Disseminated histoplasmosis diagnosed on bone marrow aspiration in an immunocompetent patient

Sunita Sharma,Shivali Sehgal 대한혈액학회 2015 Blood Research Vol.50 No.3

None

Disseminated histoplasmosis diagnosed on bone marrow aspiration in an immunocompetent patient

Sunita Sharma,Shivali Sehgal 대한혈액학회 2015 Blood Research Vol.50 No.3

None

Acute promyelocytic leukemia with an unusual presentation of secondary postpartum hemorrhage

Sunita Sharma,Mukta Pujani,Narender Tejwani 대한혈액학회 2013 Blood Research Vol.48 No.4

Micronutrients and superoxide dismutase in postmenopausal women with chronic periodontitis: a pilot interventional study

Sunita Daiya,Rajinder Kumar Sharma,Shikha Tewari,Satish Chander Narula,Paramjeet Kumar Sehgal 대한치주과학회 2014 Journal of Periodontal & Implant Science Vol.44 No.4

Purpose: The study was aimed at investigating changes in periodontal parameters and superoxide dismutase activity triggered by root surface debridement with and without micronutrient supplementation in postmenopausal women. Methods: Forty-three postmenopausal chronic periodontitis patients were divided into two groups: group 1 (n=22) were provided periodontal treatment in the form of scaling and root planing (SRP) and group 2 (n=21) patients received SRP along with systemic administration of micronutrient antioxidants. Patients in both groups were subjected to root surface debridement. Group 2 patients also received adjunctive micronutrient antioxidant supplementation. Serum and salivary superoxide dismutase (SOD) activity along with periodontal parameters were recorded at baseline and 3 months after therapy. Results: Salivary and serum SOD values significantly (P<0.05) improved with periodontal treatment. Improvement in systemic enzymatic antioxidant status along with reduction in gingival inflammation and bleeding on probing (%) sites was significantly greater in group 2 as compared to group 1. Conclusions: Adjunctive micronutrient supplements reduce periodontal inflammation and improve the status of systemic enzymatic antioxidants in postmenopausal women.

Critical review on graph theory: Estimation of thermodynamic properties of liquid mixtures

Malik Sunita,Sharma V. K. 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.11

The present work deals with a review on graph theory that has been utilized to estimate thermodynamic properties of binary and ternary liquid mixtures. Various topological indices have been used to describe the topology of the chemical species it presents. Elegance and versatility of connectivity parameters of third degree of molecules, 3ξ, of the various components (derived from their topology) of mixtures are used to estimate (i) existence of components in mixture as well as pure state along with the extent and nature of the interaction between the constituent molecules; (ii) excess molar volume, VE, excess isentropic compressibility, κ E S, excess molar enthalpy, HE, excess heat capacity, C E P, excess Gibb’s energy, GE of binary and ternary liquid mixtures. The present review reports the development of graph theory and its utilization for the determination of VE, κ E S, HE, C E P, GE of two/three component mixtures (components being non-polar, polar differing in size, shape, polarity and ionic liquids).

Micronutrients and superoxide dismutase in postmenopausal women with chronic periodontitis: a pilot interventional study

Daiya, Sunita,Sharma, Rajinder Kumar,Tewari, Shikha,Narula, Satish Chander,Sehgal, Paramjeet Kumar Korean Academy of Periodontology 2014 Journal of Periodontal & Implant Science Vol.44 No.4

Purpose: The study was aimed at investigating changes in periodontal parameters and superoxide dismutase activity triggered by root surface debridement with and without micronutrient supplementation in postmenopausal women. Methods: Forty-three postmenopausal chronic periodontitis patients were divided into two groups: group 1 (n=22) were provided periodontal treatment in the form of scaling and root planing (SRP) and group 2 (n=21) patients received SRP along with systemic administration of micronutrient antioxidants. Patients in both groups were subjected to root surface debridement. Group 2 patients also received adjunctive micronutrient antioxidant supplementation. Serum and salivary superoxide dismutase (SOD) activity along with periodontal parameters were recorded at baseline and 3 months after therapy. Results: Salivary and serum SOD values significantly (P<0.05) improved with periodontal treatment. Improvement in systemic enzymatic antioxidant status along with reduction in gingival inflammation and bleeding on probing (%) sites was significantly greater in group 2 as compared to group 1. Conclusions: Adjunctive micronutrient supplements reduce periodontal inflammation and improve the status of systemic enzymatic antioxidants in postmenopausal women.

