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      • SCIESCOPUSKCI등재

        Gender-Related Differences in a Process of the Age-Dependent Alterations of the Elements in Monkey Sino-Atrial Node

        Satoh, Hiroyasu,Tohno, Setsuko,Minami, Takeshi,Oishi, Takao,Hayashi, Motoharu,Tohno, Yoshiyuki The Korean Society of Pharmacology 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.5

        Gender differences in the trace elements of monkey sino-atrial (SA) node were investigated in a process of age-dependent alterations. Sixty hearts from Japanese and rhesus monkeys (30 male and 30 female) used were aged ranging from 1-day- to 30-year-old. The elements were analyzed using an inductively coupled plasma-atomic emission spectrometer (ICP-AES). Advancing age decreased all the trace elements. Ca, P, S and Mg significantly decreased. The correlation coefficients of Ca and P were $-0.178{\pm}0.081$ (p<0.05) and $-0.088{\pm}0.022$ (p<0.05) in male (n=30), and $-0.095{\pm}0.026$ (p<0.05) and $-0.069{\pm}0.017$ (p<0.05) in female (n=30), respectively. The age-dependent coefficients for Fe/Ca, Zn/Ca, Fe/P, Fe/S, Zn/S, Fe/Mg and Zn/Mg were exhibited markedly in male, but all was less in female. In gender-related differences, only a ratio of P/Ca (p<0.05) was significantly observed with ageing. The trace elements such as Cu, Se and Sn were less detected in the SA nodes. These results indicate that the age-dependent changes in the ratios of elements are appeared more rapidly in male monkey SA node, and the gender difference is observed in ratio of P/Ca. The different attenuations may be involved with the age- and gender-related SA nodal functions.

      • KCI등재

        Gender-Related Differences in a Process of the Age-Dependent Alterations of the Elements in Monkey Sino-Atrial Node

        Hiroyasu Satoh,Setsuko Tohno,Takeshi Minami,Takao Oishi,Motoharu Hayashi,Yoshiyuki Tohno 대한약리학회 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.5

        Gender differences in the trace elements of monkey sino-atrial (SA) node were investigated in a process of age-dependent alterations. Sixty hearts from Japanese and rhesus monkeys (30 male and 30 female) used were aged ranging from 1-day- to 30-year-old. The elements were analyzed using an inductively coupled plasma-atomic emission spectrometer (ICP-AES). Advancing age decreased all the trace elements. Ca, P, S and Mg significantly decreased. The correlation coefficients of Ca and P were −0.178±0.081 (p< 0.05) and −0.088±0.022 (p< 0.05) in male (n=30), and −0.095±0.026 (p< 0.05) and −0.069±0.017 (p<0.05) in female (n=30), respectively. The age-dependent coefficients for Fe/Ca, Zn/Ca,Fe/P, Fe/S, Zn/S, Fe/Mg and Zn/Mg were exhibited markedly in male, but all was less in female. In gender-related differences, only a ratio of P/Ca (p<0.05) was significantly observed with ageing. The trace elements such as Cu, Se and Sn were less detected in the SA nodes. These results indicate that the age-dependent changes in the ratios of elements are appeared more rapidly in male monkey SA node, and the gender difference is observed in ratio of P/Ca. The different attenuations may be involved with the age- and gender-related SA nodal functions.

      • KCI등재

        An Experimental Estimation of Two Detection Limit Models

        Chang-Jin Ma(Chang-Jin Ma),Susumu Tohno(Susumu Tohno),Mikio Kasahara(Mikio Kasahara),Gong-Unn Kang(Gong-Unn Kang) 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.E1

        In environmental studies, decisions are often made on the analytical data indicating certain contaminants as being "detected" or "non-detectible." Since detection limits are analytical method specific, one has to first review the concepts and definitions associated with analytical method systems and specifications. In this study, the experimental analytical values for a series of low level standards (for an ionic species) were used as an example to estimate two different method detection limits (MDL). The scores of EPA's MOL and Pallesen's MDL determined by real analytical scores are 0.0575 and 0.0561 mg/L, respectively for our nitrate data. These scores determined by two different MDL models are roughly similar, while there are apparent differences between two methods with respect to statistical and systematical procedure. However, detennination of MDL for one's laboratory provides some practical applications which helps to assure one's regulating authorities that one's measured scores are accurate.

