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Hélène Caillon,Cécile Tardif,Erwan Dumontet,Norbert Winer,Damien Masson 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.2
Background: Management of pregnant women at high risk of pre-eclampsia (PE) requires frequent monitoring, with referral to specialized perinatal care centers. Reliable tests are necessary to improve prediction of PE and related complications and to assess disease severity and progression. An imbalance in two biomarkers, soluble fms-like tyrosine kinase 1 (sFlt-1) and placental growth factor (PlGF), is involved in PE pathogenesis. The sFlt-1 to PlGF ratio is increased in pregnant women before the onset of PE. An elevated ratio is highly predictive of PE, whereas the diagnosis of PE can be ruled out within one week for low ratios. The main objective of this study was to assess whether a low sFlt-1/PlGF ratio, below a cutoff of 38, can predict the absence of PE within one week.
Calculation of EHL Traction for a Model Hydrocarbon Using Molecular Simulation and Rheometry
Scott Bair,Clare McCabe,Peter T. Cummings,Ward O. Winer 한국트라이볼로지학회 2002 한국트라이볼로지학회 학술대회 Vol.2002 No.10
Recently, remarkable agreement has been reported between nonequilibrium molecular dynamics simulation and high-pressure Couette rheometry on squalane. We utilized the parameters obtained from this unique collaboration along with high-pressure viscometer measurements to calculate the elastohydrodynamic traction curve. A comparison with measured traction at 1.29 ㎬ shows excellent agreement, confirming the validity of the measurements and simulations. It should no longer be necessary to invoke a different rheological response to explain film thickness and traction.
Choi, W.,Ranasinghe, D.,Bunavage, K.,DeShazo, J.R.,Wu, L.,Seguel, R.,Winer, A.M.,Paulson, S.E. Elsevier Pub.Co 2016 The Science of the total environment Vol.553 No.-
This study attempts to explain explicitly the direct and quantitative effects of complicated urban built-environment on near-road dispersion and levels of vehicular emissions at the scale of several city blocks, based on ultrafine particle concentrations ([UFP]). On short timescales, ultrafine particles are an excellent proxy for other roadway emissions. Five measurement sites in the greater Los Angeles with different built environments but similar mesoscale meteorology were explored. After controlling for traffic, for most sampling days and sites, morning [UFP] were higher than those in the afternoon due to limited dispersion capacity combined with a relatively stable surface layer. [UFP] at the intersection corners were also higher than those over the sampling sites, implying that accelerating vehicles around the intersections contributed to [UFP] elevation. In the calm morning, the areal aspect ratio (Ar<SUB>area</SUB>), developed in this study for real urban configurations, showed a strong relationship with block-scale [UFP]. Ar<SUB>area</SUB> includes the building area-weighted building height, the amount of open space, and the building footprint. In the afternoon, however, when wind speeds were generally higher and turbulence was stronger, vertical turbulence intensity σ<SUB>w</SUB> was the most effective factor controlling [UFP]. The surrounding built environment appears to play an indirect role in observed [UFP], by affecting surface level micrometeorology. The effects are substantial; controlling for traffic, differences in Ar<SUB>area</SUB> and building heterogeneity were related to differences in [UFP] of factors of two to three among our five study sites. These results have significant implications for pedestrian exposure as well as transit-oriented urban planning.