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AEGIS: AN ADVANCED LATTICE PHYSICS CODE FOR LIGHT WATER REACTOR ANALYSES
Yamamoto, Akio,Endo, Tomohiro,Tabuchi, Masato,Sugimura, Naoki,Ushio, Tadashi,Mori, Masaaki,Tatsumi, Masahiro,Ohoka, Yasunori Korean Nuclear Society 2010 Nuclear Engineering and Technology Vol.42 No.5
AEGIS is a lattice physics code incorporating the latest advances in lattice physics computation, innovative calculation models and efficient numerical algorithms and is mainly used for light water reactor analyses. Though the primary objective of the AEGIS code is the preparation of a cross section set for SCOPE2 that is a three-dimensional pin-by-pin core analysis code, the AEGIS code can handle not only a fuel assembly but also multi-assemblies and a whole core geometry in two-dimensional geometry. The present paper summarizes the major calculation models and part of the verification/validation efforts related to the AEGIS code.
AEGIS: AN ADVANCED LATTICE PHYSICS CODE FOR LIGHTWATER REACTOR ANALYSES
AKIO YAMAMOTO,TOMOHIRO ENDO,MASATO TABUCHI,NAOKI SUGIMURA,TADASHI USHIO,MASAAKI MORI,MASAHIRO TATSUMI,YASUNORI OHOKA 한국원자력학회 2010 Nuclear Engineering and Technology Vol.42 No.5
AEGIS is a lattice physics code incorporating the latest advances in lattice physics computation, innovative calculationmodels and efficient numerical algorithms and is mainly used for light water reactor analyses. Though the primary objectiveof the AEGIS code is the preparation of a cross section set for SCOPE2 that is a three-dimensional pin-by-pin core analysiscode, the AEGIS code can handle not only a fuel assembly but also multi-assemblies and a whole core geometry in two-dimensional geometry. The present paper summarizes the major calculation models and part of the verification/validationefforts related to the AEGIS code.
Inhibitory Effect of Honeybee-Collected Pollen on Mast Cell Degranulation In Vivo and In Vitro
Yasuko Ishikawa,Tomoko Tokura,Nobuhiro Nakano,Mutsuko Hara,Fran?is Niyonsaba,Hiroko Ushio,Yuji Yamamoto,Tadahiro Tadokoro,Ko Okumura,Hideoki Ogawa 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.1
Bee-collected pollen (bee pollen [BP]) has been used as a folk medicine for centuries against various diseases,including allergy. There is no study elucidating how BP exerts such an anti-allergic effect. Since mast cells play a central rolein the pathogenesis of various allergic diseases, we investigated the effect of BP on mast cell activation elicited by the Fc im-munoglobulin E (IgE) receptor (Fc.RI)-mediated pathways. The in vivo effect of orally administered BP on cutaneous mastcell activation was examined by passive cutaneous anaphylaxis reaction. In vitromast cell degranulation and IgE binding tomast cells and the status of protein tyrosine phosphorylation were examined using bone marrow-derived mast cells. Daily oraladministration of BP to mice significantly reduced the cutaneous mast cell activation elicited by IgE and specific antigens.BP also reduced in vitromast cell degranulation and tumor necrosis factor-. production by inhibiting IgE binding to Fc.RIon mast cells. The inhibitory effect of BP on mast cell degranulation by preventing IgE binding was confirmed by the re-duced levels of protein tyrosine phosphorylation, which occurred as downstream events in activated mast cells via Fc.RI.These results first revealed that the anti-allergic action of BP was exerted by inhibiting the Fc.RI-mediated activation of mastcells, which plays important roles, not only in the early phase, but also in the late phase of allergic reactions.