jin, Dong-Hoon,Yu, Chang Sik,Kim, Jin Cheon,Kang, Yoon-Koo,Kim, Tae Won S. Karger AG 2012 Oncology Vol.82 No.2
<P>Abstract</P><P><I>Objective:</I> The anti-epidermal growth factor receptor monoclonal antibody cetuximab has been shown to be effective in patients with wild-type<I> KRAS</I> metastatic colorectal cancer (mCRC). Fragment C γ receptor <I>(Fc</I>γ<I>R)</I> polymorphisms may predict the effectiveness of cetuximab, but this has not been established. This study investigated the clinical relevance of <I>Fc</I>γ<I>R</I> gene polymorphisms and <I>KRAS</I> status in iri-notecan-refractory mCRC patients treated with cetuximab. <I>Methods:</I> The total number of irinotecan-refractory mCRC patients studied was 118. Among them, 117 and 107 patients were screened for <I>KRAS</I> mutations and genetic polymorphisms of <I>Fc</I>γ<I>RIIa-131H/R</I> and <I>Fc</I>γ<I>RIIIa-158V/F</I>, respectively. The association of <I>Fc</I>γ<I>R </I>polymorphisms and<I> KRAS </I>mutations with clinical outcome was analyzed. <I>Results:</I><I>KRAS</I> mutations were found in 33 patients (27.1%). Wild-type <I>KRAS</I> was associated with a better response rate (p < 0.001), longer progression-free survival (p < 0.001) and longer overall survival (p < 0.001). <I>Fc</I>γ<I>RIIa H/H, H/R </I>and<I> R/R </I>polymorphisms were observed in 54, 49 and 4 patients, respectively, and <I>Fc</I>γ<I>RIIIa V/V, V/F </I>and <I>F/F </I>polymorphisms were observed in 6, 65, and 36 patients, respectively. Clinical outcomes were not significantly associated with either <I>Fc</I>γ<I>RIIa</I> or <I>Fc</I>γ<I>RIIIa</I> polymorphisms or with combinations of <I>KRAS </I>status and <I>Fc</I>γ<I>R </I>polymorphisms. <I>Conclusion:</I> The <I>Fc</I>γ<I>RIIa</I> and <I>Fc</I>γ<I>RIIIa</I> polymorphisms may not be useful molecular biomarkers for the activity of cetuximab in patients with mCRC.</P><P>Copyright © 2012 S. Karger AG, Basel</P>
Pyo, Se-Jeong,Song, Won-Wook,Kim, In-Ryoung,Park, Bong-Soo,Kim, Cheul-Hong,Shin, Sang-Hun,Chung, In-Kyo,Kim, Yong-Deok Baillière Tindall ; Springer London 2013 Lasers in medical science Vol.28 No.2
<P>The aim of this study was to examine the effect of low-level laser therapy (LLLT) on the cell viability and the expression of hypoxia-inducible factor-1s (HIF-1s), bone morphogenic protein-2 (BMP-2), osteocalcin, type I collagen, transforming growth factor-β1 (TGF-β1), and Akt in hypoxic-cultured human osteoblasts. Human fetal osteoblast cells (cell line 1.19) were cultured under 1?% oxygen tension for 72?h. Cell cultures were divided into two groups. At the experimental side, low-level laser (808?nm, GaAlAs diode) was applied at 0, 24, and 48?h. After irradiation, each cell culture was incubated 24?h more under hypoxia. Total energy was 1.2, 2.4, and 3.6?J/cm(2), respectively. Non-irradiated cultures served as controls. Comparisons between the two groups were analyzed by t test; a p value <0.05 was considered statistically significant. Hypoxia resulted in a decrease in the expression of type I collagen, osteocalcin, and TGF-β1 (p?<?0.001, p?<?0.001, and p?<?0.01, respectively). Cell viability and BMP-2 expression were not decreased by hypoxic condition. On the other hand, LLLT on hypoxic-cultured osteoblast promoted the expression of BMP-2, osteocalcin, and TGF-β1 (p?<?0.05, p?<?0.01, and p?<?0.001, respectively). Cell proliferation was also increased time-dependently. However, hypoxia decreased in type I collagen expression (p?<?0.001), and LLLT did not affect type I collagen expression in hypoxic-cultured osteoblasts. Furthermore, LLLT inhibited HIF-1 and Akt expression in hypoxic conditioned osteoblasts. We concluded that LLLT induces the expression of BMP-2, osteocalcin, and TGF- β1 in 1?% hypoxic-cultured human osteoblasts.</P>
