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- 저자 : Temperini (검색결과 3 건)
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Therapeutic Potential of Bauhinia forficata Link in Dental Biofilm Treatment
Julio Cesar C. Ferreira-Filho,Andressa Temperini de Oliveira Marre,Juliana Soares de Sa Almeida,Leandro de Araujo Lobo,Adriana Farah,Maria Teresa Villela Romanos,Lucianne Cople Maia,Ana Maria Gondim V 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.9
The oral cytotoxicity, antimicrobial and anti-demineralizing effects of a tincture from Bauhinia forficata Link tincture (BFLT) were evaluated in vitro and ex vivo. Susceptibility tests (minimum inhibitory and microbicidal concentrations-MIC and time-kill assay-MMC) were performed against planktonic oral microorganisms. The contents of phenolic compounds were investigated. Cytotoxic potential was evaluated on oral fibroblasts after 1–5 min exposure to BFLT. Blocks of sound bovine enamel (N = 60) were inoculated with a saliva pool and sustained in a multiple plaque growth system for 48 h to form a biofilm. Biofilm blocks were randomly divided into groups-G (n = 10): G1-Baseline (48 h maturation biofilm), G2-BFLT 23.2 mg/mL, G3-Ethanol 81.20 g/mL, G4-Chlorhexidine 0.12%, G5-Growth control, and G6-Blank control. Treatments (50 μL/1 min) were performed once a day for a week. Streptococcus spp. (S) and total microorganism (TM) counts were expressed as Log10 CFU/mL. Biofilm height was evaluated by confocal microscopy analyses (CMA). Final surface hardness was assessed and percentage of microhardness loss (% MHL) was calculated. Results were significant when P < .05. BFLT inhibited all tested microorganisms (MIC = 1.3–23.2 mg/mL) and promoted optical reduction (0.05–0.22 nm) of all microorganisms after 48-h treatment compared with controls. After 5-min treatment, BFLT showed low values of cell death (3.20%). G2-BFLT reduced S (6.61 ± 0.20) and TM (7.14 ± 0.38) compared with G1-Baseline (S = 7.82 ± 0.28; TM = 8.81 ± 0.67) and G5-Growth control (S = 7.48 ± 0.39; TM = 7.89 ± 0.68); but G4-chlororexidine (S = 6.11 ± 0.48; TM = 6.45 ± 0.16) showed the highest antibiofilm activity. CMA was not different among treatment groups. G2 showed lower % MHL compared with G5, although G4 presented the lowest. Results suggest BFLT is beneficial against dental caries, showing antimicrobial effects against a mature dental biofilm and no cytotoxicity.
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L.S.Pinheiro,M.L.A.Temperini 한국물리학회 2002 Current Applied Physics Vol.2 No.2
2-Mercaptopyrimidine (2MPy) forms a two-dimensional planar lattice on Au(111). This structure is able to intercalate guestmolecules such as the oligopyridines. To test the ability of the 2MPy lattice as a host able to intercalate a variety of moleculesregardless of their geometry and electronic structures, some arenes and polyenes were analyzed as possible guests. Benzene,naphthalene, azulene, phenanthrene, anthracene, biphenyl, uorobenzene and durene were selected to coadsorb with 2MPy on thesurfaces. The experimental data show that the arenes and polyenes selected coadsorb with 2MPy on Au(11) under dened ex-perimental conditions, forming a mixed layer with stoichiometry of 2:1 in thiol:guest. The STM contrast observed for the guestmolecules is compared to the experimental and theoretical results already published.. 2002 Elsevier Science B.V. All rights re-served.
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Problematizing customization and IT in the fashion industry: A case study of an Italian shoemaker
Andrea Perna,Andrea Runfola,Valerio Temperini,Gian Luca Gregori 한국마케팅과학회 2018 Journal of Global Fashion Marketing Vol.9 No.1
This paper focuses on the problematization of customization processes in the fashion industry. We investigate how companies may face and orchestrate customization processes that are based on the use of specifi c Information and Technology (IT) tools such as online sales confi gurators. Most studies on customization in fashion have considered the roles of consumers and their impact on the development of customization strategies. The co-development of customized goods – the choices concerning which IT system should be implemented to allow customers to design their products – has been studied extensively. We off er new insights into the extent to which customization represents an issue to be managed in business relationships, particularly among diff erent business actors involved in a supplier network. By considering the case of a shoe manufacturer we seek to answer to the following research questions: (1) How can a fashion company implement a customized solution via the Internet? (2) Which specifi c trade-off s aff ect the management of customization and IT when online customization must be linked to offl ine production? The paper concludes with implications and suggestions for further research.
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