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( Muge Bilge ),( Zafer Unsal Coskun ),( Cengiz Cakan ),( Mine Adas ),( Serife Aysen Helvaci ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Warfarin is an anticoagulant used in a variety of clinical indications and may rarely cause severe bleeding that can be life-threatening.Although intramuscular bleeding frequently occure secondary to trauma,it can be induced in cases that cause bleeding tendency.Hematoma is often treated with conventional methods.However, surgical decompression can also be applied.Case Report;A 71 year old male patient admitted to our clinic with increased skin temperature, swelling and redness on the right leg.Warfarin was the only drug in the present treatment that cause bleeding tendency.During the physical examination, swelling, skin redness, echymosis, decreased motility, pain with palpation and tenderness were deteceted on the gastrocnemius location of the right leg.There was no other fi nding in the rest systemic examination.Magnetic resonance imaging (MRI) of the right lower limb of the patient showed a mass lesion on posteromedial of right cruris, displacing the medial head of the gastrocnemius muscle laterally(fig 1).Considering the datas of the performed imaging methods and using an ultrasonography-assisted GF-multipurpose drainage pigtale catheter,intracavitary administration of 5 mg tPA and 25 cc serum sale mixture was performed.Subsequently the catheter was clamped for a 25-30 minutes time and spontaneous drainage occured. After the intervention,a compression bandage was done with elastic bandage in order to avoid reloading of the cavity.Ultrasonographic control was performed after each step of the intervention to check a possible presence of an organised hematoma and intervention went on till there was no liquid rest in the location of hematoma. The total recovery was also proved by magnetic resonance imaging after total clinical recovery was deteceted (fig2).This case report represents that the addition of fi brinolytics to the standard drainage techniques is a safe and effective therapy method in organised hematoma as well as abscess complicated with surgery.
Baykara, Meltem,Buyukberber, Suleyman,Ozturk, Banu,Coskun, Ugur,Unsal, Diclehan Kilic,Demirci, Umut,Dane, Faysal,Kaplan, Muhammet Ali,Bora, Huseyin,Benekli, Mustafa Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4
Background: Chemoradiation (CRT) using cisplatin-based regimens has become the standard of care in the treatment of squamous cell head and neck cancers (SCHNC). The impact of taxanes as radiosensitizing agents with concurrent CRT regimens is unknown. We therefore retrospectively evaluated the efficacy and tolerability of a weekly cisplatin+docetaxel combination with CRT in locally advanced SCHNC. Methods: Sixty-six patients with locally advanced SCHNC (39.4% stage IV, 53% stage III, and 7.6% stage II) were assessed retrospectively. Total radiation dose to the PTV of gross disease (primary and/or node) was 70 Gy/35 fractions, 5 fractions per week. Minimum doses of 60 Gy and 50 Gy were administered to PTVs of elective high risk and low risk disease, respectively. Chemotherapy (CT) consisted of weekly cisplatin (20 $mg/m^2$)+docetaxel (20 $mg/m^2$) concurrently with RT. Results: The median age of the patients was 58 years (range, 32-77). Objective response rate was 83.3%. The 2-year progression-free survival (PFS) and overall survival (OS) were 75.7% and 78.3%, respectively. The most common grade 3 and 4 toxicities were mucositis (36.4%), nausea and vomiting (12.1%), neutropenia (4.5%). Conclusion: Weekly cisplatin and docetaxel concurrent with RT for locally advanced SCHNC was found tolerable with high efficacy.
Ugur Bozlar,Mehmet Sahin Ugurel,Bahri Ustunsoz,Unsal Coskun 대한영상의학회 2008 Korean Journal of Radiology Vol.9 No.5
Although the color Doppler ultrasonography diagnosis of intestinal malrotation with midgut volvulus, based on the typical “whirlpool” appearance of the mesenteric vascular structures is well-defined in the peer-reviewed literature, the combination of both the angiographic illustration of these findings and the contemporary state-of-the-art imaging techniques is lacking. We report the digital subtraction angiography and multidetector computed tomography angiography findings of a 37-year-old male with intestinal malrotation.