Park, Yong-Joon,Pyo, Hyung-Ryul,Kim, Ji-Young,Kim, Won-Ho Korean Nuclear Society 1998 Nuclear Engineering and Technology Vol.30 No.6
A natural analogue study has been performed for the Koongarra uranium ore deposit in Australia as an international agreement of the Analogue Studies in the Alligator Rivers Region (ASARR). Rocks obtained from the Koongarra deposit, Northern Territory of Australia, were examined in order to understand uranium migration processes of primary and secondary ore-body in both weathered and unweathered zones. Total alpha activities of rock samples were measured to compare the relative amount of uranium in the sample. Uranium distributions have been investigated by means of both the alpha-autoradiography and the fission track registration technique after irradiation in a flux of thermal neutrons (~10$\times$$10^{13}$nㆍ$cm^{-2}$ㆍs$^{-1}$) for 2 minutes. The mineral phases corresponding to the registered alpha-tracks and fission tracks were identified by petrological observation with optical microscope as well as X-ray diffraction and electron microprobe analysis (EPMA). Uranium was found mostly inside of the fracture of the quartzite and its mineral phase was identified as sklodowskite. The mineral phase associated with high uranium concentration was found as illeminite by petrological observation with optical microscope as well as EPMA.
Park, Yong-Joon,Pyo, Hyung-Ryul,Kim, Do-Yang,Jee, Kwang-Yong,Kim, Won-Ho Korean Nuclear Society 2000 Nuclear Engineering and Technology Vol.32 No.5
The mechanism of corrosion behavior has to be understood clearly to select an optimum material for handling molten salts to be used in the oxide reduction process of PWR spent fuel. In this study, the oxidation states of corrosion products on the surface of Inconel 600 and 800H as well as their chemical compositions and structural informations were determined by using XPS, ICP-AES, AAS, EPMA and XRD after the corrosion experiment with lithium molten salts at 75$0^{\circ}C$ for 25 hours. Nickel and oxygen were detected from the corrosion products on the surface of Inconel plates and chromium was found to be dissolved out into lithium molten salts leaving cracks on the surface. The corrosion products were identified as metal oxides such as Fe$_2$O$_3$, Cr$_2$O$_3$, NiO, NiFe$_2$O$_4$and MnO by using XPS and XRD.
Performance Analysis for Mirrors of 30 cm Cryogenic Space Infrared Telescope
Park, Kwi-Jong,Moon, Bong-Kon,Lee, Dae-Hee,Jeong, Woong-Seob,Nam, Uk-Won,Park, Young-Sik,Pyo, Jeong-Hyun,Han, Won-Yong 한국우주과학회 2012 Journal of Astronomy and Space Sciences Vol.29 No.3
We have designed a 30 cm cryogenic space infrared telescope for astronomical observation. The telescope is designed to observe in the wavelength range of 0.5~2.1 μm, when it is cooled down to 77 K. The result of the preliminary design of the support structure and support method of the mirror of a 30 cm cryogenic space infrared telescope is shown in this paper. As a Cassegrain prescription, the optical system of a 30 cm cryogenic space infrared telescope has a focal ratio of f/3.1 with a 300 mm primary mirror (M-1) and 113 mm secondary mirror (M-2). The material of the whole structure including mirrors is aluminum alloy (Al6061-T6). Flexures that can withstand random vibration were designed, and it was validated through opto-mechanical analysis that both primary and secondary mirrors, which are assembled in the support structure, meet the requirement of root mean square wavefront error <λ/8 for all gravity direction. Additionally, when the M-1 and flexures are assembled by bolts, the effect of thermal stress occurring from a stainless steel bolt when cooled and bolt torque on the M-1 was analyzed.