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Takeshi Kanashima,Koji Ikeda,Masanori Okuyama,Masayuki Sohgawa,Taizo Tada 한국물리학회 2005 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.46 No.1
High-k HfO2 thin lms have been prepared mainly at 400 C in O2 atmosphere by pulsed laser deposition (PLD), and defects in the lm have been characterized by electron spin resonance (ESR). Two ESR peaks are found at g ' 2:003 and 2:006. The g ' 2:006 peak intensity is higher in the sample deposited at target-sample distance of 45 mm than in that deposited at 60 mm. This is because part of the substrate and the lm are exposed to high-energy particles ablated during deposition and are hence damaged. Moreover, the peak at g ' 2:006 is related to the interface state density calculated from the high-frequency C V curve. On the other hand, the peak at g ' 2:003 is related to the thickness of the interfacial layer, and thus may be attributed to defects in the interfacial layer.
Serum Periplakin as a Potential Biomarker for Urothelial Carcinoma of the Urinary Bladder
Matsumoto, Kazumasa,Ikeda, Masaomi,Matsumoto, Toshihide,Nagashio, Ryo,Nishimori, Takanori,Tomonaga, Takeshi,Nomura, Fumio,Sato, Yuichi,Kitasato, Hidero,Iwamura, Masatsugu Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22
The objectives of this study were to examine serum periplakin expression in patients with urothelial carcinoma of the urinary bladder and in normal controls, and to examine relationships with clinicopathological findings. Detection of serum periplakin was performed in 50 patients and 30 normal controls with anti-periplakin antibodies using the automatic dot blot system, and a micro-dot blot array with a 256 solid-pin system. Levels in patients with urothelial carcinoma of the urinary bladder were significantly lower than those in normal controls (0.31 and 5.68, respectively; p<0.0001). The area under the receiver-operator curve level for urothelial carcinoma of the urinary bladder was 0.845. The sensitivity and specificity, using a cut-off point of 4.045, were 83.7% and 73.3%, respectively. In addition, serum periplakin levels were significantly higher in patients with muscle-invasive cancer than in those with nonmuscle-invasive cancer (P = 0.03). In multivariate Cox proportional hazards regression analysis, none of the clinicopathological factors was associated with an increased risk for progression and cancer-specific survival. Examination of the serum periplakin level may play a role as a non-invasive diagnostic modality to aid urine cytology and cystoscopy.
Pressure and temperature conditions of upper mantle beneath the Jeju Island, Korea
YUN, Sung-Hyo,IKEDA, Takeshi,YANAGI, Takeru 부산대학교 과학교육연구소 2005 교사교육연구 Vol.44 No.-
Alkaline basalts erupted extensively on the back-arc side of the Japan arc in the Late Miocene to Quarternary. They commonly contain xenoliths of spinel peridotite. The spinel peridotites occurring as xenoliths in the Jeju Island, Korea, have preserved the equilibrium pressure- emperature conditions that range from 1000℃ and 14 kbar to 1100℃ and 22 kbar. This study evaluates the validity of these variations using a differential geothermobarometer even though previous studies have regarded them to have some uncertainties in the estimations. An upwelling of mantle beneath the Jeju Island may explain both the absolute values of these conditions and the their variations. 후기 마이오세에서 제4기에 이르는 동안 일본 도호의 배호(背弧)측에서는 알칼리현무암이 광범위에 걸쳐 분출되었다. 이들은 스피넬-페리도타이트 포획체를 공통적으로 가지고 있다. 한국 제주도에서 제4기 현무암에 포획체로 나타나는 스피넬-페리도타이트는 1000℃, 14Kbar에서 1100℃, 22Kbar의 범위에 이르는 평형 압력-온도 조건을 보존하고 있다. 선행 연구들이 평행 압력-온도 조건의 변화를 불확실한 의견으로 다루었음에도 불구하고, 본 연구는 차별된 지온지압계를 사용하여 이러한 조건 변화의 유효성을 검토하였다. 제주도 지하에서의 맨틀의 용승은 이러한 조건의 절대 값과 변화 값으로 설명될 수 있다.
Tanoue Shota,Nakaura Takeshi,Nagayama Yasunori,Uetani Hiroyuki,Ikeda Osamu,Yamashita Yasuyuki 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.6
Objective: To evaluate the usefulness of virtual monochromatic images (VMIs) obtained using dual-layer dual-energy CT (DL-DECT) for evaluating brain tumors. Materials and Methods: This retrospective study included 32 patients with brain tumors who had undergone non-contrast head CT using DL-DECT. Among them, 15 had glioblastoma (GBM), 7 had malignant lymphoma, 5 had high-grade glioma other than GBM, 3 had low-grade glioma, and 2 had metastatic tumors. Conventional polychromatic images and VMIs (40–200 keV at 10 keV intervals) were generated. We compared CT attenuation, image noise, contrast, and contrast-to-noise ratio (CNR) between tumor and white matter (WM) or grey matter (GM) between VMIs showing the highest CNR (optimized VMI) and conventional CT images using the paired t test. Two radiologists subjectively assessed the contrast, margin, noise, artifact, and diagnostic confidence of optimized VMIs and conventional images on a 4-point scale. Results: The image noise of VMIs at all energy levels tested was significantly lower than that of conventional CT images (p < 0.05). The 40-keV VMIs yielded the best CNR. Furthermore, both contrast and CNR between the tumor and WM were significantly higher in the 40 keV images than in the conventional CT images (p < 0.001); however, the contrast and CNR between tumor and GM were not significantly different (p = 0.47 and p = 0.31, respectively). The subjective scores assigned to contrast, margin, and diagnostic confidence were significantly higher for 40 keV images than for conventional CT images (p < 0.01). Conclusion: In head CT for patients with brain tumors, compared with conventional CT images, 40 keV VMIs from DL-DECT yielded superior tumor contrast and diagnostic confidence, especially for brain tumors located in the WM.