      • KCI등재

        Characteristics of Gas- and Particle-phase Acids and NH₃at Urban and Rural Sites in Korea

        Chang-Jin Ma(Chang-Jin Ma),Hui-Kang Kim(Hui-Kang Kim),Gong-Unn Kang(Gong-Unn Kang),Susumu Tohno(Susumu Tohno),Mikio Kasahara(Mikio Kasahara) 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.E1

        To study the characteristics of ammonia and the related compounds, atmospheric aerosols and gases were collected using a triple filter pack sampler, a low volume air sampler, and a three-stage Andersen air sampler in Seoul and Kangwha Island, Korea from Dec. 1996 to Oct. 1997. Ammonia concentrations showed approximately two times higher in summer than in winter at both sites. The highest HNO₃ levels were generally observed in summertime at two sampling sites. The average mass concentration of PM_2.5 in heavily industrialized Seoul was about three times higher than that of Kangwha. In winter, the sum of NH₄^+ and its counter ions (such as CI^-, NO₃^-, and S0₄²^-) comprised 30-41% of PM_2.5 mass concentration at each sampling site. Temperature dependence of particulate nitrate was examined at the urban sampling site. The formation of the nitrate in the fine mode was dependent not only on the amount of precursors but also on the variation of temperature. (NH₄)S0₄and NH₄HS0₄coexisted with NH₄NO₃and NH₄Cl at each site. According to the summertime backward trajectory analysis. NO₃- showed higher level with air parcels transported from northeast Asian continent. On the other hand, the concentration of SO₄²- showed significantly higher level when air masses originated from Pacific Ocean, southern part of Japan. and Korea.

      • KCI등재후보

        LCA를 통한 도시 고형 폐기물의 환경부하평가

        박정한,Tohno, Susumu,Kasahara, Mikio,이병인 한국환경과학회 2003 한국환경과학회지 Vol.12 No.6

        We analyzed the amount of environmental loads, and the amount of energy consumption through life cycle assessment from a discharge stage to the ultimate disposal to municipal solid waste in Seoul. We carried out inventory analysis of the amount of environmental loads that made the object range collection, intermediate treatment, and the final treatment, and took into consideration each stage exceptions CO₂ and NOx , the amount of SOx discharge, and energy consumption. We applied the data of an object model, and acquisition processed the scale of an object model suitably and applied to it to difficult data using the data of the Yokohama City incineration plant in Japan. The amount of environmental loads per lton of municipal waste were analyzed CO₂ 0.4C-ton, SOx 0.4㎏ and NOx 0.8㎏. Moreover, the amount of energy consumption which is 2.4Gcal was computed.

      • KCI등재후보

        Preliminary Study on the Visualization and Quantification of Elemental Compositions in Individual Microdroplets using Solidification and Synchrotron Radiation Techniques

        마창진,Susumu Tohno,Mikio Kasahara 한국대기환경학회 2011 Asian Journal of Atmospheric Environment (AJAE) Vol.5 No.1

        Quantifying the solute composition of a cloud droplet (or a whole droplet) is an important task for understanding formation processes and heating/cooling rates. In this study, a combination of droplet fixation and SR-XRF microprobe analysis was used to visualize and quantify elements in a micro-scale droplet. In this study, we report the preliminary outcome of this experiment. A spherical micro-scale droplet was successfully solidified through exposure to α-cyanoacrylate vapor without affecting its size or shape. An X-ray microprobe system equipped at the beam line 37XU of Super Photon ring 8 GeV (SPring-8)was applied to visualize and quantify the elemental composition in an individual micro-scale droplet. It was possible to reconstruct 2D elemental maps for the K and Cl contained in a microdroplet that was dispensed from the 10-ppm KCl standard solution. Multi-elemental peaks corresponding to X-ray energy were also successfully resolved. Further experiments to determine quantitative measures of elemental mass in individual droplets and high-resolution Xray microtomography (i.e., 3D elemental distribution)are planned for the future.

