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      • KCI등재

        Oil Cake 토양첨가에 의한 생강뿌리썩음병의 방제

        LAL THAKORE B.B.,SNEH MATHUR,R.B. SHINGH,B.P. CHAKRAVARTI 한국응용곤충학회 1987 한국응용곤충학회지 Vol.26 No.4

        토양에 첨가한 8종의 Oil cake 중 Margosa, Undi, Karanj cake은 생강뿌리썩음병의 발생을 억제하였다. 생강수량의 증진효과는 Karanj, Roselle, Mustard cake의 순으로 높았다. Out of 8 oil cakes used for soil amendment, Margosa, Undi and Karanj cakes were found to reduce the ginger rot. However, maximum increase in yield was found in Karanj cake followed by Roselle and Mustard cakes.

      • KCI등재

        단일살균제에 의한 땅콩 녹병과 검은무늬병의 관리

        B.B. LAL THAKORE,SNEH MATHUR,R.B. SINGH 한국응용곤충학회 1987 한국응용곤충학회지 Vol.26 No.2

        땅콩녹병과 검은 무늬병을 방제하기 위한 살균제를 선정하기 위하여 실내와 포장에서 실험한 결과 12개 공시약제중 Biloxazole이 상기 두 병해의 동시방제에 효과적이었으며 땅콩 수량도 증진되였다. Out of twelve fungicides evaluated in vitro and in vitro to manage rust and leaf spot diseases: Biloxazole was found to control both the diseases simultaneously and also increased the yield of peanut.

      • Soil Amendment wit Oil Cakes in Ginger Field for Rhizome Rot Control

        랄타코레,마투르,차크라바르티,Lal Thakore B.B.,Mathur Sneh,Singh R.B.,Chakravarti B.P. Korean Society of Applied Entomology 1987 한국식물보호학회지 Vol.26 No.4

        토양에 첨가한 8종의 Oil cake 중 Margosa, Undi, Karanj cake은 생강뿌리썩음병의 발생을 억제하였다. 생강수량의 증진효과는 Karanj, Roselle, Mustard cake의 순으로 높았다. Out of 8 oil cakes used for soil amendment, Margosa, Undi and Karanj cakes were found to reduce the ginger rot. However, maximum increase in yield was found in Karanj cake followed by Roselle and Mustard cakes.

      • KCI등재

        薄層 크로마토그라피와 指標 곰팡이의 利用에 의한 밀에 있어서 Triadimefon의 잔류량 분석

        KALPNA BHATNAGAR,B.B. LAL THAKORE,SNEH MATHUR,B.P. CHAKRAVARTI 한국응용곤충학회 1986 한국응용곤충학회지 Vol.25 No.4

        Macrophomina phaseolina균(菌)을 이용(利用)하여 살균제 Triadimefon의 밀 품종 Kharchia와 Lal Bahadur에 있어서 수확후의 잔류량을 조사한 결과 살포식물의 밀짚에서는 Triadimefon이 검출되었으나 밀 종자에서는 검출되지 않았다. 잔류량 조사를 위해 개발된 박층(薄層) 크로마토그라피에 의하여도 동일한 결과를 얻었다. 기주체내에서 Triadimefon은 Triadimenol로 전환되었다. By using the test fungus Macrophomina phaseolina, residues of triadimefon were found in straw collected after harvest from sprayed plants of wheat varieties Kharchia and Lal Bahadur but grains contain no such residues. Thin layer chromatographic method was developed to detect residues of the fungicide which was found to be present in straw of sprayed plants of both the varieties. No residues could be detected in grain samples. It was found that triadimefon was converted in triadimenol in/to host.

      • Search-Based Junit Test Case Generation of Code Using Object Instances and Genetic Algorithm

        Pranali Prakash Mahadik,D. M. Thakore 보안공학연구지원센터 2016 International Journal of Software Engineering and Vol.10 No.5

        To ensure software quality software testing is done .Test data generation is one of the more expensive parts of software testing. So, for reducing software cost and development time automation of test data generation is required. The object-oriented paradigm can be challenging for generating test data, due to some aspects of its features like abstract class, encapsulation, inheritance and visibility. To reach high code coverage of object oriented code search based test data generation technique is used. Proposed approach show that how efficiency and effectiveness of search based test data generation using static analysis. System takes input as different java class files then instances are generated for that classes then generate sequence of method call for whole code coverage then using genetic algorithm which is very useful and work efficiently when there is large search space it use to reach test target and finally generate test cases in Junit format which are helpful for all developers to perform unit testing.

