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V. S. MUTHUKUMAR,J. K. KIRAN,JASON REPPERT,R. SATYAJIT,VAMSI KRISHNA,G. NAGESHWAR RAO,S. SIVA RAMA KRISHNAN,S. SIVA SANKARA SAI,K. VENKATARAMANIAH,A. M. RAO 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2008 NANO Vol.3 No.3
Saturable absorbers and optical limiters have contrary optical transmission properties. We report observations of simultaneous occurrence of both these effects in a nickel sulphide nanoparticle (average dia. ~5 nm) solution and a simultaneous quantitative measurement of both. Intensity dependent nonlinear transmission studies carried out using a 7 ns Nd:YAG laser at 532 nm by the Z-scan method, revealed efficient optical limiting in nickel sulphide nanoparticle suspensions. Induced nonlinear optical scattering was identified to be the mechanism of optical limiting, and absorption at 532 nm was found to saturate. A modification of the conventional Z-scan implementation led to the retrieval of the saturation intensity which is otherwise overshadowed by very strong nonlinear scattering.
Durable keratin-based bilayered electrospun mats for wound closure
Singaravelu, Sivakumar,Ramanathan, Giriprasath,Muthukumar, Thangavelu,Raja, M. D.,Nagiah, Naveen,Thyagarajan, Sitalakshmi,Aravinthan, Adithan,P., Gunasekaran,Natarajan, T. S.,V. N. Geetha Selva, Ganga The Royal Society of Chemistry 2016 Journal of Materials Chemistry B Vol.4 No.22
<P>A bilayered nanofibrous scaffold with rapid wound healing properties is found to be suitable for tissue regeneration applications. The objective of this study is to reveal the fabrication of a poly(3-hydroxybutyric acid) (P)-gelatin (G) nanofibrous mat through electrospinning, with a horn keratin-chitosan-based biosheet (KC) as a bilayered nanofibrous scaffold. The mupirocin (D)-loaded horn KC biosheet (KCD) acts as the primary layer over which PG nanofibers were electrospun to act as the secondary layer. It is shown that this engineered bilayered nanofibrous scaffold material (KC-PG) should fulfill the functions of the extracellular matrix (ECM) by elucidating its function<I>in vitro</I>and<I>in vivo</I>. The bilayered nanofibrous scaffold was designed to exhibit improved physiochemical, biological and mechanical properties, with better swelling and porosity for enhanced oxygen permeability, and it also exhibits an acceptable antibacterial property to prevent infection at the wound site. The bilayered nanofibrous scaffold assists in better biocompatibility towards fibroblast and keratinocyte cell lines. The morphology of the nanofibrous scaffold aids increased cell adhesion and proliferation with cell material interactions. This was elucidated with the help of<I>in vitro</I>fluorescence staining against both cell lines. The bilayered KCD-PG nanofibrous scaffold material gives accelerated wound healing efficiency during<I>in vivo</I>wound healing. The results showed the regulation of growth factors with enhanced collagen synthesis, thereby helping in faster wound healing.</P>