      • KCI등재

        Distribution and length of osteophytes in the lumbar vertebrae and risk of rupture of abdominal aortic aneurysms: a study of dry bones from Chiang Mai, Thailand

        Patcharin Chanapa,Tohno Yoshiyuki,Pasuk Mahakkanukrauh 대한해부학회 2014 Anatomy & Cell Biology Vol.47 No.3

        Vertebral osteophytes are a characteristic feature of intervertebral disc degeneration. In the lumbar spinal region, the two major structures in close proximity anterior to the spine are the inferior vena cava and the abdominal aorta, both of which have been reported to be affected by osteophytes. The purpose of this study was to determine the distribution, classification and lengths of osteophytes in the lumbar vertebrae. One hundred and eighty lumbar columns of 90 males and 90 females from Chiang Mai, Thailand, in the age range 15 to 96 years (mean age, 63 years) were collected. The measuring length of osteophytes was assessed on vertebral body and articular facet. Statistical analysis was performed by descriptive analysis, chi-square and Pearson Correlation. Lumbar osteophytes were presented in 175 specimens (97.2%), 88 males and 87 females. The highest frequency was at L4, most were on the superior, inferior surface of body and articular facet (39.7%, 38.4%, and 22%), respectively. The greatest mean length was 3.47±2.21 mm at L5, and the longest length of anterior superior surface of body was 28.56 mm. The osteophyte length was significantly correlated directly with age (P<0.01), and males were significantly greater than females (P<0.05). The highest prevalence of osteophytes was on the anterior side of superior surface of body (30.4%), and the classification was traction. It can be proposed that the abdominal aorta could be damaged, especially a risk of rupture of abdominal aortic aneurysm.

      • KCI등재

        Chemically Aged Asian Dust Particles Proven by Traditional Spot Test and the Most Advanced micro-PIXE

        마창진,Susumu Tohno,강공언 한국대기환경학회 2016 Asian Journal of Atmospheric Environment (AJAE) Vol.10 No.2

        A change in chemical compositions of Asian dust (AD) particles can dramatically alter their optical properties, cloud-forming properties, and health effects. The present study was undertaken to evaluate this aging of AD particles by means of two complementary methods (i.e., the traditional spot test and the most advanced micro-PIXE analytical technique) for single particle analysis. Size-classified particles were sampled at the rural peninsula of Korea (Byunsan, 35.37N; 126.27E) during AD event and non-AD period in 2004. Sulfate was principally enriched on the particles in the size range of 7.65-10.85 μm collected during AD event. The average number fraction of coarse particles (>2.05 μm) containing chloride was 16.2% during AD event. Relatively low particles containing nitrate compared to those containing sulfate and chloride were found in AD event. Micro-PIXE elemental maps indicated that a large number of AD particles were internally mixed with man-made zinc. The highest peaks of EC and OC concentrations were appeared at 0.01-0.43 μm particle aerodynamic diameter. High EC concentration in PM1 was might be caused by the Saemangeum Seawall Project that was being conducted during our field measurement.

      • Socio-technological impact analysis using an energy IO approach to GHG emissions issues in South Korea

        Chung, W.S.,Tohno, S.,Choi, K.H. Applied Science Publishers 2011 APPLIED ENERGY Vol.88 No.11

        Through energy input-output (E-IO) analyses from 1985 to 2005, the changes in three factors affecting GHG emissions in South Korea were analyzed. Based on the E-IO results, the changes in the direct and total (embodied) GHG emissions from the pertinent sectors were decomposed into three factors-the energy consumption effect, the social effect, and the technological effect-using the Sato-Vartia index for the three periods of 1985-1995, 1995-2000, and 2000-2005. The decomposition analysis demonstrated that a total emission matrix including both direct and indirect GHG emissions showed an evolution pattern that was very similar to the changes in direct GHG emissions; however, ripple effects were observed in the case of emissions from sector #-59 (Synthetic resins, synthetic rubber-p). The results showed that national energy policies such as those pertaining to the diversification of energy sources, shifts in the energy consumption structure (social effect), and the transformation to a low-carbon energy economy (technology effect) were effective. Finally, several limitations of the Divisia decomposition analysis were pointed out.

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