http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Ting-Hsing Chao (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Chien-Ning Hsu,Ya-Ting Lin,Yu-Hsu Chen,Tsung-Yu Tseng,Hsing-Fen Tsai,Shinn-Gwo Hong,Chao-Ling Yao 한국생물공학회 2023 Biotechnology and Bioprocess Engineering Vol.28 No.3
Repair and regeneration of vascular tissue is a crucial current research focus in the fields of biomedical engineering and regenerative medicine. Numerous studies revealed that cells are required to grow on an appropriate extracellular matrix to maintain or enhance functionality. In the present study, various surface modification methods were evaluated to fix fibronectin on the surface of a bio-based and aligned poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) film for vascular tissue engineering. After chemical modification, the properties of the fibronectin-fixed PHBV films were examined and compared with the original films, including -NH2 group expression, contact angle, mechanical properties, and fibronectin binding amount. Then, cytotoxicity and biocompatibility were measured by culture with L929 cells and endothelial progenitor cells (EPCs) of the fibronectinfixed PHBV films. In addition, cell morphology, cell growth kinetics, acetylated low-density lipoprotein uptake ability, lectin binding ability and specific gene expressions of cultured EPCs on fibronectin-fixed PHBV films were also analyzed. Taken together, our data demonstrated that the surface of the aligned PHBV films could be successfully modified to immobilize fibronectin. Importantly, EPCs cultured on the fibronectin-fixed PHBV films showed excellent cell biocompatibility, a rapid proliferation rate, an aligned growth direction and correct cell functions. We believed that fibronectin-fixed PHBV films can serve as a potential scaffold for vascular tissue engineering.
-
Relationship between the FRAX® score and falls in community-dwelling middle-aged and elderly people
Ling-Chun Ou,Yin-Fan Chang,Chin-Sung Chang,Ting-Hsing Chao,Ruey-Mo Lin,Zih-Jie Sun,Chih-Hsing Wu 대한골다공증학회 2016 Osteoporosis and Sarcopenia Vol.2 No.4
Objectives: Falls is a risk factor for fracture. The FRAX® predicts fractures. Whether the FRAX® is associated with fall in both gender is inconclusive. The aim of our study is to evaluate the association between FRAX scores and falls. Methods: The cross-sectional study set from 2009 to 2010 included 1200 community-dwelling people who were systematically sampled in central Taiwan. The 1200 participants (men: 524; women: 676; ?40 years old) completed questionnaires about socioeconomic status; lifestyle; medical and fall history were completed. FRAX scores with and without bone mineral density (BMD) were calculated by using the Taiwan calculator. Results: A total of 19.8% participants fell down. Binary regression models showed that diabetes mellitus history (OR: 1.61; 95% CI: 1.03e2.52), the FRAX without BMD in a continuous major score (OR: 1.06; 95% CI: 1.03e1.09), continuous hip score (OR: 1.11; 95% CI: 1.05e1.16), categorical major score ? 10% (OR: 1.81; 95% CI: 1.25e2.61), and categorical hip score ? 3% (OR: 1.80; 95% CI: 1.30e2.50) were independent risk factors for falls. FRAX with BMD in a continuous major score (OR: 1.04; 95% CI: 1.02e1.06), continuous hip score (OR: 1.06; 95% CI: 1.02e1.09), categorical major score ? 10% (OR: 1.52; 95% CI: 1.09e2.12), and categorical hip score ? 3% (OR: 1.53; 95% CI: 1.13e2.09) were also independent risk factors. Conclusions: We concluded that FRAX® scores with and without BMD were unanimously correlated with falls in community-dwelling middleaged and elderly males and females.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
