축산식품(畜産食品)의 잔류농약(殘留農藥)에 관(關)한 연구(硏究) 제(第) 3 보(報) 우유(牛乳) 및 식육중(食肉中) 유기염소제(有機鹽素劑)의 잔류량조사(殘留量調査)

조태행,황대우,이문한,이원창,Cho, Tae Haeng,Whang, Dae Woo,Lee, Moon Han,Lee, Won Chang 대한수의학회 1977 大韓獸醫學會誌 Vol.17 No.2

During the period of March, 1976 to December, 1976, 48 raw milk samples were taken from dairy cows at 48 different dairy farms in Korea analyzed by gas liquid chromatography to determine the seasonal variation of the amount of organochlorine pesticide residues. At the same time 80 market milk, 10 beef and 10 pork samples were analyed by the same procedure for checking residual levels. The results were summarized as follows; 1. Milk samples from 17 dairy farms (36 per cent of tatal) were shown to be contaminated with various organochlorine pesticides. The residua lrate of ${\gamma}-BHC$ in tested samples were 44per cent (14 sam ples) that of aldrine was 28 per cent (9 samples) and those of pp'-DDT, dieldrin and heptachlor were 9.3 percent (3 samples) respectively. 2. In raw milk pp'-DDT, ${\gamma}-BHC$, aldrin, dieldrin and heptachlor were detected, and aldrin, dieldrin and heptachlor were detected in the market milk. Any kinds of organochlorine pesticides were not detected in beef samples but dieldrin and heptachlor were detected in pork samples. Average residual values of aldrin, dieldrin and heptachlor in the market milk were 0.0077 ppm (0.0000~1.1100 ppm), 0.0001ppm (0.0000~0.0500 ppm) and 0.0008 ppm (0.0000~2.0520 ppm), respectively, and those of dieldrin and heptachlor in pork samples were 0.0010 ppm (0.0000~0.0100 ppm) and 0.0033 ppm (0.0000~0.0330 ppm). respectively. 3. Residues of organochlorine pesticides in raw milk were extremely variable; in fact pp'-DDT was detected in milk samples from A, B, C and D districts and endrin was not detected from all districts. The ${\gamma}-BHC$ and dieldrin were detected at the district of A, C and D, aldrin at the districts of A and C and heptachlor at the districts of both A and D. 4. Seasonal trends of residual values of organochlorine pesticides were, in general, noticeable. The residual level was much higher in Spring than in other seasons and showed the tendeney of decrease from spring through summer and autumn generally; in the case of pp'-DDT average residual values were 0.0121 ppm in spring, 0.0022 ppm in summer and not detected in autumn. But in winter ${\gamma}-BHC$ and aldrin residues were increased a little. Residual values in raw milk (when cow are fed on hay and silage) were appeared higher in winter than the other seasons. 5. Residues of organochlorine pesticides in raw milk were not related in respect to hygienic conditions of dairy farms pp'-DDT and heptachlor were, in general, detected in all farms and aldrin was more detected in milk from well sanitated farms than poor sanitated ones.

流通중 動物藥品 成分檢査成績(1987-1988)

Tae Haeng CHO(趙太行),Gab Soo CHUNG(鄭甲洙),Young Min IN(印英玟),Sun NAMGOONG(南宮琁) 한국예방수의학회 1989 예방수의학회지 Vol.13 No.1

A total of 454 samples consisted of the nutritives(134 samples) and therapeutics(320 samples) collected from the market during 1987-1988 was examined for the quality control of the animal drugs. A total of 50 cases(11.0%) out of 454 samples was recognized as unqualified. The number of items unqualified was 21 cases(6.6%) and 29 cases(21.6%) in the therapeutics and in the nutritives, respectively. Among the samples of 454, unqualified items with content-shortage were 40 cases(8.8%) and with content-11 cases(2.4%). The shortage in the therapeutice were 21 case all, whereas, in the nutritives 18 cases(13.4%) and 11 cases(8.2%), respectively.

市販鷄卵의 衛生學的 調査硏究

Tae Haeng CHO(趙太行),Young Min IN(印英玟),Gab Soo CHUNG(鄭甲洙),Seong Wan SON(孫性完),Jong Myung PARK(朴鍾鳴),Yong Dhuk YOON(尹用德),Sun NAMGOONG(南宮琁),Kenun Sik PARK(朴根植) 한국예방수의학회 1989 예방수의학회지 Vol.13 No.1

This studies were surveyed the actual states of the selling of chicken eggs at 35 poultry farms and 52 egg shops from march to october in 1988. Bacteriological and physicochemical tests against selling eggs were performed for establishment of egg sanitation. The results obtained were summarized as follows. Circulation process of the eggs was very complex. Shipping term of the eggs from poultry farms differentiated according to the scale. As scale of the poultry farms was larger, shipping term of the eggs was shorter. The necessary time of selling of the eggs at the salehouse differentiated according to wholesale stores and retail shops. In the physicochemical tests of the eggs, 103(23.3%) of 442 eggs disqualified in specific gravity, 79(14.2%) of 555 eggs in depth of air shell, 25(17.1%) of 146 eggs and 36(24.7%) of 146 eggs in pH of egg yolk and egg white, and 81(55%) of 147 eggs in coefficient of egg yolk. The selling eggs at the retail shops showed higher bacterial contamination than new eggs in colony forming units. Bacterial contamination level at parts of the eggs was orderly egg shell, egg white and egg yolk. No salmonellae detected all parts of the eggs.

