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- 저자 : Tahereh Tekieh (검색결과 2 건)
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Are deformed neurons electrophysiologically altered? A simulation study
Tahereh Tekieh,Sohrab Shahzadi,Hashem Rafii-Tabar,Pezhman Sasanpour 한국물리학회 2016 Current Applied Physics Vol.16 No.10
The electrophysiological outcome of neuron deformation is studied. This study is based on modeling the propagation of action potentials in a neuron with different deformed segments subject to an external mechanical compression. The proposed model is based on modified cable equation incorporating geometry variations. The study is performed for different degrees and number of deformations of the axon structure. The results of simulation show that the propagation speed, the refractory period, and the action potential broadening are all directly affected by variations in the geometry.
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Neurophysiological Effect of External Electromagnetic Field: A Computational Modeling
Tahereh Tekieh,Pezhman Sasanpour,Hashem Ra¯i-Tabar 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.10
The effect of an alternating external field on the pattern of an axon's action potential and its propagation has been investigated by incorporating the effect of an alternating electric field in the nonlinear Hodgkin–Huxley cable model. The results illustrate that for a wide range of frequencies, the applied field is capable of stimulating the resting potential of the membrane. In addition to hyper-polarization state of the neuron which is inevitable for certain values of the electric field amplitude, there will be additional effects on the propagation of action potentials in the neuron. We have also studied the action potentials velocity and amplitude change in the presence of the external field while the fiber is firing. The initiation of action potential for an axon at rest exposed to external field is possible and during the firing of the neuron and under the influence of the external field, it will act as a velocity modifier, and the neuron will lower the amplitude of the action potentials.
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