http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Trishna Debnath,Abul Hasnat,Mehnaz Pervin,이승연,박사라,김다혜,권혁중,김종문,임병우 한국식품과학회 2012 Food Science and Biotechnology Vol.21 No.5
The aim of this study was to evaluate the antiinflammatory activity of ethanol extracts from chaga mushroom (Inonotus obliquus, IOE) grown on germinated brown rice. A total of 35 male BALB/c mice were divided into 5 treatment groups and given a commercial diet (A),IOE administration (B), dextran sodium sulfate (DSS)treatment to induce colitis (C), IOE administration+DSSinduced colitis (D), and sulfasalazine administration+DSS-induced colitis (E). IOE treatment (D) decreased the expression of tumor necrosis factor (TNF)-α, cyclooxygenase (COX)-2, interleukin (IL)-4, interferon (IFN)-γ, signal transducers and activators of transcription (STAT)1, and STAT6 and showed lower levels of immunoglobulin (Ig)E and IgA in the spleen and mesenteric lymph node (MLN)compared to those of the DSS-induced colitis group (C). In addition, IOE suppressed the DSS-induced colonic tissue destruction. Therefore, our data strongly suggests that IOE could be a potent anti-inflammatory agent.
Nath, Narayan Chandra Deb,Debnath, Trishna,Kim, Eun-Kyung,Ali Shaikh, Md Aftab,Lee, Jae-Joon Elsevier 2018 ELECTROCHIMICA ACTA Vol.273 No.-
<P><B>Abstract</B></P> <P>Nanostructured copper–cobalt based spinel [(Cu<SUB>0.30</SUB>Co<SUB>0.70</SUB>)Co<SUB>2</SUB>O<SUB>4</SUB>] was employed as an electrocatalyst in the hydrogen peroxide (H<SUB>2</SUB>O<SUB>2</SUB>) reduction reaction (HRR). Both nanoparticles and nanoneedles co-existed in the (Cu<SUB>0.30</SUB>Co<SUB>0.70</SUB>)Co<SUB>2</SUB>O<SUB>4</SUB> spinel, which exhibited a high intrinsic electrical conductivity and surface-to-volume ratio, resulting therefore in a large electrochemically active surface area for the HRR. In addition, (Cu<SUB>0.30</SUB>Co<SUB>0.70</SUB>)Co<SUB>2</SUB>O<SUB>4</SUB> showed an onset potential at approximately −0.14 V in the HRR, with a limiting current density of ∼104 mA/cm<SUP>2</SUP> at −0.43 V. The synthesised material followed the direct HRR pathway and exhibited good stability. In addition, the HRR activity of (Cu<SUB>0.30</SUB>Co<SUB>0.70</SUB>)Co<SUB>2</SUB>O<SUB>4</SUB> was comparable to that of commercial Pt/C electrodes. The present results therefore demonstrate the significant potential of (Cu<SUB>0.30</SUB>Co<SUB>0.70</SUB>)Co<SUB>2</SUB>O<SUB>4</SUB> for future applications in fuel cells as a cathode catalyst.</P>
Choi, Eun-Ju,Debnath, Trishna,Tang, Yujiao,Ryu, Young-Bae,Moon, Sang-Ho,Kim, Eun-Kyung EDITIONS SCIENTIFIQUES ELSEVIER 2016 BIOMEDICINE AND PHARMACOTHERAPY Vol.84 No.-
<P><B>Abstract</B></P> <P><B>Background</B></P> <P> <I>Moringa oleifera</I> (<I>M. oleifera</I>) is widely cultivated in tropical and subtropical regions and has been used as a vegetable and in traditional medicine. In this study, the anti-atopic dermatitis activity of the ethanol extract of <I>M. oleifera</I> leaf was investigated <I>in vitro</I> and <I>in vivo.</I> </P> <P><B>Methods</B></P> <P>For the <I>in vitro</I> study, HaCaT human keratinocytes were used for cytokines and MAPKinase assay. In the <I>in vivo</I> study, <I>M. oleifera</I> leaf ethanolic extract (MO) was topically applied to BALB/c mice with <I>Dermatophagoides farinae</I> extract (DFE; house dust mite extract)- and 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis (AD).</P> <P><B>Results</B></P> <P>The expression of TNF-α, CCL17, IL-1β, IL-6 pro-inflammatory cytokine-related mRNA, and mitogen-activated protein kinases (MAPKs) in TNF-α/IFN-γ-induced HaCaT keratinocytes were reduced by MO. Epidermal and dermal ear thickness, mast cell infiltration, serum immunoglobulin levels, as well as gene expression of various cytokines in the ear tissue, lymph nodes, and splenocytes were improved by treatment with MO. In addition, MO reduced the expression of retinoic acid-related orphan receptor γT (RORγT), thymic stromal lymphopoietin (TSLP), and mannose receptor (CD206) mRNA in the ear tissue and improved cervical lymph node size.</P> <P><B>Conclusion</B></P> <P>The results of this study strongly suggest the beneficial effects of MO on AD via the regulation of inflammatory responses.</P>