Effect of myofascial release and muscle energy technique on patients with chronic neck pain: a scoping review

Sneha Mittal,Sunita Sharma 한국운동영양학회 2024 Physical Activity and Nutrition (Phys Act Nutr) Vol.28 No.1

[Purpose] To identify the effects of muscle energy techniques and myofascial release in patients with chronic neck pain. [Methods] To conduct a literature search and identification; PRISMA-ScR guidelines were followed. Relevant articles were searched for from the following medical and health sciences electronic databases: PubMed, EBSCOhost, CENTRAL of the Cochrane Library, and the Physiotherapy Evidence-Based Database (PEDro). Patients with chronic neck pain were eligible for the scoping review. [Results] Seven articles were included in this review. This scoping review found that there is heterogeneity in the prescription of MFR and MET and a greater tendency to check three major physical dimensions (pain, range of motion, and disability). Various studies have opted for distinct intervention regimens, resulting in disparities in the frequency of weekly interventions, which can range from biweekly to five times a week. These inconsistencies may lead to perplexity among practitioners, as each intervention modality demonstrates favorable outcomes for individuals with persistent cervical discomfort. Moreover, a significant proportion of research projects have employed the numeric pain rating scale (NPRS) and visual analog scale (VAS) for data quantification. [Conclusion] According to results, majority of the studies were focused on pain and missing components of range of motion and quality of life. Work-related factors can act as risk factors for chronic neck pain. Future investigations should adopt a comprehensive methodology and incorporate QoL assessments of quality of life.

Hepcidin and iron parameters in children with anemia of chronic disease and iron deficiency anemia

Gunjan Mahajan,Sunita Sharma,Jagdish Chandra,Anita Nangia 대한혈액학회 2017 Blood Research Vol.52 No.3

Background: Anemia of chronic disease (ACD) and iron deficiency anemia (IDA) are the two most preva-lent forms of anemia having interrelated characteristics. Hepcidin, a newly introduced biomarker for assessment of iron status, is a homeostatic regulator of iron metabolism. We investigated the role of hepcidin and other conventional iron parameters to assess iron status among children with ACD and IDA. We also identified children with ACD who developed iron deficiency (ID). Methods: The study was undertaken in anemic children with 30 cases each of ACD and IDA along with 30 age and sex-matched controls. The ACD cases were subdivided into pure ACD and ACD with coexistent ID. All cases were subjected to following tests: complete blood count with peripheral smear, serum C-reactive protein, serum interleukin-6, iron studies, serum soluble transferrin receptor (sTfR), and serum hepcidin. Results: The mean serum hepcidin concentration was significantly increased in pure ACD patients (143.85±42.76 ng/mL) as compared to those in IDA patients (6.01±2.83 ng/mL, P<0.001) and controls (24.96±9.09 ng/mL, P<0.001). Also, compared to pure ACD pa-tients [normal sTfR levels (<3 μg/mL)], the serum hepcidin concentration was reduced significantly in ACD patients with ID [high sTfR levels (≥3 μg/mL)] with a mean of 10.0±2.97 ng/mL. Conclusion: Hepcidin measurement can provide a useful tool for differentiating ACD from IDA and also help to identify an iron deficiency in ACD patients. This might aid in the appropriate selection of therapy for these patients.

Hepcidin and iron parameters in children with anemia of chronic disease and iron deficiency anemia

Gunjan Mahajan,Sunita Sharma,Jagdish Chandra,Anita Nangia 대한혈액학회 2017 Blood Research Vol.52 No.3

Background: Anemia of chronic disease (ACD) and iron deficiency anemia (IDA) are the two most preva-lent forms of anemia having interrelated characteristics. Hepcidin, a newly introduced biomarker for assessment of iron status, is a homeostatic regulator of iron metabolism. We investigated the role of hepcidin and other conventional iron parameters to assess iron status among children with ACD and IDA. We also identified children with ACD who developed iron deficiency (ID). Methods: The study was undertaken in anemic children with 30 cases each of ACD and IDA along with 30 age and sex-matched controls. The ACD cases were subdivided into pure ACD and ACD with coexistent ID. All cases were subjected to following tests: complete blood count with peripheral smear, serum C-reactive protein, serum interleukin-6, iron studies, serum soluble transferrin receptor (sTfR), and serum hepcidin. Results: The mean serum hepcidin concentration was significantly increased in pure ACD patients (143.85±42.76 ng/mL) as compared to those in IDA patients (6.01±2.83 ng/mL, P<0.001) and controls (24.96±9.09 ng/mL, P<0.001). Also, compared to pure ACD pa-tients [normal sTfR levels (<3 μg/mL)], the serum hepcidin concentration was reduced significantly in ACD patients with ID [high sTfR levels (≥3 μg/mL)] with a mean of 10.0±2.97 ng/mL. Conclusion: Hepcidin measurement can provide a useful tool for differentiating ACD from IDA and also help to identify an iron deficiency in ACD patients. This might aid in the appropriate selection of therapy for these patients.

Chronicles of blood morphology associated with steroid use

Kavita Gaur,Vandana Puri,Shailaja Shukla,Sunita Sharma 대한혈액학회 2019 Blood Research Vol.54 No.3

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