      • Polymeric nanoparticles as dual-imaging probes for cancer management

        Menon, Jyothi U.,Jadeja, Parth,Tambe, Pranjali,Thakore, Dheeraj,Zhang, Shanrong,Takahashi, Masaya,Xie, Zhiwei,Yang, Jian,Nguyen, Kytai T. Techno-Press 2016 Biomaterials and Biomechanics in Bioengineering Vol.3 No.3

        This article reports the development of biodegradable photoluminescent polymer (BPLP)-based nanoparticles (NPs) incorporating either magnetic nanoparticles (BPLP-MNPs) or gadopentate dimeglumine (BPLP-Gd NPs), for cancer diagnosis and treatment. The aim of the study is to compare these nanoparticles in terms of their surface properties, fluorescence intensities, MR imaging capabilities, and in vitro characteristics to choose the most promising dual-imaging nanoprobe. Results indicate that BPLP-MNPs and BPLP-Gd NPs had a size of $195{\pm}43nm$ and $161{\pm}55nm$, respectively and showed good stability in DI water and 10% serum for 5 days. BPLP-Gd NPs showed similar fluorescence as the original BPLP materials under UV light, whereas BPLP-MNPs showed comparatively less fluorescence. VSM and MRI confirmed that the NPs retained their magnetic properties following encapsulation within BPLP. Further, in vitro studies using HPV-7 immortalized prostate epithelial cells and human dermal fibroblasts (HDFs) showed > 70% cell viability up to $100{\mu}g/ml$ NP concentration. Dose-dependent uptake of both types of NPs by PC3 and LNCaP prostate cancer cells was also observed. Thus, our results indicate that BPLP-Gd NPs would be more appropriate for use as a dual-imaging probe as the contrast agent does not mask the fluorescence of the polymer. Future studies would involve in vivo imaging following administration of BPLP-Gd NPs for biomedical applications including cancer detection.

      • KCI등재

        Rapid deployment of an emergency department-intensive care unit for the COVID-19 pandemic

        Sean Hickey,Kusum S. Mathews,Jennifer Siller,Judah Sueker,Mitali Thakore,Deepa Ravikumar,Ruben E Olmedo,Jolion McGreevy,Roopa Kohli-Seth,Brendan Carr,Evan S. Leibner 대한응급의학회 2020 Clinical and Experimental Emergency Medicine Vol.7 No.4

        The coronavirus disease 2019 (COVID-19) pandemic mandated rapid, flexible solutions to meet the anticipated surge in both patient acuity and volume. This paper describes one institution’s emergency department (ED) innovation at the center of the COVID-19 crisis, including the creation of a temporary ED–intensive care unit (ICU) and development of interdisciplinary COVID-19–specific care delivery models to care for critically ill patients. Mount Sinai Hospital, an urban quaternary academic medical center, had an existing five-bed resuscitation area insufficiently rescue due to its size and lack of negative pressure rooms. Within 1 week, the ED-based observation unit, which has four negative pressure rooms, was quickly converted into a COVID-19–specific unit, split between a 14-bed stepdown unit and a 13-bed ED-ICU unit. An increase in staffing for physicians, physician assistants, nurses, respiratory therapists, and medical technicians, as well as training in critical care protocols and procedures, was needed to ensure appropriate patient care. The transition of the ED to a COVID-19–specific unit with the inclusion of a temporary expanded ED-ICU at the beginning of the COVID-19 pandemic was a proactive solution to the growing challenges of surging patients, complexity, and extended boarding of critically ill patients in the ED. This pandemic underscores the importance of ED design innovation with flexible spacing, interdisciplinary collaborations on structure and services, and NP ventilation systems which will remain important moving forward.

