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      • Influence of Crystallite Size on Magnetocaloric Effect and Critical Behavior La<sub>0.7</sub>Sr<sub>0.3</sub>Mn<sub>0.92</sub>Co<sub>0.08</sub>O<sub>3</sub> Nanoparticles

        Tran Dang Thanh,Dinh Chi Linh,Le Viet Bau,Thi Anh Ho,Tien Van Manh,The-Long Phan,Seong-Cho Yu IEEE 2015 IEEE transactions on magnetics Vol.51 No.1

        <P>Four samples of La<SUB>0.7</SUB>Sr<SUB>0.3</SUB>Mn<SUB>0.92</SUB>Co<SUB>0.08</SUB>O<SUB>3</SUB> (LSMCO) with different crystallite sizes were prepared by the combination of solid-state reaction and mechanical milling methods. Based on isothermal magnetization data, M(H), temperature dependences of magnetic entropy change, ΔS<SUB>m</SUB>T, of the samples under a magnetic field change of 10 kOe were calculated. The maximum values of magnetic entropy change (|ΔS<SUB>max</SUB>|) at room temperature are in the range of 0.9-1.4 J · kg<SUP>-1</SUP> · K<SUP>-1</SUP>, corresponding to ferromagnetic (FM)-paramagnetic phase transition. In addition, M<SUP>2</SUP> versus H/M curves at temperatures around TC prove the samples exhibiting a second-order magnetic phase transition. The critical exponents β, γ, and δ were determined using the modified Arrott plot method and critical isotherm analysis. Here, these exponent values are located in between those expected for the mean-field theory and 3-D Heisenberg model. It means the coexistence of short-range and long-range FM interactions in LSMCO nanoparticles.</P>

      • Chemopreventive Effect of Curcuma comosa in a Mouse Model of Colitis-Associated Colorectal Cancer

        Van-Long Truong,Woo-Sik Jeong 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

        Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality worldwide and poses a serious threat to human health. Inflammation and gut microbial dysbiosis importantly contribute to initiation and progression of CRC. Chemoprevention is a potential strategy to reduce cancer-related mortality by blocking the initiation and/or suppressing the promotion of carcinogenesis. This study aimed to evaluate chemopreventive effects of Curcuma comosa ethanol extract (CCE) and its major compound 1.7-diphenyl (4E,6E)-4,6-heptadien-3-one (DPH) using a mouse model of AOM/DSS-induced CRC. CCE/DPH administration regained body weight and colon length in AOM/DSS-treated mice. Moreover, tumor number was reduced by CCE/DPH treatment. CCE/DPH also inhibited expression of colonic pro-inflammatory genes such as COX-2, IL-1β, IL-6, IL-17, IL-23 and TNF-α. Treatment of these compounds prevented CRC by improving gut microbial dysbiosis along with anti-inflammatory properties. Especially, CCE/DPH significantly increased the level of Lactobacillus reuteri, a probiotic bacterium. These findings suggest that CCE/DPH could be developed as chemopreventive agents for prevention of CRC.

      • KCI등재

        A Novel Hybrid Converter with Wide Range of Soft-Switching and No Circulating Current for On-Board Chargers of Electric Vehicles

        Van-Long Tran,Dai-Duong Tran,Van-Tuan Doan,Ki-Young Kim,Woojin Choi 대한전기학회 2018 Journal of Electrical Engineering & Technology Vol.13 No.1

        In this paper, a novel hybrid configuration combining a phase-shift full-bridge (PSFB) and a half-bridge resonant LLC converter is proposed for the On-Board Charger of Electric Vehicles (EVs). In the proposed converter, the PSFB converter shares the lagging-leg switches with half-bridge resonant converter to achieve the wide ZVS range for the switches and to improve the efficiency. The output voltage is modulated by the effective-duty-cycle of the PSFB converter. The proposed converter employs an active reset circuit composed of an active switch and a diode for the transformer which makes it possible to achieve zero circulating current and the soft switching characteristic of the primary switches and rectifier diodes regardless of the load, thereby making the converter highly efficient and eliminating the reverse recovery problem of the diodes. In addition an optimal power sharing strategy is proposed to meet the specification of the charger and to optimize the efficiency of the converter. The operation principle the proposed converter and design considerations for high efficiency are presented. A 6.6 kW prototype converter is fabricated and tested to evaluate its performance at different conditions. The peak efficiency achieved with the proposed converter is 97.7%.

