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RISS 인기검색어
- 검색키워드
- 저자 : Ting-Yen Hsieh (검색결과 4 건)
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Lan Ting-Yuan,Lin Yen-Chun,Tseng Tai-Chung,Yang Hung-Chih,Kao Jui-Hung,Cheng Chiao-Feng,Lee Tai-Ju,Huang Shang-Chin,Lu Cheng-Hsun,Li Ko-Jen,Hsieh Song-Chou 거트앤리버 소화기연관학회협의회 2023 Gut and Liver Vol.17 No.2
Background/Aims: Rituximab is known to be associated with high hepatitis B virus (HBV) reactivation rate in patients with resolved HBV infection and hematologic malignancy. However, data regarding HBV reactivation (HBVr) in rheumatic patients receiving rituximab is limited. To assess the HBVr rate in hepatitis B surface antigen (HBsAg)-negative patients receiving rituximab for autoimmune diseases in a large real-world cohort. Methods: From March 2006 to December 2019, 900 patients with negative HBsAg receiving at least one cycle of rituximab for autoimmune diseases in a tertiary medical center in Taiwan were retrospectively reviewed. Clinical outcome and factors associated with HBVr were analyzed. Results: After a median follow-up period of 3.3 years, 21 patients developed HBVr, among whom 17 patients were positive for hepatitis B core antibody (anti-HBc) and four were negative. Thirteen patients had clinical hepatitis flare, while eight patients had HBsAg seroreversion without hepatitis. Old age, anti-HBc positivity, undetectable serum hepatitis B surface antibody level at rituximab initiation and a higher average rituximab dose were associated with a higher HBVr rate. There was no significant difference in the HBVr risk between rheumatoid arthritis and other autoimmune diseases. Among anti-HBc-negative patients, subjects without HBV vaccination at birth had an increased risk of HBVr (4/368, 1.1%) compared with those who received vaccination (0/126, 0%). Conclusions: In HBV endemic areas where occult HBV is prevalent, anti-HBc-negative patients, may still be at risk for HBVr after rituximab exposure. HBVr may still be considered in HBsAgnegative patients developing abnormal liver function after rituximab exposure, even in patients with negative anti-HBc.
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Chun-yin Doris Chen,Ting-chi Rebecca Lin,Fang-Yen Hsieh 서울대학교 인지과학연구소 2023 Journal of Cognitive Science Vol.24 No.4
The present study investigated Chinese-speaking children’s interpretations of the simplex reflexive ziji and the complex reflexive taziji. The main issues addressed included the effect of non-structural information (i.e., verbal classification and noun prominence) on children’s interpretations of ziji and taziji. Apart from these factors, contextual effect was also considered. A yes/no judgment task was designed to elicit participants’ interpretations of ziji and taziji. The participants in the study consisted of sixty Chinese-speaking children who were divided into three experimental groups: G1 (kindergarteners aged five and six), G2 (second graders aged seven and eight), and G3 (fourth graders aged nine and ten). In addition, twenty Chinese-speaking adults were recruited as the control group. The major findings are summarized as follows: First, all three child groups preferred long-distance binding of ziji and taziji. The adult group showed no significant preference when interpreting ziji, but showed significant preference for local binding when interpreting taziji. Context affected the children’s interpretations of both reflexives. When context was provided, more long-distance interpretations were elicited, same for the adults. Second, verb types influenced the children’s interpretations. The children preferred the local interpretation with reflexive (zizhi) verbs and the long-distance interpretation with irreflexive (tazhi) verbs, same for the adults. Finally, NP prominence determined the children’s interpretations of ziji and taziji. The children preferred an agent or animate antecedent for reflexives, same for the adults.
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Multipoint Fuzzy Prediction for Load Forecasting in Green Buildings
Hsuan-Hao Chang,Wei-Yu Chiu,Ting-Yen Hsieh 제어로봇시스템학회 2016 제어로봇시스템학회 국제학술대회 논문집 Vol.2016 No.10
A novel load forecasting mechanism that uses fuzzy logic and big data, termed multipoint fuzzy prediction (MPFP), is proposed. The prediction mechanism is based on historical data and, therefore, is adaptive to dynamic changes over time when the database is updated properly. The MPFP can be combined with green buildings and renewable energy sources to reduce peak loads and energy consumption. An energy management system (EMS) can be integrated into the framework to achieve an improved level of performance. On the basis of a prediction of load curves, the EMS can discharge energy storage devices when electricity prices are high and charge them when electricity prices are low, reducing costs. Real power demand data were employed to illustrate the validity of the proposed MPFP scheme.
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Altered Auditory P300 Performance in Parents with Attention Deficit Hyperactivity Disorder Offspring
Mei Hung Chi,Ching-Lin Chu,I Hui Lee,Yi-Ting Hsieh,Ko Chin Chen,Po See Chen,Yen Kuang Yang 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.4
Objective: Altered event-related potential (ERP) performances have been noted in attention deficit hyperactivity disorder (ADHD) patients and reflect neurocognitive dysfunction. Whether these ERP alterations and correlated dysfunctions exist in healthy parents with ADHD offspring is worth exploring. Methods: Thirteen healthy parents with ADHD offspring and thirteen healthy controls matched for age, sex and years of education were recruited. The auditory oddball paradigm was used to evaluate the P300 wave complex of the ERP, and the Wechsler Adult Intelligence Scale-Revised, Wisconsin Card Sorting Test, and continuous performance test were used to measure neurocognitive performance. Results: Healthy parents with ADHD offspring had significantly longer auditory P300 latency at Fz than control group. However, no significant differences were found in cognitive performance. Conclusion: The presence of a subtle alteration in electro-neurophysiological activity without explicit neurocognitive dysfunction suggests potential candidate of biological marker for parents with ADHD offspring.
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