Recent progress on surface chemistry of plasmonic metal nanoparticles for colorimetric assay of drugs in pharmaceutical and biological samples

Kailasa, Suresh Kumar,Koduru, Janardhan Reddy,Desai, Mittal L.,Park, Tae Jung,Singhal, Rakesh Kumar,Basu, Hirakendu Elsevier 2018 Trends in analytical chemistry Vol.105 No.-

<P><B>Abstract</B></P> <P>Plasmonic metal nanoparticles have been explored as a new class of chemical read-outs for assaying of a variety of chemical and biological species because of their unique physico-chemical and size dependent properties. Metal nanoparticles-based optical technologies are based on either new class of organic molecular assembly or with aggregation-induced optical changes features, which can also improve the sensitivity of drug assays in pharmaceutical analysis. This review describes the advantages of surface chemistry of plasmonic metal nanoparticles (e.g., silver, copper, gold, and platinum) for tuning of their colorimetric sensing applications in various drugs assays in pharmaceutical and biological samples. It provides insights of various plasmonic metal nanoparticles-based sensing strategies for the selective, sensitive and simultaneous colorimetric assay of drugs in pharmaceutical samples. Finally, we listed some research challenges to accelerate the development of plasmonic metal nanoparticles-based colorimetric sensors that are directly applicable for assaying drugs in pharmaceutical samples.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Surface chemistry of plasmonic metal NPs plays key role in sensing of drugs. </LI> <LI> Progress on plasmonic metal NPs for assaying of various drugs is reviewed. </LI> <LI> Plasmonic metal NPs act as magnificent visual readouts for simultaneous analysis of drugs. </LI> <LI> Analytical performances of plasmonic metal NPs sensors were tabulated. </LI> </UL> </P>

Ultra-fast simultaneous analysis of genetically modified organisms in maize by microchip electrophoresis with LIF detector

Kumar, Kailasa Suresh,Kang, Seong Ho WILEY-VCH Verlag 2007 Electrophoresis Vol.28 No.22

<P>This study examined the potential of microchip electrophoresis (ME) with a LIF detector using a programmed field strength gradient (PFSG) in a conventional glass double-T microchip for the ultra-fast detection and simultaneous analysis of genetically modified (GM) maize. The separation efficiency and sensitivity at various sieving gels (poly(ethylene oxide) (PEO, M<SUB>r</SUB> 8 000 000) and 2-hydroxyethylcellulose (HEC) (M<SUB>r</SUB> 250 000)) and fluorescent dye concentrations were investigated. The PCR products of both the GM and non-GM maize were analyzed within 30 s under the PFSG (470.6 V/cm for 20 s, 117.6 V/cm for 12 s, and 470.6 V/cm for 30 s) with a 2.5% HEC sieving matrix in the running buffer, 1×Tris-borate EDTA (TBE) (pH 8.30) and 0.5 ppm ethidium bromide. The five transgenic maize varieties (Event176, MON810, Bt11, GA21, and T25) examined in this study were also clearly differentiated by ME-PFSG within 30 s in a single run without any loss of resolution. The ME-PFSG technique is a powerful tool for the ultra-fast detection and simultaneous analysis of GMOs in a variety of foods including maize.</P>

Influence of ligand chemistry on silver nanoparticles for colorimetric detection of Cr³⁺ and Hg²⁺ ions

Kailasa, Suresh Kumar,Chandel, Madhurya,Mehta, Vaibhavkumar N.,Park, Tae Jung Elsevier 2018 Spectrochimica acta. Part A, Molecular and biomole Vol.195 No.-

