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Weicai Wu,Leijing Liu,Yinhua Zhou,Shanpeng Wen,Wenjing Tian 한국물리학회 2009 Current Applied Physics Vol.9 No.5
The influence of two components blend ratio, solution concentration and thermal annealing on the morphology of poly(2-methoxy-5-(2'-ethyl-hexyloxy)-p-phenylenevinylene) (MEH-PPV): N,N'-bis(1-ethylpropyl)-3,4:9,10-perylene bis(tetracarboxyl diimide) (EP-PTC) blend films spin-cast from chloroform solutions has been studied using atomic force microscopy (AFM). The AFM images show that the dimension of the phase separation increases with the EP-PTC content and total solution concentration. When the annealing temperature increases from 90 to 150 ℃, the EP-PTC crystal-like clusters grow rapidly. Solar cells based on MEH-PPV:EP-PTC blend films with different weight ratios were fabricated. The device with 1:3 weight ratio has a higher power conversion efficiency (PCE) of 0.072% compared with the devices with 1:1, 1:2 and 1:4 ratio, which increases by about 14 times over that of the device with 1:1 ratio that has a PCE of 0.005%. It is indicated that the optimum performance of the photovoltaic device is strongly related to the finer phase separation between MEH-PPV and EP-PTC on a submicron scale which enables an efficient dissociation of photogenerated excitons, and the pure EP-PTC phase can build up a percolating network with pathways large enough to enhance electron transport.
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Jingsong He,Ni Xie,Jianbo Yang,Hong Guan,Weicai Chen,Huisheng Wu,Zishan Yuan,Kun Wang,Guojin Li,Jie Sun,Limin Yu 한국유방암학회 2014 Journal of breast cancer Vol.17 No.3
Purpose: Synuclein-γ (SNCG), which was initially identified asbreast cancer specific gene 1, is highly expressed in advancedbreast cancers, but not in normal or benign breast tissue. Thisstudy aimed to evaluate the effects of SNCG siRNA-treatmenton breast cancer cells and elucidate the associated mechanisms. Methods: Vectors containing SNCG and negative control(NC) siRNAs were transfected into MDA-MB-231 cells; mRNAlevels were determined by real-time polymerase chain reaction. Cell proliferation was evaluated using the MTT assay, cell migrationwas assessed by the Transwell assay, apoptosis and cellcycle analyses were conducted with the flow cytometer, andWestern blot analysis was performed to determine the relativelevels of AKT, ERK, p-AKT, and p-ERK expression. Results:SNCG mRNA levels were significantly reduced in MDA-MB-231cells transfected with SNCG siRNA. Our results indicate that inSNCG siRNA-treated cells, cell migration and proliferation decreasedsignificantly, apoptosis was induced, and the cell cyclewas arrested. Western blot analysis indicated that the proteinlevels of p-AKT and p-ERK were much lower in the SNCG siRNA-treated groups, than in the control and NC groups. Conclusion:SNCG siRNA could decrease the migration and proliferationof breast cancer cells by downregulating the phosphorylationof AKT and ERK.
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