牛乳用 紙栓의 螢光增白劑 檢出試驗

Tae Haeng Cho(趙太行),Jonghoo Cho(趙鍾厚) 한국예방수의학회 1978 예방수의학회지 Vol.2 No.1

Contamination of fluorescent bleaching agents in paper caps for milk bottle and various kinds of orginal paper tissue used for paper caps were examined by ultraviolet ray irradiation method, and also the possibilities of elution into milk and various kiqds of water tested. The results obtained were summarized as follows. 1. Fluorescent bleaching agents could not be detected. in paper caps newly developed since July, 1977. 2. Such original materials used for paper caps as rosin side, talc and aluminum sulfate rosin side only contained 1 mg fluorescent bleaching agent per ml. 3. Fluorescent bleaching agents were detected in typing paper, rough paper, reclaimed paper for toilet and paper box, while these could not be detected in filter paper, reference card paper and coping paper. 4. Fluorescent bleaching agents infiltrated in paper caps were not extracted in milk and various kinds of water.

流通중 收去 動物用醫藥品 檢査 成績(1991-1992)

Tae Haeng Cho(趙太行),Gab Soo Chung(鄭甲洙),Doo Hag Yun(尹斗鶴),Kwang Jick Lee(李光稙),Sun Namgoong(南宮琁) 한국예방수의학회 1993 예방수의학회지 Vol.17 No.1

A total of 731 samples consisted of the therapeutics (594 samples) and nutritives (137 samples) collected from the markets during 1991-1992 was examined for the quality control of the animal drugs. A total of 33 cases (4.5%) out of 731 samples was recognized as unqualified. The number of items unqualified was 23 cases (3.9%) and 10 cases (7.3%) in the therapeutics and the nutritives, respectively. Among the samples of 731, unqualified items with content-shortage were 29 cases (4.0%) and with content-surplus 4 cases (0.5% ). The shortage and surplus in the therapeutics were 22 cases (3.7%) and 1 case (0.2%), respectively.

抗生物質 amoxicillin 原料 및 salinomycin 添加劑의 安定性 調査

Tae Haeng Cho(趙太行),Kwang Jick Lee(李光稙),Sun Namgoong(南宮旋),Jae Chin Lee(李在鎭) 한국예방수의학회 1994 예방수의학회지 Vol.18 No.2

The amount of consumption of antibiotics including salinomycin and amoxicillin trihydrate has been growing day by day as a variety of disease occured in recent years. But the terms of validity of amoxicillin and salinomycin was not determined in Korea as yet. We examed the stability of amoxicillin trihydrate by checking the change of potency, pH, content of water and property under the ambient and stress condition (40℃, humidity 30~70%) and there was little change in potency, pH, content of water and property till the 30 months during the preservation time and salinomycin was same here so it will be possible to establish the terms of validity about 24 months in case of amoxicillin trihydrate and salinomycin feed additives.

1993年度 動物用 抗生物質製劑의 國家檢定成績

Tae Haeng Cho(趙太行),Kwang Jick Lee(李光植),Jae Jin Lee(李在鎭) 한국예방수의학회 1994 예방수의학회지 Vol.18 No.3

This report was results to be analyzed for quality control to animal using antibiotics of 30,651 lots duing the periods of 1963 to 1993. Among them, 30,461 lots are passed and 190 lots rejected through national assay. The preparation forms of animal using antibiotics of total 15,981 lots examined for 7 years (1987~1993) were classified as feed additives 5,437(34.0%), injectables 4,322(27.0%) and soluble powders including oral suspensions 3,972(24.9%), respectively. Of the antibiotics of 15,981 lots, 1,278 lots(8.0%) were applied for raw materials, 879 lots(5.5%) as implantations for therapy of bovine mastitis and 93 lots(0.6%) as the other antibiotics. In 1993, 1,910 lots of animal using antibiotics were examined by regulation of national assay. Among them 1,887 lots are passed and 23 lots rejected through national assay. During the periods of 1985 to 1993, 20,140 lots of antibiotics were test by regulation of national assay. Among them, 190 lots were rejected by results of national assay. By the preparation forms, the soluble powders including the oral suspensions were highly rejected 66 lots, and injectables, feed additives, implantations and the others were orderly rejected, 52, 52, 18 and 2 lots, respectively By reason of the rejection, 152 of 190 lots were insufficient potency, 24 excessive humidity, 11 high pH and 3 adequate characteristic tests, respectively

抗콕시듐劑 抗生物質의 닭 體內代謝 및 殘留에 關한 硏究

Tae Haeng Cho(趙太行),Kwang Jick Lee(李光稙),Sun Namgoong(南宮琁),Jong Myung Park(朴鍾鳴),Mun Han Lee(李文漢) 한국예방수의학회 1993 예방수의학회지 Vol.17 No.3