<P><B>Abstract</B></P> <P>In this work, we describe the role of ligand chemistry on the surfaces of silver nanoparticles (Ag NPs) for tuning their analytical applications. The citrate and melamine (MA) molecules were used as ligands for the surface modification of Ag NPs. The addition of Cr<SUP>3+</SUP> ion in citrate-Ag NPs (Cit-Ag NPs) and of Hg<SUP>2+</SUP> ion in melamine-Ag NPs (MA-Ag NPs) cause Ag NPs aggregation, and are accompanied by a color change and a red-shift. The resulting distinctly visual readouts are favorable for colorimetric detection of Cr<SUP>3+</SUP> and Hg<SUP>2+</SUP> ions. Under optimal conditions, the linear ranges are observed in the concentration ranges of 1.0–50.0 and of 10.0–100.0 μM, and with detection limit of 0.52 and 1.80 μM for Cr<SUP>3+</SUP> and Hg<SUP>2+</SUP> ions. The simultaneous detection of Cr<SUP>3+</SUP> and Hg<SUP>2+</SUP> ion is driven by the changing the ligand chemistry on the surfaces of Ag NPs that allows to tune their specific interactions with target analytes. Finally, the functionalized Ag NPs were successfully applied to detect Cr<SUP>3+</SUP> and Hg<SUP>2+</SUP> ions in water samples with satisfactory recoveries.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Tuning of Ag NPs colorimetric sensing applications with ligand chemistry </LI> <LI> Citrate- and MA-Ag NPs show high selectivity towards Cr<SUP>3+</SUP> and Hg<SUP>2+</SUP> ions over other metal ions. </LI> <LI> The sensors exhibit good linearities for Cr<SUP>3+</SUP> and Hg<SUP>2+</SUP> ion with limits of detection at micromolar range. </LI> <LI> This method was successfully applied to detect both ions in water samples. </LI> <LI> The developed sensors exhibit good accuracy and precision. </LI> </UL> </P> <P><B>Graphical Abstract</B></P> <P>Schematic representation of influence of ligand chemistry on Ag NPs surfaces for tuning of their analytical applications.</P> <P>[DISPLAY OMISSION]</P>

Electrospray ionization tandem mass spectrometry for rapid, sensitive and direct detection of melamine in dairy products

Suresh Kumar Kailasa,Hui-Fen Wu 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.21 No.1

A simple, rapid, and sensitive method for detection of melamine in dairy products by electrosprayionization mass spectrometry (ESI–MS) without any sample preparation is demonstrated. The ESI–MS/MS on the protonated melamine atm/z 127 produced the characteristic fragment ions atm/z 110, 85, 68,60. This method has a good linearity in the range of 0.5–10.0 mg/mL, with detection limit 0.1 mg/mL andRSD 8.9% (n = 5). Together with existing recent methods on mass spectrometry and NP-based sensingmethodologies for melamine detection, the present method provides an efficient platform for detectionof melamine in milk products without any sample preparation steps or post-separation procedures.

Progress of electrospray ionization and rapid evaporative ionization mass spectrometric techniques for the broad-range identification of microorganisms

Kailasa, Suresh Kumar,Koduru, Janardhan Reddy,Park, Tae Jung,Wu, Hui-Fen,Lin, Ying-Chi Royal Society of Chemistry 2019 The Analyst Vol.144 No.4

<P>Several non-culture molecular (multiplex polymerase chain reaction assays, DNA microarrays, massive parallel DNA sequencing, <I>in situ</I> hybridization, microbiome profiling, and molecular typing of pathogens) and analytical (electrophoresis, gel electrophoresis, surface-enhanced Raman scattering, and mass spectrometry) tools have been developed in recent years for the identification of bacteria and diagnosis of bacterial infections from clinical samples. Among mass spectrometric techniques, electrospray ionization (ESI) and rapid evaporative ionization (REI) mass spectrometric (MS) techniques have attracted much attention in the identification of microorganisms (bacteria, fungi, and viruses), and in the diagnosis of various bacterial infections. This review highlights the developed ESI-MS-based methods, including polymerase chain reaction (PCR) combined with ESI-MS and capillary electrophoresis (CE) and liquid chromatography (LC)-ESI-MS, for the identification of microorganisms (pathogenic bacteria, fungi, and viruses) in various samples. Recent applications of ESI- and REI-MS in identifying pathogenic bacteria are depicted in tables, and some significant findings are summarized.</P>

Biofiltration of hydrogen sulfide: Trends and challenges

Vikrant, Kumar,Kailasa, Suresh Kumar,Tsang, Daniel C.W.,Lee, Sang Soo,Kumar, Pawan,Giri, Balendu Shekhar,Singh, Ram Sharan,Kim, Ki-Hyun Elsevier 2018 JOURNAL OF CLEANER PRODUCTION Vol.187 No.-