      • KCI등재

        Optical Characterization of the PtSi/Si by Using Spectroscopic Ellipsometry

        Van Long Le,Tae Jung Kim,Han Gyeol Park,Hwa Seob Kim,Chang Hyun Yoo,Hyoung Uk Kim,김영동,Junsoo Kim,Sol Yee Im,Wonchul Choi,Seung Eon Moon,Eunsoo Nam 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.69 No.3

        We report an optical characterization of PtSi films for thermoelectric device applications which was done by using nondestructive spectroscopic ellipsometry (SE). A Pt monolayer and a Pt-Si multilayer which consisted of three pairs of Pt and Si layers were deposited on p-doped-silicon substrates by using sputtering method; then, rapid annealing process was done to form PtSi films through intermixing of Pt and Si atoms at the interface. Pseudodielectric function data < " > = < "1 > + i < "2 > for the PtSi/Si samples were obtained from 1.12 to 6.52 eV by using spectroscopic ellipsometry. Employing the Tauc-Lorentz and the Drude models, determined the dielectric function (") of the PtSi films. We found that the composition ratio of Pt:Si was nearly 1:1 for the PtSi monolayer and we observed transitions between occupied and unoccupied states in the Pt 5d states. We also observed the formation of PtSi layers in the Pt-Si multilayer sample. The SE results were confirmed by the transmission electron microscopy and energy dispersive X-ray spectroscopy.

      • KCI등재

        Chemopreventive Activity of Red Ginseng Oil in a Mouse Model of Azoxymethane/Dextran Sulfate Sodium-Induced Inflammation-Associated Colon Carcinogenesis

        Van-Long Truong,박민지,정우식 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.6

        Our previous studies have demonstrated antioxidant and cytoprotective properties of red ginseng oil (RGO). However, the role of RGO in models of intestinal inflammation has not been elucidated. In this study, we evaluated the chemopreventive effect of RGO in a mouse model of azoxymethane/dextran sulfate sodium (AOM/DSS)-induced colitis and explored its underlying mechanisms. Male C57BL/6 mice were intraperitoneally injected with a single dose of AOM (10 mg/kg), followed by 1.5% DSS in drinking water for 7 days to produce colon carcinogenesis. RGO at 10 or 100 mg/kg was orally given for 17 weeks. RGO supplementation reduced the plasma nitric oxide (NO) concentration as well as lipid peroxidation and inhibited the production of proinflammatory factors such as inducible NO synthase, cyclooxygenase-2, interleukin 1β, IL-6, and tumor necrosis factor-α in the mouse colitis tissue. Increased phosphorylation levels of p65 and IκB by AOM/DSS exposure were attenuated by the presence of RGO. In addition, RGO supplementation induced the activity of primary antioxidant enzymes such as superoxide dismutase and catalase as well as the expression of nuclear factor erythroid 2–related factor 2-mediated antioxidant enzyme hemeoxygenase-1 in the colons of AOM/DSS-treated mice. These findings indicate that RGO may be a potent natural chemopreventive agent for ameliorating inflammatory bowel diseases.

      • Antioxidant and Anti-inflammatory Effects of Extracts from Roots, Stems and Leaves of Polyscias fruticosa

        Van-Long Truong,Hanitranirina R. G. Rarison,Yun-Seo Kim,Seung-Ok Lee,Yeon-Ji Bae,Ji-Hong Bang,Woo-Sik Jeong 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

        Enhancement of antioxidant and anti-inflammatory functions is thought to be effective strategies for disease prevention. This study aimed to investigate antioxidant and anti-inflammatory effects of extracts from roots, stems, and leaves of Polyscias fruticosa. Results showed that P. fruticosa root, stem and leaf extracts and their fractions exhibited strong antioxidant activities, as evident from DPPH, ABTS<SUP>+</SUP>, NO radical scavenging activities. In addition, antioxidant activity was highly correlated with total phenolic, flavonoid, and saponin contents. Moreover, these extracts and their fractions significantly inhibited NO production and the expression of iNOS, COX-2, IL-1β in LPS-stimulated RAW 264.7 cells; among them, hexane fraction exhibited stronger antioxidant and anti-inflammatory effects than other fractions. P. fruticosa root, stem, and leaf extracts and their fractions also simultaneously suppressed the ROS formation and enhanced the expression of antioxidant enzyme HO-1 in LPS-stimulated macrophages. These results suggest that P. fruticosa could be a source of antioxidant and anti-inflammatory agents for prevention and/or treatment of pathological conditions.