      • Dendrite-like Process Formation and Cytoskeletal Remodeling Regulated by δ-Catenin expression

        Kim, Kwonseop,Sirota, Anna,Chen, Yan-hua,Jones, Shiloh B.,Dudek, Ronald,Lanford, George W.,Thakore, Chittam,Lu, Qun 전남대학교 약품개발연구소 2002 약품개발연구지 Vol.11 No.-

        Actin- and microtubule-mediated changes in cell shape are essential for many cellular activities. However, the molecular mechanisms underlying the interplay between the two are complex and remain obscure. Here we show that the expression of δ-catenin (or NPRAP/Neurojungin), a member of p120^ctm subfamily of armadillo proteins can induce the branching of dendrite-like processes in 3T3 cells and enhance dendritic morphogenesis in primary hippocampal neurons. This induction of branching phenotype involves initially the disruption of filamentous actin, and requires the growth of microtubules. The carboxyl-terminal truncation mutant of δ-catenin can cluster and redistribute the full-length protein, and dominantly inhibit its branching effect. δ-Catenin forms protein complexes and can bind directly to actin in vitro. The carboxyl-terminal truncation of δ-catenin does not interfere with its actin-binding capability; therefore the actin interaction alone is not sufficient for the induction of dendrite-like processes. When δ-catenin-transformed cells establish elaborate dendrite-like branches, the main cellular processes become stabilized and resist the disruption od both actin filaments and microscopy and time-lapse recording analyses. We suggest that δ-catenin can effect a biphasic cytoskeletal remodeling event which differentially regulates actin and microtubules and promotes cellular morphogenesis.

      • KCI등재

        Efficacy of indole-3-acetic acid-producing PGPFs and their consortium on physiological and biochemical parameters of Trigonella foenum-graecum L

        Thakor Rashmi,Mistry Harsh,Bariya Himanshu 한국원예학회 2023 Horticulture, Environment, and Biotechnology Vol.64 No.4

        Fungi produce phytohormones like indole-3-acetic acid (IAA), which stimulates the growth of plants. In the present study, Aspergillus niger (AN) and Aspergillus caespitosus (DS-3) were identifi ed in screens for highly effi cient IAA-producing fungi. Initially, IAA production was assessed through UV–Visible spectroscopic analysis using Salkowski’s reagent. HPTLC confi rmed the presence of IAA in all fungal extracts when compared with the standard IAA. HPTLC analysis revealed that AN exhibit the highest IAA production, which was 251.86 ± 0.7 μg ml −1 . AN, DS-3 and a combination of both strains as a growth-promoting consortium (GPC-1) were applied to Trigonella foenum-graecum L seeds for 6 h. After 14 days, the fenugreek plants were used for both the physiological and biochemical analysis. Results indicated that the GPC-1 induced more desirable physiological properties, with higher protein content, carbohydrate content, total phenolic content and antioxidant activity compared to treatment with individual PGPFs or distilled water. The extract from fenugreek plants treated with GPC-1 had the maximum diosgenin content (342.374 ± 0.67 μg ml −1 ), as assessed by HPTLC.

      • Neuron Selection Based on Deflection Coefficient Maximization for the Neural Decoding of Dexterous Finger Movements

        Yong-Hee Kim,Thakor, Nitish V.,Schieber, Marc H.,Hyoung-Nam Kim IEEE 2015 IEEE transactions on neural systems and rehabilita Vol.23 No.3

        <P>Future generations of brain-machine interface (BMI) will require more dexterous motion control such as hand and finger movements. Since a population of neurons in the primary motor cortex (M1) area is correlated with finger movements, neural activities recorded in M1 area are used to reconstruct an intended finger movement. In a BMI system, decoding discrete finger movements from a large number of input neurons does not guarantee a higher decoding accuracy in spite of the increase in computational burden. Hence, we hypothesize that selecting neurons important for coding dexterous flexion/extension of finger movements would improve the BMI performance. In this paper, two metrics are presented to quantitatively measure the importance of each neuron based on Bayes risk minimization and deflection coefficient maximization in a statistical decision problem. Since motor cortical neurons are active with movements of several different fingers, the proposed method is more suitable for a discrete decoding of flexion-extension finger movements than the previous methods for decoding reaching movements. In particular, the proposed metrics yielded high decoding accuracies across all subjects and also in the case of including six combined two-finger movements. While our data acquisition and analysis was done off-line and post processing, our results point to the significance of highly coding neurons in improving BMI performance.</P>

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