http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Thukham-mee Wipawee (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Laser Acupuncture Improves Memory Impairment in an Animal Model of Alzheimer’s Disease
Chatchada Sutalangka,Jintanaporn Wattanathorn,Supaporn Muchimapura,Wipawee Thukham-mee,Panakaporn Wannanon,Terdthai Tong-un 사단법인약침학회 2013 Journal of Acupuncture & Meridian Studies Vol.6 No.5
The burden of Alzheimer’s disease is continually rising globally, especially in the Asia-Pacific region. Unfortunately, the efficacy of the therapeutic strategy is still very limited. Because the effect of acupuncture at HT7 can improve learning and memory, the beneficial effect of laser acupuncture, a noninvasive form of acupuncture, at HT7 on memory improvement in patients with Alzheimer’s disease has been a focus of research. To elucidate this issue, we used AF64A, a cholinotoxin, to induce memory impairment in male Wistar rats, which weighed 180e220 g. Then, the animals were treated with laser acupuncture either at HT7 or at a sham acupoint once daily for 10 minutes for a period of 14 days. Spatial memory assessments were performed at 1, 7, and 14 days after AF64A administration and at the end of the experiment, and the changes in the malondialdehyde (MDA) level and in the superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), and acetylcholinesterase (AChE) activities in the hippocampus were recorded. The results showed that laser acupuncture significantly suppressed AChE activity in the hippocampus. Although laser acupuncture enhanced SOD and CAT activities, no reduction in MDA level in this area was observed. Therefore, laser acupuncture at HT7 is a potential strategy to attenuate memory impairment in patients with Alzheimer’s disease. However, further research, especially on the toxicity of laser acupuncture following repetitive exposure, is essential.
-
Rangseekajee Poonsri,Piyavhatkul Nawanant,Wattanathorn Jintanaporn,Thukham-mee Wipawee,Paholpak Pongsatorn 한국영양학회 2024 Nutrition Research and Practice Vol.18 No.1
BACKGROUND/OBJECTIVES Depression and anxiety are common mental health problems. Anthocyanins from berries might have an inhibitory effect on monoamine oxidase (MAO) enzymes and alleviate various mood and anxiety symptoms. This study examined the effects of a daily supplement of an anthocyanin-rich product on mental health problems. SUBJECTS/METHODS This study was a secondary analysis from a randomized, 6-week, open-label trial in 300 healthy participants aged 18–60 years who consumed 1 or 2 servings of anthocyanin-rich mulberry milk daily. The General Health Questionnaire-28 (GHQ-28) and Hospital Anxiety and Depression Scale (HADS) were used to monitor mental health problems. In addition, the saliva activity levels of MAO-A, MAO-B, and cortisol were examined at the baseline and after 6 weeks. RESULTS The total scores of the GHQ-28 and HADS and all their subscales decreased in both groups (all P < 0.05). The cortisol, MAO-A, and MAO-B activities decreased significantly (all P <0.05), but there were no significant differences between the groups (all P > 0.05). Significant correlations were noted between the decreased activity level of MAO-A enzyme and decreased scores from the GHQ-28 somatic subscale and the HADS depression subscale (all P < 0.05). CONCLUSIONS Daily consumption of anthocyanin-rich mulberry milk possibly improves mental health problems by reducing depressive and anxiety symptoms in the working population. The suppression of MAO-A activity is a possible underlying mechanism.
-
Jintanaporn Wattanathorn,Nattaporn Phunchago,Kowit Chaisiwamongkol,Supaporn Muchimapura,Wipawee Thukham-mee 사단법인약침학회 2015 Journal of Acupuncture & Meridian Studies Vol.8 No.1
Currently, the therapeutic strategy against memory deficit induced by alcoholism is not satisfactory and is expensive. Therefore, an effective, cheap strategy is required. On the basis of the memory-enhancing effect of stimulation of the HT7 acupoint, we aimed to determine whether acupuncture at the HT7 acupoint can reduce alcoholism-induced memory impairment. The possible underlying mechanism was also explored. Alcoholism was induced in male Wistar rats weighing 180-220 g. The alcoholic rats received either acupuncture at HT7 or sham acupuncture for 1 minute bilaterally once daily for 14 days. Their spatial memory was assessed after 1, 7 and 14 days of treatment. At the end of the study, the malondialdehyde (MDA) level and the activities of catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and acetylcholinesterase (AChE) enzymes in the hippocampus were determined using colorimetric assays. The results showed that acupuncture at HT7 significantly decreased the AChE activity and the MDA level, but increased the activities of CAT, SOD and GSH-Px in the hippocampus. These results suggest that acupuncture at HT7 can effectively reduce the alcoholism-induced memory deficit. However, further studies concerning the detailed relationships between the location of the HT7 acupoint and the changes in the observed parameters are required.
KCI
DBpia연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
