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Jia-rong Kan,Hui Jiang,Yu Tang,Dong-chun Wu,Yun-ya Wu,Jiang Wu 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2
A novel islanding detection method is proposed in this paper. It is based on a frequency drooping PLL, which was presented in a previous work. The cause of errors in the non-detection zone (NDZ) of conventional frequency disturbance islanding detection methods (IDM) is analyzed. A frequency drooping phase-locked-loop (FD-PLL) is introduced into a single-phase grid-connected inverter (SPGCI), which can guarantee that grid current is in phase with the grid voltage. A novel FD-PLL IDM is proposed by improving this PLL. In order to verify the performance of the proposed FD-PLL IDM, a full performance comparison between the proposed IDM and typical existing active frequency drift IDMs is carried out, which includes both dynamic performance and steady performance. With the same NDZ, the total harmonic distortion of the grid-current in the dynamic process and steady state is analyzed. The proposed FD-PLL IDM, regardless of the dynamic or steady process, has the best power quality. Experimental and simulation results verify that the proposed FD-PLL IDM has excellent performance.
DAB Converter Based on Unified High-Frequency Bipolar Buck-Boost Theory for Low Current Stress
Jia-rong Kan,Yao-dong Yang,Yu Tang,Dong-chun Wu,Yun-ya Wu,Jiang Wu 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2
This paper proposes a unified high-frequency bipolar buck-boost (UHFBB) control strategy for a dual-active-bridge (DAB), which is derived from the classical buck and boost DC/DC converter. It can achieve optimized current stress of the switches and soft switching in wider range. The UHFBB control strategy includes multi-control-variables, which can be achieved according to an algorithm derived from an accurate mathematical model. The design method for the parameters, such as the transformer turns ratio and the inductance, are shown. The current stress of the switches is analyzed for selecting an optimal inductor. The analysis is verified by the experimental results within a 500W prototype.
Kan, Jia-rong,Jiang, Hui,Tang, Yu,Wu, Dong-chun,Wu, Yun-ya,Wu, Jiang The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2
A novel islanding detection method is proposed in this paper. It is based on a frequency drooping PLL, which was presented in a previous work. The cause of errors in the non-detection zone (NDZ) of conventional frequency disturbance islanding detection methods (IDM) is analyzed. A frequency drooping phase-locked-loop (FD-PLL) is introduced into a single-phase grid-connected inverter (SPGCI), which can guarantee that grid current is in phase with the grid voltage. A novel FD-PLL IDM is proposed by improving this PLL. In order to verify the performance of the proposed FD-PLL IDM, a full performance comparison between the proposed IDM and typical existing active frequency drift IDMs is carried out, which includes both dynamic performance and steady performance. With the same NDZ, the total harmonic distortion of the grid-current in the dynamic process and steady state is analyzed. The proposed FD-PLL IDM, regardless of the dynamic or steady process, has the best power quality. Experimental and simulation results verify that the proposed FD-PLL IDM has excellent performance.
DAB Converter Based on Unified High-Frequency Bipolar Buck-Boost Theory for Low Current Stress
Kan, Jia-rong,Yang, Yao-dong,Tang, Yu,Wu, Dong-chun,Wu, Yun-ya,Wu, Jiang The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2
This paper proposes a unified high-frequency bipolar buck-boost (UHFBB) control strategy for a dual-active-bridge (DAB), which is derived from the classical buck and boost DC/DC converter. It can achieve optimized current stress of the switches and soft switching in wider range. The UHFBB control strategy includes multi-control-variables, which can be achieved according to an algorithm derived from an accurate mathematical model. The design method for the parameters, such as the transformer turns ratio and the inductance, are shown. The current stress of the switches is analyzed for selecting an optimal inductor. The analysis is verified by the experimental results within a 500W prototype.
