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- 저자 : Tse-Chuan (검색결과 4 건)
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Chang-Sheng Lin,Tse-Chuan Tseng 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.6
Modal Identification from response data only is studied for structural systems under nonstationary ambient vibration. The topic of thispaper is the estimation of modal parameters from nonstationary ambient vibration data by applying the random decrement algorithm withtime-varying threshold level. In the conventional random decrement algorithm, the threshold level for evaluating randomdec signatures isdefined as the standard deviation value of response data of the reference channel. The distortion of randomdec signatures may be, however,induced by the error involved in noise from the original response data in practice. To improve the accuracy of identification, amodification of the sampling procedure in random decrement algorithm is proposed for modal-parameter identification from the nonstationaryambient response data. The time-varying threshold level is presented for the acquisition of available sample time history to performaveraging analysis, and defined as the temporal root-mean-square function of structural response, which can appropriately describea wide variety of nonstationary behaviors in reality, such as the time-varying amplitude (variance) of a nonstationary process in a seismicrecord. Numerical simulations confirm the validity and robustness of the proposed modal-identification method from nonstationary ambientresponse data under noisy conditions.
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Ginsenoside Rg3 ameliorates allergic airway infl ammation and oxidative stress in mice
Wen-Chung Huang,Tse-Hung Huang,Kuo-Wei Yeh,Ya-Ling Chen,Szu-Chuan Shen,Chian-Jiun Liou 고려인삼학회 2021 Journal of Ginseng Research Vol.45 No.6
Background: Ginsenoside Rg3, isolated from Panax ginseng, has anti-inflammatory and anti-tumor activities. It is known to reduce inflammation in acute lung injury in mice, and to reduce the expression ofinflammatory cytokines and COX-2 in human asthmatic airway epithelium. In this study, we attemptedto determine whether ginsenoside Rg3 inhibits airway inflammation, oxidative stress, and airwayhyperresponsiveness (AHR) in the lungs of asthmatic mice. We also investigated its effects on oxidativestress and the inflammatory response in tracheal epithelial cells. Methods: Asthma symptoms were induced in female BALB/c mice sensitized with ovalbumin (OVA). Micewere divided into five groups: normal controls, OVA-induced asthmatic controls, and asthmatic micetreated with ginsenoside Rg3 or prednisolone by intraperitoneal injection. Inflammatory BEAS-2B cells(human tracheal epithelial cells) treated with ginsenoside Rg3 to investigate its effects on inflammatorycytokines and oxidative responses. Results: Ginsenoside Rg3 treatment significantly reduced eosinophil infiltration, oxidative responses,airway inflammation, and AHR in the lungs of asthmatic mice. Ginsenoside Rg3 reduced Th2 cytokineand chemokine levels in bronchoalveolar lavage fluids and lung. Inflammatory BEAS-2B cells treated withginsenoside Rg3 reduced the eotaxin and pro-inflammatory cytokine expressions, and monocyteadherence to BEAS-2B cells was significantly reduced as a result of decreased ICAM-1 expression. Furthermore, ginsenoside Rg3 reduced the expression of reactive oxygen species in inflammatory BEAS-2B cells. Conclusion: Ginsenoside Rg3 is a potential immunomodulator that can ameliorate pathological featuresof asthma by decreasing oxidative stress and inflammation
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Chen, Cai-Lun,Chou, Tse-Chuan 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1
Chloride ion sensor has a great deal of interest due to its importance in analyzing chloride ion in many areas, such as foods, drugs, biochemical studies and environmental pollution controls. The polyaniline modified carbon electrodes prepared by cyclic voltammograms with and without ultrasonic irradiation were used to detect chloride ion. The results showed that the response time, sensitivity and stability of chloride ion sensor prepared without ultrasonic irradiation were poor. On the other hand, the sensing characteristics of chloride ion sensor prepared with ultrasonic irradiation were good. The interference of other ions was also tested.
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Cheng, Fu-Yuan,Wan, Tien-Chun,Liu, Yu-Tse,Lai, Kung-Ming,Lin, Liang-Chuan,Sakata, Ryoichi Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.5
This study developed a natural ingredient as a functional food possessing properties of attenuation of hypertension and cardiovascular hypertrophy. In a previous study hydrolysates obtained from chicken leg bone protein using Alcalase strongly inhibited angiotensin I converting enzyme (ACE) in vitro. In particular, hydrolysate (A4H) from four hours of incubation exhibited the highest ACE inhibitory activity (IC50 = 0.545 mg/ml). A4H was selected as a potent ACE inhibitor and orally administrated to spontaneously hypertensive rats (SHR) for eight weeks to investigate attenuating effects on age-related development of hypertension and cardiovascular hypertrophy. Results showed that treatment with A4H of SHRs attenuated the development of hypertension as effectively as the clinical antihypertensive drug captopril. Moreover, a significantly lower heart to body weight ratio and thinness of coronary arterial wall was observed in SHRs that had been treated with A4H or captopril. The results suggest that A4H can be utilized in developing an ACE inhibitor as a potential ingredient of functional foods to alleviate hypertension and cardiovascular hypertrophy.
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