<P><B>Abstract</B></P> <P>Expansion of modern industry coupled with a lack of effective treatment systems has resulted in excessive release of toxic and odorous pollutants such as hydrogen sulfide (H<SUB>2</SUB>S). Development of treatment measures is therefore necessary to protect ecosystems and human health. This paper explores recent advances in H<SUB>2</SUB>S treatment technologies. Particular focus is placed on innovative and recent advances in biofiltration, especially for wastewater treatment facilities and biogas generation (e.g., use of innovative packing media for better performance and reduced pressure drop, eliminating sulfate accumulation, and development of modeling techniques). The review also identifies current challenges and future prospects (e.g., fluctuations in methane and carbon dioxide concentrations during biogas upgradation, optimizing anoxic H<SUB>2</SUB>S biofiltration, and understanding the effects of operating conditions on biofilter performance) for improving biofiltration by highlighting research gaps in related fields.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Hydrogen sulfide (H<SUB>2</SUB>S) is a water-soluble gas with the characteristic malodor. </LI> <LI> In this review, we briefly discussed the physicochemical properties and sources of H<SUB>2</SUB>S. </LI> <LI> We dealt biological approaches for the removal of H<SUB>2</SUB>S. </LI> <LI> The challenges and prospects related to these treatment methods are also described. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Advances in functional nanomaterial-based electrochemical techniques for screening of endocrine disrupting chemicals in various sample matrices

Azzouz, Abdelmonaim,Kailasa, Suresh Kumar,Kumar, Pawan,Ballesteros, Evaristo,Kim, Ki-Hyun Elsevier 2019 Trends in analytical chemistry Vol.113 No.-

<P><B>Abstract</B></P> <P>This review was organized to describe the progress made in the integration of nanostructural materials into electrochemical analytical tools for the quantification of endocrine disrupting chemicals (EDCs) in diverse sample matrices (e.g., environmental and biological samples). Here, we focused mainly on seven major EDCs: alkylphenols/phenols, bisphenol A, parabens, triclosan, phthalates, pesticides, and natural/synthetic sex hormones. All of them are known to exhibit endocrine disruption by strong binding with estrogen receptors to pose serious health risks (e.g., cancerous tumors and disorders in various organs). To realize rapid, selective, and sensitive detection of EDCs, the use of nanostructured materials has become a fascinating option due to many merits (e.g., automation, fast response, good accuracy, and high selectivity/sensitivity). Here, the performance of sensing tools built using nanomaterials was assessed for the detection of EDCs in various sample matrices. Our discussion was extended further to cover the future prospects on this fascinating research field.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Recently, noticeable achievements have been made in electrochemical sensing of EDCs. </LI> <LI> This review summarizes the integration of functional materials into various electrodevices for EDC. </LI> <LI> Quantification of major EDCs is described to including bisphenol A in different types of samples. </LI> <LI> The results will offer valuable insights into the new possibilities and prospects for EDC detection. </LI> </UL> </P>

Review of nanomaterials as sorbents in solid-phase extraction for environmental samples

Azzouz, Abdelmonaim,Kailasa, Suresh Kumar,Lee, Sang Soo,J. Rascó,n, André,s,Ballesteros, Evaristo,Zhang, Ming,Kim, Ki-Hyun Elsevier 2018 Trends in analytical chemistry Vol.108 No.-

<P><B>Abstract</B></P> <P>Anthropogenic organic contaminants (AOCs) are found to exert significant impacts on the human ecosystem, even at low or trace-level concentrations. To meet the growing demand for their quantitation in diverse environmental media, the use of preconcentration approaches (such as solid phase extraction) has become an essential component to practically upgrade both procedural efficiency and the analytical sensitivity. Nanomaterials (NMs) are realized as excellent candidates for proper sorption media because of their unique structural and surface properties with noticeably enhanced sorption capability towards contaminants. This review explores the use of various NMs (metallic and mixed oxide nanoparticles (NPs), carbon NMs (fullerenes, carbon nanotubes, graphene, and graphene oxide), polymer-based nanocomposites (organic polymers, inorganic and hybrid polymers, molecularly imprinted polymers, and dendrimers), and silicon/magnetic NPs) as potential sorbents for analytical applications. In this review, the distinctive features of NM-based sorptive extraction techniques are examined comprehensively with the discussion on their future prospects and key challenges.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Applications of nanomaterials in sorptive extraction techniques are overviewed. </LI> <LI> Extraction efficiency of sorptive extraction was improved using nanomaterials. </LI> <LI> This review highlights the integration of nanomaterials with sorptive extraction techniques. </LI> <LI> The prospects of nanomaterials technology in trace level analysis are described. </LI> </UL> </P>