( Rong Zhang ),( Yong Cui ),( Xi Zhang ),( Zhuo Yang ),( Yong Shan Zhao ),( Yong Bo Song ),( Chun Fu Wu ),( Jing Hai Zhang ) 생화학분자생물학회 (구 한국생화학분자생물학회) 2010 BMB Reports Vol.43 No.12
The existence of glycine residues in long-chain scorpion toxins has been well documented. However, their role as analgesics has not been evaluated. To address this issue, we investigated the functional role of glycines in the C-terminal end of Chinese-scorpion toxin from Buthus martensii Karsch (BmK AGP-SYPU2) using site-directed mutagenesis and analgesic activity assays. Recombinant BmK AGP-SYPU2 and its mutants were efficiently expressed in E. coli and purified to homogeneity using immobilized metal ion affinity chromatography (IMAC) and cation exchange chromatography. The mouse-twisting test was used to detect the analgesic activity of BmK AGP-SYPU2 and its mutants. As a result, we identified glycines at the C-terminal end that, when altered, significantly affected analgesic activity. Also, Mut6566 was significantly decreased compared to BmK AGP-SYPU2. These data indicate that the glycines at the C-terminal end are important for the analgesic activity of BmK AGP-SYPU2. [BMB reports 2010; 43(12): 801-806]
Rong-hua Pan,Feng-yan Xie,Hui-mei Chen,Li-zhi Xu,Xiao-chun Wu,Ling-ling Xu,Gang Yao 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.3
Salvianolic acid B (Sal B) is the most abundant bioactive molecule from Radix Salviae Miltiorrhizae, and has recently been used for treating renal fibrosis in traditional Chinese medicine. Here we investigated the ability reversal of Sal B to reverse the transdifferentiation of human kidney proximal tubular epithelial cells that was induced by transforming growth factor-beta 1 (TGF-β1). The effects of Sal B on HK-2 cell morphology were observed by phase contrast microscopy, while alpha smooth muscle actin and E-cadherin were studied by immunocytochemistry and real-time reverse transcription polymerase chain reaction, respectively. Exposure of HK-2 cells to TGF-β1 for 72 h induced a complete conversion of the epithelial cells to myofibroblasts. When HK-2 cells were co-incubated with Sal B and TGF-β1 for a further 72 h, the morphology of myofibroblasts returned to that of proximal tubular epithelial cells,whereas the myofibroblast phenotype was maintained after exposure of cells to TGF-β1 for 144 h. Sal B reduced alpha smooth muscle actin levels and increased E-cadherin levels compared with their epithelial-to-mesenchymal transition controls. The reversal effect of Sal B was dose-dependent. That Sal B reverses the epithelial-to-mesenchymal transition in vitro suggests that it could possibly facilitate the repair of tubular epithelial structures and the regression of renal fibrosis in injured kidneys.
Promoted Growth of Maize by the Phosphate Solubilizing Bacteria Isolated from North-east China
Wu, Hai-Yan,Wang, Li-Chun,Gao, Xing-Ai,Jin, Rong-De,Fan, Zuo-Wei,Kim, Kil-Yong,Zhao, Lan-Po Korean Society of Soil Science and Fertilizer 2011 한국토양비료학회지 Vol.44 No.1
A strain of phosphate solubilizing bacterium was isolated from rhizosphere and identified as Burkholderia sp. by 16S-rRNA gene sequence analyses. The bacterium was found to release gluconic acid and the solubilization of hydroxyapatite in the liquid medium by a significant drop in pH to 3.7 from an initial pH 7.0. The soluble-P concentration continuously increased during the incubation periods and the total amount of soluble P released in culture filtrate was detected at 990 mg $L^{-1}$ after 10 days of inoculation. Most promoted maize growth was found in the standard NPK (240-120-120 kg $ha^{-1}$) soil inoculation with Burkholderia sp. (Twenty milliliters/plant, 106 CFU) and also in the absence of Burkholderia sp. inoculation, the soil amended with only 2/3 levels of P gave significant higher plant yield compared to 1/3 levels of P or without P supplementation.
Chun Wu,Zhe Chen,Rong Qi,Ralph Kennel 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.4
To decouple the secondary saliencies in sensorless permanent magnet synchronous machine (PMSM) drives, a repetitive control (RC) in the angle domain is proposed. In this paper, the inductance model of a concentrated windings surface-mounted PMSM (cwSPMSM) with strong secondary saliencies is developed. Due to the secondary saliencies, the estimated position contains harmonic disturbances that are periodic relative to the angular position. Through a transformation from the time domain to the angle domain, these varying frequency disturbances can be treated as constant periodic disturbances. The proposed angle-domain RC is plugged into an existing phase-locked loop (PLL) and utilizes the error of the PLL to generate signals to suppress these periodic disturbances. A stability analysis and parameter design guidelines of the RC are addressed in detail. Finally, the proposed method is carried out on a cwSPMSM drive test-bench. The effectiveness and accuracy are verified by experimental results.
Tazarotene-Induced Gene 1 Interacts with DNAJC8 and Regulates Glycolysis in Cervical Cancer Cells
Chun-Hua Wang,Rong-Yaun Shyu,Chang-Chieh Wu,Mao-Liang Chen,Ming-Cheng Lee,Yi-Yin Lin,Lu-Kai Wang,Shun-Yuan Jiang,Fu-Ming Tsai 한국분자세포생물학회 2018 Molecules and cells Vol.41 No.6
The tazarotene-induced gene 1 (TIG1) protein is a retinoid-inducible growth regulator and is considered a tumor suppressor. Here, we show that DnaJ heat shock protein family member C8 (DNAJC8) is a TIG1 target that regulates glycolysis. Ectopic DNAJC8 expression induced the translocation of pyruvate kinase M2 (PKM2) into the nucleus, subsequently inducing glucose transporter 1 (GLUT1) expression to promote glucose uptake. Silencing either DNAJC8 or PKM2 alleviated the upregulation of GLUT1 expression and glucose uptake induced by ectopic DNAJC8 expression. TIG1 interacted with DNAJC8 in the cytosol, and this interaction completely blocked DNAJC8-mediated PKM2 translocation and inhibited glucose uptake. Furthermore, increased glycose uptake was observed in cells in which TIG1 was silenced. In conclusion, TIG1 acts as a pivotal repressor of DNAJC8 to enhance glucose uptake by partially regulating PKM2 translocation.