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Burden of Healthcare Utilization Associated with Diabetes Mellitus in COVID-19 Infected Patients
( Md Azharuddin ),( Mohammad Adil ),( Upasna Gaba ),( Manju Sharma ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Purpose There available evidences of increased incidence and severity of COVID-19 in patients with diabetes mellitus (DM) reported with higher risk for intensive care unit (ICU) admission and substantial mortality. We carried out a systematic literature review and meta-analytic synthesis to find out the association between diabetes mellitus (DM) and related healthcare utilization burden in patients with COVID-19 infection. Methods We systematically searched MEDLINE, and Web of Science to identify studies investigating resource utilization of diabetic patients exposed to COVID-19. Meta-analysis was carried out using Review Manager 5.3. The random effects model was used to compute the pooled estimates of odds ratio/mean difference (OR)/(MD) and 95% confidence intervals (CI). Results Results from the pooled meta-analysis found that significant association was found between mortality and DM vs. nondiabetic [OR (95% CI): 2.46 (1.68, 3.58)]. ICU admission and use of mechanical ventilation were significantly associated with DM and COVID-19 vs. non-diabetic [OR (95% CI): 2.79 (1.79,4.34) and 3.33 (2.05, 5.42)], respectively. However, LOS, hospitalization, and ICU admission were not significantly different between patients with DM vs. non-DM. Conclusion The Results showed a significant association between mortality and DM exposed with COVID-19. Other co-morbidities especially CVD/hypertension could be a serious threat for DM COVID-19 infected patients for the higher mortality.
Genetic Variation and Phylogenetic Relationships of Indian Buffaloes of Uttar Pradesh
Joshi, Jyoti,Salar, R.K.,Banerjee, Priyanka,Upasna, S.,Tantia, M.S.,Vijh, R.K. Asian Australasian Association of Animal Productio 2013 Animal Bioscience Vol.26 No.9
India possesses a total buffalo population of 105 million out of which 26.1% inhabit Uttar Pradesh. The buffalo of Uttar Pradesh are described as nondescript or local buffaloes. Currently, there is no report about the genetic diversity, phylogenetic relationship and matrilineal genetic structure of these buffaloes. To determine the origin and genetic diversity of UP buffaloes, we sequenced and analysed the mitochondrial DNA D-loop sequences in 259 samples from entire Uttar Pradesh. One hundred nine haplotypes were identified in UP buffaloes that were defined by 96 polymorphic sites. We implemented neutrality tests to assess signatures of recent historical demographic events like Tajima's D test and Fu's Fs test. The phylogenetic studies revealed that there was no geographic differentiation and UP buffaloes had a single maternal lineage while buffaloes of Eastern UP were distinctive from rest of the UP buffaloes.