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Invited Mini Review : Phosphoinositide turnover in Toll-like receptor signaling and trafficking
( Oanh Thi Tu Le ),( Tu Thi Ngoc Nguyen ),( Sang Yoon Lee ) 생화학분자생물학회(구 한국생화학분자생물학회) 2014 BMB Reports Vol.47 No.7
Lipid components in biological membranes are essential for maintaining cellular function. Phosphoinositides, the phosphorylated derivatives of phosphatidylinositol (PI), regulate many critical cell processes involving membrane signaling, trafficking, and reorganization. Multiple metabolic pathways including phosphoinositide kinases and phosphatases and phospholipases tightly control spatio-temporal concentration of membrane phosphoinositides. Metabolizing enzymes responsible for PI 4,5-bisphosphate (PI(4,5)P2) production or degradation play a regulatory role in Toll-like receptor (TLR) signaling and trafficking. These enzymes include PI 4-phosphate 5-kinase, phosphatase and tensin homolog, PI 3-kinase, and phospholipase C. PI(4,5)P2 mediates the interaction with target cytosolic proteins to induce their membrane translocation, regulate vesicular trafficking, and serve as a precursor for other signaling lipids. TLR activation is important for the innate immune response and is implicated in diverse pathophysiological disorders. TLR signaling is controlled by specific interactions with distinct signaling and sorting adaptors. Importantly, TLR signaling machinery is differentially formed depending on a specific membrane compartment during signaling cascades. Although detailed mechanisms remain to be fully clarified, phosphoinositide metabolism is promising for a better understanding of such spatio-temporal regulation of TLR signaling and trafficking. [BMB Reports 2014; 47(7): 361-368]
Responsibility Accounting in Public Universities: A Case in Vietnam
LE, Oanh Thi Tu,BUI, Ngoc Thi Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.7
This study examines the current situation of responsibility accounting and proposed management solutions according to responsibility centers on public universities in Vietnam. The study applies quantitative research methods, and collected data through structured questionnaires to 138 public universities in Vietnam in 2019, receiving back 55 valid questionnaires. The data was cleaned and analyzed with SPSS software. The results show that most public universities in Vietnam assigned management responsibility to their departments, but responsibility accounting was not comprehensive since many universities are not financially autonomous. The Kruskal Wallis Test was conducted to compare the current situation of responsibility accounting among universities by the degree of autonomy and by geographic area. The research found out that totally autonomous universities assigned management responsibility to responsibility centers better than semi-autonomous and non-autonomous universities did. Regarding the evaluation of management responsibility, universities in Central Vietnam rated specific quantitative criteria, residual income (RI) and returns on investment (ROI) higher than universities in the North and the South of Vietnam did. However, universities in the South of Vietnam rated the evaluation of profits by department higher than the rest. The study also suggests structure for establishing responsibility centers in accordance with public universities in Vietnam.
DAO, Oanh Le Kieu,HO, Tuyen Thi Ngoc,LE, Hac Dinh,DUONG, Nga Quynh Korea Distribution Science Association 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.3
This study aims to investigate the impact of the multimarket contract on risk-adjusted profitability. Risk-adjusted profitability is measured in terms of risk-adjusted return on assets. This study employs dynamic panel data of 27 commercial banks in Vietnam using the GMM estimator to test the multimarket contact hypothesis in the Vietnamese banking sector. The results show that there is a negative impact of multimarket contact on the profitability of banks. Multimarket contact, deposit to asset ratio, non-interest income to total income, GDP growth rate, Worldwide Governance Indicator (WGI), and operating cost to assets are the major determinants of risk-adjusted profitability of commercial banks. Our main findings show that Vietnamese banks' focus to increase the multimarket contact may lead to lower profitability and there is evidence that supports theory predictions, since the average number of contacts among banks, bank size, and capitalization are positively related to risk-adjusted profitability. The study has policy implications for commercial banks in that they should not only focus on interest as a source of income and diversify their income source from non-interest income as well since it helps to improve risk-adjusted profitability for them.
Duong,Hoang Ngoc Khue,Nguyen,Thi Ngoc Oanh 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-
This purpose of the study is to evaluate the level of the environmental information disclosures by manufacturing firms which practices the annual reports in accordance with the circular 155/BTC, circular on guidelines for information disclosure on securities market. A model including 16 indexes based on the Circular 155/BTC was used to measure the level of environmental information disclosure. The study has been conducted on the sample of 40 manufacturing firms listed on HOSE and 120 annual reports from year 2014 to 2016 have been used for the study. The findings show that (i) There was an increase in the level of environmental disclosures from 2014 to 2016, and (ii) The extent of environment information disclosure in 2016 is just under average (36.87%). Through the findings several implications are suggested to enhance the level of the environmental information disclosure of firms listed on HOSE.
A research on students’ readiness for Education 4.0 program
Le Hoanh Su,Nguyen Thi Hong Linh,Vo Dang Hong Ngan,Le Kieu Oanh,Nguyen Ngoc Thanh,Tran Vuong Bao Tran ASCONS 2020 INTERNATIONAL JOURNAL OF EMERGING MULTIDISCIPLINAR Vol.4 No.1
Nowadays, in Vietnam, the government tends to have a great concern to the 4th Industrial Revolution, and Education 4.0 is also a matter to be paid attention to. In order to implement Education 4.0, besides technology and social, people are an important factor involved in the development of the education 4.0. The purpose of the study is to find out the factors affecting student readiness for education 4.0. The proposed model consists of 8 independent factors: Internet self-efficacy, Online communication self-efficacy, Self-regulation, Creativity, Self-discovery, Upgrade, Collaboration, Attitude and 1 dependent factor namely Readiness. Based on 361 samples, this quantitative research was conducted: reliability testing, exploratory factor analysis, correlation coefficients and linear regression. The result shows that there are four key factors affecting readiness including Self-regulation, Creativity, Upgrade and Attitude. The result of t-test shows that the group of students who had experienced online learning had higher readiness for the education 4.0 than the others.