      • Novel hybrid-blower-and-evaporator-assisted distillation for separation and purification in biorefineries

        Van Duc Long, Nguyen,Hong, Jimin,Nhien, Le Cao,Lee, Moonyong Elsevier 2018 Chemical engineering and processing Vol.123 No.-

        <P><B>Abstract</B></P> <P>The production of biofuels and biochemicals from biomass-based feedstock, which is one of the most promising strategies for replacing petroleum-based resources and thus alleviating global warming, has received increasing attention in recent years. However, this strategy is energy-intensive due to the low product concentrations after transformation step. In this study, a novel hybrid-blower-and-evaporator-assisted distillation configuration (HBED) was proposed for enhancing process efficiency in bioproduct production from biomass. Several important industrial cases have been investigated to demonstrate the proposed configuration. By applying HBED, light components are partially removed in an evaporator, and the latent heat can be circulated during the process, leading to a substantial improvement in energy efficiency. A blower can increase the energy efficiency of an evaporator significantly, while the combination of an evaporator and blower can substantially reduce the size, capital cost, and operating cost of the distillation column. The results show that the proposed HBED configuration can achieve significant energy savings. Notably, the operating costs can be reduced by up to 45.4%, 26.3%, and 36.7% for the levulinic acid, 2,3-butanediol, and furfural purification processes, respectively. Furthermore, the CO<SUB>2</SUB> emissions of a conventional column and the proposed configuration are evaluated and compared.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel hybrid-blower-and-evaporator-assisted distillation configurations were proposed. </LI> <LI> An evaporator can reduce the size, investment and operating costs of distillation. </LI> <LI> A blower can increase the energy efficiency of an evaporator significantly. </LI> <LI> The proposed configurations can handle large quantities of water and/or solvent. </LI> <LI> Substantial saving in operating cost could be achieved in biorefineries. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • Grid-search-and-box-search-assisted coordinate descent methodology for practical retrofit of the existing distillation columns to dividing wall columns

        Van Duc Long, Nguyen,Minh, Le Quang,Lee, Moonyong Elsevier 2018 Chemical engineering research & design Vol.131 No.-

        <P><B>Abstract</B></P> <P>A dividing-wall column (DWC) leading to savings in terms of substantial investment and operating costs, and a significant reduction in CO<SUB>2</SUB> emission constitutes an optimal solution for distillation process intensification. Recently, industrial applications of the DWC gradually increased although the need for an efficient, practical, and simple to implement optimization methodology persists. This study proposes a practical method that employs coordinate descent methodology, which is assisted by a grid search to avoid local optimal points and box searches to seek a more promising solution to optimize the retrofit of existing distillation columns to DWCs. The optimal DWC structure and operating conditions are determined in a practical and effective manner that is simple to implement and requires minimal simulation runs, which is suitable for industrial uses. The proposed method is examined in the optimal retrofit of a side stream column and a conventional two-column sequence that are widely used in the chemical process industry. The results show that the grid-search-and-box-search-assisted coordinate descent methodology combining mathematical programing techniques and statistical methods effectively avoids local optimal points but also corresponds to a more promising solution, and thus, it is competitive to coordinate descent methodology and response surface methodology that are popularly used in optimization processes in the chemical process industry. The retrofitted DWC systems lead to a substantial decrease in operating costs while effectively removing the bottleneck problem and mitigating CO<SUB>2</SUB> emission as well. Notably, operating costs are reduced to a maximum of 33.8% and 43.3% in retrofit of side stream columns and conventional two-column sequences, respectively. Both structural and operating variables are effectively and simultaneously optimized. It allows for the identification of interactions between design variables. Furthermore, the carbon dioxide emission is calculated and evaluated when retrofitting to the DWC.</P> <P><B>Highlights</B></P> <P> <UL> <LI> GSBSCD avoids the local optimal points and determines a more promising solution. </LI> <LI> GSBSCD combines mathematical programing techniques and statistical methods. </LI> <LI> The optimal DWC structure and operating conditions are found in a practical manner. </LI> <LI> GSBSCD allows the identification of interactions between the design variables. </LI> <LI> Substantial saving in operating cost could be achieved by using retrofitted DWC. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • SCISCIESCOPUS

        Improvement of the Deethanizing and Depropanizing Fractionation Steps in NGL Recovery Process Using Dividing Wall Column

        Long, Nguyen Van Duc,Lee, Moonyong The Society of Chemical Engineers, Japan 2012 Journal of chemical engineering of Japan Vol.45 No.4

        <P>In this work, our aim is to utilize a dividing wall column to improve the performance of the deethanizing and depropanizing fractionation steps in natural gas liquid processing. Starting from an initial conventional column sequence, the initial designs of the conventional dividing wall column and a top dividing wall column are obtained by maintaining the number of trays. In succession, they are optimized to reduce the energy consumption using factorial design. The results show that the conventional dividing wall column and the top dividing wall column can offer many benefits to the system, e.g., curbing the operating cost including refrigeration cost, and minimizing the reboiler and condenser duty. Furthermore, by using a dividing wall column, both the purity of ethane and its recovery rate are increased. The influence of utility prices on the operating cost saving of the conventional and the top dividing wall columns is also investigated. In addition, to further enhance the dividing wall column performance, heating is integrated on the top and an interreboiling system is installed at the bottom section of the dividing wall column.</P>

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