A critical review of ferrate(VI)-based remediation of soil and groundwater

Rai, Prabhat Kumar,Lee, Jechan,Kailasa, Suresh Kumar,Kwon, Eilhann E.,Tsang, Yiu Fai,Ok, Yong Sik,Kim, Ki-Hyun Elsevier 2018 Environmental research Vol.160 No.-

<P><B>Abstract</B></P> <P>Over the past few decades, diverse chemicals and materials such as mono- and bimetallic nanoparticles, metal oxides, and zeolites have been used for soil and groundwater remediation. Ferrate (Fe<SUP>VI</SUP>O<SUB>4</SUB> <SUP>2-</SUP>) has been widely employed due to its high-valent iron (VI) oxo compound with high oxidation/reduction potentials. Ferrate has received attention for wide environmental applications including water purification and sewage sludge treatment. Ferrate provides great potential for diverse environmental applications without any environmental problems. Therefore, this paper provides comprehensive information on the recent progress on the use of (Fe<SUP>VI</SUP>O<SUB>4</SUB> <SUP>2-</SUP>) as a green material for use in sustainable treatment processes, especially for soil and water remediation. We reviewed diverse synthesis recipes for ferrates (Fe<SUP>VI</SUP>O<SUB>4</SUB> <SUP>2-</SUP>) and their associated physicochemical properties as oxidants, coagulants, and disinfectants for the elimination of a diverse range of chemical and biological species from water/wastewater samples. A summary of the eco-sustainable performance of ferrate(VI) in water remediation is also provided and the future of ferrate(VI) is discussed in this review.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Ferrate(VI) has exhibited promising behavior towards the oxidation of inorganic/organic impurities. </LI> <LI> It has unique properties of strong oxidizing potential and generation of ferric coagulating species. </LI> <LI> It can degrade and/or oxidize organic and inorganic impurities (at least partially). </LI> <LI> It can also disinfect microorganisms and remove suspended/colloidal particulate materials. </LI> <LI> We reviewed on the preparation, properties, and role of ferrate to resolve multifaceted challenges. </LI> </UL> </P>

Progress on nanostructured electrochemical sensors and their recognition elements for detection of mycotoxins: A review

Goud, K. Yugender,Kailasa, Suresh Kumar,Kumar, Vanish,Tsang, Yiu Fai,Lee, S.E.,Gobi, K. Vengatajalabathy,Kim, Ki-Hyun Elsevier 2018 Biosensors & bioelectronics Vol.121 No.-

<P><B>Abstract</B></P> <P>Nanomaterial-embedded sensors have been developed and applied to monitor various targets. Mycotoxins are fungal secondary metabolites that can exert carcinogenic, mutagenic, teratogenic, immunotoxic, and estrogenic effects on humans and animals. Consequently, the need for the proper regulation on foodstuff and feed materials has been recognized from times long past. This review provides an overview of recent developments in electrochemical sensors and biosensors employed for the detection of mycotoxins. Basic aspects of the toxicity of mycotoxins and the implications of their detection are comprehensively discussed. Furthermore, the development of different molecular recognition elements and nanomaterials required for the detection of mycotoxins (such as portable biosensing systems for point-of-care analysis) is described. The current capabilities, limitations, and future challenges in mycotoxin detection and analysis are also addressed.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Mycotoxins are fungal secondary metabolites that exert toxic effects on humans and animals. </LI> <LI> Exploration of mycotoxins is an interdisciplinary research area that has progressed intensively. </LI> <LI> Different nanomaterials (NMs) were used for the detection of small molecules, including mycotoxins. </LI> <LI> Here the recent developments of NM-based EC biosensors are described for mycotoxin detection. </LI> <LI> The role of EC sensors is assessed for combined applications with diverse recognition elements. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>