Detection for residues of polyether antibiotics(Salinomycin, Monensin, Lasalocid and Naracin) in chicken tissues-kidney, fat, liver and muscle was performed by the TLC and bioautography. B. subtillis ATCC 6633 strain, ethyl acetate and chlorform : methanol : conc. NH₄OH(95/5/0.5) solvent and addition of MgCl₂ in media were used in these experiments. Eighty chickens were divided four groups : 2 normal level feeder groups (monensin 110ppm, salinomycin 50ppm), 2 high level feeder groups(monensin 550ppm, salinomycin 250ppm) for five weeks. The recovery rate of monensin, salinomycin, lasalocid and naracin was 85.9~100.5%, 88.8%, 86.8% and 87.8% in chicken tissues at each. In high level feeder groups, monensin and salinomycin were detected about 0.052ppm and 0.085ppm at each in fat tissue at 24hours after feeding The duration of residues in high level feeder groups lasted longer than that of normal level feeder groups. Besides this test we have performed the amount of contamination of polyether antibiotics in twenty market chickens, so there is no residue of polyether antibiotics in the chiken tissue.

1963-1992年度 動物用抗生物질製劑의 國家檢定成績

Tae Haeng Cho(趙太行),Kwang Jick Lee(李光稙),Jong Myung Park(朴鍾鳴),Sun Namgoong(南宮琁),Keun Sik Park(朴根植) 한국예방수의학회 1993 예방수의학회지 Vol.17 No.1

This report was results to be analyzed for quality control to animal using antibiotics of 28, 741 lots during the periods of 1963 to 1992. Among them, 28, 574 lots are passed and 167 lots rejected through national assay. The preparation forms of animal using antibiotics of total 14, 071 lots examined for 6 years(1987-1992) were classified as feed additives 4, 781 (34.0%), injectables 3, 871 (27.5%) and soluble powders including oral suspensions 3,426(24.3%), respectively. Of the antibiotics of 14,071 lots, 1,182 lots(8.4%) were applied for raw materials, 733(5.2%) as implantations for therapy of bovine mastitis and 78 lots (0.6%) as the other antibiotics. In 1992, 2, 282 lots of animal using antibiotics were examined by regulations of national assay. Among them, mono-antimicrobial drugs were 1, 697 lots (74%) and combined antibiotics 585 lots (26%), respectively. The nomo-antibiotics and combined antibiotics were constituted with 58 kinds of chemical components. During the periods of 1985 to 1992, 18, 230 lots of antibiotics were tested by regulations of national assay. Among them, 167 lots were rejected by results of national assay. By the preparation forms, the soluble powders including the oral suspensions were highly rejected as 54 lots, and injectables, feed additives, implantations and the others were orderly rejected 49, 45, 17 and 2 lots, respectively. By reason of the rejection, 129 of 167 lots were insufficiently potency, 24 excessively humidity, 11 highly pH and 3 adequately characteristic tests, respectively.

産卵鷄에 抗生物質 添加飼料給與時 鷄卵의 殘留

Tae Haeng CHO(趙太行),Young Min IN(印英玟),Jong Myung PARK(朴鍾鳴),Sun NAMGOONG(南宮璇) 한국예방수의학회 1990 예방수의학회지 Vol.14 No.1

The layer chickens which were 440 days old of age were reared with feedstuffs containing zinc bacitracin(50 ppm and 250 ppm), virginiamycin(50 ppm and 250 ppm) and chlorotetracycline hydrochloride(200 ppm) for obtaining basic data of the antibiotic residue levels in eggs. The each experimental groups were designed as 110 layer chickens. The rearing procedures of these chickens were performed as described Yamakishi from April to November in 1989. The residues of antibiotics in the egg yolks and whites were assayed by paper disk method. The eggs from these chickens reared as feedstuffs containing 50 ppm virginiamycin and zinc bacitracin were not detected any antibiotics in the egg yolks and whites. In the eggs from these chickens, trace antibiotics were detected in the egg yolks and whites at 2 and/or 3 weeks after rearing with feedstuffs containing 250 ppm of virginiamycin and zinc bacitracin. When the chickens were fed as feedstuffs containing 200 ppm of chlorotetracycline hydrochloride, the antibiotic was detected trace levels in the egg yolks and whites at the 6th and 7th day. After 5 weeks reared with these feedstuffs, the residue levels of chlorotetracycline were detected 0.11 ppm in the egg yolks and 0.09 ppm in the egg whites, respectively. In the groups of the chickens reared with feedstuffs containing 250 ppm of virginiamycin and zinc bacitracin, the antibiotics were not detected in the egg yolks and whites as the 2nd and 3rd day after feeding discontinuance of the antibiotics. In case of the group of the chickens reared with feedstuffs containing 200 ppm of chlorotetracycline, the antibiotic was not detected in the egg yolks and whites at the 2nd day after feeding discontinuance of the antibiotic.